BRPI0809842B8 - processo para a obtenção de linhagens de células aviárias diploides contínuas, processo de replicação de um vírus em uma linhagem de células aviárias diploides contínuas e processo de produção de peptídeos e proteínas recombinantes - Google Patents

processo para a obtenção de linhagens de células aviárias diploides contínuas, processo de replicação de um vírus em uma linhagem de células aviárias diploides contínuas e processo de produção de peptídeos e proteínas recombinantes

Info

Publication number
BRPI0809842B8
BRPI0809842B8 BRPI0809842A BRPI0809842A BRPI0809842B8 BR PI0809842 B8 BRPI0809842 B8 BR PI0809842B8 BR PI0809842 A BRPI0809842 A BR PI0809842A BR PI0809842 A BRPI0809842 A BR PI0809842A BR PI0809842 B8 BRPI0809842 B8 BR PI0809842B8
Authority
BR
Brazil
Prior art keywords
avian cell
continuous diploid
diploid avian
replicating
virus
Prior art date
Application number
BRPI0809842A
Other languages
English (en)
Inventor
Guehenneux Fabienne
Moreau Karine
Esnault Magali
Mehtali Majid
Original Assignee
Valneva
Vivalis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valneva, Vivalis filed Critical Valneva
Publication of BRPI0809842A2 publication Critical patent/BRPI0809842A2/pt
Publication of BRPI0809842A8 publication Critical patent/BRPI0809842A8/pt
Publication of BRPI0809842B1 publication Critical patent/BRPI0809842B1/pt
Publication of BRPI0809842B8 publication Critical patent/BRPI0809842B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17Newcastle disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/275Poxviridae, e.g. avipoxvirus
    • A61K39/285Vaccinia virus or variola virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/105Insulin-like growth factors [IGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/125Stem cell factor [SCF], c-kit ligand [KL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/13Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2306Interleukin-6 (IL-6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16051Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18451Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

processos para a obtenção de linhagens de células aviárias geneticamente estáveis contínuas, processo de replicação de um vírus em uma célula aviária 5 geneticamente estável contínua, vacinas e processo de produção de peptídeos e proteínas recombinantes. a presente invenção refere-se ao desenvolvimento e fabricação de vacinas virais. em particular, a invenção refere-se ao campo da produção industrial de vacinas e vetores virais, mais particular, ao uso de células-tronco embrionárias aviárias, de preferência, a linhagem de célula ebx® derivada de células-tronco embrionárias de pato, para a produção de vírus e vetores virais. a invenção é particularmente-útil para a produção industrial de vacinas virais para a prevenção de infecção viral de humanos e animais.
BRPI0809842A 2007-04-24 2008-04-23 processo para a obtenção de linhagens de células aviárias diploides contínuas, processo de replicação de um vírus em uma linhagem de células aviárias diploides contínuas e processo de produção de peptídeos e proteínas recombinantes BRPI0809842B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07300979A EP1985305A1 (en) 2007-04-24 2007-04-24 Duck embryonic derived stem cell lines for the production of viral vaccines
EP07300979.7 2007-04-24
PCT/EP2008/054912 WO2008129058A1 (en) 2007-04-24 2008-04-23 Duck embryonic derived stem cell lines for the production of viral vaccines

Publications (4)

Publication Number Publication Date
BRPI0809842A2 BRPI0809842A2 (pt) 2014-09-23
BRPI0809842A8 BRPI0809842A8 (pt) 2019-07-16
BRPI0809842B1 BRPI0809842B1 (pt) 2019-09-10
BRPI0809842B8 true BRPI0809842B8 (pt) 2021-05-25

Family

ID=38521810

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809842A BRPI0809842B8 (pt) 2007-04-24 2008-04-23 processo para a obtenção de linhagens de células aviárias diploides contínuas, processo de replicação de um vírus em uma linhagem de células aviárias diploides contínuas e processo de produção de peptídeos e proteínas recombinantes

Country Status (23)

Country Link
US (4) US20100062489A1 (pt)
EP (4) EP1985305A1 (pt)
JP (1) JP5539185B2 (pt)
KR (2) KR20150036788A (pt)
CN (1) CN101668539B (pt)
AU (1) AU2008240708B2 (pt)
BR (1) BRPI0809842B8 (pt)
CA (1) CA2684845C (pt)
CY (1) CY1114736T1 (pt)
DK (1) DK2150275T3 (pt)
EA (1) EA021064B1 (pt)
ES (2) ES2574827T3 (pt)
HK (1) HK1140964A1 (pt)
HR (1) HRP20131203T1 (pt)
IL (1) IL201679A (pt)
MX (1) MX343247B (pt)
MY (1) MY151119A (pt)
NZ (1) NZ581321A (pt)
PL (1) PL2150275T3 (pt)
PT (1) PT2150275E (pt)
SI (1) SI2150275T1 (pt)
WO (1) WO2008129058A1 (pt)
ZA (1) ZA200908152B (pt)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2836924B1 (fr) * 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
MX2009001477A (es) * 2006-08-09 2009-02-18 Vivalis Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas.
EP1985305A1 (en) 2007-04-24 2008-10-29 Vivalis Duck embryonic derived stem cell lines for the production of viral vaccines
KR101445433B1 (ko) * 2008-02-25 2014-09-26 백스터 인터내셔널 인코포레이티드 연속 세포주 제조 방법
JP2012507272A (ja) * 2008-11-05 2012-03-29 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 新規な方法
WO2010081890A1 (en) 2009-01-19 2010-07-22 Innate Pharma Anti-kir3d antibodies
US20110293660A1 (en) 2009-02-06 2011-12-01 Bruno Rene Andre Novel method
JP2012525830A (ja) * 2009-05-08 2012-10-25 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 均質化を含む細胞培養からのウイルスの製造方法
US8445270B2 (en) * 2009-05-12 2013-05-21 Transgene S.A. Immortalized avian cell lines and use thereof
GB0918830D0 (en) 2009-10-27 2009-12-09 Glaxosmithkline Biolog Niederl Process
GB0919117D0 (en) 2009-10-30 2009-12-16 Glaxosmithkline Biolog Sa Process
CA3177833A1 (en) 2009-12-15 2011-06-15 University Of Saskatchewan Vaccines for inclusion body hepatitis
CN102120983B (zh) * 2010-01-07 2013-04-03 中国农业科学院北京畜牧兽医研究所 北京鸭表皮干细胞的分离和培养方法
EP2531592A1 (en) 2010-02-04 2012-12-12 Vivalis Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
FR2956409A1 (fr) 2010-02-15 2011-08-19 Univ Claude Bernard Lyon Procedes pour optimiser la production virale par l'inactivation ou l'inhibition du gene hipk2 et cellules modifiees pour la production virale
EP2552490A4 (en) * 2010-03-26 2013-12-18 Emergent Product Dev Gaithersburg Inc INFLUENZA MATRIX 2 PROTEIN ECKTOMOMAS, EXPRESSION SYSTEM THEREFOR AND USES THEREOF
US20130039943A1 (en) 2010-05-03 2013-02-14 Bruno Rene Andre Novel method
GB201011502D0 (en) 2010-07-08 2010-08-25 Glaxosmithkline Biolog Sa Novel process
NZ604510A (en) 2010-08-17 2013-10-25 Csl Ltd Dilutable biocidal compositions and methods of use
CA2814643A1 (en) * 2010-10-15 2012-04-19 Tokyo Metropolitan Institute Of Medical Science Recombinant vaccinia virus having hemagglutinin protein genes derived from novel influenza viruses
FR2967072B1 (fr) 2010-11-05 2013-03-29 Univ Dundee Procede pour ameliorer la production de virus et semences vaccinales influenza
WO2012095514A1 (en) 2011-01-14 2012-07-19 Vivalis Recombinant protein production system
EP2724157B1 (en) 2011-06-27 2017-03-08 Valneva Method for screening cells
CA2850549C (en) 2011-09-30 2023-03-14 Teva Pharmaceuticals Australia Pty Ltd. Antibodies against tl1a and uses thereof
CA2852709A1 (en) 2011-10-28 2013-05-02 Patrys Limited Pat-lm1 epitopes and methods for using same
CN103157107A (zh) * 2011-12-14 2013-06-19 普莱柯生物工程股份有限公司 用连续传代细胞系生产鸡马立克氏病疫苗及方法
AR089231A1 (es) * 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
EP2660316A1 (en) 2012-05-02 2013-11-06 Helmholtz-Zentrum für Infektionsforschung GmbH Avian cell line and its use in production of protein
CN104812893B (zh) * 2012-11-22 2018-08-03 旭化成医疗株式会社 高感染滴度的细小病毒的生产方法
MX2015010023A (es) 2013-02-01 2017-11-17 Transbio Ltd Anticuerpos anti-cd83 y su uso.
CA2898618A1 (en) 2013-02-07 2014-08-14 Csl Limited Il-11r binding proteins and uses thereof
FR3008992A1 (fr) * 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
CA2920934C (en) * 2013-08-30 2022-12-06 Glaxosmithkline Biologicals S.A. Large scale production of viruses in cell culture
CN105177176A (zh) * 2014-06-13 2015-12-23 亚宝药业太原制药有限公司 一种腺病毒滴度的检测方法
WO2016008976A1 (en) 2014-07-16 2016-01-21 Transgene Sa Oncolytic virus for expression of immune checkpoint modulators
FR3025107B1 (fr) 2014-08-29 2018-10-05 Calixar Procede de preparation d'un antigene vaccinal, antigene vaccinal obtenu et utilisations
NZ731491A (en) 2014-10-23 2021-12-24 Kira Biotech Pty Ltd Cd83 binding proteins and uses thereof
AU2015336946A1 (en) 2014-10-23 2017-04-13 La Trobe University Fn14-binding proteins and uses thereof
WO2016097218A1 (en) 2014-12-17 2016-06-23 Fundación Para La Investigación Mèdica Aplicada Nucleic acid constructs and gene therapy vectors for use in the treatment of wilson's disease and other conditions
KR102526616B1 (ko) 2014-12-17 2023-04-27 푼다시온 파라 라 인베스티가시온 메디카 아플리카다 윌슨병 및 기타 병태의 치료에 사용되기 위한 핵산 구조물 및 유전자 치료용 벡터
WO2016131945A1 (en) 2015-02-20 2016-08-25 Transgene Sa Combination product with autophagy modulator
SG11201805894YA (en) 2016-01-11 2018-08-30 Forty Seven Inc Humanized, mouse or chimeric anti-cd47 monoclonal antibodies
CA3023022A1 (en) 2016-05-04 2017-11-09 Transgene Sa Combination therapy with cpg tlr9 ligand
CN107137704B (zh) * 2016-08-20 2020-02-21 山东信得科技股份有限公司 一种鸭2型腺病毒灭活疫苗
CA3036799A1 (en) 2016-09-28 2018-04-05 Bavarian Nordic A/S Compositions and methods for enhancing the stability of transgenes in poxviruses
WO2018069316A2 (en) 2016-10-10 2018-04-19 Transgene Sa Immunotherapeutic product and mdsc modulator combination therapy
WO2018091680A1 (en) 2016-11-18 2018-05-24 Transgene Sa Cowpox-based oncolytic vectors
CN106692964A (zh) * 2016-12-05 2017-05-24 扬州大学 一种血清4型禽腺病毒灭活苗及其制备方法
JP7110203B2 (ja) 2016-12-28 2022-08-01 トランジェーヌ 腫瘍溶解性ウイルスおよび治療用分子
CN107058243A (zh) * 2017-03-23 2017-08-18 华南农业大学 一种马立克氏病毒的悬浮培养方法
CA3062549A1 (en) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
JP2020519666A (ja) 2017-05-15 2020-07-02 ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. 安定性のウイルス含有組成物
US20200140821A1 (en) 2017-06-07 2020-05-07 Wild Type, Inc. Ex vivo meat production
SG11201912429RA (en) 2017-06-21 2020-01-30 Transgene Sa Personalized vaccine
WO2019020543A1 (en) 2017-07-28 2019-01-31 Transgene Sa ONCOLYTIC VIRUSES EXPRESSING AGENTS TARGETING METABOLIC IMMUNE MODULATORS
CN107794248A (zh) * 2017-10-24 2018-03-13 广州齐志生物工程设备有限公司 一种用微载体悬浮培养犬瘟热病毒的方法
MA50942A (fr) 2017-12-01 2020-10-07 Encoded Therapeutics Inc Protéines de liaison à l'adn modifiées
KR102121042B1 (ko) * 2017-12-06 2020-06-09 이정복 조류의 에그로부터 분리한 세포인 배반엽 전분화능세포, 신경줄기세포, 배아섬유아세포 컨디션드 배지를 유효성분으로 하는 세포 증식, 피부재생 및 주름 개선용 배지 조성물
CN108220227A (zh) * 2017-12-27 2018-06-29 华农(肇庆)生物产业技术研究院有限公司 一种通过全悬浮传代细胞系悬浮培养新城疫病毒的方法
CN108159412A (zh) * 2018-01-12 2018-06-15 华农(肇庆)生物产业技术研究院有限公司 一种生产细胞源鸡新城疫、禽流感二联灭活疫苗的方法及其产品
CN108261543B (zh) * 2018-02-08 2019-03-08 华农(肇庆)生物产业技术研究院有限公司 传代细胞源nd、ib、ai三联灭活疫苗的制备方法及其应用
CN108187039A (zh) * 2018-03-29 2018-06-22 山东信得动物疫苗有限公司 一种禽流感灭活疫苗生产工艺及产品
EP3794127A1 (en) 2018-05-14 2021-03-24 Vivet Therapeutics Gene therapy vectors comprising s/mar sequences
WO2020011754A1 (en) 2018-07-09 2020-01-16 Transgene Chimeric vaccinia viruses
CA3106286A1 (en) 2018-07-13 2020-01-16 Valneva Se Method for rescuing and producing a virus in avian cells
EP3617230A1 (en) 2018-09-03 2020-03-04 BioInvent International AB Novel antibodies and nucleotide sequences, and uses thereof
CN108977554B (zh) * 2018-09-05 2021-08-31 湖北省农业科学院畜牧兽医研究所 蛋鸭环状RNA circ_13034及其检测试剂、方法与应用
EP3847246A1 (en) 2018-09-06 2021-07-14 Bavarian Nordic A/S Storage improved poxvirus compositions
JP2022508724A (ja) 2018-10-12 2022-01-19 ヴィヴェ テラピューティクス 進行性家族性肝内胆汁鬱滞タイプ3(pfic3)の治療のためのコドン最適化導入遺伝子
SG11202104634UA (en) 2018-11-07 2021-06-29 Vivet Therapeutics Codon-optimized abcb11 transgene for the treatment of progressive familial intrahepatic cholestasis type 2 (pfic2)
TW202039854A (zh) 2018-11-16 2020-11-01 美商編碼製藥公司 治療威爾遜氏病的組合物和方法
US20220017859A1 (en) * 2018-11-23 2022-01-20 Valneva Se Food Products Comprising Avian Stem Cells
WO2020108735A1 (en) 2018-11-26 2020-06-04 Blink Biomedical Sas Antibodies to cytomegalovirus interleukin-10
WO2020117949A1 (en) * 2018-12-06 2020-06-11 Inventprise, Llc Bacterial growth on non-animal derived media
WO2020123876A1 (en) 2018-12-12 2020-06-18 Wild Type, Inc. Synthetic food compositions
US20220056481A1 (en) 2018-12-28 2022-02-24 Transgene M2-defective poxvirus
CN109593729A (zh) * 2018-12-29 2019-04-09 肇庆大华农生物药品有限公司 一种禽减蛋综合征病毒培养方法及其在疫苗中的应用
WO2020150411A1 (en) * 2019-01-17 2020-07-23 Boehringer Ingelheim Animal Health USA Inc. Serum-free medium for avian vaccine production and uses thereof
JP7212588B2 (ja) 2019-06-20 2023-01-25 オルガノ株式会社 水処理装置
CA3145446A1 (en) 2019-07-02 2021-01-07 Fundacion Para La Investigacion Medica Aplicada Cpla2e inducing agents and uses thereof
AU2021233167A1 (en) 2020-03-12 2022-09-22 Bavarian Nordic A/S Compositions improving poxvirus stability
CA3189238A1 (en) 2020-07-13 2022-01-20 Transgene Treatment of immune depression
TW202214864A (zh) 2020-08-06 2022-04-16 應用醫學研究基金會 用於藉基因療法治療諸如阿茲海默症之Tau蛋白病變的病毒顆粒
US20230265456A1 (en) 2020-08-10 2023-08-24 Fundacion Para La Investigacion Medica Aplicada Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis
CN112094819B (zh) * 2020-08-13 2022-10-14 浙江美保龙生物技术有限公司 一种鸡传染性法氏囊病毒的全悬浮培养方法
MX2023003994A (es) 2020-10-09 2023-04-24 UCB Biopharma SRL Construcciones de acido nucleico, vectores virales y particulas virales.
CN112442486B (zh) * 2020-11-05 2023-02-10 上海奥浦迈生物科技股份有限公司 一种维持体外培养cho dg44细胞后期活率的培养基及其应用
CN113699119A (zh) * 2020-12-10 2021-11-26 华农(肇庆)生物产业技术研究院有限公司 一种新城疫病毒及疫苗的无血清全悬浮培养制备方法
EP4267197A1 (en) 2020-12-23 2023-11-01 Vivet Therapeutics Minimal bile acid inducible promoters for gene therapy
WO2022148736A1 (en) 2021-01-05 2022-07-14 Transgene Vectorization of muc1 t cell engager
CN113278595B (zh) * 2021-04-28 2023-05-09 重庆永健生物技术有限责任公司 一种鸭腺病毒3型菌株、鸭腺病毒卵黄抗体及其制备方法和应用
WO2023025899A2 (en) 2021-08-26 2023-03-02 Transgene Delivery system for targeting genes of the interferon pathway
TW202321458A (zh) 2021-09-22 2023-06-01 瑞典商生物創新國際公司 新穎抗體組合及其用途
KR20240099360A (ko) 2021-10-28 2024-06-28 유씨비 바이오파마 에스알엘 핵산 구축물, 바이러스 벡터 및 바이러스 입자
WO2023213764A1 (en) 2022-05-02 2023-11-09 Transgene Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
WO2023213763A1 (en) 2022-05-02 2023-11-09 Transgene Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
WO2024003353A1 (en) 2022-07-01 2024-01-04 Transgene Fusion protein comprising a surfactant-protein-d and a member of the tnfsf
CN115449502B (zh) * 2022-08-15 2023-10-20 广东省华晟生物技术有限公司 无血清全悬浮培养型bhk-21-c细胞株及其构建方法与应用
TW202413636A (zh) 2022-08-18 2024-04-01 法商傳斯堅公司 嵌合痘病毒
WO2024188801A1 (en) * 2023-03-10 2024-09-19 Bavarian Nordic A/S Use of quail cell lines for poxvirus production

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US534740A (en) * 1895-02-26 Indicating door-bell
US5166065A (en) 1988-08-04 1992-11-24 Amrad Corporation Limited In vitro propagation of embryonic stem cells
US5162215A (en) 1988-09-22 1992-11-10 Amgen Inc. Method of gene transfer into chickens and other avian species
JPH05227947A (ja) 1992-01-14 1993-09-07 Rikagaku Kenkyusho 鳥類原始生殖細胞の分離方法
WO1993015185A1 (en) 1992-01-27 1993-08-05 North Carolina State University GENE TRANSFER IN POULTRY BY INTRODUCTION OF EMBRYO CELLS $i(IN OVO)
US5340740A (en) 1992-05-15 1994-08-23 North Carolina State University Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
WO1994003585A1 (en) 1992-08-04 1994-02-17 Commonwealth Scientific And Industrial Research Organisation A method for maintaining embryonic stem cells and avian factor useful for same
US5453357A (en) 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
US5589458A (en) 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
FR2726003B1 (fr) 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
JPH0924997A (ja) 1995-07-11 1997-01-28 Tokico Ltd 出荷装置
DE69738806D1 (de) 1996-10-10 2008-08-14 Invitrogen Corp Tierzellkulturmedium mit pflanzlichen nährstoffen
ATE271122T1 (de) 1996-11-12 2004-07-15 Pfizer Attenuierter lebender neospora impfstoff
JP2003517261A (ja) 1997-08-04 2003-05-27 ユニバシティ オブ マサチューセッツ、ア パブリック インスチチユーション オブ ハイアー エデュケイション オブ ザ コモンウエルス オブ マサチューセッツ、アズ リプリゼンテッド バイ イッツ アマースト キャンパス Pgcの長期間培養によるトリの胚生殖(eg)細胞系の産生、クローン形成およびキメラ形成へのその利用
CN1195844C (zh) 1997-08-04 2005-04-06 马萨诸塞州大学 鸟原始生殖细胞(pgc)细胞系及其长期培养的方法
US6406909B1 (en) 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
DE60037107T2 (de) 1999-02-11 2008-09-25 Hanmi Pharm. Co., Ltd. Pluripotente embryonale keimzellinie aus vögeln
DE19947407C2 (de) 1999-10-01 2002-08-01 Bayerische Motoren Werke Ag Datenbussystem für Kraftfahrzeuge
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
EP1520008B1 (en) 2002-07-09 2012-09-05 Baxter International Inc. Animal protein free media for cultivation of cells
AU2004257939B2 (en) * 2003-07-22 2008-06-05 Valneva Production of poxviruses with adherent or non adherent avian cell lines
EP1500699A1 (en) * 2003-07-22 2005-01-26 Vivalis Production of vaccinia virus with adherent or non adherent avian cell lines
EP1528101A1 (en) * 2003-11-03 2005-05-04 ProBioGen AG Immortalized avian cell lines for virus production
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
DK1979474T3 (da) * 2006-01-05 2010-09-20 Transgene Sa Aviær telomerase revers transkriptase
WO2007135133A1 (en) * 2006-05-19 2007-11-29 Vivalis Avian cell lines derived from primordial germ cells useful for the production of substances of interest
MX2009001477A (es) 2006-08-09 2009-02-18 Vivalis Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas.
EP1985305A1 (en) 2007-04-24 2008-10-29 Vivalis Duck embryonic derived stem cell lines for the production of viral vaccines

Also Published As

Publication number Publication date
US20140154741A1 (en) 2014-06-05
AU2008240708A1 (en) 2008-10-30
IL201679A (en) 2013-11-28
EP2150275A1 (en) 2010-02-10
EP2572728A1 (en) 2013-03-27
EP2150275B1 (en) 2013-11-13
EA200970996A1 (ru) 2010-04-30
MY151119A (en) 2014-04-15
JP2010524482A (ja) 2010-07-22
HRP20131203T1 (hr) 2014-02-14
SI2150275T1 (sl) 2014-04-30
EP2572727B1 (en) 2016-05-18
US9260694B2 (en) 2016-02-16
KR101624678B1 (ko) 2016-05-26
US20160257940A1 (en) 2016-09-08
ES2442009T3 (es) 2014-02-07
AU2008240708B2 (en) 2013-04-18
BRPI0809842A8 (pt) 2019-07-16
US9822345B2 (en) 2017-11-21
CA2684845C (en) 2017-12-05
CA2684845A1 (en) 2008-10-30
NZ581321A (en) 2012-05-25
WO2008129058A1 (en) 2008-10-30
ES2574827T3 (es) 2016-06-22
BRPI0809842A2 (pt) 2014-09-23
US20180135026A1 (en) 2018-05-17
MX2009011505A (es) 2009-11-09
EP1985305A1 (en) 2008-10-29
EA021064B1 (ru) 2015-03-31
US20100062489A1 (en) 2010-03-11
KR20150036788A (ko) 2015-04-07
PL2150275T3 (pl) 2014-03-31
IL201679A0 (en) 2010-05-31
JP5539185B2 (ja) 2014-07-02
KR20100017340A (ko) 2010-02-16
MX343247B (es) 2016-10-31
CN101668539A (zh) 2010-03-10
PT2150275E (pt) 2014-01-10
ZA200908152B (en) 2010-04-28
BRPI0809842B1 (pt) 2019-09-10
DK2150275T3 (da) 2014-01-13
EP2572727A1 (en) 2013-03-27
CN101668539B (zh) 2014-02-19
CY1114736T1 (el) 2016-12-14
HK1140964A1 (en) 2010-10-29

Similar Documents

Publication Publication Date Title
BRPI0809842B8 (pt) processo para a obtenção de linhagens de células aviárias diploides contínuas, processo de replicação de um vírus em uma linhagem de células aviárias diploides contínuas e processo de produção de peptídeos e proteínas recombinantes
WO2007048089A3 (en) Multi-plasmid system for the production of influenza virus
ATE398672T1 (de) Immortalisierte vogelzellinien zur virusproduktion
EP2465919A3 (en) Process of manufacturing viral vaccines in suspension avian embryonic derived stem cell lines
NZ596032A (en) Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
EA201892648A1 (ru) Вирусы пичинде с трехсегментным геномом в качестве векторных вакцин
BR112016007868A2 (pt) vacinas contra o vírus de epstein-barr
ATE469972T1 (de) Multiplasmid-system zur erzeugung des grippevirus
WO2005115448A3 (en) Multi plasmid system for the production of influenza virus
CL2008003794A1 (es) Virus de la estomatitis vesicular geneticamente modificado (vsv) que comprende por lo menos una mutacion de aminoacido en una region de alguna de las proteinas m, g y l del virus; metodo para producirlo; composicion inmunogenica que lo comprende; metodo para adaptar un virus en un cultivo celular.
WO2007095318A3 (en) Influenza antigens, vaccine compositions, and related methods
EA201390806A1 (ru) Конструкция пептидного каркаса
EA200801756A1 (ru) Противогриппозные вакцины, содержащие гемагглютинин и белки матрикса
FI3581650T3 (fi) IX-tekijän polypeptidimutantti, sen käyttöjä ja menetelmä sen valmistamiseksi
BR112014015390A8 (pt) vírus da estomatite vesicular para vacinas iniciais e de reforço
BR112014018884A2 (pt) antígenos amplamente reativos computacionalmente otimizados para viroses de influenza h3n2, h2n2, e b
WO2020109780A3 (en) Polypeptide and uses thereof
BR112020026620A8 (pt) Mutantes de hemaglutinina do vírus influenza
JP2017525766A5 (pt)
BR112014006654A2 (pt) processo para a preparação de uma dispersão e uso de hidrolisados de proteína como dispersantes
NO20085201L (no) Rekombinante novirhabdoviruser og deres anvendelse
UA60383U (ru) Способ получения фармацевтической композиции на основе модифицированных олигопептидов с антивирусными свойствами
NZ595176A (en) Influenza Viruses Able to Infect Canids, Uses Thereof
MX365437B (es) Metodo para seleccionar una linea celular permisiva para replicar virus aviares.
GB2475223A (en) A Paramyxoviridae family N protein-RNA complex in crystal form

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: VIVALIS (FR)

B25D Requested change of name of applicant approved

Owner name: VALNEVA (FR)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B25G Requested change of headquarter approved

Owner name: VALNEVA (FR)

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/09/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/09/2019, OBSERVADAS AS CONDICOES LEGAIS

B15G Petition not considered as such [chapter 15.7 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/04/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF