CH615677A5 - - Google Patents
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- Publication number
- CH615677A5 CH615677A5 CH393179A CH393179A CH615677A5 CH 615677 A5 CH615677 A5 CH 615677A5 CH 393179 A CH393179 A CH 393179A CH 393179 A CH393179 A CH 393179A CH 615677 A5 CH615677 A5 CH 615677A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- acid
- formula
- tetrahydrofurfuryl
- formula iii
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2437610A DE2437610A1 (de) | 1974-08-05 | 1974-08-05 | Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
CH615677A5 true CH615677A5 (ro) | 1980-02-15 |
Family
ID=5922448
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1002475A CH613963A5 (ro) | 1974-08-05 | 1975-07-31 | |
CH393379A CH616420A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393579A CH616421A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393679A CH615680A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393479A CH615679A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393279A CH615678A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393179A CH615677A5 (ro) | 1974-08-05 | 1979-04-26 |
Family Applications Before (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1002475A CH613963A5 (ro) | 1974-08-05 | 1975-07-31 | |
CH393379A CH616420A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393579A CH616421A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393679A CH615680A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393479A CH615679A5 (ro) | 1974-08-05 | 1979-04-26 | |
CH393279A CH615678A5 (ro) | 1974-08-05 | 1979-04-26 |
Country Status (27)
Country | Link |
---|---|
US (1) | US3982005A (ro) |
JP (1) | JPS60358B2 (ro) |
AT (1) | AT348140B (ro) |
BE (1) | BE832099R (ro) |
BG (3) | BG25089A3 (ro) |
CA (1) | CA1049008A (ro) |
CH (7) | CH613963A5 (ro) |
CS (1) | CS189717B2 (ro) |
DD (1) | DD122685A5 (ro) |
DE (1) | DE2437610A1 (ro) |
DK (1) | DK138992C (ro) |
ES (6) | ES452768A1 (ro) |
FI (1) | FI63229C (ro) |
FR (1) | FR2320096A2 (ro) |
GB (1) | GB1513950A (ro) |
HU (1) | HU177952B (ro) |
IE (1) | IE42216B1 (ro) |
IL (1) | IL47860A (ro) |
LU (1) | LU73138A1 (ro) |
NL (1) | NL7509249A (ro) |
NO (1) | NO143460C (ro) |
PH (1) | PH13687A (ro) |
PL (3) | PL99838B1 (ro) |
RO (3) | RO67390A (ro) |
SE (1) | SE425392B (ro) |
SU (3) | SU591147A3 (ro) |
ZA (1) | ZA754997B (ro) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
GB1575009A (en) * | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
DE2716687A1 (de) * | 1977-04-15 | 1978-10-19 | Boehringer Sohn Ingelheim | 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel |
NL7804509A (nl) * | 1978-04-26 | 1979-10-30 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. |
DE2828039A1 (de) * | 1978-06-26 | 1980-01-10 | Boehringer Sohn Ingelheim | 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung |
JPS5636521A (en) * | 1979-08-31 | 1981-04-09 | Shin Etsu Chem Co Ltd | Production of alkenyloxy group-containing organopolysiloxane |
ES2395081T3 (es) | 2007-07-26 | 2013-02-08 | Vitae Pharmaceuticals, Inc. | Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1 |
EP2220048B1 (en) | 2007-11-16 | 2017-01-25 | Boehringer Ingelheim International GmbH | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
CA2712500A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
WO2009102460A2 (en) | 2008-02-15 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8569292B2 (en) | 2008-05-01 | 2013-10-29 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
JP5538365B2 (ja) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤 |
EP2300461B1 (en) | 2008-05-01 | 2013-04-17 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
RU2539979C2 (ru) | 2008-07-25 | 2015-01-27 | Вайтаи Фармасьютиклз, Инк. | Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1 |
JP5777030B2 (ja) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
EP2440537A1 (en) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜芳基羰基衍生物 |
WO2011159760A1 (en) | 2010-06-16 | 2011-12-22 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
EP2744783A1 (en) | 2011-08-17 | 2014-06-25 | Boehringer Ingelheim International GmbH | Indenopyridine derivatives |
US20240002606A1 (en) | 2020-11-26 | 2024-01-04 | Shin-Etsu Chemical Co., Ltd. | Room temperature curable organopolysiloxane composition, article, hydrolyzable organosilane compound and method for producing same |
KR20240052040A (ko) | 2021-09-03 | 2024-04-22 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 오르가노폴리실록산 화합물, 실온 경화성 오르가노폴리실록산 조성물 및 물품 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE582575A (ro) * | 1958-09-22 | |||
US3700734A (en) * | 1969-01-23 | 1972-10-24 | Merck & Co Inc | 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan |
DE2105743C3 (de) * | 1971-02-08 | 1979-11-29 | Boehringer Sohn Ingelheim | 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung |
CS166804B2 (ro) * | 1971-02-08 | 1976-03-29 | Boehringer Sohn Ingelheim | |
DE2200596A1 (de) * | 1972-01-07 | 1973-07-12 | Boehringer Sohn Ingelheim | N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
DE2217420C3 (de) * | 1972-04-12 | 1981-03-12 | C.H. Boehringer Sohn, 6507 Ingelheim | N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen |
DE2229695A1 (de) * | 1972-06-19 | 1974-01-31 | Boehringer Sohn Ingelheim | 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
-
1974
- 1974-08-05 DE DE2437610A patent/DE2437610A1/de not_active Ceased
-
1975
- 1975-07-08 AT AT523775A patent/AT348140B/de not_active IP Right Cessation
- 1975-07-25 SU SU752162235A patent/SU591147A3/ru active
- 1975-07-30 US US05/600,374 patent/US3982005A/en not_active Expired - Lifetime
- 1975-07-30 RO RO7583017A patent/RO67390A/ro unknown
- 1975-07-30 JP JP50092995A patent/JPS60358B2/ja not_active Expired
- 1975-07-31 RO RO7593231A patent/RO72736A/ro unknown
- 1975-07-31 RO RO7593232A patent/RO72735A/ro unknown
- 1975-07-31 CH CH1002475A patent/CH613963A5/xx not_active IP Right Cessation
- 1975-08-01 CA CA75232728A patent/CA1049008A/en not_active Expired
- 1975-08-02 BG BG7500031842A patent/BG25089A3/xx unknown
- 1975-08-02 BG BG7500031843A patent/BG25090A3/xx unknown
- 1975-08-02 BG BG7500030726A patent/BG25088A3/xx unknown
- 1975-08-04 BE BE158924A patent/BE832099R/xx not_active IP Right Cessation
- 1975-08-04 FI FI752211A patent/FI63229C/fi not_active IP Right Cessation
- 1975-08-04 PL PL1975182528A patent/PL99838B1/pl unknown
- 1975-08-04 PH PH17443A patent/PH13687A/en unknown
- 1975-08-04 ZA ZA754997A patent/ZA754997B/xx unknown
- 1975-08-04 IL IL47860A patent/IL47860A/xx unknown
- 1975-08-04 DK DK352875A patent/DK138992C/da active
- 1975-08-04 NO NO752731A patent/NO143460C/no unknown
- 1975-08-04 DD DD187666A patent/DD122685A5/xx unknown
- 1975-08-04 SE SE7508789A patent/SE425392B/xx not_active IP Right Cessation
- 1975-08-04 NL NL7509249A patent/NL7509249A/xx not_active Application Discontinuation
- 1975-08-04 HU HU75BO1566A patent/HU177952B/hu unknown
- 1975-08-04 PL PL1975190658A patent/PL99819B1/pl unknown
- 1975-08-04 CS CS755425A patent/CS189717B2/cs unknown
- 1975-08-04 GB GB32576/75A patent/GB1513950A/en not_active Expired
- 1975-08-04 LU LU73138A patent/LU73138A1/xx unknown
- 1975-08-04 PL PL1975190659A patent/PL99816B1/pl unknown
- 1975-08-05 FR FR7524380A patent/FR2320096A2/fr active Granted
- 1975-08-05 IE IE1738/75A patent/IE42216B1/en unknown
-
1976
- 1976-04-16 SU SU762346108A patent/SU587859A3/ru active
- 1976-04-16 SU SU762346107A patent/SU587858A3/ru active
- 1976-10-27 ES ES452768A patent/ES452768A1/es not_active Expired
- 1976-10-27 ES ES452764A patent/ES452764A1/es not_active Expired
- 1976-10-27 ES ES452767A patent/ES452767A1/es not_active Expired
- 1976-10-27 ES ES452765A patent/ES452765A1/es not_active Expired
- 1976-10-27 ES ES452763A patent/ES452763A1/es not_active Expired
- 1976-10-27 ES ES452766A patent/ES452766A1/es not_active Expired
-
1979
- 1979-04-26 CH CH393379A patent/CH616420A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393579A patent/CH616421A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393679A patent/CH615680A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393479A patent/CH615679A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393279A patent/CH615678A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393179A patent/CH615677A5/de not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |