AT352726B - Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen - Google Patents

Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen

Info

Publication number
AT352726B
AT352726B AT823776A AT823776A AT352726B AT 352726 B AT352726 B AT 352726B AT 823776 A AT823776 A AT 823776A AT 823776 A AT823776 A AT 823776A AT 352726 B AT352726 B AT 352726B
Authority
AT
Austria
Prior art keywords
salts
piperidine derivatives
producing new
new piperidine
producing
Prior art date
Application number
AT823776A
Other languages
English (en)
Other versions
ATA823776A (de
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Priority to AT712578A priority Critical patent/AT360020B/de
Priority to AT712478A priority patent/AT360019B/de
Publication of ATA823776A publication Critical patent/ATA823776A/de
Application granted granted Critical
Publication of AT352726B publication Critical patent/AT352726B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT823776A 1975-11-07 1976-11-05 Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen AT352726B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT712578A AT360020B (de) 1975-11-07 1978-10-03 Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen
AT712478A AT360019B (de) 1975-11-07 1978-10-03 Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752549999 DE2549999A1 (de) 1975-11-07 1975-11-07 Piperidin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ATA823776A ATA823776A (de) 1979-03-15
AT352726B true AT352726B (de) 1979-10-10

Family

ID=5961166

Family Applications (1)

Application Number Title Priority Date Filing Date
AT823776A AT352726B (de) 1975-11-07 1976-11-05 Verfahren zur herstellung von neuen piperidin- derivaten und deren salzen

Country Status (20)

Country Link
US (1) US4243807A (de)
JP (1) JPS6055509B2 (de)
AT (1) AT352726B (de)
BE (1) BE847973A (de)
CA (1) CA1077942A (de)
CH (3) CH624102A5 (de)
DD (1) DD126942A5 (de)
DE (1) DE2549999A1 (de)
DK (1) DK494876A (de)
FI (1) FI763148A (de)
FR (1) FR2330678A1 (de)
GB (1) GB1502050A (de)
HU (1) HU171237B (de)
IE (1) IE43866B1 (de)
IT (1) IT1063618B (de)
LU (1) LU76141A1 (de)
NL (1) NL7612286A (de)
SE (1) SE7612234L (de)
SU (3) SU633473A3 (de)
ZA (1) ZA766381B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848275B (en) * 1983-12-28 1985-08-28 Degussa New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
US4556664A (en) * 1984-03-13 1985-12-03 Gunnar A. K. Aberg Method and composition for the treatment of cardiac arrhythmias
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5231184A (en) * 1987-11-23 1993-07-27 Janssen Pharmaceutica N.V. Pridazinamine derivatives
US4822778A (en) * 1988-01-19 1989-04-18 Gunnar Aberg Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
US5264420A (en) * 1990-09-27 1993-11-23 Merck & Co., Inc. Fibrinogen receptor antagonists
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
HUT68769A (en) * 1991-05-07 1995-07-28 Merck & Co Inc FIBRINOGéN RECEPTOR ANTAGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AS EFFECTIVE SUBSTANCE
US5321034A (en) * 1991-05-07 1994-06-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5272158A (en) * 1991-10-29 1993-12-21 Merck & Co., Inc. Fibrinogen receptor antagonists
US5416099A (en) * 1991-10-29 1995-05-16 Merck & Co., Inc. Fibrinogen receptor antagonists
US5389631A (en) * 1991-10-29 1995-02-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5358956A (en) * 1992-10-14 1994-10-25 Merck & Co., Inc. Fibrinogen receptor antagonists
EP0664792B1 (de) * 1992-10-14 2000-01-05 Merck & Co. Inc. Fibrinogenrezeptor-antagonisten
CA2150550A1 (en) * 1992-12-01 1994-06-09 Melissa S. Egbertson Fibrinogen receptor antagonists
US5441952A (en) * 1993-04-05 1995-08-15 Merck & Co., Inc. Fibrinogen receptor antagonists
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
US5397791A (en) * 1993-08-09 1995-03-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5821241A (en) * 1994-02-22 1998-10-13 Merck & Co., Inc. Fibrinogen receptor antagonists
US5719144A (en) * 1995-02-22 1998-02-17 Merck & Co., Inc. Fibrinogen receptor antagonists
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
KR100403246B1 (ko) * 1995-09-28 2004-02-11 가켄 세이야쿠 가부시키가이샤 4-메틸렌피페리딘의제조방법
US5789421A (en) * 1995-10-26 1998-08-04 Merck & Co., Inc. Fibrinogen receptor antagonist
US5780480A (en) * 1996-02-28 1998-07-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5889023A (en) * 1996-05-10 1999-03-30 Merck & Co., Inc. Fibrinogen receptor antagonist
US5981584A (en) * 1997-02-06 1999-11-09 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
TWI438190B (zh) * 2008-07-24 2014-05-21 Theravance Inc 3-(苯氧基苯基甲基)吡咯啶化合物
CA2742105C (en) 2008-11-14 2016-09-13 Theravance, Inc. 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds
US20100267743A1 (en) * 2009-04-15 2010-10-21 Stangeland Eric L 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
CN102471258A (zh) * 2009-07-13 2012-05-23 施万制药 3-苯氧基甲基吡咯烷化合物
JP5714580B2 (ja) 2009-07-21 2015-05-07 セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー 3−フェノキシメチルピロリジン化合物
US8778949B2 (en) * 2010-01-11 2014-07-15 Theravance Biopharma R&D Ip, Llc 1-(2-phenoxymethylphenyl)piperazine compounds
WO2011119461A1 (en) * 2010-03-22 2011-09-29 Theravance, Inc. 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds
WO2012051103A1 (en) 2010-10-11 2012-04-19 Theravance, Inc. Serotonin reuptake inhibitors
WO2012075239A1 (en) 2010-12-03 2012-06-07 Theravance, Inc. Serotonin reuptake inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268951A (en) * 1969-06-12 1972-03-29 Pfizer Ltd Phenoxy-amines
DE2245061A1 (de) * 1972-09-14 1974-03-28 Boehringer Mannheim Gmbh Derivate des adenins
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IE43866B1 (en) 1981-06-17
FI763148A (de) 1977-05-08
LU76141A1 (de) 1977-05-18
JPS5259163A (en) 1977-05-16
DD126942A5 (de) 1977-08-24
FR2330678A1 (fr) 1977-06-03
BE847973A (fr) 1977-05-04
NL7612286A (nl) 1977-05-10
ZA766381B (en) 1977-10-26
HU171237B (hu) 1977-12-28
IT1063618B (it) 1985-02-11
SU867298A3 (ru) 1981-09-23
JPS6055509B2 (ja) 1985-12-05
SU633473A3 (ru) 1978-11-15
CH624102A5 (de) 1981-07-15
CH625788A5 (de) 1981-10-15
ATA823776A (de) 1979-03-15
CH627166A5 (de) 1981-12-31
SU662009A3 (ru) 1979-05-05
FR2330678B1 (de) 1980-11-07
DE2549999C2 (de) 1989-01-26
DK494876A (da) 1977-05-08
SE7612234L (sv) 1977-05-07
DE2549999A1 (de) 1977-05-12
GB1502050A (en) 1978-02-22
IE43866L (en) 1977-05-07
CA1077942A (en) 1980-05-20
US4243807A (en) 1981-01-06

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Legal Events

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ELJ Ceased due to non-payment of the annual fee