ATE331791T1 - Phosphodiesterase 10 - Google Patents

Phosphodiesterase 10

Info

Publication number
ATE331791T1
ATE331791T1 AT99934307T AT99934307T ATE331791T1 AT E331791 T1 ATE331791 T1 AT E331791T1 AT 99934307 T AT99934307 T AT 99934307T AT 99934307 T AT99934307 T AT 99934307T AT E331791 T1 ATE331791 T1 AT E331791T1
Authority
AT
Austria
Prior art keywords
polypeptides
pde10
polynucleotides
binding partners
expression constructs
Prior art date
Application number
AT99934307T
Other languages
English (en)
Inventor
Kate Loughney
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE331791T1 publication Critical patent/ATE331791T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT99934307T 1998-02-23 1999-02-23 Phosphodiesterase 10 ATE331791T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7550898P 1998-02-23 1998-02-23

Publications (1)

Publication Number Publication Date
ATE331791T1 true ATE331791T1 (de) 2006-07-15

Family

ID=22126229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934307T ATE331791T1 (de) 1998-02-23 1999-02-23 Phosphodiesterase 10

Country Status (8)

Country Link
US (4) US6350603B1 (de)
EP (1) EP1060251B1 (de)
JP (1) JP2002504341A (de)
AT (1) ATE331791T1 (de)
AU (1) AU3307999A (de)
CA (1) CA2321224A1 (de)
DE (1) DE69932153T2 (de)
WO (1) WO1999042596A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1223937A2 (de) * 1999-10-07 2002-07-24 Novaneuron Inc. Gen notwendung für striatale funktion, dessen verwendung, und verbindungen zur modulierung desselben
AU7999300A (en) * 1999-10-07 2001-05-10 Zymogenetics Inc. Novel human phosphodiesterase zcytor13
US20040152106A1 (en) * 1999-10-07 2004-08-05 Robertson Harold A. Gene necessary for striatal function, uses thereof, and compounds for modulating same
WO2002083883A2 (en) * 2001-04-11 2002-10-24 Altana Pharma Ag Human phosphodiesterase 9a isoform
IL149106A0 (en) * 2001-04-20 2002-11-10 Pfizer Prod Inc Therapeutic use of selective pde10 inhibitors
EP1666886A3 (de) * 2001-04-20 2006-06-21 Pfizer Products Inc. Verfahren zur Identifizierung eines selektiven PDE10 Hemmers
EP1321034A1 (de) * 2001-12-21 2003-06-25 Pfizer Products Inc. Unterbrechung des Phosphodiesterase 10 Gens
WO2004044235A1 (en) * 2002-11-13 2004-05-27 Bayer Healthcare Ag DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 7A1 (PDE7a1)
WO2004053494A1 (en) * 2002-12-09 2004-06-24 Bayer Healthcare Ag DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 9a2 (PDE9a2)
EP1573332A1 (de) * 2002-12-09 2005-09-14 Bayer HealthCare AG Diagnostik und therapie für krankheiten, die mit humane phosphodiesterase 9a3 (pde9a3) assoziiert sind
US20060166316A1 (en) * 2003-04-03 2006-07-27 Memory Pharmaceuticals Corporation Phosphodiesterase 10a7 isoforms and methods of use
CA2604349A1 (en) * 2005-02-28 2006-09-08 Nycomed Gmbh Method for identifying pde10 modulators
US7446345B2 (en) * 2005-04-29 2008-11-04 Cree, Inc. Light emitting devices with active layers that extend into opened pits
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
WO2007129183A2 (en) 2006-05-02 2007-11-15 Pfizer Products Inc. Bicyclic heteroaryl compounds as pde10 inhibitors
US7786139B2 (en) 2006-11-21 2010-08-31 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2008079111A1 (en) * 2006-12-20 2008-07-03 Carrier Corporation Method for determining refrigerant charge
US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
CN101917992A (zh) * 2007-03-27 2010-12-15 奥默罗斯公司 用于治疗运动障碍的pde7抑制剂的用途
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027279A1 (de) * 1980-07-18 1982-05-06 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Substituierte adenosin-3',5'-phosphorsaeurebenzyltriester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE69034135T3 (de) 1989-12-22 2012-08-23 Laboratoires Serono S.A. DNS-Konstrukten zur Aktivierung und Veränderung der Expression von endogenen Genen
JP3354149B2 (ja) * 1991-04-19 2002-12-09 ザ ボード オブ リージェンツ オブ ザ ユニヴァーシテイ オブ ワシントン 哺乳類ホスホジエステラーゼをコードするｄｎａ
EP0539573A4 (en) 1991-05-15 1993-12-29 Cell Genesys, Inc. Genomic modifications with homologous dna targeting
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
ATE438723T1 (de) * 1993-05-27 2009-08-15 Univ Washington Cyclisch gmp bindende cyclisch gmp spezifische phosphodiesterase materialien und verfahren
GB9518220D0 (en) 1995-09-06 1995-11-08 Medical Res Council Checkpoint gene
US5798246A (en) * 1996-03-25 1998-08-25 Incyte Pharmaceuticals, Inc. Cyclic nucleotide phosphodiesterase
US5922595A (en) 1997-12-09 1999-07-13 Incyte Pharmaceuticals, Inc. Cyclic GMP phosphodiesterase

Also Published As

Publication number Publication date
US20030044950A1 (en) 2003-03-06
EP1060251B1 (de) 2006-06-28
DE69932153D1 (en) 2006-08-10
CA2321224A1 (en) 1999-08-26
AU3307999A (en) 1999-09-06
US6864070B2 (en) 2005-03-08
JP2002504341A (ja) 2002-02-12
EP1060251A2 (de) 2000-12-20
US20050009062A1 (en) 2005-01-13
WO1999042596A2 (en) 1999-08-26
DE69932153T2 (de) 2007-05-31
US6350603B1 (en) 2002-02-26
US20030148378A1 (en) 2003-08-07
WO1999042596A3 (en) 2000-03-02
US6734003B2 (en) 2004-05-11

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Legal Events

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