JPS5225783A - Preparation method of new phenoxy derivatives - Google Patents

Preparation method of new phenoxy derivatives

Info

Publication number
JPS5225783A
JPS5225783A JP51086491A JP8649176A JPS5225783A JP S5225783 A JPS5225783 A JP S5225783A JP 51086491 A JP51086491 A JP 51086491A JP 8649176 A JP8649176 A JP 8649176A JP S5225783 A JPS5225783 A JP S5225783A
Authority
JP
Japan
Prior art keywords
preparation
phenoxy derivatives
new phenoxy
new
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51086491A
Other languages
English (en)
Other versions
JPS558504B2 (ja
Inventor
Beregi Rasutsuro
Ugoon Pieeru
Doyuooru Jiyatsuku
Buranjiyu Mishieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of JPS5225783A publication Critical patent/JPS5225783A/ja
Publication of JPS558504B2 publication Critical patent/JPS558504B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP51086491A 1975-07-21 1976-07-20 Preparation method of new phenoxy derivatives Granted JPS5225783A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30392/75A GB1489711A (en) 1975-07-21 1975-07-21 1-phenoxyphenyl-piperazine derivatives process for their preparation and pharmaceutical compositions containing the

Publications (2)

Publication Number Publication Date
JPS5225783A true JPS5225783A (en) 1977-02-25
JPS558504B2 JPS558504B2 (ja) 1980-03-04

Family

ID=10306953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51086491A Granted JPS5225783A (en) 1975-07-21 1976-07-20 Preparation method of new phenoxy derivatives

Country Status (21)

Country Link
US (1) US4064245A (ja)
JP (1) JPS5225783A (ja)
AR (1) AR211273A1 (ja)
AT (1) AT350576B (ja)
AU (1) AU498329B2 (ja)
BE (1) BE844343A (ja)
CA (1) CA1085400A (ja)
CH (1) CH595368A5 (ja)
DE (1) DE2631885C2 (ja)
ES (1) ES450012A1 (ja)
FR (1) FR2318634A1 (ja)
GB (1) GB1489711A (ja)
GR (1) GR61593B (ja)
IE (1) IE43258B1 (ja)
MX (1) MX3413E (ja)
NL (1) NL162075C (ja)
OA (1) OA05385A (ja)
PH (1) PH12743A (ja)
PT (1) PT65380B (ja)
YU (1) YU163075A (ja)
ZA (1) ZA764305B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021534212A (ja) * 2018-08-24 2021-12-09 ゼニオプロ ゲーエムベーハー 病的状態の治療における使用のための芳香族分子

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210646A (en) * 1978-04-11 1980-07-01 Janssen Pharmaceutica N.V. Antimicrobial compositions containing 1-(aryloxyphenyl)piperazines
DE3235589A1 (de) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung
JPS63174868U (ja) * 1987-04-14 1988-11-14
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
US7750012B2 (en) 2005-12-21 2010-07-06 Decode Genetics Ehf Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
TW200932233A (en) * 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
EP3337497B1 (en) 2015-08-21 2023-07-12 SRX Cardio, LLC Composition and methods of use of novel phenylalanine small organic compounds to directly modulate pcsk9 protein activity
WO2017034997A1 (en) * 2015-08-21 2017-03-02 Portola Pharmaceuticals, Inc. Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (pcsk9) modulators and their use
WO2017034990A1 (en) 2015-08-21 2017-03-02 Portola Pharmaceuticals, Inc. Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate pcsk9 protein activity
US20190119236A1 (en) 2016-02-23 2019-04-25 Portola Pharmaceuticals, Inc. Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021534212A (ja) * 2018-08-24 2021-12-09 ゼニオプロ ゲーエムベーハー 病的状態の治療における使用のための芳香族分子

Also Published As

Publication number Publication date
FR2318634A1 (fr) 1977-02-18
JPS558504B2 (ja) 1980-03-04
FR2318634B1 (ja) 1979-06-29
BE844343A (fr) 1977-01-20
AU1603976A (en) 1978-01-26
IE43258L (en) 1977-01-21
ATA534376A (de) 1978-11-15
PT65380B (fr) 1978-01-19
MX3413E (es) 1980-11-07
AU498329B2 (en) 1979-03-01
DE2631885A1 (de) 1977-02-10
ZA764305B (en) 1977-07-27
NL7608007A (nl) 1977-01-25
CH595368A5 (ja) 1978-02-15
YU163075A (en) 1982-05-31
GR61593B (en) 1978-12-02
AR211273A1 (es) 1977-11-15
ES450012A1 (es) 1977-07-16
CA1085400A (fr) 1980-09-09
NL162075C (nl) 1980-04-15
US4064245A (en) 1977-12-20
DE2631885C2 (de) 1982-07-15
AT350576B (de) 1978-06-15
IE43258B1 (en) 1981-01-14
NL162075B (nl) 1979-11-15
GB1489711A (en) 1977-10-26
PT65380A (fr) 1976-08-01
PH12743A (en) 1979-08-09
OA05385A (fr) 1981-02-28

Similar Documents

Publication Publication Date Title
BG24673A3 (en) Method of obtaining quinazone derivatives
GR60854B (en) Preparation process of benzylidenic derivatives
GR59797B (en) Preparation process of thieno-pyridine derivatives
BG27554A3 (en) Method of obtaining of derivatives of 2- aroyl- 3- phenyl- bewzothiophenes
JPS5231086A (en) Preparation method of circular syloxane
JPS51136672A (en) Preparation method of 33methylpyridine
JPS51113878A (en) Preparation method of new indolylpiperidine
JPS5225783A (en) Preparation method of new phenoxy derivatives
GR61995B (en) Preparation process of novel phenoxy hydroxypropylamine derivatives
BG30778A3 (en) Method for obtaining of eburnamenine derivatives
GR59205B (en) New preparation method of methoxy-2-benzamides derivative
CS194236B2 (en) Method of preparing derivatives of 4-oxo-hexahydro-4h-pyrazino-isoquinoline
JPS5217478A (en) New homophthalimide derivatives and preparation method thereof
JPS51141873A (en) Preparation method of flavone derivatives
JPS51146476A (en) New preparation method of quinolinee33carbonic acid
JPS5278874A (en) Method of preparation of 44hydroxypiperidines from 44oxopiperidines
JPS51115485A (en) Preparation method of quinoxalineedioxide derivatives
BG27555A3 (en) Method of obtaining of derivatives of aroyl- phenilnaphtalenes
JPS51125088A (en) Preparation method of new benzhydryloxyyalkylamine derivatives
JPS52274A (en) New preparation method of tetrahydrooalphaapyron derivatives
JPS51128973A (en) Preparation method of aminopyridine
JPS51138685A (en) Preparation method of 22aminoo 33hydroxypyridin derivatives
GR58595B (en) Preparation method of thieno-pyridines derivatives
JPS5219680A (en) Preparation method of chlorothianthrene
CS189006B2 (en) Method of preparation of tetrahydro-4-oxo-naftyl-urea compounds