BE844343A - Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique

Info

Publication number
BE844343A
BE844343A BE169088A BE169088A BE844343A BE 844343 A BE844343 A BE 844343A BE 169088 A BE169088 A BE 169088A BE 169088 A BE169088 A BE 169088A BE 844343 A BE844343 A BE 844343A
Authority
BE
Belgium
Prior art keywords
therapeutics
application
preparation process
phenoxy derivatives
new phenoxy
Prior art date
Application number
BE169088A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE844343A publication Critical patent/BE844343A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE169088A 1975-07-21 1976-07-20 Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique BE844343A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30392/75A GB1489711A (en) 1975-07-21 1975-07-21 1-phenoxyphenyl-piperazine derivatives process for their preparation and pharmaceutical compositions containing the

Publications (1)

Publication Number Publication Date
BE844343A true BE844343A (fr) 1977-01-20

Family

ID=10306953

Family Applications (1)

Application Number Title Priority Date Filing Date
BE169088A BE844343A (fr) 1975-07-21 1976-07-20 Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique

Country Status (21)

Country Link
US (1) US4064245A (fr)
JP (1) JPS5225783A (fr)
AR (1) AR211273A1 (fr)
AT (1) AT350576B (fr)
AU (1) AU498329B2 (fr)
BE (1) BE844343A (fr)
CA (1) CA1085400A (fr)
CH (1) CH595368A5 (fr)
DE (1) DE2631885C2 (fr)
ES (1) ES450012A1 (fr)
FR (1) FR2318634A1 (fr)
GB (1) GB1489711A (fr)
GR (1) GR61593B (fr)
IE (1) IE43258B1 (fr)
MX (1) MX3413E (fr)
NL (1) NL162075C (fr)
OA (1) OA05385A (fr)
PH (1) PH12743A (fr)
PT (1) PT65380B (fr)
YU (1) YU163075A (fr)
ZA (1) ZA764305B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210646A (en) * 1978-04-11 1980-07-01 Janssen Pharmaceutica N.V. Antimicrobial compositions containing 1-(aryloxyphenyl)piperazines
DE3235589A1 (de) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung
JPS63174868U (fr) * 1987-04-14 1988-11-14
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
EP1968961A2 (fr) 2005-12-21 2008-09-17 Decode Genetics EHF Inhibiteurs de biaryl-azote-heterocycle de lta4h pour traiter l'inflammation
TW200932233A (en) * 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
EP3337564A4 (fr) 2015-08-21 2019-01-23 Portola Pharmaceuticals, Inc. Composition et procédés d'utilisation de petites molécules de type tétrahydroisoquinoline pour se lier à pcsk9 et moduler l'activité protéique de pcsk9
EP3337497B1 (fr) 2015-08-21 2023-07-12 SRX Cardio, LLC Composition et procédés d'utilisation de nouveaux petits composés organiques de phénylalanine pour moduler directement l'activité de la protéine pcsk9
US10568882B2 (en) 2015-08-21 2020-02-25 Srx Cardio, Llc Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
US20190119236A1 (en) 2016-02-23 2019-04-25 Portola Pharmaceuticals, Inc. Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9)
JP2021534212A (ja) * 2018-08-24 2021-12-09 ゼニオプロ ゲーエムベーハー 病的状態の治療における使用のための芳香族分子

Also Published As

Publication number Publication date
AU1603976A (en) 1978-01-26
DE2631885A1 (de) 1977-02-10
AT350576B (de) 1978-06-15
ATA534376A (de) 1978-11-15
GB1489711A (en) 1977-10-26
ES450012A1 (es) 1977-07-16
PT65380B (fr) 1978-01-19
NL7608007A (nl) 1977-01-25
FR2318634A1 (fr) 1977-02-18
NL162075C (nl) 1980-04-15
FR2318634B1 (fr) 1979-06-29
CH595368A5 (fr) 1978-02-15
PT65380A (fr) 1976-08-01
OA05385A (fr) 1981-02-28
JPS5225783A (en) 1977-02-25
AR211273A1 (es) 1977-11-15
NL162075B (nl) 1979-11-15
YU163075A (en) 1982-05-31
AU498329B2 (en) 1979-03-01
PH12743A (en) 1979-08-09
GR61593B (en) 1978-12-02
IE43258B1 (en) 1981-01-14
US4064245A (en) 1977-12-20
DE2631885C2 (de) 1982-07-15
ZA764305B (en) 1977-07-27
IE43258L (en) 1977-01-21
CA1085400A (fr) 1980-09-09
JPS558504B2 (fr) 1980-03-04
MX3413E (es) 1980-11-07

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