AT340895B - Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen

Info

Publication number
AT340895B
AT340895B AT195476A AT195476A AT340895B AT 340895 B AT340895 B AT 340895B AT 195476 A AT195476 A AT 195476A AT 195476 A AT195476 A AT 195476A AT 340895 B AT340895 B AT 340895B
Authority
AT
Austria
Prior art keywords
trifluormethylacylophenone
oximathers
aminoathyl
acid addition
addition salts
Prior art date
Application number
AT195476A
Other languages
English (en)
Other versions
ATA195476A (de
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Priority to AT41377A priority Critical patent/AT342568B/de
Priority to AT317277A priority patent/AT342574B/de
Publication of ATA195476A publication Critical patent/ATA195476A/de
Application granted granted Critical
Publication of AT340895B publication Critical patent/AT340895B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT195476A 1975-03-20 1976-03-17 Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen AT340895B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT41377A AT342568B (de) 1975-03-20 1977-01-24 Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
AT317277A AT342574B (de) 1975-03-20 1977-05-04 Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (2)

Publication Number Publication Date
ATA195476A ATA195476A (de) 1977-05-15
AT340895B true AT340895B (de) 1978-01-10

Family

ID=19823424

Family Applications (1)

Application Number Title Priority Date Filing Date
AT195476A AT340895B (de) 1975-03-20 1976-03-17 Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen

Country Status (27)

Country Link
US (1) US4085225A (de)
JP (1) JPS6026776B2 (de)
AR (2) AR211011A1 (de)
AT (1) AT340895B (de)
AU (1) AU505358B2 (de)
BE (1) BE839744A (de)
CA (1) CA1076142A (de)
CH (4) CH626057A5 (de)
DD (1) DD128332A5 (de)
DE (1) DE2610886A1 (de)
DK (1) DK144942C (de)
ES (1) ES446192A1 (de)
FI (1) FI61875C (de)
FR (1) FR2304336A1 (de)
GB (1) GB1535226A (de)
GR (1) GR60052B (de)
HU (1) HU171030B (de)
IE (1) IE43768B1 (de)
IL (1) IL49238A (de)
IT (1) IT1063064B (de)
MX (1) MX9203723A (de)
NL (1) NL7503310A (de)
PL (3) PL100614B1 (de)
SE (1) SE410312B (de)
SU (3) SU635867A3 (de)
YU (1) YU39345B (de)
ZA (1) ZA761434B (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
ATE192042T1 (de) * 1995-08-16 2000-05-15 Lilly Co Eli Potenzierung von serotonin-wirkstoffresponz
IN182588B (de) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (de) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
CA2406383A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research A.beta.42 lowering agents
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
AU2001255654B2 (en) 2000-04-24 2005-09-22 Aryx Therapeutics Materials and methods for the treatment of depression
AU2002342045C1 (en) * 2001-10-12 2009-07-30 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin Vla antagonists
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
WO2005065069A2 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
EP1663398B1 (de) 2003-09-12 2009-11-25 Pfizer Limited Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern
JP4864719B2 (ja) * 2003-11-26 2012-02-01 ファイザー・プロダクツ・インク Ｇｓｋ−３インヒビターとしてのアミノピラゾール誘導体
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
EP1737473A4 (de) * 2004-04-19 2009-08-26 Noven Therapeutics Llc Lithium-kombinationen und relevante verwendungen
EP1745180A1 (de) * 2004-04-29 2007-01-24 Keystone Retaining Wall Systems, Inc. Frontverkleidung für stützwände
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
AU2006227199A1 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
JP2008538572A (ja) 2005-04-22 2008-10-30 ワイス ジヒドロベンゾフラン誘導体およびその使用
JP2008538573A (ja) 2005-04-22 2008-10-30 ワイス ベンゾフラニルアルカナミン誘導体およびその５−ｈｔ２ｃアゴニストとしての使用
MX2007013179A (es) * 2005-04-22 2008-01-16 Wyeth Corp Formas cristalinas de clorhidrato de {[(2r)-7-(diclorofenil)-5- fluoro-2,3-dihidro-1-benzofurano-2-il]metil}amina.
EP1871356A1 (de) * 2005-04-22 2008-01-02 Wyeth a Corporation of the State of Delaware Dihydrobenzofuran-derivate und verwendungen dafür
EP1904843A2 (de) 2005-07-08 2008-04-02 Braincells, Inc. Verfahren zur identifizierung von mitteln und zuständen für neurogenese-modulation
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
DK1910346T3 (da) 2005-07-19 2019-05-27 Azevan Pharmaceuticals Inc Beta-lactamyl fenylalanin, cystein og serin vasopressin antagonist
US20070042034A1 (en) * 2005-07-22 2007-02-22 Myriad Genetics, Incorporated High drug load formulations and dosage forms
EP2377530A3 (de) 2005-10-21 2012-06-20 Braincells, Inc. Modulation von Neurogenese durch PDE-Hemmung
EP1942879A1 (de) 2005-10-31 2008-07-16 Braincells, Inc. Gaba-rezeptor-vermittelte modulation von neurogenese
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
RU2008135326A (ru) * 2006-03-24 2010-04-27 Вайет (Us) Терапевтические композиции для лечения депрессии
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
EP2021000A2 (de) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenese mittels angiotensin-modulation
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
WO2008034032A2 (en) * 2006-09-14 2008-03-20 Azevan Pharmaceuticals, Inc. Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
WO2008086483A2 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation of neurogenesis with use of modafinil
EP2288345B1 (de) 2008-04-18 2015-06-10 University College Dublin National University Of Ireland, Dublin Psychopharmazeutika
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
ME02437B (de) 2009-10-23 2016-09-20 Janssen Pharmaceutica Nv Disubstituierte octahy-dropyrrolo [3,4-c]pyrrole als orexinrezeptormodulatoren
WO2011071995A2 (en) 2009-12-08 2011-06-16 Case Western Reserve University Compounds and methods of treating ocular disorders
EP2587919B1 (de) 2010-07-01 2017-12-13 Azevan Pharmaceuticals, Inc. Verfahren zur behandlung posttraumatischer belastungsstörungen
MX2013010598A (es) 2011-03-17 2014-01-08 Lupin Ltd Composiciones farmaceuticas de liberacion controlada de inhibidor de recaptacion de serotonina selectivo.
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
US9783492B2 (en) 2013-04-03 2017-10-10 Zcl Chemicals Limited Process for the preparation of fluvoxamine maleate
CN106456578B (zh) 2014-02-07 2020-02-18 匈牙利科学院大学及其他机构附属研究所 Sigma-1受体激动剂化合物的用途
SG11201608064WA (en) 2014-03-28 2016-10-28 Azevan Pharmaceuticals Inc Compositions and methods for treating neurodegenerative diseases
EA201891930A1 (ru) 2016-03-10 2019-02-28 Янссен Фармацевтика Нв Способы лечения депрессии с использованием антагонистов орексиновых рецепторов-2
CN110337244B (zh) 2016-11-24 2023-07-21 西格玛研究有限责任公司 用于器官保藏的组合物
KR102790657B1 (ko) 2017-09-15 2025-04-02 아제반 파마슈티칼스, 인코퍼레이티드 뇌 손상을 치료하기 위한 조성물 및 방법
AU2020316013A1 (en) 2019-07-19 2022-02-17 Arx, Llc Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
GR60052B (en) 1978-04-04
ZA761434B (en) 1977-10-26
MX9203723A (es) 1992-07-01
SE410312B (sv) 1979-10-08
SU635867A3 (ru) 1978-11-30
DK115976A (da) 1976-09-21
DK144942B (da) 1982-07-12
HU171030B (hu) 1977-10-28
FR2304336A1 (fr) 1976-10-15
JPS6026776B2 (ja) 1985-06-25
SU645559A3 (ru) 1979-01-30
DD128332A5 (de) 1977-11-09
IL49238A (en) 1978-08-31
GB1535226A (en) 1978-12-13
IE43768L (en) 1976-09-20
PL101951B1 (pl) 1979-02-28
AU505358B2 (en) 1979-11-15
FR2304336B1 (de) 1979-09-28
IE43768B1 (en) 1981-05-20
SU620206A3 (ru) 1978-08-15
FI61875B (fi) 1982-06-30
YU39345B (en) 1984-10-31
AR211153A1 (es) 1977-10-31
AU1214776A (en) 1977-09-22
US4085225A (en) 1978-04-18
AR211011A1 (es) 1977-10-14
CH629184A5 (de) 1982-04-15
ATA195476A (de) 1977-05-15
NL7503310A (nl) 1976-09-22
YU71476A (en) 1982-10-31
IL49238A0 (en) 1976-05-31
JPS51125345A (en) 1976-11-01
DE2610886A1 (de) 1976-10-07
ES446192A1 (es) 1977-10-01
PL100614B1 (pl) 1978-10-31
FI61875C (fi) 1982-10-11
SE7603341L (sv) 1976-09-21
CH629761A5 (de) 1982-05-14
IT1063064B (it) 1985-02-11
CH626057A5 (de) 1981-10-30
PL100052B1 (pl) 1978-08-31
CH629477A5 (de) 1982-04-30
FI760699A7 (de) 1976-09-21
DE2610886C2 (de) 1987-09-24
BE839744A (fr) 1976-09-20
CA1076142A (en) 1980-04-22
DK144942C (da) 1982-12-06

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