BR112014020156A8 - Derivado baseado em ácido hialurônico, método de preparação do derivado, hidrogel baseado no derivado de ligações cruzadas, método de produção do hidrogel e uso do hidrogel - Google Patents

Derivado baseado em ácido hialurônico, método de preparação do derivado, hidrogel baseado no derivado de ligações cruzadas, método de produção do hidrogel e uso do hidrogel

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Publication number
BR112014020156A8
BR112014020156A8 BR112014020156A BR112014020156A BR112014020156A8 BR 112014020156 A8 BR112014020156 A8 BR 112014020156A8 BR 112014020156 A BR112014020156 A BR 112014020156A BR 112014020156 A BR112014020156 A BR 112014020156A BR 112014020156 A8 BR112014020156 A8 BR 112014020156A8
Authority
BR
Brazil
Prior art keywords
hydrogel
derivative
preparation
cross
hyaluronic acid
Prior art date
Application number
BR112014020156A
Other languages
English (en)
Other versions
BR112014020156B1 (pt
BR112014020156A2 (pt
Inventor
Niedoba Krzystof
Wolfova Lucie
Foglarova Marcela
Pravda Martin
Nemcova Miroslava
Velebny Vladimir
Original Assignee
Contipro Biotech Sro
Contipro Pharma A S
Contipro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Contipro Biotech Sro, Contipro Pharma A S, Contipro As filed Critical Contipro Biotech Sro
Publication of BR112014020156A2 publication Critical patent/BR112014020156A2/pt
Publication of BR112014020156A8 publication Critical patent/BR112014020156A8/pt
Publication of BR112014020156B1 publication Critical patent/BR112014020156B1/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Birds (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)

Abstract

DERIVADO BASEADO EM ÁCIDO HIALURÔNICO, MÉTODO DE PREPARAÇÃO DO DERIVADO, HIDROGEL BASEADO NO DERIVADO DE LIGAÇÕES CRUZADAS, MÉTODO DE PRODUÇÃO DO HIDROGEL E USO DO HIDROGEL. A invenção refere-se a um novo derivado do hialuronano, de acordo com a fórmula geral (I), ao seu método de preparação, ao hidrogel baseado no novo derivado, ao método de preparação do hidrogel e ao uso do hidrogel na engenharia de tecidos, cosméticos, medicamentos ou medicamentos regenerativos, especialmente na forma de scaffolds para o tratamento da cartilagem articular ou defeitos no tecido ósseo.
BR112014020156-0A 2012-02-28 2013-02-26 Derivado baseado em ácido hialurônico, método de preparação do derivado, hidrogel baseado no derivado de ligações cruzadas, método de produção do hidrogel e uso do hidrogel BR112014020156B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZPV2012-136 2012-02-28
CZ20120136A CZ2012136A3 (cs) 2012-02-28 2012-02-28 Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
PCT/CZ2013/000023 WO2013127374A1 (en) 2012-02-28 2013-02-26 Derivates based on hyaluronic acid, capable of forming hydrogels, method of preparation thereof, hydrogels based on said derivatives, method of preparation thereof and use

Publications (3)

Publication Number Publication Date
BR112014020156A2 BR112014020156A2 (pt) 2017-06-20
BR112014020156A8 true BR112014020156A8 (pt) 2017-07-11
BR112014020156B1 BR112014020156B1 (pt) 2020-12-15

Family

ID=48047771

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014020156-0A BR112014020156B1 (pt) 2012-02-28 2013-02-26 Derivado baseado em ácido hialurônico, método de preparação do derivado, hidrogel baseado no derivado de ligações cruzadas, método de produção do hidrogel e uso do hidrogel

Country Status (12)

Country Link
US (1) US9492586B2 (pt)
EP (1) EP2820051B1 (pt)
JP (1) JP6247645B2 (pt)
KR (1) KR101953709B1 (pt)
BR (1) BR112014020156B1 (pt)
CZ (1) CZ2012136A3 (pt)
DK (1) DK2820051T3 (pt)
ES (1) ES2549668T3 (pt)
HU (1) HUE028115T2 (pt)
PL (1) PL2820051T3 (pt)
RU (1) RU2586931C2 (pt)
WO (1) WO2013127374A1 (pt)

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CZ305153B6 (cs) * 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
WO2016033337A1 (en) 2014-08-27 2016-03-03 The Cleveland Clinic Foundation Biocompatible tissue graft
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
KR101772642B1 (ko) * 2015-05-27 2017-08-29 광주과학기술원 하이브리드 중공 마이크로캡슐, 이를 포함하는 연조직용 스캐폴드, 및 이의 제조방법
CZ306479B6 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
US11530381B2 (en) * 2016-07-20 2022-12-20 The Johns Hopkins University Oxygen gradient hydrogel drug screening
CN118108677A (zh) 2017-01-27 2024-05-31 康奈尔大学 两性离子修饰的聚合物和水凝胶
IT201800007186A1 (it) * 2018-07-13 2020-01-13 Composizione per l’uso nel trattamento della parodontite e dei suoi effetti
JP7313370B2 (ja) * 2018-09-28 2023-07-24 Jsr株式会社 骨再生用組成物、骨再生用組成物キット、骨再生用部材および骨再生方法
KR102308721B1 (ko) * 2019-03-14 2021-10-06 주식회사 세라트젠 세로토닌 수식 히알루론산을 포함하는 하이드로젤 및 이의 용도
CZ2019360A3 (cs) * 2019-06-10 2020-12-23 Contipro A.S. Sada pro přípravu hydrogelu na bázi hydroxyfenylového derivátu hyaluronanu, způsob přípravy hydrogelu a jeho použití
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CN111135338A (zh) * 2019-12-31 2020-05-12 瑞希(重庆)生物科技有限公司 一种止血凝胶及其制备方法
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KR20220140440A (ko) 2021-04-09 2022-10-18 연세대학교 산학협력단 페놀 유도체로 수식된 셀룰로오스를 포함하는 하이드로젤 및 이의 용도
CN115212345A (zh) * 2022-06-07 2022-10-21 河南师范大学 一种多酚交联天然多糖基水凝胶敷料及其制备方法和应用

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BR112014020156B1 (pt) 2020-12-15
BR112014020156A2 (pt) 2017-06-20
US20150000561A1 (en) 2015-01-01
HUE028115T2 (en) 2016-11-28
ES2549668T3 (es) 2015-10-30
RU2586931C2 (ru) 2016-06-10
CZ303879B6 (cs) 2013-06-05
DK2820051T3 (en) 2015-10-19
US9492586B2 (en) 2016-11-15
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