IL49238A - O-aminoethyl trifluoromethyl-phenyl-ketoximes, their preparation and pharmaceutical compositions containing them - Google Patents

O-aminoethyl trifluoromethyl-phenyl-ketoximes, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL49238A
IL49238A IL49238A IL4923876A IL49238A IL 49238 A IL49238 A IL 49238A IL 49238 A IL49238 A IL 49238A IL 4923876 A IL4923876 A IL 4923876A IL 49238 A IL49238 A IL 49238A
Authority
IL
Israel
Prior art keywords
ketoximes
aminoethyl
trifluoromethyl
phenyl
preparation
Prior art date
Application number
IL49238A
Other languages
English (en)
Other versions
IL49238A0 (en
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Publication of IL49238A0 publication Critical patent/IL49238A0/xx
Publication of IL49238A publication Critical patent/IL49238A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/50Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL49238A 1975-03-20 1976-03-17 O-aminoethyl trifluoromethyl-phenyl-ketoximes, their preparation and pharmaceutical compositions containing them IL49238A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (2)

Publication Number Publication Date
IL49238A0 IL49238A0 (en) 1976-05-31
IL49238A true IL49238A (en) 1978-08-31

Family

ID=19823424

Family Applications (1)

Application Number Title Priority Date Filing Date
IL49238A IL49238A (en) 1975-03-20 1976-03-17 O-aminoethyl trifluoromethyl-phenyl-ketoximes, their preparation and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (1) US4085225A (de)
JP (1) JPS6026776B2 (de)
AR (2) AR211011A1 (de)
AT (1) AT340895B (de)
AU (1) AU505358B2 (de)
BE (1) BE839744A (de)
CA (1) CA1076142A (de)
CH (4) CH626057A5 (de)
DD (1) DD128332A5 (de)
DE (1) DE2610886A1 (de)
DK (1) DK144942C (de)
ES (1) ES446192A1 (de)
FI (1) FI61875C (de)
FR (1) FR2304336A1 (de)
GB (1) GB1535226A (de)
GR (1) GR60052B (de)
HU (1) HU171030B (de)
IE (1) IE43768B1 (de)
IL (1) IL49238A (de)
IT (1) IT1063064B (de)
MX (1) MX9203723A (de)
NL (1) NL7503310A (de)
PL (3) PL100614B1 (de)
SE (1) SE410312B (de)
SU (3) SU635867A3 (de)
YU (1) YU39345B (de)
ZA (1) ZA761434B (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
WO1997006792A1 (en) * 1995-08-16 1997-02-27 Eli Lilly And Company Potentiation of serotonin response
IN182588B (de) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (de) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
WO2001078721A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research Aβ42 LOWERING AGENTS
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
JP2003531169A (ja) * 2000-04-24 2003-10-21 アリックス セラピューティクス うつ病治療のための材料と方法
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
CA2462903C (en) * 2001-10-12 2011-09-20 Serenix Pharmaceuticals, Llc Beta-lactamyl vasopressin v1a antagonists
EP2316469A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
WO2005065069A2 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
DE602004024317D1 (de) 2003-09-12 2010-01-07 Pfizer Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern
DE602004028150D1 (de) * 2003-11-26 2010-08-26 Pfizer Prod Inc Aminopyrazolderivate als gsk-3-inhibitoren
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
US20050233010A1 (en) * 2004-04-19 2005-10-20 Satow Philip M Lithium combinations, and uses related thereto
KR20070004036A (ko) * 2004-04-29 2007-01-05 키스톤 리테이닝 월 시스템스, 아이엔씨 벽, 옹벽 및 그 외 유사한 것을 위한 베니어
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006102283A2 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
PE20061298A1 (es) 2005-04-22 2006-12-24 Wyeth Corp Compuestos derivados de dihidrobenzofurano como agonistas del receptor de serotonina 5-ht2c
WO2006116151A1 (en) * 2005-04-22 2006-11-02 Wyeth Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists
JP2008538577A (ja) * 2005-04-22 2008-10-30 ワイス ジヒドロベンゾフラン誘導体およびその使用
JP2008538581A (ja) * 2005-04-22 2008-10-30 ワイス {[(2r)−7−(2,6−ジクロロフェニル)−5−フルオロ−2,3−ジヒドロ−1−ベンゾフラン−2−イル]メチル}アミン塩酸塩の結晶形態
AU2006269231A1 (en) 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
EP1910346B1 (de) * 2005-07-19 2019-02-27 Azevan Pharmaceuticals, Inc. Beta-lactamyl-phenylalanin, -cystein und -serin als vasopressinantagonisten
BRPI0613611A2 (pt) * 2005-07-22 2011-01-18 Myriad Genetics Inc formulações de alta concentração de fármaco e formas de dosagens
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス,インコーポレイティド 神経発生のgaba受容体媒介調節
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CN101410112A (zh) * 2006-03-24 2009-04-15 惠氏公司 治疗抑郁症的新治疗组合
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
EP2046119A2 (de) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Behandlung von psychiatrischen störungen
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
WO2008034032A2 (en) * 2006-09-14 2008-03-20 Azevan Pharmaceuticals, Inc. Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
EP2125017A2 (de) * 2007-01-11 2009-12-02 Braincells, Inc. Neurogenese-modulation durch verwendung von modafinil
EP2288345B1 (de) 2008-04-18 2015-06-10 University College Dublin National University Of Ireland, Dublin Psychopharmazeutika
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
ME02437B (de) 2009-10-23 2016-09-20 Janssen Pharmaceutica Nv Disubstituierte octahy-dropyrrolo [3,4-c]pyrrole als orexinrezeptormodulatoren
JP5815552B2 (ja) 2009-12-08 2015-11-17 ケース ウェスタン リザーブ ユニバーシティCase Westernreserve University 眼疾患を治療する化合物および方法
CN107007596A (zh) 2010-07-01 2017-08-04 阿泽凡药物公司 用于治疗创伤后应激障碍的方法
PH12013501900A1 (en) 2011-03-17 2017-08-23 Lupin Ltd Controlled release pharmaceutical compositions of selective serotonin reuptake inhibitor
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
WO2014178064A2 (en) * 2013-04-03 2014-11-06 Zcl Chemicals Limited "an improved process for the preparation of fluvoxamine maleate"
CN106456578B (zh) 2014-02-07 2020-02-18 匈牙利科学院大学及其他机构附属研究所 Sigma-1受体激动剂化合物的用途
WO2015148962A1 (en) 2014-03-28 2015-10-01 Azevan Pharmaceuticals, Inc. Compositions and methods for treating neurodegenerative diseases
IL288321B2 (en) 2016-03-10 2025-08-01 Janssen Pharmaceutica Nv Methods of treating depression using orexin-2 receptor antagonists
ES2926179T3 (es) 2016-11-24 2022-10-24 Sigmadrugs Kutato Korlatolt Feleloessegue Tarsasag Utilización de composiciones para la conservación de órganos/tejidos
JP2020534274A (ja) 2017-09-15 2020-11-26 アゼヴァン ファーマシューティカルズ,インコーポレイテッド 脳損傷を治療するための組成物及び方法
EP3999058A4 (de) 2019-07-19 2023-05-03 Bioxcel Therapeutics, Inc. Behandlungsschemata für nicht-sedierendes dexmedetomidin
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
CH629184A5 (de) 1982-04-15
SU620206A3 (ru) 1978-08-15
JPS6026776B2 (ja) 1985-06-25
GR60052B (en) 1978-04-04
SU645559A3 (ru) 1979-01-30
FR2304336A1 (fr) 1976-10-15
FI61875C (fi) 1982-10-11
SE410312B (sv) 1979-10-08
AU1214776A (en) 1977-09-22
MX9203723A (es) 1992-07-01
HU171030B (hu) 1977-10-28
AR211011A1 (es) 1977-10-14
FI760699A7 (de) 1976-09-21
ZA761434B (en) 1977-10-26
AU505358B2 (en) 1979-11-15
DK115976A (da) 1976-09-21
IT1063064B (it) 1985-02-11
YU39345B (en) 1984-10-31
BE839744A (fr) 1976-09-20
PL100052B1 (pl) 1978-08-31
GB1535226A (en) 1978-12-13
JPS51125345A (en) 1976-11-01
DD128332A5 (de) 1977-11-09
ATA195476A (de) 1977-05-15
DK144942B (da) 1982-07-12
AR211153A1 (es) 1977-10-31
DK144942C (da) 1982-12-06
PL100614B1 (pl) 1978-10-31
IE43768L (en) 1976-09-20
CH629761A5 (de) 1982-05-14
CH626057A5 (de) 1981-10-30
FR2304336B1 (de) 1979-09-28
IE43768B1 (en) 1981-05-20
AT340895B (de) 1978-01-10
ES446192A1 (es) 1977-10-01
NL7503310A (nl) 1976-09-22
CH629477A5 (de) 1982-04-30
DE2610886C2 (de) 1987-09-24
PL101951B1 (pl) 1979-02-28
FI61875B (fi) 1982-06-30
SU635867A3 (ru) 1978-11-30
CA1076142A (en) 1980-04-22
DE2610886A1 (de) 1976-10-07
SE7603341L (sv) 1976-09-21
YU71476A (en) 1982-10-31
US4085225A (en) 1978-04-18
IL49238A0 (en) 1976-05-31

Similar Documents

Publication Publication Date Title
IL49238A (en) O-aminoethyl trifluoromethyl-phenyl-ketoximes, their preparation and pharmaceutical compositions containing them
IL50632A (en) Pyridinyl-2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
IL50176A0 (en) Novel tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL48835A0 (en) New peptides,their preparation and pharmaceutical compositions containing them
IL50815A0 (en) New aminobenzoamides their preparation and pharmaceutical compositions containing them
IL49911A0 (en) New 5-aroylpyrrole derivatives,their preparation and pharmaceutical compositions containing them
IL50047A0 (en) Novel peptides,their preparation and pharmaceutical compositions containing them
IL50631A0 (en) 1-benzazolylalkyl-4-substituted-piperidines,their preparation and pharmaceutical compositions containing them
IL50690A0 (en) Novel benzisothiazole derivatives,their preparation and pharmaceutical compositions containing them
IL50869A (en) Heterocyclylthio-ethylimidazole derivatives,their preparation and pharmaceutical compositions containing them
IL49424A0 (en) 1,1,1-triaryl-alkylamines,their preparation and pharmaceutical compositions containing them
IL49788A0 (en) 11-desoxy-16-aryloxy-omega-pentanorprostaglandins,their preparation and pharmaceutical compositions containing them
IL49280A0 (en) Novel benzophenones,their preparation and pharmaceutical compositions containing them
IL50335A (en) Diphenylalkylpolyamine derivatives,their preparation and pharmaceutical compositions containing them
IL49991A0 (en) L-pyroglutamyl-l-prolinamide,its preparation and pharmaceutical compositions containing it
IL49132A (en) 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them
IL50156A (en) N,n-bis-isoquinolinoalkylamine derivatives, their preparation and pharmaceutical compositions containing them
IL50797A0 (en) New penicillins,their preparation and pharmaceutical compositions containing them
IL49099A (en) Xanthene-9-carboxylates, their preparation and pharmaceutical compositions containing them
IL49971A0 (en) New 2-benzoypranone derivatives,their preparation and pharmaceutical compositions containing them
IL48788A0 (en) New penicillins,their preparation and pharmaceutical compositions containing them
IL50554A (en) 2,9-dioxatricyclodecanes,their preparation and pharmaceutical compositions containing them
IL49847A0 (en) New penicillins,their preparation and pharmaceutical compositions containing them
IL49239A (en) O-aminoethyl methylthiophenyl-ketoximes, their preparation and pharmaceutical compositions containing them
IL50090A0 (en) New quinolines,their preparation and pharmaceutical compositions containing them