CA2899926C - DIGESTIVE TUBE FILLING COMPOSITIONS - Google Patents

DIGESTIVE TUBE FILLING COMPOSITIONS

Info

Publication number
CA2899926C
CA2899926C CA2899926A CA2899926A CA2899926C CA 2899926 C CA2899926 C CA 2899926C CA 2899926 A CA2899926 A CA 2899926A CA 2899926 A CA2899926 A CA 2899926A CA 2899926 C CA2899926 C CA 2899926C
Authority
CA
Canada
Prior art keywords
therapeutic composition
spore
population
bacterial
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2899926A
Other languages
English (en)
French (fr)
Other versions
CA2899926A1 (en
Inventor
Gregory McKenzie
Mary-Jane Lombardo McKenzie
David Cook
Marin Vulic
Geoffrey von Maltzahn
Brian Goodman
John G. Aunins
Matthew R. Henn
David A. Berry
Jonathan Winkler
Original Assignee
Seres Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seres Therapeutics Inc filed Critical Seres Therapeutics Inc
Publication of CA2899926A1 publication Critical patent/CA2899926A1/en
Application granted granted Critical
Publication of CA2899926C publication Critical patent/CA2899926C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2899926A 2013-02-04 2014-02-04 DIGESTIVE TUBE FILLING COMPOSITIONS Active CA2899926C (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361760584P 2013-02-04 2013-02-04
US201361760574P 2013-02-04 2013-02-04
US201361760606P 2013-02-04 2013-02-04
US201361760585P 2013-02-04 2013-02-04
US61/760,574 2013-02-04
US61/760,584 2013-02-04
US61/760,585 2013-02-04
US61/760,606 2013-02-04
US201461926918P 2014-01-13 2014-01-13
US61/926,918 2014-01-13
PCT/US2014/014745 WO2014121302A2 (en) 2013-02-04 2014-02-04 Compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3280244A Division CA3280244A1 (en) 2013-02-04 2014-02-04 Compositions for populating a gastrointestinal tract

Publications (2)

Publication Number Publication Date
CA2899926A1 CA2899926A1 (en) 2014-08-07
CA2899926C true CA2899926C (en) 2025-11-18

Family

ID=51263061

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2899926A Active CA2899926C (en) 2013-02-04 2014-02-04 DIGESTIVE TUBE FILLING COMPOSITIONS
CA2899925A Pending CA2899925A1 (en) 2013-02-04 2014-02-04 Compositions and methods for inhibition of pathogenic bacterial growth

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2899925A Pending CA2899925A1 (en) 2013-02-04 2014-02-04 Compositions and methods for inhibition of pathogenic bacterial growth

Country Status (13)

Country Link
US (14) US11185562B2 (enExample)
EP (5) EP3587558A3 (enExample)
JP (6) JP2016509003A (enExample)
KR (3) KR102553134B1 (enExample)
CN (2) CN110917220A (enExample)
AU (7) AU2014212004B2 (enExample)
BR (2) BR112015018625A2 (enExample)
CA (2) CA2899926C (enExample)
HK (3) HK1219022A1 (enExample)
MX (2) MX369877B (enExample)
NZ (1) NZ711771A (enExample)
RU (1) RU2664479C2 (enExample)
WO (3) WO2014121301A1 (enExample)

Families Citing this family (359)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
US9585920B2 (en) 2011-02-04 2017-03-07 Katherine Rose Kovarik Method and system for treating cancer cachexia
US9457077B2 (en) 2009-11-18 2016-10-04 Katherine Rose Kovarik Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases
RS63299B1 (sr) 2010-02-01 2022-07-29 Rebiotix Inc Bakterioterapija clostridium difficile kolitisa
WO2011103274A1 (en) * 2010-02-17 2011-08-25 Gen-Probe Incorporated Compositions and methods to detect atopobium vaginae nucleic acid
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
NZ607043A (en) 2010-08-04 2015-05-29 Borody Thomas J Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US10314865B2 (en) 2011-02-04 2019-06-11 Katherine Rose Kovarik Method and system for treating cancer and other age-related diseases by extending the healthspan of a human
US10111913B2 (en) 2011-02-04 2018-10-30 Joseph E. Kovarik Method of reducing the likelihood of skin cancer in an individual human being
US9730967B2 (en) 2011-02-04 2017-08-15 Katherine Rose Kovarik Method and system for treating cancer cachexia
US10842834B2 (en) 2016-01-06 2020-11-24 Joseph E. Kovarik Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease
US10085938B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for preventing sore throat in humans
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11419903B2 (en) 2015-11-30 2022-08-23 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
US11191665B2 (en) 2011-02-04 2021-12-07 Joseph E. Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US10548761B2 (en) 2011-02-04 2020-02-04 Joseph E. Kovarik Method and system for reducing the likelihood of colorectal cancer in a human being
US10512661B2 (en) 2011-02-04 2019-12-24 Joseph E. Kovarik Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US10583033B2 (en) 2011-02-04 2020-03-10 Katherine Rose Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US10835560B2 (en) 2013-12-20 2020-11-17 Joseph E. Kovarik Reducing the likelihood of skin cancer in an individual human being
US12533312B2 (en) 2011-02-04 2026-01-27 Seed Health, Inc. Method and system for preventing sore throat in humans
US10245288B2 (en) 2011-02-04 2019-04-02 Joseph E. Kovarik Method and system for reducing the likelihood of developing NASH in an individual diagnosed with non-alcoholic fatty liver disease
US10086018B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for reducing the likelihood of colorectal cancer in a human being
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US10010568B2 (en) 2011-02-04 2018-07-03 Katherine Rose Kovarik Method and system for reducing the likelihood of a spirochetes infection in a human being
US11523934B2 (en) 2011-02-04 2022-12-13 Seed Health, Inc. Method and system to facilitate the growth of desired bacteria in a human's mouth
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11273187B2 (en) 2015-11-30 2022-03-15 Joseph E. Kovarik Method and system for reducing the likelihood of developing depression in an individual
US10940169B2 (en) 2015-11-30 2021-03-09 Joseph E. Kovarik Method for reducing the likelihood of developing cancer in an individual human being
US10687975B2 (en) 2011-02-04 2020-06-23 Joseph E. Kovarik Method and system to facilitate the growth of desired bacteria in a human's mouth
US9987224B2 (en) 2011-02-04 2018-06-05 Joseph E. Kovarik Method and system for preventing migraine headaches, cluster headaches and dizziness
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
CA2829385C (en) 2011-03-09 2021-07-13 Michael J. Sadowsky Compositions and methods for transplantation of colon microbiota
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
EP3569690B1 (en) 2011-12-01 2024-08-28 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
WO2013130773A2 (en) 2012-02-29 2013-09-06 Ethicon Endo-Surgery, Inc. Compositions of microbiota and methods related thereto
EP3692999A1 (en) * 2012-03-17 2020-08-12 The Regents of the University of California Fast diagnosis and personalized treatments for acne
WO2013139861A1 (en) 2012-03-20 2013-09-26 Luc Montagnier Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
JP6203816B2 (ja) 2012-03-29 2017-09-27 セラバイオーム,エルエルシー 回腸及び虫垂に対して活性の胃腸部位特異的経口ワクチン接種製剤
WO2013176774A1 (en) 2012-05-25 2013-11-28 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
CA2875369C (en) 2012-06-04 2017-11-21 Suncor Energy Inc. Formulations containing paraffinic oil and anti-settling agent
CN114949001A (zh) 2012-08-29 2022-08-30 加州理工学院 孤独症谱系障碍的诊断和治疗
DK3628161T3 (da) 2012-11-23 2023-05-30 Seres Therapeutics Inc Synergistiske bakterielle sammensætninger og fremgangsmåder til fremstilling og anvendelse deraf
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
WO2014121304A1 (en) 2013-02-04 2014-08-07 Seres Health, Inc. Compositions and methods
AU2014212004B2 (en) 2013-02-04 2018-09-20 Société des Produits Nestlé S.A. Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases
RU2015140610A (ru) 2013-03-14 2017-04-17 ТЕРАБАЙОМ, ЭлЭлСи Направленная доставка в желудочно-кишечный тракт пробиотических микроорганизмов и/или терапевтических средств
CA2877585C (en) 2013-03-15 2016-04-12 Suncor Energy Inc. Herbicidal compositions
EP2967077A4 (en) 2013-03-15 2016-09-14 Seres Therapeutics Inc NETWORK-BASED MICROBIAL COMPOSITIONS AND METHOD
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
JP6330032B2 (ja) 2013-06-05 2018-05-23 レビオティクス インコーポレイテッドRebiotix,Inc. 微生物叢回復療法組成物を製造、処理、および梱包するための方法
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US11274144B2 (en) 2013-06-13 2022-03-15 Research Institute At Nationwide Children's Hospital Compositions and methods for the removal of biofilms
US10633714B2 (en) 2013-07-21 2020-04-28 Pendulum Therapeutics, Inc. Methods and systems for microbiome characterization, monitoring and treatment
KR102611070B1 (ko) 2013-11-25 2023-12-07 세레스 테라퓨틱스, 인코포레이티드 상승적 박테리아 조성물 및 그것의 생산 방법 및 용도
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US12318377B2 (en) 2013-12-20 2025-06-03 Seed Health, Inc. Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11672835B2 (en) 2013-12-20 2023-06-13 Seed Health, Inc. Method for treating individuals having cancer and who are receiving cancer immunotherapy
US11529379B2 (en) 2013-12-20 2022-12-20 Seed Health, Inc. Method and system for reducing the likelihood of developing colorectal cancer in an individual human being
US11026982B2 (en) 2015-11-30 2021-06-08 Joseph E. Kovarik Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being
US11642382B2 (en) 2013-12-20 2023-05-09 Seed Health, Inc. Method for treating an individual suffering from bladder cancer
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11213552B2 (en) 2015-11-30 2022-01-04 Joseph E. Kovarik Method for treating an individual suffering from a chronic infectious disease and cancer
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
CA2941694A1 (en) 2014-03-06 2015-09-11 Research Institute At Nationwide Children's Hospital Probiotic formulations and methods for use
US10624934B2 (en) 2014-03-06 2020-04-21 Research Institute At Nationwide Children's Hospital Prebiotic formulations
US9783858B2 (en) * 2014-04-02 2017-10-10 Northwestern University Altered microbiome of chronic pelvic pain
US10766799B2 (en) 2014-05-23 2020-09-08 Nch Corporation Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method
FI127671B (en) 2014-05-28 2018-11-30 Filip Scheperjans Method for diagnostics of Parkinson’s disease
US20160016002A1 (en) * 2014-07-17 2016-01-21 John Todd Kuenstner Treatment of Diseases Using Combination of Ultraviolet Blood Irradiation and Probiotics
CN106659799B (zh) * 2014-07-25 2020-07-17 碧奥辛斯有限责任公司 用于制备针对因肠致病性细菌引起的感染的广谱疫苗的包含表达内置的多个表位的分子构建体的基本单元的糖缀合物疫苗
EP3194566B1 (en) * 2014-08-04 2019-03-27 Basf Se Antifungal paenibacillus strains, fusaricidin-type compounds, and their use
US10286016B2 (en) 2014-09-02 2019-05-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating gonorrhea
US10900043B2 (en) 2014-09-02 2021-01-26 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating bacterial disease
CA2959414C (en) 2014-09-05 2023-03-14 Symbiomix Therapeutics, Llc Secnidazole for use in the treatment of bacterial vaginosis
WO2016057671A1 (en) * 2014-10-07 2016-04-14 University Of Virginia Patent Foundation Compositions and methods for preventing and treating infection
US10325685B2 (en) 2014-10-21 2019-06-18 uBiome, Inc. Method and system for characterizing diet-related conditions
US9758839B2 (en) 2014-10-21 2017-09-12 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features
US10311973B2 (en) 2014-10-21 2019-06-04 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
US9760676B2 (en) 2014-10-21 2017-09-12 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions
US10777320B2 (en) 2014-10-21 2020-09-15 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for mental health associated conditions
US10265009B2 (en) 2014-10-21 2019-04-23 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features
US10793907B2 (en) 2014-10-21 2020-10-06 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions
US10346592B2 (en) 2014-10-21 2019-07-09 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
US10357157B2 (en) 2014-10-21 2019-07-23 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features
US9754080B2 (en) 2014-10-21 2017-09-05 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for cardiovascular disease conditions
US10409955B2 (en) 2014-10-21 2019-09-10 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions
US10169541B2 (en) 2014-10-21 2019-01-01 uBiome, Inc. Method and systems for characterizing skin related conditions
US9703929B2 (en) 2014-10-21 2017-07-11 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics
US10073952B2 (en) 2014-10-21 2018-09-11 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
US9710606B2 (en) 2014-10-21 2017-07-18 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
US10410749B2 (en) 2014-10-21 2019-09-10 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions
US10395777B2 (en) 2014-10-21 2019-08-27 uBiome, Inc. Method and system for characterizing microorganism-associated sleep-related conditions
EA201790811A1 (ru) 2014-10-30 2017-11-30 Калифорния Инститьют Оф Текнолоджи Содержащие бактерии композиции и способы для улучшения видов поведения при нарушениях неврологического развития
WO2016069801A1 (en) * 2014-10-30 2016-05-06 California Institute Of Technology Compositions and methods comprising bacteria for improving behavior in neurodecelopmental disorders
EP4529950A3 (en) 2014-10-31 2025-08-20 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
EP3223835B1 (en) * 2014-11-25 2024-11-13 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
MA41020A (fr) * 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
WO2016103005A1 (en) 2014-12-23 2016-06-30 Institut Pasteur Method of culturing segmented filamentous bacteria in vitro
PL3193901T3 (pl) 2014-12-23 2018-10-31 4D Pharma Research Limited Polipeptyd pyrynowy i immunomodulacja
WO2016105498A1 (en) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
CN113862175A (zh) 2014-12-23 2021-12-31 4D制药研究有限公司 免疫调控
EP3253396A4 (en) * 2015-02-06 2018-08-29 Western University Of Health Sciences Probiotic compositions and methods of use
US10709773B2 (en) 2015-03-06 2020-07-14 Synthetic Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
AU2016228888A1 (en) * 2015-03-12 2017-10-26 The University Of British Columbia Bacterial compositions and methods of use thereof
CN107404901B (zh) * 2015-03-16 2021-10-08 洛桑联邦理工学院 生物活性动物饲料中的古细菌,制造组合物的方法和使用该组合物的方法
EP3277847A4 (en) 2015-04-03 2018-12-05 Quest Diagnostics Investments Incorporated Assay for detection of pathogenic leptospira strains
WO2016168352A1 (en) * 2015-04-13 2016-10-20 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features
WO2016168350A1 (en) * 2015-04-13 2016-10-20 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions
US10246753B2 (en) 2015-04-13 2019-04-02 uBiome, Inc. Method and system for characterizing mouth-associated conditions
CN107708715B (zh) * 2015-04-13 2022-06-03 普梭梅根公司 用于微生物组功能特征相关的状况的微生物组来源的诊断和治疗的方法及系统
EP3283087A4 (en) * 2015-04-14 2019-03-13 Ubiome Inc. METHOD AND SYSTEM FOR MICROBIOMEDIVED DIAGNOSTICS AND THERAPEUTICS FOR DISEASES OF THE ENDOCRINE SYSTEM
US12050161B2 (en) 2015-04-24 2024-07-30 Maat Pharma Microorganism sampling method, microorganism sampling device and sampling kit comprising such a sampling device
FR3035317B1 (fr) 2015-04-24 2019-06-14 Maat Pharma Dispositif de prelevement de micro-organismes, kit de prelevement comprenant un tel dispositif et procede de prelevement mettant en œuvre un tel dispositif
FR3035328B1 (fr) 2015-04-24 2019-08-23 Maat Pharma Procede de preparation d'un echantillon de microbiote fecal
BR112017024264B1 (pt) * 2015-05-14 2022-07-12 Crestovo Holdings Llc Composições para transplante de flora fecal e métodos de preparação e utilização das mesmas, e dispositivos para sua administração
PT3297644T (pt) * 2015-05-22 2022-03-30 Univ Arizona State Métodos para tratar distúrbios do espetro do autismo e sintomas associados
WO2016196653A1 (en) 2015-06-01 2016-12-08 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
CN105067731B (zh) * 2015-06-05 2017-06-16 中国农业科学院兰州兽医研究所 一种弓形虫感染后血清中生物标记物的筛选方法及筛选出的生物标记物的应用
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
CN107921072A (zh) 2015-06-09 2018-04-17 雷柏奥提斯有限公司 微生物群恢复治疗(mrt)组合物和制造方法
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
RS59446B1 (sr) * 2015-06-15 2019-11-29 4D Pharma Res Ltd Blautia stercosis i wexlerae za upotrebu u lečenju inflamatornih i autoimunskih bolesti
MD3206700T2 (ro) 2015-06-15 2019-12-31 4D Pharma Res Ltd Compoziții conținând tulpini bacteriene
PE20180267A1 (es) 2015-06-15 2018-02-06 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US10632157B2 (en) 2016-04-15 2020-04-28 Ascus Biosciences, Inc. Microbial compositions and methods of use for improving fowl production
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
ES2978111T3 (es) 2015-06-25 2024-09-05 Native Microbials Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e identificar relaciones funcionales e interacciones de las mismas, y seleccionar y sintetizar conjuntos microbianos basados en las mismas
CN108348558A (zh) * 2015-07-08 2018-07-31 赛里斯治疗公司 治疗结肠炎的方法
AU2016303688B2 (en) 2015-07-31 2023-06-15 Research Institute At Nationwide Children's Hospital Peptides and antibodies for the removal of biofilms
CN108289917A (zh) * 2015-08-24 2018-07-17 努比约塔有限公司 使用粪源细菌群落来治疗微生态失衡的系统和方法
EP4242328A3 (en) * 2015-09-04 2024-02-21 Memorial Sloan-Kettering Cancer Center Methods for detecting risk of cancer relapse using eubacterium limosum
CA3006044A1 (en) * 2015-09-09 2017-03-16 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health
WO2017053544A1 (en) * 2015-09-22 2017-03-30 Mayo Foundation For Medical Education And Research Methods and materials for using biomarkers which predict susceptibility to clostridium difficile infection
BR112018005863B1 (pt) 2015-09-24 2024-02-27 Agriculture Victoria Services Pty Ltd Método para isolamento, seleção e/ou caracterização de uma linhagem endofítica
MX387286B (es) 2015-09-29 2025-03-18 Kimberly Clark Co Composicion sinergica para el mantenimiento de un equilibrio saludable de la microflora.
WO2017066719A2 (en) 2015-10-14 2017-04-20 Research Institute At Nationwide Children's Hospital Hu specific interfering agents
EP3370748B1 (en) 2015-11-03 2022-06-08 The Brigham and Women's Hospital, Inc. Therapeutic microbiota for the treatment and/or prevention of food allergy
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017085520A1 (en) 2015-11-20 2017-05-26 4D Pharma Research Limited Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
ES2938361T3 (es) * 2015-11-24 2023-04-10 Seres Therapeutics Inc Composiciones de bacterias diseñadas
US10568916B2 (en) 2015-11-30 2020-02-25 Joseph E. Kovarik Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides
US11529412B2 (en) 2015-11-30 2022-12-20 Seed Health, Inc. Method and system for protecting honey bees from pesticides
US12239706B2 (en) 2015-11-30 2025-03-04 Seed Health, Inc. Method and system for protecting monarch butterflies from pesticides
US10086024B2 (en) 2015-11-30 2018-10-02 Joseph E. Kovarik Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides
US10933128B2 (en) 2015-11-30 2021-03-02 Joseph E. Kovarik Method and system for protecting honey bees from pesticides
US10675347B2 (en) 2015-11-30 2020-06-09 Joseph E. Kovarik Method and system for protecting honey bees from fipronil pesticides
WO2017100420A1 (en) * 2015-12-08 2017-06-15 Mayo Foundation For Medical Education And Research Biomarkers for predicting clostridium difficile infection treatment outcome
FR3045383B1 (fr) * 2015-12-18 2019-06-14 Maat Pharma Procede de lyophilisation d'un echantillon de microbiote fecal
CN109757107A (zh) 2016-01-07 2019-05-14 埃斯库斯生物科技股份公司 用于通过施用微生物聚生体来提高乳产量的方法
CN106974940B (zh) * 2016-01-15 2020-08-25 深圳华大生命科学研究院 厚壁菌类益生菌在治疗和预防肥胖及其相关疾病中的应用
IL243707A0 (en) 2016-01-20 2016-05-01 Galmed Res And Dev Ltd Treatment to regulate the microbiota in the intestine
SMT202000547T1 (it) * 2016-02-04 2020-11-10 Univ Gent Uso di comunita' microbiche per la salute umana e animale
WO2017137834A1 (en) * 2016-02-08 2017-08-17 University Of Oslo Bacterial growth media
EP3205209A1 (en) 2016-02-09 2017-08-16 Basf Se Mixtures and compositions comprising paenibacillus strains or metabolites thereof and other biopesticides
JP6441536B2 (ja) 2016-03-04 2018-12-19 フォーディー ファーマ ピーエルシー4D Pharma Plc 細菌株を含む組成物
EP3423093A4 (en) 2016-03-04 2019-11-13 The Regents of The University of California MICROBIAL CONSORTIUM AND USES THEREOF
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
CA3016911A1 (en) 2016-03-14 2017-09-21 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
SG11201808246SA (en) * 2016-03-24 2018-10-30 Paratek Pharm Innc Methods for treating and preventing c. difficile infection
US10897922B2 (en) 2016-04-05 2021-01-26 Nch Corporation Composition and method for germinative compounds in probiotic food and beverage products for human consumption
MY190858A (en) 2016-04-05 2022-05-12 Nch Corp Nutrient rich germinant composition and spore incubation method
US12097226B2 (en) 2016-04-05 2024-09-24 Nch Corporation System and method for using a single-serve nutrient spore composition for small scale farm applications
US10617134B2 (en) 2016-04-15 2020-04-14 Ascus Biosciences, Inc. Methods for improving agricultural production of fowl by administration of microbial compositions or purified strains thereof
ES2987655T7 (en) * 2016-04-19 2025-04-29 Genome Res Ltd Bacteriotherapy
KR20190017751A (ko) 2016-04-21 2019-02-20 네이키드 바이옴, 인크. 피부 장애의 치료를 위한 조성물 및 방법
US10252145B2 (en) 2016-05-02 2019-04-09 Bao Tran Smart device
JP7655693B2 (ja) 2016-05-23 2025-04-02 カリフォルニア インスティチュート オブ テクノロジー 神経変性障害を治療するための腸内微生物叢の制御
US20170348360A1 (en) * 2016-06-01 2017-12-07 Crestovo Llc Compositions and Methods for Treating Inflammatory Bowel Diseases (IBDs) and Other Disorders
KR20250140643A (ko) * 2016-06-14 2025-09-25 베단타 바이오사이언시즈, 인크. 클로스트리디움 디피실레 감염의 치료
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
US20170360848A1 (en) 2016-06-15 2017-12-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods for treating autism spectrum disorder and associated symptoms
WO2017218889A1 (en) * 2016-06-16 2017-12-21 Ohio State Innovation Foundation Eubacterium probiotics and methods of treating or preventing heart disease
US10849936B2 (en) 2016-07-01 2020-12-01 Regents Of The University Of Minnesota Compositions and methods for C. difficile treatment
GB201703552D0 (en) * 2017-03-06 2017-04-19 4D Pharma Plc Compositions comprising bacterial strains
WO2018013865A1 (en) * 2016-07-13 2018-01-18 uBiome, Inc. Method and system for microbial pharmacogenomics
TW201821093A (zh) 2016-07-13 2018-06-16 英商4D製藥有限公司 包含細菌菌株之組合物
GB201703548D0 (en) * 2017-03-06 2017-04-19 4D Pharma Plc Compositions comprising bacterial strains
KR101815692B1 (ko) * 2016-07-25 2018-01-16 주식회사 고바이오랩 구강 세균의 군집을 이용한 대사성 질환 진단용 바이오 마커
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
WO2018031545A1 (en) * 2016-08-11 2018-02-15 The Trustees Of The University Of Pennsylvania Compositions and methods for detecting oral squamous cell carcinomas
WO2018046485A1 (en) 2016-09-09 2018-03-15 Swecure Ab Use of butyricimonas and/or oxalobacter for treating irritable bowel syndrome
WO2018071537A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
US10092601B2 (en) 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
WO2018071536A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating primary sclerosing cholangitis and related disorders
JP6927512B2 (ja) * 2016-10-26 2021-09-01 地方独立行政法人神奈川県立産業技術総合研究所 物体表面の抗菌性試験用菌液媒体
WO2018106844A1 (en) * 2016-12-06 2018-06-14 Whole Biome Inc. Methods and compositions relating to isolated and purified microbes
GB201621123D0 (en) * 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
CA3048669A1 (en) 2016-12-15 2018-06-21 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating growth of a genetically modified gut bacterial cell
WO2018112371A1 (en) * 2016-12-16 2018-06-21 Vedanta Biosciences, Inc. Methods and compositions for determining bacterial integrity
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
IL296740B2 (en) * 2016-12-23 2023-09-01 Univ Keio Compositions and methods for the induction of cd8+ t-cells
JP2020503048A (ja) 2016-12-28 2020-01-30 アスカス バイオサイエンシーズ, インコーポレイテッド トレーサー分析論による複雑な不均一コミュニティの微生物株の解析、その機能的関連性及び相互作用の決定、ならびに微生物アンサンブル(投与される微生物アンサンブル及び接種される微生物アンサンブルを含む)の合成、のための方法、装置、及びシステム
EP3562954A1 (en) 2016-12-28 2019-11-06 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
WO2018129249A1 (en) * 2017-01-05 2018-07-12 The University Of Chicago Inhibition of enteric infection through the modulation of microbiota
CN107058490B (zh) * 2017-01-12 2018-03-06 杨俊杰 肠道及口腔菌群多样性及差异性的分析方法
US10381105B1 (en) 2017-01-24 2019-08-13 Bao Personalized beauty system
BR112019015239A2 (pt) * 2017-02-28 2020-04-14 Kimberly Clark Co composição, e, método para manter um equilíbrio de microflora saudável na área urogenital de um paciente com necessidade do mesmo.
US10052026B1 (en) 2017-03-06 2018-08-21 Bao Tran Smart mirror
EP3606325B1 (en) 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
EP3606541A1 (en) 2017-04-05 2020-02-12 Crestovo Holdings LLC Compositions and methods for treating parkinson's disease (pd) and related disorders
US11040073B2 (en) 2017-04-05 2021-06-22 Finch Therapeutics Holdings Llc Compositions and methods for treating diverticulitis and related disorders
EP3388069B1 (en) 2017-04-12 2019-05-01 ETH Zurich Consortia of living bacteria useful for treatment of microbiome dysbiosis
US11044924B2 (en) 2017-04-28 2021-06-29 Native Microbials, Inc. Methods for supporting grain intensive and or energy intensive diets in ruminants by administration of a synthetic bioensemble of microbes or purified strains therefor
US11147792B2 (en) 2017-05-15 2021-10-19 Axial Therapeutics, Inc. Inhibitors of microbially induced amyloid
HUE054164T2 (hu) 2017-05-22 2021-08-30 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
CA3064773A1 (en) 2017-05-26 2018-11-29 Crestovo Holdings Llc Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same
LT3600363T (lt) 2017-06-14 2021-02-10 4D Pharma Research Limited Kompozicijos, apimančios bakterijų kamienus
MA49010B1 (fr) 2017-06-14 2020-11-30 4D Pharma Res Ltd Compositions comprenant une souche bactérienne du genre megasphaera et leurs utilisations
SMT202000695T1 (it) 2017-06-14 2021-01-05 4D Pharma Res Limited Composizioni comprendenti ceppi batterici
WO2018236979A1 (en) * 2017-06-20 2018-12-27 Cornell University Probiotic compositions and methods
CN111163785A (zh) * 2017-08-04 2020-05-15 第二基因组股份有限公司 作为生物疗法的人罗斯拜瑞氏菌、挑剔真杆菌及其组合
CN107854495B (zh) * 2017-08-04 2021-04-13 青岛东海药业有限公司 凝结芽孢杆菌在制备降低血尿酸制剂中的应用
SG11202001051SA (en) * 2017-08-06 2020-03-30 Second Genome Inc Streptococcus australis as a biotherapeutics
US20200360450A1 (en) * 2017-08-07 2020-11-19 Finch Therapeutics, Inc. Treatment of liver disease by modulation of the microbiome
CN111328284A (zh) 2017-08-07 2020-06-23 芬奇治疗公司 用于维持和恢复健康的肠道屏障的组合物和方法
US10682325B2 (en) 2017-08-14 2020-06-16 Axcella Health Inc. Compositions and methods for the treatment of liver diseases and disorders associated with one or both of hyperammonemia or muscle wasting
MX2020001774A (es) 2017-08-14 2020-09-09 Seres Therapeutics Inc Composiciones y métodos para tratar enfermedad colestásica.
TWI640314B (zh) * 2017-08-22 2018-11-11 長庚生物科技股份有限公司 戈氏副擬桿菌用於降低胰島素抗性及提升葡萄糖耐受性之用途
WO2019046401A1 (en) * 2017-08-29 2019-03-07 Evelo Biosciences, Inc. TREATMENT OF CANCER USING BLAUTIA STRAIN
US20200188310A1 (en) 2017-08-29 2020-06-18 Chr. Hansen A/S Stable capsules with fecal microbiota or a culture of microorganisms
WO2019046646A1 (en) 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
EP3453395B1 (en) 2017-09-08 2023-10-18 Deutsches Rheuma-Forschungszentrum Berlin Anaeroplasmatales for use in the treatment or prevention of an inflammatory disorder of the digestive system
MX2020002659A (es) 2017-09-08 2020-09-09 Evelo Biosciences Inc Vesiculas extracelulares bacterianas.
EP3688196A4 (en) * 2017-09-26 2021-07-14 Second Genome, Inc. GEMELLA SANGUINIS AS BIOTHERAPEUTICS
MX2020003992A (es) 2017-10-18 2020-08-13 Native Microbials Inc Aumento de la produccion de aves de corral mediante la administracion de un bioensamblaje sintetico de microbios o cepas purificadas de los mismos.
BR112020008552A2 (pt) * 2017-10-30 2020-12-29 Seres Therapeutics, Inc. métodos e composições para tratamento de resistência a antibiótico
FI128395B (en) * 2017-11-09 2020-04-30 Kemira Oyj Method for making a fibrous web
CN107653243B (zh) * 2017-11-15 2021-06-15 中国农业科学院农业基因组研究所 一种从肠道内容物中提取微生物宏基因组dna的方法
US12163135B2 (en) 2017-12-05 2024-12-10 BioPlx, Inc. Methods and compositions to prevent microbial infection
CN107828705A (zh) * 2017-12-31 2018-03-23 佛山市艳晖生物科技有限公司 一株解淀粉芽孢杆菌及其在防治孤独症上的应用
GB2585291B (en) 2018-02-02 2023-07-19 Univ Hong Kong Chinese Fecal fungome and therapeutic efficacy of fecal microbiota transplantation
WO2019156234A1 (en) * 2018-02-09 2019-08-15 Keio University Compositions and methods for the induction of cd8+ t-cells
CN112105371B (zh) * 2018-02-09 2024-12-17 内斯托尔株式会社 脂多糖控制性肠道细菌及其用途
CN110211629A (zh) * 2018-02-11 2019-09-06 中国科学院昆明动物研究所 一种评估微生物群落宏基因(或普通生物群落宏遗传)多样性和相似性的概念和方法
ES3032290T3 (en) 2018-03-20 2025-07-16 Theriva Biologics Inc Intestinal alkaline phosphatase formulations
US20210121505A1 (en) * 2018-03-29 2021-04-29 Seres Therapeutics, Inc. Compositions and methods for treating inflammatory bowel diseases
CN113038957A (zh) 2018-04-10 2021-06-25 谢尔塔治疗公司 微生物群
WO2019200271A1 (en) 2018-04-13 2019-10-17 White Dog Labs, Inc. An improved method for selecting probiotics
KR102225939B1 (ko) * 2018-04-19 2021-03-10 주식회사 고바이오랩 신규한 Bacteroides vulgatus 균주 및 이를 유효 성분으로 하는 면역 및 대사성 질환 예방 또는 치료용 조성물
EP3787401A4 (en) * 2018-04-30 2022-01-26 Suncor Energy Inc. MACROCYCLIC TETRAPYRROLE COMPOUNDS AND COMPOSITIONS AND METHODS FOR ENHANCING ABIOTIC STRESS RESISTANCE IN PLANTS
CN110468061B (zh) * 2018-05-11 2024-03-08 韩国亿诺生物有限公司 具有预防或治疗癌症的效果的新型菌株
WO2019226950A1 (en) 2018-05-23 2019-11-28 Brigham Young University Bacteriophage compositions and kits and related methods
US11986502B2 (en) 2018-05-23 2024-05-21 Optium, LLC Bacteriophage compositions and kits and related methods
MX2020012602A (es) * 2018-05-24 2021-03-31 Seres Therapeutics Inc Composiciones bacterianas dise?adas y usos de las mismas.
US20210121511A1 (en) * 2018-05-29 2021-04-29 Unm Rainforest Innovations Virus-like particle compositions and methods of using same
JP7397071B2 (ja) * 2018-06-07 2023-12-12 アルチュジェン セラピューティクス リミテッド C.ディフィシル治療方法及び組成物
CN112566649A (zh) * 2018-06-14 2021-03-26 雷柏奥提斯有限公司 微生物群恢复治疗(mrt)组合物和制造方法
JP2021527639A (ja) * 2018-06-19 2021-10-14 フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited 生物療法製品を含む剤形
JP2021527670A (ja) 2018-06-20 2021-10-14 アクセラ・ヘルス・インコーポレイテッドAxcella Health Inc. 筋肉中の脂肪浸潤の治療のための組成物及び方法
EP3594321A1 (en) * 2018-07-10 2020-01-15 Université catholique de Louvain Dusodibacter, a novel bacterial genus of the gastroinstestinal microbiota and uses thereof
US11166990B2 (en) 2018-07-13 2021-11-09 Finch Therapeutics Holdings Llc Methods and compositions for treating ulcerative colitis
CA3106315A1 (en) 2018-07-19 2020-01-23 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
WO2020033130A1 (en) 2018-08-06 2020-02-13 The Johns Hopkins University Treatment of irritable bowel syndrome with molybdenum
IL317775A (en) 2018-08-17 2025-02-01 Vedanta Biosciences Inc Methods for reducing imbalances in the bacterial population in the living body and restoring the microbiome
WO2020055547A2 (en) 2018-08-18 2020-03-19 Seed Health, Inc. Methods and compositions for honey bee health
WO2020041581A1 (en) * 2018-08-23 2020-02-27 Cornell University Methods and compositions for preventing and treating inflammatory bowel disease and nonalcoholic fatty liver disease
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications
CN113728088B (zh) 2018-09-13 2025-02-14 未知君有限责任公司 治疗胃肠障碍和炎性障碍的方法和组合物
US12509714B2 (en) 2018-09-21 2025-12-30 Emory University Multiple heteroresistance to guide combination antibiotic regimens
AU2019351017A1 (en) 2018-09-27 2021-04-29 Finch Therapeutics Holdings Llc. Compositions and methods for treating epilepsy and related disorders
CN109234195A (zh) * 2018-09-28 2019-01-18 邓州市汇海农业科技有限公司 一种稻田微生物复合菌剂
KR102135195B1 (ko) * 2018-10-08 2020-07-17 아주대학교산학협력단 테트라제노코커스 할로필러스를 포함하는 베체트병 또는 헤르페스 바이러스 감염증의 예방 또는 치료용 조성물
MA53860A (fr) * 2018-10-09 2021-09-15 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
WO2020079026A1 (en) * 2018-10-15 2020-04-23 Pharmabiome Ag A method of manufacturing a consortium of bacterial strains
EP3870154A4 (en) 2018-10-22 2022-07-27 Research Institute at Nationwide Children's Hospital COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF ANTIBIOTIC-INDUCED PATHOLOGIES USING PROBIOTICS IN BIOFILM STATE
AU2019376669A1 (en) * 2018-11-09 2021-06-10 The Brigham And Women's Hospital, Inc. Therapeutic microbiota for the treatment and/or prevention of dysbiosis
CN113454229A (zh) 2018-12-10 2021-09-28 诺沃梅生物技术股份有限公司 用于治疗高草酸尿症的方法和组合物
BR112021012767A2 (pt) * 2018-12-28 2021-09-21 General Probiotics, Inc. Composição farmaceuticamente aceitável para o tratamento de um animal e métodos
WO2020166708A1 (ja) * 2019-02-15 2020-08-20 コンビ株式会社 新規乳酸菌およびそれを含有する組成物
EP3923729B1 (en) 2019-02-15 2025-08-13 Nutrien Ag Solutions (Canada) Inc. The use of protoporphyrin ix derivatives to improve the health of plants
WO2020176564A1 (en) 2019-02-26 2020-09-03 The Regents Of The University Of Colorado, A Body Corporate Method and composition for treating gastrointestinal inflammatory disorders
CN110195027B (zh) * 2019-03-08 2022-03-01 大连理工大学 烟草节杆菌zl-1及其堆肥低温发酵菌剂的制备方法与应用
WO2020194298A1 (en) * 2019-03-25 2020-10-01 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of treating bovine mastitis
WO2020198503A1 (en) * 2019-03-26 2020-10-01 The Children's Medical Center Corporation Therapeutic microbiota for the treatment and/or prevention of dysbiosis
EA202193075A1 (ru) * 2019-05-10 2022-02-17 4Д Фарма Рисерч Лимитед Композиции, содержащие бактериальные штаммы
JP2022533456A (ja) * 2019-05-23 2022-07-22 アメリカン モレキュラー ラボラトリーズ インコーポレイテッド 糞便試料中のピロリ菌のレベルを検出するための方法
US20220233612A1 (en) * 2019-05-31 2022-07-28 South Dakota Board Of Regents Technology Transfer Office Probiotics to inhibit enteric pathogens
AU2020287084B2 (en) 2019-06-03 2025-12-18 Theriva Biologics, Inc. Alkaline phosphatase formulations and uses thereof
WO2020247536A1 (en) 2019-06-03 2020-12-10 Research Institute At Nationwide Children's Hospital Prebiotic formulations for prevention of sepsis and necroenterocolitis induced neurodevelopmental deficiencies
KR20220063153A (ko) * 2019-07-17 2022-05-17 유타대학연구재단 클로스트리디아 집합체 조성물 및 비만, 대사 증후군 및 과민성 대장 증후군을 치료하는 방법
AU2020316330A1 (en) 2019-07-19 2022-01-06 Finch Therapeutics Holdings Llc. Methods and products for treatment of gastrointestinal disorders
CN110358849A (zh) * 2019-07-30 2019-10-22 中国医学科学院北京协和医院 源于肠道的诊断胰腺炎的生物标志物、筛选方法及其用途
US20220287995A1 (en) * 2019-07-30 2022-09-15 The Regents Of The University Of California Compositions and methods for inhibiting bacterial virulence and flim-based device and method for antibiotic susceptibility testing
CN112438995A (zh) 2019-09-04 2021-03-05 台达电子工业股份有限公司 抑制具万古霉素抗药性肠球菌的益生菌及其组合与其用途
KR20220065793A (ko) * 2019-09-12 2022-05-20 마블바이옴 인코포레이티드 마이크로바이옴을 특성화하기 위한 조성물 및 방법
KR20220066904A (ko) 2019-09-24 2022-05-24 프롤랙타 바이오사이언스, 인코포레이티드 염증 및 면역 질환의 치료용 조성물 및 방법
JP7624449B2 (ja) 2019-10-07 2025-01-30 シオルタ・セラピューティクス,インコーポレイテッド 治療用医薬組成物
WO2021091981A1 (en) * 2019-11-04 2021-05-14 Vedanta Biosciences, Inc. Compositions and methods for enhancing immune checkpoint inhibitor therapy
WO2021108728A1 (en) * 2019-11-27 2021-06-03 Seres Therapeutics, Inc. Designed bacterial compositions and uses thereof
KR102215592B1 (ko) * 2019-12-11 2021-02-15 주식회사 에이치이엠 신규한 락토바실러스 퍼멘텀 hem 1036 균주, 및 상기 균주 또는 이의 배양물을 포함하는 장내 환경 개선용 조성물
CN114760976A (zh) 2019-12-16 2022-07-15 高露洁-棕榄公司 含有菊粉的口腔护理组合物
EP3838276A1 (en) * 2019-12-17 2021-06-23 Exeliom Biosciences Association of faecalibacterium prausnitzii strain cncm i-4573 with pentasa® for the treatment and prevention of gastrointestinal inflammation
TWI854077B (zh) * 2019-12-20 2024-09-01 瑞士商葛德瑪控股公司 生產肉毒桿菌毒素的方法
BR112022014917A2 (pt) 2020-01-27 2023-02-14 General Probiotics Inc Composições incluindo bactérias probióticas para a expressão e secreção de enterocinas para controlar a enterite necrótica induzida por clostridia perfringens em animais de pecuária e métodos relacionados
US11576937B2 (en) 2020-02-06 2023-02-14 Nch Corporation Method of reducing gut inflammation reduction in humans by consuming a heated probiotic composition
JP2023513702A (ja) * 2020-02-10 2023-04-03 ネイティブ マイクロビアルズ, インコーポレイテッド イヌの腸疾患およびディスバイオシスのための微生物組成物および使用方法
AU2021224185A1 (en) * 2020-02-18 2022-09-15 Memorial Sloan-Kettering Cancer Center Methods and compositions for identifying and treating subjects at risk of poor cancer survival
US20230172996A1 (en) * 2020-02-21 2023-06-08 Yoshikazu NAKAOKA Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension
WO2021173972A1 (en) * 2020-02-28 2021-09-02 Emory University Pentagalloyl glucose derived from schinus plants and methods of use
TW202146036A (zh) * 2020-04-28 2021-12-16 香港中文大學 針對covid-19的微生物的治療和診斷用途
WO2021221110A1 (ja) * 2020-04-29 2021-11-04 学校法人慶應義塾 Th1細胞及び/又はTh17細胞の増殖又は活性化を誘導する小腸内細菌
GB202007452D0 (en) * 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
EP4161541A4 (en) * 2020-06-09 2024-09-11 Flagship Pioneering Innovations VI, LLC PHYSIOLOGICALLY ACCEPTABLE COMPOSITIONS CONTAINING MICROORGANISMS OR MICROBIAL PRODUCTS
NL2025863B1 (en) 2020-06-19 2022-02-17 Acad Medisch Ct Fecal matter for treatment of cachexia
EP4189063A4 (en) * 2020-07-28 2024-08-07 Icahn School of Medicine at Mount Sinai COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL TRACT INFECTIONS
JP2023537608A (ja) 2020-08-14 2023-09-04 プロラクタ バイオサイエンス,インコーポレイテッド 細菌療法で使用するためのヒトミルクオリゴ糖組成物
CN112040091B (zh) 2020-09-01 2023-07-21 先临三维科技股份有限公司 相机增益的调整方法和装置、扫描系统
EP4210504A4 (en) * 2020-09-11 2024-12-18 MarvelBiome, Inc. METHODS AND USES OF MICROBIOME COMPOSITIONS
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof
KR102470808B1 (ko) * 2020-11-02 2022-11-28 주식회사 바이오미 염증성 장질환 예방 또는 치료용 조성물
US20240000859A1 (en) * 2020-11-25 2024-01-04 Seres Therapeutics, Inc. Designed bacterial compositions for treating graft-versus-host-disease
EP4288559B1 (en) * 2021-02-03 2025-11-26 Tata Consultancy Services Limited Method and system for designing personalized therapeutics and diet based on functions of microbiome
TWI807646B (zh) * 2021-02-19 2023-07-01 星聚樊生物科技有限公司 中草藥多醣及其細菌組成物改善疾病的用途
KR102373888B1 (ko) 2021-03-26 2022-03-15 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 변비 유무를 판별하는 방법 및 진단장치
KR102373886B1 (ko) 2021-03-26 2022-03-15 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 장염 유무를 판별하는 방법 및 진단 장치
CN113106042A (zh) * 2021-05-20 2021-07-13 广西壮族自治区兽医研究所 预防鸽形目念珠菌病的微生物菌剂、制剂及其制备方法和应用
NL2028324B1 (en) 2021-05-28 2022-12-12 Caelus Pharmaceuticals B V Insulin-sensitizing agent and butyrate-producing bacterium
WO2023006940A1 (en) * 2021-07-30 2023-02-02 Oncomedics Compositions and methods for decontaminating and culturing a gastrointestinal tract sample
KR102583365B1 (ko) * 2021-08-11 2023-09-27 코스맥스 주식회사 마이크로코커스 안타르크티쿠스 균주 및 그의 피부 상태 개선 용도
KR20240117164A (ko) * 2021-11-11 2024-07-31 콘체르토 바이오사이언시스, 아이엔씨. 피부 질환의 치료를 위한 미생물 조성물
CN116135205A (zh) * 2021-11-16 2023-05-19 葡萄王生技股份有限公司 戊醣片球菌gkp4用于制备改善肌少症之口服组成物的用途
EP4183403A1 (en) * 2021-11-19 2023-05-24 Lietuvos Sveikatos Mokslu Universitetas Modification of fecal microbiota with capsules containing gram-positive bacteria
JP2024542727A (ja) * 2021-12-02 2024-11-15 マーベルバイオーム・インコーポレイテッド 迷走神経関連疾患、障害、及び状態を治療するための方法、及び微生物叢組成物、成分、または代謝産物の使用
KR102438867B1 (ko) * 2022-03-11 2022-09-02 주식회사 바이오뱅크힐링 코프로코커스 캐터스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2023132628A1 (ko) * 2022-01-04 2023-07-13 주식회사 바이오뱅크힐링 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
CN114317368B (zh) * 2022-01-05 2022-09-09 中国水产科学研究院南海水产研究所 一种利用盐渍四生球菌改善快速发酵鱼露风味的方法
JP2025505760A (ja) * 2022-02-23 2025-02-28 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 腸内微生物叢におけるブラウチア・オベウムを増加/増強させることによって下痢の発生を低減するための組成物及び方法
WO2023212492A2 (en) * 2022-04-26 2023-11-02 Cedars-Sinai Medical Center Methanogens and prevotella as microbial convener for the treatment of diseases and diagnosis thereof
CN114965764B (zh) * 2022-05-18 2024-12-31 陕西安宁云生生物技术有限公司 便秘的诊断和治疗
CN115466690A (zh) * 2022-05-19 2022-12-13 同济大学 一种地芽孢杆菌新菌种及其培养方法和应用
AU2023319159A1 (en) * 2022-08-01 2025-02-06 Novel Biome Solutions Inc. Fecal microbiota transplant methods of manufacture
CN116790402B (zh) * 2023-01-14 2024-05-14 西北农林科技大学 一株具有抗炎特性的单形拟杆菌菌株、培养方法及应用
WO2025064408A1 (en) 2023-09-18 2025-03-27 The Broad Institute, Inc. Compositions and methods for treating cardiovascular disease
WO2025093777A1 (en) 2023-11-05 2025-05-08 Human Biome Institute S.A. Functional compositions and methods of use thereof in the treatment and recurrence prophylaxis of clostridioides difficile infection and restoration of healthy microbiota
WO2025147266A1 (en) * 2024-01-06 2025-07-10 Jose Vega Method of mitigation of death from epileptic seizures
WO2025189001A2 (en) * 2024-03-06 2025-09-12 University Of Florida Research Foundation, Incorporated Methods of reducing occurrence of neurodevelopmental disorders
CN118360215B (zh) * 2024-05-22 2025-03-07 吉林省农业科学院(中国农业科技东北创新中心) 一种用于降低反刍动物甲烷排放量的菌剂及其制备方法以及含有该菌剂的配合饲料

Family Cites Families (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3009864A (en) 1958-09-18 1961-11-21 Union Carbide Corp Process control
US3228838A (en) 1959-04-23 1966-01-11 Union Carbide Corp Preservation of biological substances
US3009861A (en) * 1961-01-13 1961-11-21 Alderton Gordon Isolation of bacterial spores
US3608030A (en) 1969-05-21 1971-09-21 Howard Tint Method of preparing a tablet dosage-form for the immunization of the intestinal tract with live virus preparations
US3892842A (en) * 1971-09-01 1975-07-01 Alza Corp Intrauterine contraceptive device for releasing steroid having double bond functionality
DE2414156A1 (de) * 1974-03-23 1975-09-25 Kleist Johann Georg Dr Arzneimittel zur beseitigung uraemischer symptome und verfahren zu seiner herstellung
US4077227A (en) 1976-11-12 1978-03-07 Regents Of The University Of Minnesota Method of freezing liquid material in which agglomeration is inhibited
US4205132A (en) 1978-07-17 1980-05-27 Microlife Technics, Inc. Lyophilization of bacteria
FI59925C (fi) 1980-01-11 1981-11-10 Esko Viljo Nurmi Foerfarande foer framstaellning av ett bakteriepreparat anvaendbart foer foerhindrande av salmonellainfektion hos fjaederfae
US4780987A (en) * 1983-10-25 1988-11-01 Plant Genetics, Inc. Method for the preparation of hydrated, pregerminated seeds in gel capsules
US4655047A (en) 1985-03-25 1987-04-07 I.Q.F. Inc. Process for freezing or chilling
JPS61252212A (ja) 1985-04-12 1986-11-10 Mitsubishi Petrochem Co Ltd 高吸水性ポリマ−の製造方法
US4839281A (en) 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
EP0439453B1 (en) 1987-10-12 1994-01-19 Exomed Australia Pty. Ltd. (ACN 051 976 446) Improved method for treatment of gastrointestinal disorders
US5045446A (en) 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
ATE165738T1 (de) 1988-08-02 1998-05-15 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
GB2233343B (en) 1989-06-30 1993-07-07 Farmos Oy A bacterial preparation for use in poultry
JP2961182B2 (ja) 1990-03-09 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
JP2961184B2 (ja) 1990-05-07 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
US5436002A (en) 1991-01-29 1995-07-25 Mycogen Corporation Bacillus thuringiensisisolate PS201T6 toxin
RU2035186C1 (ru) 1992-07-09 1995-05-20 Семен Рафаилович Резник Профилактический биопрепарат споролакт
WO1994008598A1 (en) 1992-10-09 1994-04-28 Advanced Tissue Sciences, Inc. Liver reserve cells
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US5851545A (en) * 1995-08-25 1998-12-22 Sandoz Ltd. Insecticidal matrix and process for preparation thereof
WO1997008598A1 (de) 1995-08-25 1997-03-06 Gff Technopark Verfahren zur simultanen, digitalen phasenempfindlichen detektion von zeitaufgelösten, quasi-gleichzeitig erfassten datenarrays eines periodisch stimulierten systems
DE69635496T2 (de) * 1995-09-15 2006-07-27 Gerding, Dale N., Chicago Verfahren und zusammensetzung zur vorbeugung und behandlung von mit clostridium difficile assoziierten erkrankungen
AUPO430496A0 (en) 1996-12-19 1997-01-23 Arnott's Biscuits Limited Prebiotics and probiotics
US6024370A (en) 1997-07-03 2000-02-15 Rockshox, Inc. Damping cartridge for high performance suspension systems
US5965128A (en) 1997-08-13 1999-10-12 University Of Georgia Research Foundation Inc. Control of enterohemorrhagic E. coli 0157:H7 in cattle by probiotic bacteria and specific strains of E. coli
US5951977A (en) 1997-10-14 1999-09-14 The United States Of America, As Represented By The Secretary Of Agriculture Competitive exclusion culture for swine
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
US6589771B1 (en) 1999-10-28 2003-07-08 Immunom Technologies, Inc. Methods for arousing dormant bacteria
US20030118547A1 (en) 2000-01-27 2003-06-26 Vandenberg Grant William Composition for intestinal delivery
AU2001233529A1 (en) 2000-02-10 2001-08-20 Andrew W. Bruce Probiotic therapy for newborns
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
AUPQ899700A0 (en) * 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
US7435427B2 (en) * 2000-09-22 2008-10-14 Galephar M/F Pharmaceutical semi-solid composition of isotretinoin
AU2100402A (en) 2000-11-30 2002-06-11 Bio Balance Corp Bacterial strain, processed plant extracts, compositions containing same, processes for their preparation and their therapeutic and industrial applications
KR100437497B1 (ko) * 2001-03-07 2004-06-25 주식회사 프로바이오닉 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제
AU2002353763B2 (en) 2001-05-04 2007-01-04 University Of Florida Research Foundation, Inc Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor
ITMI20011632A1 (it) 2001-07-27 2003-01-27 Sanofi Synthelabo Composizione solida contenente spore di batteri non patogeni del genere bacillus
GB0130789D0 (en) 2001-12-21 2002-02-06 King S College London Application of spores
US8383342B2 (en) 2002-04-24 2013-02-26 The University Of North Carolina At Greensboro Compositions, products, methods and systems to monitor water and other ecosystems
GB0212975D0 (en) 2002-06-06 2002-07-17 Mars Uk Ltd Mammalian animal composition
AU2002951692A0 (en) 2002-09-23 2002-10-17 Vital Biotech (Hong Kong) Limited Improvements in or relating to vaccines
WO2004069156A2 (en) 2003-01-30 2004-08-19 The Regents Of The University Of California Inactivated probiotic bacteria and methods of use thereof
US8617870B2 (en) 2003-03-13 2013-12-31 University Of Ottawa Antioxidant producing bacterium and uses thereof
CA2522957C (en) 2003-04-23 2013-10-22 Medarex, Inc. Compositions and methods for the therapy of inflammatory bowel disease
US7261861B2 (en) 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
EP1473370A3 (en) 2003-04-24 2005-03-09 BioMerieux, Inc. Genus, group, species and/or strain specific 16S rDNA Sequences
WO2004104175A2 (en) 2003-05-14 2004-12-02 University Of Georgia Research Foundation, Inc. Probiotic bacteria and methods
CA2535892A1 (en) 2003-08-18 2005-02-24 The Bio Balance Corporation A stable liquid probiotic composition, preparation and applications thereof
US7731976B2 (en) 2003-08-29 2010-06-08 Cobb And Company, Llp Treatment of irritable bowel syndrome using probiotic composition
US20050048515A1 (en) 2003-08-29 2005-03-03 Garner Bryan E. Methods for detecting and quantifying specific probiotic microorganisms in animal feed
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
ES2531971T3 (es) 2004-02-03 2015-03-23 Prevtec Microbia Inc. Uso de bacterias vivas para fomentar el crecimiento en animales
US7632520B2 (en) 2004-02-16 2009-12-15 Sanjeev Khandelwal Synergistic antibacterial formulation and to a method of making the same
US7854927B2 (en) 2004-05-11 2010-12-21 Ganeden Biotech, Inc. Methods and compositions for the dietary management of autoimmune disorders
US20090197249A1 (en) 2004-11-01 2009-08-06 George Mason University Compositions and methods for diagnosing colon disorders
ES2523316T3 (es) 2004-11-01 2014-11-24 Erber Aktiengesellschaft Bacteriófagos como agentes selectivos
US20060188523A1 (en) 2005-01-10 2006-08-24 Zhiheng Pei Methods for diagnosing and treating chronic tonsillitis
US7993667B2 (en) 2005-03-25 2011-08-09 Kimberly-Clark Worldwide, Inc. Methods of manufacturing a medicated tampon assembly
ES2607988T3 (es) 2005-05-31 2017-04-05 Iams Europe B.V. Bifidobacterias probióticas felinas
US7452872B2 (en) 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
EP1931363B1 (en) 2005-09-28 2015-11-18 Nordisk Rebalance A/S Treatment of ibd using both probiotic bacteria and fermented cereal as treatment effectors
US8968721B2 (en) * 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
WO2007136553A2 (en) 2006-05-18 2007-11-29 Biobalance Llc Bacterial strains, compositions including same and probiotic use thereof
US20090324638A1 (en) * 2006-06-12 2009-12-31 Biopeptides Corp. Live bacterial vaccine
JP5019563B2 (ja) 2006-06-16 2012-09-05 旭化成ケミカルズ株式会社 腸内細菌賦活剤
RU2009101475A (ru) 2006-06-20 2010-07-27 Конинклейке Филипс Электроникс, Н.В. (Nl) Электронная капсула и способ для лечения желудочно-кишечного заболевания
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EE05459B1 (et) 2006-12-08 2011-08-15 Tartu �likool Sporogeense Bacillus smithii tvi TBMI12 MSCL P737 ja selle endospooride kasutamine probiootikumina, toidulisandina ning probiootiline kompositsioon
WO2008076696A2 (en) 2006-12-18 2008-06-26 Washington University In St. Louis The gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
WO2008083157A2 (en) 2006-12-29 2008-07-10 Washington University In St. Louis Altering pgc-1alapha, ampk, fiaf, or the gastrointestinal microbiota as a means to modulate body fat and/or weight loss in a subject
EA017564B1 (ru) * 2007-09-12 2013-01-30 Тарганта Терапьютикс Корп. Способ ингибирования клостридиум диффициле введением оритаванцина
EP2207277A4 (en) 2007-10-16 2015-08-12 Fujitsu Ltd RELAY STATION DEVICE, DEVICE STATION DEVICE, WIRELESS COMMUNICATION SYSTEM AND LOAD DISTRIBUTION METHOD
US8236508B2 (en) 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
US8021654B2 (en) 2008-03-14 2011-09-20 Danisco A/S Methods of treating pigs with Bacillus strains
RU2010144789A (ru) 2008-04-01 2012-05-10 Метаметрикс Клиникал Лэборетери (Us) Процесс и способ мониторинга желудочно-кишечной микрофлоры
CN101264107A (zh) * 2008-05-09 2008-09-17 东北制药集团公司沈阳第一制药厂 地衣芽孢杆菌药物组合物及其制剂
CN102940652B (zh) 2008-05-28 2015-03-25 青岛东海药业有限公司 两形真杆菌制剂及其应用
JP2011528117A (ja) 2008-07-15 2011-11-10 メタノミクス ヘルス ゲーエムベーハー 胃バイパス及びそれに関連する状態を診断する手段及び方法
CN102131928A (zh) 2008-08-26 2011-07-20 奥林巴斯株式会社 粪便试样的调制方法、粪便试样调制用溶液、及粪便采集用试剂盒
WO2010030997A1 (en) 2008-09-12 2010-03-18 The Washington University Regulating intestinal microbiota dependent signaling as a means to modulate body fat and/or weight loss
EP2337569A4 (en) 2008-09-25 2013-04-03 Univ New York COMPOSITIONS AND METHODS FOR CHARACTERIZING AND RESTORING THE STOMACH DARM, SKIN AND NOSE MICROBIOTA
JP5620392B2 (ja) 2008-11-03 2014-11-05 タフツ ユニヴァーシティーTufts University クロストリジウム・ディフィシレ胞子の発芽および伸長を阻害するための方法および組成物
FR2938057B1 (fr) 2008-11-05 2013-05-17 Patrick Wozna Doseur a delta de pression
GB0821913D0 (en) * 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
IT1393931B1 (it) 2009-02-25 2012-05-17 Neuroscienze Pharmaness S C A R L Composizione di spore di batteri non patogeni
EP2432484A1 (en) 2009-04-30 2012-03-28 Compagnie Gervais Danone Use of collinsella aerofaciens for reducing bloating
CN102481322A (zh) 2009-05-01 2012-05-30 微制药有限公司 预防和治疗退化性疾病的细菌组合物
US9050276B2 (en) 2009-06-16 2015-06-09 The Trustees Of Columbia University In The City Of New York Autism-associated biomarkers and uses thereof
EP2446062B1 (en) 2009-06-26 2014-08-13 The Regents of the University of California Methods and systems for phylogenetic analysis
WO2011046614A2 (en) 2009-10-16 2011-04-21 The Regents Of The University Of California Methods and systems for phylogenetic analysis
WO2011005756A1 (en) 2009-07-06 2011-01-13 Puretech Ventures, Llc Delivery of agents targeted to microbiota niches
IN2012DN00878A (enExample) 2009-08-18 2015-05-22 Nestec Sa
WO2011022542A2 (en) 2009-08-19 2011-02-24 Puretech Ventures, Llc Administration of factors normally present in a microbial niche to improve health
US20120149584A1 (en) 2009-08-21 2012-06-14 Bernat Olle Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
ES2660008T3 (es) 2009-09-23 2018-03-20 Thomas Julius Borody Terapia para infecciones entéricas crónicas
US20120238468A1 (en) 2009-10-05 2012-09-20 Aak Patent B.V. Methods for diagnosing irritable bowel syndrome
US20110081320A1 (en) 2009-10-06 2011-04-07 Nubiome, Inc. Treatment/Cure of Autoimmune Disease
WO2011046616A2 (en) 2009-10-15 2011-04-21 New York University Methods for modulating bacterial infection
PH12012500687A1 (en) 2009-11-12 2012-10-29 Nestec Sa Nutritional composition for promoting gut microbiota balance and health
MX348611B (es) 2009-12-31 2017-06-21 Milton Trachtman Ira Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana.
US9492487B2 (en) 2010-02-01 2016-11-15 Matthew Ryan Garner Microbial product containing multiple microorganisms
RS63299B1 (sr) 2010-02-01 2022-07-29 Rebiotix Inc Bakterioterapija clostridium difficile kolitisa
WO2011103123A2 (en) 2010-02-16 2011-08-25 Arizona Technology Enterprises Reducing short-chain fatty acids and energy uptake in obese humans by managing their intestinal microbial communities
CA2791464A1 (en) 2010-03-01 2011-09-09 Institut National De La Recherche Agronomique Method of diagnosis of obesity
CN102939391A (zh) 2010-03-01 2013-02-20 国家农艺研究院 炎症性肠病的诊断方法
IT1398553B1 (it) 2010-03-08 2013-03-01 Probiotical Spa Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario.
WO2011113801A1 (en) 2010-03-16 2011-09-22 Universiteit Gent Use of clostridium perfringens strain 23 to protect against necrotic enteritis
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
JP5940064B2 (ja) 2010-07-06 2016-06-29 ノバルティス アーゲー 低用量のrnaを用いた大型哺乳動物の免疫化
WO2012009712A2 (en) 2010-07-16 2012-01-19 The Board Of Trustees Of The University Of Arkansas Methods and compositions including spore-forming bacteria for increasing the health of animals
FI20105825A7 (fi) 2010-07-26 2012-01-27 Suomen Punainen Risti Veripalvelu Veriryhmästatuksen käyttö III
NZ607043A (en) 2010-08-04 2015-05-29 Borody Thomas J Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
BR112013003895A2 (pt) 2010-08-19 2016-07-12 Merz Pharma Gmbh & Co Kgaa composição de enchimento e seu uso, processo para a preparação da composição de enchimento, kit e dispositivo de injeção
WO2012024638A2 (en) 2010-08-20 2012-02-23 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
WO2012033814A2 (en) 2010-09-10 2012-03-15 Viropharma Incorporated Environmental clostridial bacteriotherapy and related formulations and methods of manufacture and use
CA2813080A1 (en) 2010-10-04 2012-04-12 British Columbia Cancer Agency Branch Detection of fusobacterium in a gastrointestinal sample to diagnose gastrointestinal cancer
EP2637650A2 (en) 2010-11-10 2013-09-18 National Jewish Health Methods to test allergic conditions
US20120064592A1 (en) 2011-01-26 2012-03-15 Qteros, Inc. Biocatalysts synthesizing deregulated cellulases
JP5905032B2 (ja) 2011-02-09 2016-04-20 ラヴィヴォ・アーベー 腸管内微生物叢の回復および再構成のためのシンバイオティクス組成物
WO2012116289A2 (en) 2011-02-25 2012-08-30 Tricorder Diagnostics, Llc Microbial signatures as indicators of radiation exposure
CA2829385C (en) 2011-03-09 2021-07-13 Michael J. Sadowsky Compositions and methods for transplantation of colon microbiota
WO2012122522A2 (en) 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
WO2012142605A1 (en) * 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
US9411937B2 (en) 2011-04-15 2016-08-09 Verinata Health, Inc. Detecting and classifying copy number variation
US20120276056A1 (en) 2011-04-26 2012-11-01 Wieslaw Janusz Bochenek Method for Use of Biologic Agents Including Live or Dormant Forms of Bacteria and other organisms in Treating Infections, Inflammation and Other Diseases of Distal Small Intestine and Large Intestine
US20120278201A1 (en) 2011-04-26 2012-11-01 Dwolla Corp. Location transaction processing system
US20120284637A1 (en) 2011-05-02 2012-11-08 John Edward Boyer Unified Virtual Group Calendar System
WO2012159023A2 (en) 2011-05-19 2012-11-22 Virginia Commonwealth University Gut microflora as biomarkers for the prognosis of cirrhosis and brain dysfunction
US9579353B2 (en) 2011-06-10 2017-02-28 Prothera, Inc. Pharmaceutical compositions containing pediococcus and methods for reducing the symptoms of gastroenterological syndromes
WO2013008102A2 (en) 2011-07-14 2013-01-17 R.E.D. Laboratories N.V../ S.A. Methods and compositions for evaluating and/or treating chronic immune diseases
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
CA2843388A1 (en) 2011-07-27 2013-01-31 Max International, Llc Compositions comprising sugar-cysteine products
WO2013019896A1 (en) 2011-08-01 2013-02-07 Symbiotix Biotherapies, Inc. Platform for identifying and/or characterizing immunomodulatory agents
RU2613322C2 (ru) 2011-08-30 2017-03-15 Академис Медис Сентрум Способ профилактики и/или лечения инсулинорезистентности
WO2013037068A1 (en) 2011-09-14 2013-03-21 Queen's University At Kingston Method for treatment of disorders of the gastrointestinal system
WO2013066369A2 (en) 2011-10-03 2013-05-10 The Regents Of The University Of Michigan Methods for detecting graft-versus-host disease
US20130121968A1 (en) 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
EP2750682B1 (en) 2011-10-11 2016-05-18 Achim Biotherapeutics AB Composition comprising anaerobically cultivated human intestinal microbiota
EP3569690B1 (en) 2011-12-01 2024-08-28 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
GB201201766D0 (en) 2012-02-01 2012-03-14 Imp Innovations Ltd Method
US20150125883A1 (en) 2012-04-30 2015-05-07 Washington University Method of isolating and characterizing microorganisms that are targets of host immune responses
EP3686284A1 (en) 2012-05-18 2020-07-29 Genome Research Limited Methods and groups
WO2013176774A1 (en) 2012-05-25 2013-11-28 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
EP2854850B1 (en) 2012-05-25 2021-05-26 Sloan Kettering Institute For Cancer Research Compositions for treating or preventing radiation disease and gi syndrome
EP2684469A1 (en) 2012-07-13 2014-01-15 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Methods for strengthening and assessment of the natural defence of the colon against C. difficile overgrowth
US20140112985A1 (en) * 2012-10-22 2014-04-24 Polonez Therapeutics Llc Method of prevention and treatment of clostridium difficile infection
DK3628161T3 (da) * 2012-11-23 2023-05-30 Seres Therapeutics Inc Synergistiske bakterielle sammensætninger og fremgangsmåder til fremstilling og anvendelse deraf
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
WO2014121304A1 (en) 2013-02-04 2014-08-07 Seres Health, Inc. Compositions and methods
AU2014212004B2 (en) * 2013-02-04 2018-09-20 Société des Produits Nestlé S.A. Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases
WO2014153194A2 (en) 2013-03-14 2014-09-25 Seres Health, Inc. Methods for pathogen detection and enrichment from materials and compositions
EP2967077A4 (en) 2013-03-15 2016-09-14 Seres Therapeutics Inc NETWORK-BASED MICROBIAL COMPOSITIONS AND METHOD
CN105142654B (zh) 2013-05-03 2020-04-10 雀巢产品有限公司 肠小型生物群中的毛螺菌科和与体重的关联
KR102611070B1 (ko) 2013-11-25 2023-12-07 세레스 테라퓨틱스, 인코포레이티드 상승적 박테리아 조성물 및 그것의 생산 방법 및 용도
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
FI3146065T3 (fi) 2014-05-19 2025-02-12 Memorial Sloan Kettering Cancer Center Menetelmiä ja koostumuksia clostridium difficile -infektion vähentämiseksi
EP3223835B1 (en) 2014-11-25 2024-11-13 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
CN108348558A (zh) 2015-07-08 2018-07-31 赛里斯治疗公司 治疗结肠炎的方法
ES2938361T3 (es) 2015-11-24 2023-04-10 Seres Therapeutics Inc Composiciones de bacterias diseñadas
WO2017091753A1 (en) 2015-11-25 2017-06-01 Memorial Sloan-Kettering Cancer Center Methods and compositions for reducing vancomycin-resistant enterococci infection or colonization
CA3016911A1 (en) 2016-03-14 2017-09-21 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
BR112020008552A2 (pt) 2017-10-30 2020-12-29 Seres Therapeutics, Inc. métodos e composições para tratamento de resistência a antibiótico

Also Published As

Publication number Publication date
AU2020260564A1 (en) 2020-11-26
AU2014212003C1 (en) 2020-07-16
EP2953474A4 (en) 2016-12-28
EP2951285A4 (en) 2016-10-26
KR102222273B1 (ko) 2021-03-08
AU2018282348A1 (en) 2019-01-17
US20160243172A1 (en) 2016-08-25
US20190192581A1 (en) 2019-06-27
US11185562B2 (en) 2021-11-30
WO2014121302A2 (en) 2014-08-07
HK1219022A1 (zh) 2017-03-24
US9446080B2 (en) 2016-09-20
US20210244774A1 (en) 2021-08-12
US10064900B2 (en) 2018-09-04
RU2664479C2 (ru) 2018-08-17
JP2019116488A (ja) 2019-07-18
EP2951285A1 (en) 2015-12-09
JP2021181440A (ja) 2021-11-25
US10064901B2 (en) 2018-09-04
CN105451561A (zh) 2016-03-30
US9011834B1 (en) 2015-04-21
US10967011B2 (en) 2021-04-06
EP2953474A2 (en) 2015-12-16
US9180147B2 (en) 2015-11-10
US20250000915A1 (en) 2025-01-02
HK1218837A1 (zh) 2017-03-17
JP6942745B2 (ja) 2021-09-29
CN110917220A (zh) 2020-03-27
AU2014212004A1 (en) 2015-09-24
AU2014212003B2 (en) 2020-01-02
JP6908332B2 (ja) 2021-07-28
JP2016509002A (ja) 2016-03-24
EP3584308A2 (en) 2019-12-25
WO2014121298A3 (en) 2014-10-09
US9855303B2 (en) 2018-01-02
US20180200310A1 (en) 2018-07-19
WO2014121298A2 (en) 2014-08-07
AU2020202312B2 (en) 2022-11-24
NZ711771A (en) 2016-11-25
US20140328803A1 (en) 2014-11-06
EP2956006A2 (en) 2015-12-23
JP2019104742A (ja) 2019-06-27
US20170196914A1 (en) 2017-07-13
AU2023201132A1 (en) 2023-06-01
MX369877B (es) 2019-11-25
US20220249578A1 (en) 2022-08-11
US20160158294A1 (en) 2016-06-09
MX2019014045A (es) 2020-02-05
JP2024045100A (ja) 2024-04-02
BR112015018625A2 (pt) 2017-09-19
JP2016509003A (ja) 2016-03-24
AU2014212004B2 (en) 2018-09-20
HK1218559A1 (zh) 2017-02-24
AU2024202421A1 (en) 2024-06-27
KR102553134B1 (ko) 2023-07-07
JP7409743B2 (ja) 2024-01-09
US20160184370A1 (en) 2016-06-30
KR20230110367A (ko) 2023-07-21
AU2014212003A8 (en) 2015-10-22
AU2014212003A1 (en) 2015-09-24
US9585921B2 (en) 2017-03-07
AU2020202312A1 (en) 2020-04-23
EP2956006A4 (en) 2017-02-22
JP6479685B2 (ja) 2019-03-06
KR20210024683A (ko) 2021-03-05
EP3584308A3 (en) 2020-03-04
US20160199423A1 (en) 2016-07-14
EP3587558A3 (en) 2020-03-04
CA2899925A1 (en) 2014-08-07
MX2015009991A (es) 2016-02-05
US20190099455A1 (en) 2019-04-04
KR20150115888A (ko) 2015-10-14
US11730775B2 (en) 2023-08-22
WO2014121302A3 (en) 2014-10-09
WO2014121301A1 (en) 2014-08-07
EP3587558A2 (en) 2020-01-01
CA2899926A1 (en) 2014-08-07
US20150093360A1 (en) 2015-04-02
BR122021010444B1 (pt) 2022-07-12
RU2015137399A (ru) 2017-03-10
US20240050490A1 (en) 2024-02-15

Similar Documents

Publication Publication Date Title
US11730775B2 (en) Methods for treatment of Clostridium difficile infection or recurrence or symptoms thereof
US12409197B2 (en) Synergistic bacterial compositions and methods of production and use thereof
US20240408151A1 (en) Compositions and methods
AU2013347805B2 (en) Synergistic bacterial compositions and methods of production and use thereof

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

EEER Examination request

Effective date: 20190201

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241221

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20241221

D22 Grant of ip right intended

Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D22-D128 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: NOTICE OF ALLOWANCE IS ISSUED

Effective date: 20250314

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250317