ATE362534T2 - Menschliche tslp nukleinsäuren und polypeptide - Google Patents

Menschliche tslp nukleinsäuren und polypeptide Download PDF

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Publication number
ATE362534T2
ATE362534T2 AT99960372T AT99960372T ATE362534T2 AT E362534 T2 ATE362534 T2 AT E362534T2 AT 99960372 T AT99960372 T AT 99960372T AT 99960372 T AT99960372 T AT 99960372T AT E362534 T2 ATE362534 T2 AT E362534T2
Authority
AT
Austria
Prior art keywords
polypeptides
nucleic acids
human tslp
tslp nucleic
purified
Prior art date
Application number
AT99960372T
Other languages
English (en)
Inventor
John Sims
Stewart Lyman
Hilary Mckenna
Allison Armstrong
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22322307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE362534(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE362534T2 publication Critical patent/ATE362534T2/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5418IL-7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99960372T 1998-11-13 1999-11-12 Menschliche tslp nukleinsäuren und polypeptide ATE362534T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10845298P 1998-11-13 1998-11-13

Publications (1)

Publication Number Publication Date
ATE362534T2 true ATE362534T2 (de) 2007-06-15

Family

ID=22322307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960372T ATE362534T2 (de) 1998-11-13 1999-11-12 Menschliche tslp nukleinsäuren und polypeptide

Country Status (14)

Country Link
US (8) US6555520B2 (de)
EP (1) EP1129190B2 (de)
JP (3) JP4454859B2 (de)
AT (1) ATE362534T2 (de)
AU (1) AU755562B2 (de)
CA (1) CA2349762C (de)
CY (1) CY1106806T1 (de)
DE (1) DE69936105T3 (de)
DK (1) DK1129190T4 (de)
ES (1) ES2288036T5 (de)
IL (3) IL143034A0 (de)
NZ (1) NZ512105A (de)
PT (1) PT1129190E (de)
WO (1) WO2000029581A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030099947A1 (en) * 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
WO2000017362A1 (en) * 1998-09-21 2000-03-30 Schering Corporation Human interleukin-b50, therapeutic uses
ATE362534T2 (de) * 1998-11-13 2007-06-15 Immunex Corp Menschliche tslp nukleinsäuren und polypeptide
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
PT1417231E (pt) * 2001-07-23 2013-07-29 Immunex Corp Linfopoietina estromal tímica humana modificada
AU2003208888B2 (en) * 2002-02-01 2006-10-19 Merck Sharp & Dohme Llc Uses of mammalian cytokine; related reagents
AU2004257781B2 (en) * 2003-07-18 2009-07-16 Merck Sharp & Dohme Corp. Treatment and diagnosis of neoplasms using Thymic Stromal Lymphopoietin
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
US20090156467A1 (en) * 2004-07-28 2009-06-18 Zhengbin Yao Thymic stromal lymphpoietin promoter and use therefor
US20060171943A1 (en) * 2005-02-01 2006-08-03 Amgen Inc. Compositions and methods of treating fibrotic disorders
CA2513350A1 (en) * 2005-03-02 2006-09-02 Sydney West Area Health Service Treatment for multiple sclerosis
EP2287196A3 (de) * 2006-01-13 2011-05-04 Irm Llc Antikörper gegen den Thymus-Stroma-Lymphopoietin-Rezeptor zur Behandlung von allergischen Krankheiten
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
SE532251C2 (sv) * 2006-11-28 2009-11-24 Theravac Pharmaceuticals Ab Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering
MX2009006471A (es) 2006-12-14 2009-06-26 Schering Corp Anticuerpo anti especifico de linfopoyetina estromal timica de diseño.
UA108064C2 (uk) 2006-12-14 2015-03-25 Вектор експресії, що містить молекулу нуклеїнової кислоти, яка кодує ізольований тимусний стромальний лімфопоетичний білок (tslp) або його антигенний фрагмент
TW201718635A (zh) 2007-03-06 2017-06-01 安美基公司 變異之活動素受體多肽及其用途
US8501678B2 (en) 2007-03-06 2013-08-06 Atara Biotherapeutics, Inc. Variant activin receptor polypeptides and uses thereof
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
KR20170105124A (ko) 2008-11-26 2017-09-18 암젠 인크 액티빈 iib 수용체 폴리펩타이드의 변이체 및 이의 용도
EP2213682A1 (de) 2009-01-30 2010-08-04 Institut Curie TSLP fördert Immunevasion und Persistenz von Viren
PE20121646A1 (es) 2009-11-04 2012-12-02 Merck Sharp & Dohme Anticuerpo anti-tslp modificado por tecnicas de ingeneria genetica
CN104379159A (zh) 2011-12-19 2015-02-25 安姆根公司 变体激活素受体多肽,单独或与化疗结合,及其用途
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
EP2916656B1 (de) 2012-11-09 2017-10-25 Cornell University Kleinmolekülige malt1-hemmer
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
AU2014212014A1 (en) 2013-02-01 2015-08-27 Amgen Inc. Administration of an anti-activin-A compound to a subject
US9708375B2 (en) 2013-03-15 2017-07-18 Amgen Inc. Inhibitory polypeptides specific to WNT inhibitors
EP2981280A2 (de) * 2013-04-04 2016-02-10 IEO - Istituto Europeo di Oncologia Srl Thymus-stroma-lymphopoetin fragmente und verwendungen davon
WO2015035215A1 (en) 2013-09-05 2015-03-12 Amgen Inc. Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
US10156562B2 (en) 2014-05-16 2018-12-18 Amgen Inc. Assay for detecting Th1 and Th2 cell populations
KR20170035891A (ko) 2014-06-13 2017-03-31 산타 마리아 바이오테라퓨틱스, 인코포레이티드 제형화된 수용체 폴리펩타이드 및 관련 방법
WO2016148437A1 (ko) * 2015-03-17 2016-09-22 고려대학교 산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
KR101843248B1 (ko) 2015-03-17 2018-03-29 고려대학교 세종산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
PT3347377T (pt) 2015-09-09 2021-04-30 Novartis Ag Anticorpos que se ligam à linfopoietina do estroma tímico (tslp) e métodos de utilização dos anticorpos
AU2016320748B2 (en) 2015-09-09 2019-05-02 Novartis Ag Thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of using the antibodies
JP7672196B2 (ja) 2017-03-14 2025-05-07 アムジエン・インコーポレーテツド 細胞培養において産生される抗体の総非フコシル化グリコフォームの調節
KR20200135781A (ko) 2018-03-26 2020-12-03 암젠 인크 세포 배양에서 생산된 항체의 총 비푸코실화 당형태
CN109678957B (zh) * 2018-12-06 2021-04-06 浙江工业大学 一种抗人tslp单克隆抗体及其制备与应用
KR102156335B1 (ko) * 2018-12-28 2020-09-16 (주)메디톡스 외래 단백질을 발현하는 미생물, 및 그의 용도
MX2022003461A (es) 2019-09-26 2022-04-19 Amgen Inc Metodos de produccion de composiciones de anticuerpos.
WO2021247892A1 (en) 2020-06-04 2021-12-09 Amgen Inc. Assessment of cleaning procedures of a biotherapeutic manufacturing process
MX2023004364A (es) 2020-10-15 2023-05-03 Amgen Inc Glucanos no emparejados relativos en metodos de produccion de anticuerpos.
AU2022289365A1 (en) 2021-06-07 2023-12-14 Amgen Inc. Using fucosidase to control afucosylation level of glycosylated proteins
AU2022361382A1 (en) 2021-10-05 2024-03-28 Amgen Inc. Fc-gamma receptor ii binding and glycan content
WO2023215725A1 (en) 2022-05-02 2023-11-09 Fred Hutchinson Cancer Center Compositions and methods for cellular immunotherapy
US12110324B2 (en) 2022-07-22 2024-10-08 Flagship Pioneering Innovations Vi, Llc Antigen binding molecules targeting thymic stromal lymphopoietin (TSLP)
AU2024256160A1 (en) 2023-04-20 2025-10-02 Amgen Inc. Methods of determining relative unpaired glycan content
WO2025038600A1 (en) 2023-08-14 2025-02-20 Amgen Inc. Methods for reducing yellow color
WO2025049345A1 (en) 2023-08-25 2025-03-06 Proteologix Us Inc. Anti-il-13 multispecific antibody constructs and uses thereof
WO2025101820A1 (en) 2023-11-08 2025-05-15 Fred Hutchinson Cancer Center Compositions and methods for cellular immunotherapy

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH07509223A (ja) 1992-04-30 1995-10-12 アムジェン インコーポレイテッド インターロイキン−1媒介疾患および腫瘍壊死因子媒介疾患の治療方法
EP0737071A1 (de) 1993-06-15 1996-10-16 Il- Yang Pharm. Co., Ltd. Anti-sense-oligodeoxynukleotide zu fibrogenen cytokinen und ihre verwendung
GB9702944D0 (en) 1997-02-13 1997-04-02 Univ Manchester Reducing fibrosis
US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
US6844170B1 (en) * 1998-03-19 2005-01-18 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
ATE490980T1 (de) 1998-03-19 2010-12-15 Human Genome Sciences Der gemeinsamen gamma-kette ähnlicher zytokinrezeptor
US20030099947A1 (en) * 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
WO2000017362A1 (en) * 1998-09-21 2000-03-30 Schering Corporation Human interleukin-b50, therapeutic uses
ATE362534T2 (de) 1998-11-13 2007-06-15 Immunex Corp Menschliche tslp nukleinsäuren und polypeptide
EP1140976A4 (de) 1998-12-30 2003-05-21 Millennium Pharm Inc Sekretierte proteine und ihre verwendungen.
US20010021380A1 (en) 1999-04-19 2001-09-13 Pluenneke John D. Soluble tumor necrosis factor receptor treatment of medical disorders
EP2241328A1 (de) 2000-05-12 2010-10-20 Immunex Corporation Interleukin-1 Inhibitoren zur Behandlung von Erkrankungen
MXPA02012747A (es) 2000-06-28 2003-09-25 Amgen Inc Moleculas del receptor de linfopoietina estromica timica y sus usos.
WO2002000723A2 (en) 2000-06-28 2002-01-03 Whitehead Institute For Biomedical Research Thymic stromal lymphopoietin receptor molecules and uses thereof
AU2003208888B2 (en) * 2002-02-01 2006-10-19 Merck Sharp & Dohme Llc Uses of mammalian cytokine; related reagents
HRP20020453A2 (en) 2002-05-23 2003-12-31 Pliva D D 1,3-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
ME00204B (me) 2002-09-06 2011-02-10 Medarex Llc Terapijsko, humano, monoklonsko anti-il-1r1antitijelo
AU2004257781B2 (en) 2003-07-18 2009-07-16 Merck Sharp & Dohme Corp. Treatment and diagnosis of neoplasms using Thymic Stromal Lymphopoietin
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
EP1793856A2 (de) 2004-08-20 2007-06-13 Amgen Inc. Verfahren und zusammensetzungen zur behandlung allergischer entzündungen
EP2287196A3 (de) 2006-01-13 2011-05-04 Irm Llc Antikörper gegen den Thymus-Stroma-Lymphopoietin-Rezeptor zur Behandlung von allergischen Krankheiten
GB0603683D0 (en) * 2006-02-23 2006-04-05 Novartis Ag Organic compounds
MX2009006471A (es) 2006-12-14 2009-06-26 Schering Corp Anticuerpo anti especifico de linfopoyetina estromal timica de diseño.
AR067045A1 (es) 2007-06-20 2009-09-30 Irm Llc Metodos y composiciones para el tratamiento de enfermedades alergicas
US9157749B2 (en) 2011-04-11 2015-10-13 Clarion Co., Ltd. Position calculation method and position calculation apparatus

Also Published As

Publication number Publication date
US20090017034A1 (en) 2009-01-15
IL195812A0 (en) 2011-08-01
IL143034A (en) 2009-07-20
DE69936105T3 (de) 2017-07-27
ES2288036T5 (es) 2017-07-06
US20030181360A1 (en) 2003-09-25
CY1106806T1 (el) 2012-05-23
JP2013078331A (ja) 2013-05-02
US20120014961A1 (en) 2012-01-19
EP1129190A1 (de) 2001-09-05
US20060223754A1 (en) 2006-10-05
JP2010088445A (ja) 2010-04-22
US9346870B2 (en) 2016-05-24
DE69936105D1 (de) 2007-06-28
US7786271B2 (en) 2010-08-31
EP1129190B2 (de) 2017-01-11
US6555520B2 (en) 2003-04-29
ES2288036T3 (es) 2007-12-16
IL143034A0 (en) 2002-04-21
US20100266601A1 (en) 2010-10-21
PT1129190E (pt) 2007-08-08
US20150005226A1 (en) 2015-01-01
US7405058B2 (en) 2008-07-29
US20020146819A1 (en) 2002-10-10
CA2349762C (en) 2013-12-24
EP1129190B1 (de) 2007-05-16
WO2000029581A1 (en) 2000-05-25
JP2002530079A (ja) 2002-09-17
US8444979B2 (en) 2013-05-21
AU1726600A (en) 2000-06-05
DK1129190T3 (da) 2007-09-24
JP4454859B2 (ja) 2010-04-21
IL195812A (en) 2012-04-30
NZ512105A (en) 2004-04-30
US7304144B2 (en) 2007-12-04
JP5632155B2 (ja) 2014-11-26
DK1129190T4 (en) 2017-04-03
AU755562B2 (en) 2002-12-12
DE69936105T2 (de) 2008-01-24
CA2349762A1 (en) 2000-05-25
US20130225490A1 (en) 2013-08-29

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