AU2004274021B2 - 4'-thionucleosides and oligomeric compounds - Google Patents

4'-thionucleosides and oligomeric compounds Download PDF

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Publication number
AU2004274021B2
AU2004274021B2 AU2004274021A AU2004274021A AU2004274021B2 AU 2004274021 B2 AU2004274021 B2 AU 2004274021B2 AU 2004274021 A AU2004274021 A AU 2004274021A AU 2004274021 A AU2004274021 A AU 2004274021A AU 2004274021 B2 AU2004274021 B2 AU 2004274021B2
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Australia
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substituted
unsubstituted
alkyl
alkenyl
alkynyl
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AU2004274021A
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AU2004274021A1 (en
Inventor
Charles Allerson
Balkrishen Bhat
Prasad Dande
Richard H. Griffey
Thazha P. Prakash
Eric E. Swayze
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Ionis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc
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Priority to AU2009222605A priority Critical patent/AU2009222605B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AU2004274021A 2003-09-18 2004-09-20 4'-thionucleosides and oligomeric compounds Ceased AU2004274021B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2009222605A AU2009222605B2 (en) 2003-09-18 2009-10-07 4'-Thionucleosides and oligomeric compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50399703P 2003-09-18 2003-09-18
US60/503,997 2003-09-18
PCT/US2004/030874 WO2005027962A1 (en) 2003-09-18 2004-09-20 4’-thionucleosides and oligomeric compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2009222605A Division AU2009222605B2 (en) 2003-09-18 2009-10-07 4'-Thionucleosides and oligomeric compounds

Publications (2)

Publication Number Publication Date
AU2004274021A1 AU2004274021A1 (en) 2005-03-31
AU2004274021B2 true AU2004274021B2 (en) 2009-08-13

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AU2004274021A Ceased AU2004274021B2 (en) 2003-09-18 2004-09-20 4'-thionucleosides and oligomeric compounds
AU2009222605A Ceased AU2009222605B2 (en) 2003-09-18 2009-10-07 4'-Thionucleosides and oligomeric compounds

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AU2009222605A Ceased AU2009222605B2 (en) 2003-09-18 2009-10-07 4'-Thionucleosides and oligomeric compounds

Country Status (6)

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US (2) US7875733B2 (enExample)
EP (1) EP1677822B1 (enExample)
JP (1) JP5379347B2 (enExample)
AU (2) AU2004274021B2 (enExample)
CA (1) CA2538252C (enExample)
WO (1) WO2005027962A1 (enExample)

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