ATE419351T1 - Thymus-stroma lymphopoietin rezeptor-moleküle und deren verwendung - Google Patents

Thymus-stroma lymphopoietin rezeptor-moleküle und deren verwendung

Info

Publication number
ATE419351T1
ATE419351T1 AT01948837T AT01948837T ATE419351T1 AT E419351 T1 ATE419351 T1 AT E419351T1 AT 01948837 T AT01948837 T AT 01948837T AT 01948837 T AT01948837 T AT 01948837T AT E419351 T1 ATE419351 T1 AT E419351T1
Authority
AT
Austria
Prior art keywords
thym
stroma
polypeptides
tslpr
receptor molecules
Prior art date
Application number
AT01948837T
Other languages
English (en)
Inventor
Christiaan Saris
Ming-Shi Chang
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22800712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE419351(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE419351T1 publication Critical patent/ATE419351T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01948837T 2000-06-28 2001-06-28 Thymus-stroma lymphopoietin rezeptor-moleküle und deren verwendung ATE419351T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21486600P 2000-06-28 2000-06-28

Publications (1)

Publication Number Publication Date
ATE419351T1 true ATE419351T1 (de) 2009-01-15

Family

ID=22800712

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01948837T ATE419351T1 (de) 2000-06-28 2001-06-28 Thymus-stroma lymphopoietin rezeptor-moleküle und deren verwendung

Country Status (13)

Country Link
US (3) US7964713B2 (de)
EP (2) EP1294879B1 (de)
JP (1) JP2004519205A (de)
AT (1) ATE419351T1 (de)
AU (2) AU7026601A (de)
CA (1) CA2413673C (de)
CY (1) CY1113145T1 (de)
DE (1) DE60137223D1 (de)
DK (1) DK2077279T3 (de)
ES (2) ES2391124T3 (de)
MX (1) MXPA02012747A (de)
PT (1) PT2077279E (de)
WO (1) WO2002000724A2 (de)

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US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
US20030099947A1 (en) 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
ATE362534T2 (de) 1998-11-13 2007-06-15 Immunex Corp Menschliche tslp nukleinsäuren und polypeptide
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
PT1417231E (pt) 2001-07-23 2013-07-29 Immunex Corp Linfopoietina estromal tímica humana modificada
AU2004257781B2 (en) * 2003-07-18 2009-07-16 Merck Sharp & Dohme Corp. Treatment and diagnosis of neoplasms using Thymic Stromal Lymphopoietin
US20060171943A1 (en) * 2005-02-01 2006-08-03 Amgen Inc. Compositions and methods of treating fibrotic disorders
EP2287196A3 (de) * 2006-01-13 2011-05-04 Irm Llc Antikörper gegen den Thymus-Stroma-Lymphopoietin-Rezeptor zur Behandlung von allergischen Krankheiten
UA108064C2 (uk) 2006-12-14 2015-03-25 Вектор експресії, що містить молекулу нуклеїнової кислоти, яка кодує ізольований тимусний стромальний лімфопоетичний білок (tslp) або його антигенний фрагмент
AR067045A1 (es) * 2007-06-20 2009-09-30 Irm Llc Metodos y composiciones para el tratamiento de enfermedades alergicas
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
MX2010008688A (es) * 2008-02-07 2010-08-30 Schering Corp Anticuerpos anti-receptor de linfopoyetina estromal timica procesados por ingenieria.
EP2213682A1 (de) 2009-01-30 2010-08-04 Institut Curie TSLP fördert Immunevasion und Persistenz von Viren
WO2012001889A1 (ja) * 2010-06-28 2012-01-05 国立大学法人東北大学 Tslpを恒常的に高発現する細胞、及び前記細胞を利用したtslp調節剤のスクリーニング方法
TW201201840A (en) 2010-07-15 2012-01-16 Hoffmann La Roche Antibodies specifically binding to human TSLPR and methods of use
ES2730978T3 (es) * 2013-08-09 2019-11-13 Astellas Pharma Inc Anticuerpo anti-receptor de TSLP humana nuevo
US9790506B2 (en) 2013-10-02 2017-10-17 The Regents Of The University Of California Diagnostic and screening methods for atopic dermatitis
SG11201604565WA (en) 2013-12-06 2016-07-28 Us Health Thymic stromal lymphopoietin receptor-specific chimeric antigen receptors and methods using same
CA2978026A1 (en) * 2015-03-11 2016-09-15 Glaxosmithkline Intellectual Property Development Limited Tslp binding proteins
EP3081227A1 (de) 2015-04-15 2016-10-19 Institut National De La Recherche Agronomique Tslp oder il-25 produzierende lactococcus lactis und deren verwendung als probiotika und therapeutika
MX2018007520A (es) 2015-12-18 2018-08-01 Astellas Pharma Inc Composicion farmaceutica que comprende un anticuerpo receptor de linfopoyetina estromal timica antihumano.
AU2017247966B2 (en) * 2016-04-05 2020-10-22 Universiteit Gent Novel TSLP inhibitors
CN115028722B (zh) * 2021-03-05 2024-09-03 拜西欧斯(北京)生物技术有限公司 抗tslp抗体及其制备方法和用途
WO2022255779A1 (ko) 2021-06-01 2022-12-08 주식회사 에즈큐리스 Jak 프로탁 키메라 분자 및 이를 포함하는 jak 관련 질환의 치료 또는 예방용 약학조성물
US12110324B2 (en) 2022-07-22 2024-10-08 Flagship Pioneering Innovations Vi, Llc Antigen binding molecules targeting thymic stromal lymphopoietin (TSLP)
CN120548195A (zh) 2022-11-07 2025-08-26 上游生物公司 包含抗人类tslp受体抗体的药物组合物和其使用方法
WO2025049345A1 (en) 2023-08-25 2025-03-06 Proteologix Us Inc. Anti-il-13 multispecific antibody constructs and uses thereof

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Also Published As

Publication number Publication date
US20110305705A1 (en) 2011-12-15
WO2002000724A2 (en) 2002-01-03
DK2077279T3 (da) 2012-12-03
US8911730B2 (en) 2014-12-16
CA2413673A1 (en) 2002-01-03
AU2001270266B2 (en) 2004-10-21
US20020068323A1 (en) 2002-06-06
EP1294879A2 (de) 2003-03-26
EP2077279B1 (de) 2012-09-05
EP1294879B1 (de) 2008-12-31
ES2317917T3 (es) 2009-05-01
US8344110B2 (en) 2013-01-01
DE60137223D1 (de) 2009-02-12
US20130084290A1 (en) 2013-04-04
ES2391124T3 (es) 2012-11-21
AU7026601A (en) 2002-01-08
CY1113145T1 (el) 2016-04-13
CA2413673C (en) 2018-01-09
JP2004519205A (ja) 2004-07-02
EP2077279A1 (de) 2009-07-08
PT2077279E (pt) 2012-09-14
US7964713B2 (en) 2011-06-21
MXPA02012747A (es) 2003-09-25
WO2002000724A3 (en) 2003-01-03

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