DE69932247D1 - Menschlisches il-1 epsilon dna und polypeptide - Google Patents

Menschlisches il-1 epsilon dna und polypeptide

Info

Publication number
DE69932247D1
DE69932247D1 DE69932247T DE69932247T DE69932247D1 DE 69932247 D1 DE69932247 D1 DE 69932247D1 DE 69932247 T DE69932247 T DE 69932247T DE 69932247 T DE69932247 T DE 69932247T DE 69932247 D1 DE69932247 D1 DE 69932247D1
Authority
DE
Germany
Prior art keywords
polypeptides
human
fragmented peptides
polypeptide
epsilon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932247T
Other languages
English (en)
Other versions
DE69932247T2 (de
Inventor
E Sims
E Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of DE69932247D1 publication Critical patent/DE69932247D1/de
Publication of DE69932247T2 publication Critical patent/DE69932247T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
DE69932247T 1998-08-21 1999-08-20 Menschliches il-1 epsilon dna und polypeptide Expired - Lifetime DE69932247T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US9741398P 1998-08-21 1998-08-21
US97413P 1998-08-21
US9859598P 1998-08-31 1998-08-31
US98595P 1998-08-31
US9997498P 1998-09-11 1998-09-11
US99974P 1998-09-11
PCT/US1999/018771 WO2000011174A1 (en) 1998-08-21 1999-08-20 Human il-1 epsilon dna and polypeptides

Publications (2)

Publication Number Publication Date
DE69932247D1 true DE69932247D1 (de) 2006-08-17
DE69932247T2 DE69932247T2 (de) 2007-05-31

Family

ID=27378375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932247T Expired - Lifetime DE69932247T2 (de) 1998-08-21 1999-08-20 Menschliches il-1 epsilon dna und polypeptide

Country Status (13)

Country Link
US (1) US7659375B2 (de)
EP (1) EP1105485B1 (de)
JP (1) JP4444506B2 (de)
AT (1) ATE332373T1 (de)
AU (1) AU756913B2 (de)
CA (1) CA2340790C (de)
CY (1) CY1105226T1 (de)
DE (1) DE69932247T2 (de)
DK (1) DK1105485T3 (de)
ES (1) ES2263285T3 (de)
NZ (1) NZ510497A (de)
PT (1) PT1105485E (de)
WO (1) WO2000011174A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ510497A (en) 1998-08-21 2003-09-26 Immunex Corp Human IL-1 epsilon DNA and polypeptides
JP2003516132A (ja) * 1999-12-10 2003-05-13 アムジェン インコーポレイテッド インターロイキン−1レセプターアンタゴニスト様分子およびその使用
US8710014B2 (en) 2010-10-08 2014-04-29 Proteapex Therapeutics Llc Compositions and methods for inhibition of MMP13:MMP-substrate interactions
PE20211295A1 (es) 2018-12-21 2021-07-20 23Andme Inc Anticuerpos anti il-36 y procedimientos de uso de estos

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4411993A (en) * 1981-04-29 1983-10-25 Steven Gillis Hybridoma antibody which inhibits interleukin 2 activity
NZ201705A (en) 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4546082A (en) * 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4543439A (en) * 1982-12-13 1985-09-24 Massachusetts Institute Of Technology Production and use of monoclonal antibodies to phosphotyrosine-containing proteins
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4902614A (en) * 1984-12-03 1990-02-20 Teijin Limited Monoclonal antibody to human protein C
US5071972A (en) * 1986-01-31 1991-12-10 Genetics Institute, Inc. DNA sequences encoding novel thrombolytic proteins
GB8628398D0 (en) * 1986-11-27 1986-12-31 Central Blood Lab Authority Pharmaceutically-active conjugates
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
US4965195A (en) * 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4968607A (en) * 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
CA1340772C (en) 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
WO1990005183A1 (en) 1988-10-31 1990-05-17 Immunex Corporation Interleukin-4 receptors
DE69008521T2 (de) 1989-03-07 1994-10-20 Genentech Inc Kovalente konjugate von lipiden und oligonukleotiden.
JP3205331B2 (ja) * 1989-03-14 2001-09-04 和光純薬工業株式会社 アクロモバクタープロテアーゼi類遺伝子及びその遺伝子産物
CA2055435A1 (en) 1989-05-10 1990-11-11 Eli Gilboa Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter
WO1991004753A1 (en) 1989-10-02 1991-04-18 Cetus Corporation Conjugates of antisense oligonucleotides and therapeutic uses thereof
ATE139255T1 (de) 1989-10-24 1996-06-15 Gilead Sciences Inc Oligonukleotidanaloga mit neuartigen bindungen
US5350683A (en) * 1990-06-05 1994-09-27 Immunex Corporation DNA encoding type II interleukin-1 receptors
WO1991018982A1 (en) 1990-06-05 1991-12-12 Immunex Corporation Type ii interleukin-1 receptors
US5262522A (en) * 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
US5449758A (en) * 1993-12-02 1995-09-12 Life Technologies, Inc. Protein size marker ladder
US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
US5863769A (en) * 1997-01-28 1999-01-26 Smithkline Beecham Corporation DNA encoding interleukin-1 receptor antagonist (IL-1raβ)
US6197551B1 (en) * 1998-01-27 2001-03-06 Millennium Pharmaceuticals, Inc. Spoil-1 protein and nucleic acid molecules and uses therefor
AU7103198A (en) * 1997-04-21 1998-11-13 Schering Corporation Mammalian cytokines; related reagents and methods
WO1999035268A1 (en) 1998-01-09 1999-07-15 Immunex Corporation IL-1 delta DNA AND POLYPEPTIDES
NZ510497A (en) 1998-08-21 2003-09-26 Immunex Corp Human IL-1 epsilon DNA and polypeptides

Also Published As

Publication number Publication date
DE69932247T2 (de) 2007-05-31
AU756913B2 (en) 2003-01-23
AU5777799A (en) 2000-03-14
EP1105485B1 (de) 2006-07-05
WO2000011174A1 (en) 2000-03-02
DK1105485T3 (da) 2006-10-30
JP2002523046A (ja) 2002-07-30
PT1105485E (pt) 2006-11-30
US7659375B2 (en) 2010-02-09
NZ510497A (en) 2003-09-26
EP1105485A1 (de) 2001-06-13
CA2340790A1 (en) 2000-03-02
CA2340790C (en) 2012-07-10
US20080108796A1 (en) 2008-05-08
ATE332373T1 (de) 2006-07-15
JP4444506B2 (ja) 2010-03-31
ES2263285T3 (es) 2006-12-01
CY1105226T1 (el) 2010-03-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition