DE60031414D1 - Einkettige polypeptide enthaltend n-terminale troponin i fragmente und troponin c - Google Patents
Einkettige polypeptide enthaltend n-terminale troponin i fragmente und troponin cInfo
- Publication number
- DE60031414D1 DE60031414D1 DE60031414T DE60031414T DE60031414D1 DE 60031414 D1 DE60031414 D1 DE 60031414D1 DE 60031414 T DE60031414 T DE 60031414T DE 60031414 T DE60031414 T DE 60031414T DE 60031414 D1 DE60031414 D1 DE 60031414D1
- Authority
- DE
- Germany
- Prior art keywords
- troponin
- fragments
- terminal
- polypeptides containing
- unique polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 239000012634 fragment Substances 0.000 title 1
- 108090001027 Troponin Proteins 0.000 abstract 3
- 102000004903 Troponin Human genes 0.000 abstract 3
- 210000004898 n-terminal fragment Anatomy 0.000 abstract 2
- 101000851334 Homo sapiens Troponin I, cardiac muscle Proteins 0.000 abstract 1
- 108090000362 Lymphotoxin-beta Proteins 0.000 abstract 1
- 102000013534 Troponin C Human genes 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US368819 | 1995-01-05 | ||
US09/368,819 US6475785B1 (en) | 1997-12-18 | 1999-08-05 | Single-chain polypeptides comprising troponin I N-terminal fragments and troponin C |
PCT/IB2000/001105 WO2001011043A1 (en) | 1999-08-05 | 2000-08-07 | Single-chain polypeptides comprising troponin i n-terminal fragments and troponin c |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60031414D1 true DE60031414D1 (de) | 2006-11-30 |
DE60031414T2 DE60031414T2 (de) | 2008-04-10 |
Family
ID=23452875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60031414T Expired - Lifetime DE60031414T2 (de) | 1999-08-05 | 2000-08-07 | Einkettige polypeptide enthaltend n-terminale troponin i fragmente und troponin c |
Country Status (8)
Country | Link |
---|---|
US (1) | US6475785B1 (de) |
EP (1) | EP1200588B1 (de) |
AT (1) | ATE342978T1 (de) |
AU (1) | AU6310100A (de) |
CA (1) | CA2381439C (de) |
DE (1) | DE60031414T2 (de) |
ES (1) | ES2274799T3 (de) |
WO (1) | WO2001011043A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7078486B2 (en) * | 1999-12-10 | 2006-07-18 | Spectral Diagnostics, Inc. | Single-chain polypeptides comprising troponin I and troponin C |
US20030078614A1 (en) * | 2001-10-18 | 2003-04-24 | Amr Salahieh | Vascular embolic filter devices and methods of use therefor |
WO2004092214A2 (en) * | 2003-04-10 | 2004-10-28 | Aristex | Affinity purification system using troponin molecules as affinity ligands |
CN100334111C (zh) * | 2003-04-21 | 2007-08-29 | 刘凤鸣 | 抗肿瘤重组蛋白及其编码基因与应用 |
US7714100B2 (en) * | 2004-01-27 | 2010-05-11 | Compugen Ltd | Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease |
US11237163B2 (en) | 2016-03-07 | 2022-02-01 | Quidel Cardiovascular Inc. | Immunoassay controls and the use thereof |
CN105969880B (zh) * | 2016-06-21 | 2020-08-07 | 北京农学院 | 一种肉类成分四重pcr的检测方法及应用 |
CN110878116B (zh) * | 2018-09-05 | 2021-03-30 | 湖南永和阳光生物科技股份有限公司 | 一种稳定的重组心肌肌钙蛋白及其编码基因和应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
CA2027434C (en) | 1990-10-12 | 1999-01-05 | George Jackowski | Diagnostic kit for diagnosing and distinguishing chest pain in early onset thereof |
US5604105B1 (en) | 1990-10-12 | 1999-08-24 | Spectral Diagnostics Inc | Method and device for diagnosingand distinguishing chest pain in early onset thereof |
FR2701954B1 (fr) | 1993-02-23 | 1995-07-07 | Pasteur Sanofi Diagnostics | Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais. |
US5516637A (en) | 1994-06-10 | 1996-05-14 | Dade International Inc. | Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage |
US6248869B1 (en) | 1997-05-29 | 2001-06-19 | Medical Analysis Systems, Inc. | Troponin I forms and use of the same |
EP0983299A1 (de) | 1997-05-29 | 2000-03-08 | Medical Analysis Systems, Inc. | Kovalent-gekoppelte troponinkomplexen |
US6077676A (en) | 1997-12-18 | 2000-06-20 | Spectral Diagnostics, Inc. | Single-chain polypeptides comprising troponin I and troponin C |
-
1999
- 1999-08-05 US US09/368,819 patent/US6475785B1/en not_active Expired - Lifetime
-
2000
- 2000-08-07 AU AU63101/00A patent/AU6310100A/en not_active Abandoned
- 2000-08-07 CA CA2381439A patent/CA2381439C/en not_active Expired - Lifetime
- 2000-08-07 ES ES00949843T patent/ES2274799T3/es not_active Expired - Lifetime
- 2000-08-07 EP EP00949843A patent/EP1200588B1/de not_active Expired - Lifetime
- 2000-08-07 AT AT00949843T patent/ATE342978T1/de not_active IP Right Cessation
- 2000-08-07 DE DE60031414T patent/DE60031414T2/de not_active Expired - Lifetime
- 2000-08-07 WO PCT/IB2000/001105 patent/WO2001011043A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2381439C (en) | 2010-07-13 |
EP1200588A1 (de) | 2002-05-02 |
WO2001011043A1 (en) | 2001-02-15 |
US6475785B1 (en) | 2002-11-05 |
ES2274799T3 (es) | 2007-06-01 |
CA2381439A1 (en) | 2001-02-15 |
DE60031414T2 (de) | 2008-04-10 |
ATE342978T1 (de) | 2006-11-15 |
EP1200588B1 (de) | 2006-10-18 |
AU6310100A (en) | 2001-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |