CA2949772A1 - Binding molecules to the human ox40 receptor - Google Patents

Binding molecules to the human ox40 receptor Download PDF

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Publication number
CA2949772A1
CA2949772A1 CA2949772A CA2949772A CA2949772A1 CA 2949772 A1 CA2949772 A1 CA 2949772A1 CA 2949772 A CA2949772 A CA 2949772A CA 2949772 A CA2949772 A CA 2949772A CA 2949772 A1 CA2949772 A1 CA 2949772A1
Authority
CA
Canada
Prior art keywords
amino acid
antibody
human
seq
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2949772A
Other languages
English (en)
French (fr)
Inventor
Jing Min
Yanli Wu
Rory Francis Finn
Barrett Richard Thiele
Wei Liao
Ronald Paul Gladue
Arvind Rajpal
Timothy Joseph Paradis
Peter Brams
Brigitte Devaux
Yi Wu
Kristopher Toy
Heidi N. Leblanc
Haichum Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Pfizer Inc
Original Assignee
Bristol Myers Squibb Co
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40552119&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2949772(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co, Pfizer Inc filed Critical Bristol Myers Squibb Co
Publication of CA2949772A1 publication Critical patent/CA2949772A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2949772A 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor Abandoned CA2949772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1394707P 2007-12-14 2007-12-14
US61/013,947 2007-12-14
CA2707773A CA2707773C (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2707773A Division CA2707773C (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor

Publications (1)

Publication Number Publication Date
CA2949772A1 true CA2949772A1 (en) 2009-06-25

Family

ID=40552119

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2949772A Abandoned CA2949772A1 (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor
CA2707773A Active CA2707773C (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2707773A Active CA2707773C (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor

Country Status (29)

Country Link
US (7) US7960515B2 (enExample)
EP (4) EP2594590B1 (enExample)
JP (4) JP5761997B2 (enExample)
KR (2) KR20150061041A (enExample)
CN (1) CN101918447B (enExample)
AR (2) AR069681A1 (enExample)
AU (1) AU2008338591B8 (enExample)
BR (1) BRPI0820875B1 (enExample)
CA (2) CA2949772A1 (enExample)
CL (1) CL2008003706A1 (enExample)
CO (1) CO6280541A2 (enExample)
DK (3) DK2594590T3 (enExample)
ES (3) ES2526887T3 (enExample)
HR (1) HRP20141188T8 (enExample)
HU (1) HUE032735T2 (enExample)
IL (3) IL206297A (enExample)
MX (1) MX2010006466A (enExample)
PA (1) PA8807601A1 (enExample)
PE (1) PE20091269A1 (enExample)
PH (1) PH12015500806B1 (enExample)
PL (2) PL2242771T3 (enExample)
PT (3) PT2851374T (enExample)
RU (1) RU2010129045A (enExample)
SG (2) SG10201604770VA (enExample)
SI (3) SI2242771T1 (enExample)
TW (1) TW200932268A (enExample)
UY (1) UY31533A1 (enExample)
WO (1) WO2009079335A1 (enExample)
ZA (1) ZA201003579B (enExample)

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