AT350576B - Verfahren zur herstellung von neuen phenoxy- derivaten und von deren salzen - Google Patents

Verfahren zur herstellung von neuen phenoxy- derivaten und von deren salzen

Info

Publication number
AT350576B
AT350576B AT534376A AT534376A AT350576B AT 350576 B AT350576 B AT 350576B AT 534376 A AT534376 A AT 534376A AT 534376 A AT534376 A AT 534376A AT 350576 B AT350576 B AT 350576B
Authority
AT
Austria
Prior art keywords
salts
producing new
phenoxy derivatives
new phenoxy
derivatives
Prior art date
Application number
AT534376A
Other languages
English (en)
Other versions
ATA534376A (de
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Application granted granted Critical
Publication of AT350576B publication Critical patent/AT350576B/de
Publication of ATA534376A publication Critical patent/ATA534376A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT534376A 1975-07-21 1976-07-20 Verfahren zur herstellung von neuen phenoxy- derivaten und von deren salzen AT350576B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30392/75A GB1489711A (en) 1975-07-21 1975-07-21 1-phenoxyphenyl-piperazine derivatives process for their preparation and pharmaceutical compositions containing the

Publications (2)

Publication Number Publication Date
AT350576B true AT350576B (de) 1978-06-15
ATA534376A ATA534376A (de) 1978-11-15

Family

ID=10306953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT534376A AT350576B (de) 1975-07-21 1976-07-20 Verfahren zur herstellung von neuen phenoxy- derivaten und von deren salzen

Country Status (21)

Country Link
US (1) US4064245A (de)
JP (1) JPS5225783A (de)
AR (1) AR211273A1 (de)
AT (1) AT350576B (de)
AU (1) AU498329B2 (de)
BE (1) BE844343A (de)
CA (1) CA1085400A (de)
CH (1) CH595368A5 (de)
DE (1) DE2631885C2 (de)
ES (1) ES450012A1 (de)
FR (1) FR2318634A1 (de)
GB (1) GB1489711A (de)
GR (1) GR61593B (de)
IE (1) IE43258B1 (de)
MX (1) MX3413E (de)
NL (1) NL162075C (de)
OA (1) OA05385A (de)
PH (1) PH12743A (de)
PT (1) PT65380B (de)
YU (1) YU163075A (de)
ZA (1) ZA764305B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210646A (en) * 1978-04-11 1980-07-01 Janssen Pharmaceutica N.V. Antimicrobial compositions containing 1-(aryloxyphenyl)piperazines
DE3235589A1 (de) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung
JPS63174868U (de) * 1987-04-14 1988-11-14
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
WO2007078335A2 (en) * 2005-12-21 2007-07-12 Decode Genetics, Ehf. Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation
TW200932233A (en) * 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
US10568882B2 (en) 2015-08-21 2020-02-25 Srx Cardio, Llc Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
US10865185B2 (en) 2015-08-21 2020-12-15 Srx Cardio, Llc Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
US10821106B2 (en) 2015-08-21 2020-11-03 Srx Cardio, Llc Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity
US20190119236A1 (en) 2016-02-23 2019-04-25 Portola Pharmaceuticals, Inc. Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9)
SG11202101307PA (en) * 2018-08-24 2021-03-30 Xeniopro GmbH Aromatic molecules for use in the treatment of pathological conditions

Also Published As

Publication number Publication date
CA1085400A (fr) 1980-09-09
DE2631885C2 (de) 1982-07-15
AR211273A1 (es) 1977-11-15
PT65380A (fr) 1976-08-01
NL7608007A (nl) 1977-01-25
JPS558504B2 (de) 1980-03-04
GB1489711A (en) 1977-10-26
NL162075B (nl) 1979-11-15
BE844343A (fr) 1977-01-20
OA05385A (fr) 1981-02-28
IE43258L (en) 1977-01-21
FR2318634A1 (fr) 1977-02-18
ATA534376A (de) 1978-11-15
GR61593B (en) 1978-12-02
FR2318634B1 (de) 1979-06-29
NL162075C (nl) 1980-04-15
DE2631885A1 (de) 1977-02-10
AU1603976A (en) 1978-01-26
PT65380B (fr) 1978-01-19
ES450012A1 (es) 1977-07-16
YU163075A (en) 1982-05-31
CH595368A5 (de) 1978-02-15
AU498329B2 (en) 1979-03-01
US4064245A (en) 1977-12-20
ZA764305B (en) 1977-07-27
PH12743A (en) 1979-08-09
MX3413E (es) 1980-11-07
JPS5225783A (en) 1977-02-25
IE43258B1 (en) 1981-01-14

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