ATE264916T1 - Dns-konstrukten zur aktivierung und veränderung der expression von endogenen genen - Google Patents

Dns-konstrukten zur aktivierung und veränderung der expression von endogenen genen

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Publication number
ATE264916T1
ATE264916T1 AT96203412T AT96203412T ATE264916T1 AT E264916 T1 ATE264916 T1 AT E264916T1 AT 96203412 T AT96203412 T AT 96203412T AT 96203412 T AT96203412 T AT 96203412T AT E264916 T1 ATE264916 T1 AT E264916T1
Authority
AT
Austria
Prior art keywords
endogene
genes
alter
activate
expression
Prior art date
Application number
AT96203412T
Other languages
English (en)
Inventor
Scott C Chappel
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23806064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE264916(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE264916T1 publication Critical patent/ATE264916T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
AT96203412T 1989-12-22 1990-12-21 Dns-konstrukten zur aktivierung und veränderung der expression von endogenen genen ATE264916T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45478389A 1989-12-22 1989-12-22

Publications (1)

Publication Number Publication Date
ATE264916T1 true ATE264916T1 (de) 2004-05-15

Family

ID=23806064

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96203412T ATE264916T1 (de) 1989-12-22 1990-12-21 Dns-konstrukten zur aktivierung und veränderung der expression von endogenen genen
AT91903051T ATE156189T1 (de) 1989-12-22 1990-12-21 Modifikation der endogenen genexpression mit hilfe eines regulatorischen elements mittels homologe rekombination

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT91903051T ATE156189T1 (de) 1989-12-22 1990-12-21 Modifikation der endogenen genexpression mit hilfe eines regulatorischen elements mittels homologe rekombination

Country Status (26)

Country Link
EP (5) EP1484412A3 (de)
JP (3) JP3501286B2 (de)
KR (1) KR0176693B1 (de)
AR (1) AR245776A1 (de)
AT (2) ATE264916T1 (de)
AU (1) AU645294B2 (de)
BG (1) BG60624B1 (de)
BR (1) BR9007937A (de)
CA (1) CA2071989C (de)
DE (3) DE69034135T3 (de)
DK (2) DK0779362T4 (de)
ES (2) ES2151463T5 (de)
FI (1) FI107391B (de)
GR (1) GR3025057T3 (de)
HK (2) HK1000547A1 (de)
HU (1) HU217212B (de)
IL (4) IL96765A0 (de)
LT (1) LT3998B (de)
LV (1) LV10655B (de)
NO (1) NO311896B1 (de)
OA (1) OA09594A (de)
RO (1) RO109864B1 (de)
RU (1) RU2128227C1 (de)
UA (1) UA42675C2 (de)
WO (1) WO1991009955A1 (de)
ZA (1) ZA9010392B (de)

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LT3998B (en) 1996-06-25
IL96765A0 (en) 1991-09-16
UA42675C2 (uk) 2001-11-15
EP0505500A1 (de) 1992-09-30
EP1484412A3 (de) 2007-10-17
DE69031172D1 (de) 1997-09-04
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EP1375666A3 (de) 2007-09-26
AR245776A1 (es) 1994-02-28
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CA2071989C (en) 1999-07-27
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HU217212B (hu) 1999-12-28
AU7183691A (en) 1991-07-24
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DK0505500T3 (da) 1997-08-25
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DK0779362T3 (da) 2004-05-10
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EP0779362A1 (de) 1997-06-18
BR9007937A (pt) 1992-11-17
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