WO2000008180A3 - HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS - Google Patents

HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS Download PDF

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Publication number
WO2000008180A3
WO2000008180A3 PCT/US1999/017630 US9917630W WO0008180A3 WO 2000008180 A3 WO2000008180 A3 WO 2000008180A3 US 9917630 W US9917630 W US 9917630W WO 0008180 A3 WO0008180 A3 WO 0008180A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
encoding polypeptides
cdnas encoding
human cdnas
fragmented peptides
Prior art date
Application number
PCT/US1999/017630
Other languages
French (fr)
Other versions
WO2000008180A2 (en
Inventor
G Duke Virca
Timothy A Bird
Dirk M Anderson
John S Marken
Original Assignee
Immunex Corp
G Duke Virca
Timothy A Bird
Dirk M Anderson
John S Marken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp, G Duke Virca, Timothy A Bird, Dirk M Anderson, John S Marken filed Critical Immunex Corp
Priority to AU52543/99A priority Critical patent/AU5254399A/en
Priority to IL13543199A priority patent/IL135431A0/en
Priority to EP99937783A priority patent/EP1032687A2/en
Priority to JP2000563803A priority patent/JP2002524048A/en
Priority to CA002305308A priority patent/CA2305308A1/en
Priority to US09/509,902 priority patent/US6387676B1/en
Publication of WO2000008180A2 publication Critical patent/WO2000008180A2/en
Publication of WO2000008180A3 publication Critical patent/WO2000008180A3/en
Priority to US11/048,402 priority patent/US20050233355A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Abstract

The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in phosphorylation reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, the use of such polypeptides in screening assays, and kits comprising these reagents.
PCT/US1999/017630 1998-08-04 1999-08-03 HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS WO2000008180A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU52543/99A AU5254399A (en) 1998-08-04 1999-08-03 Human cdnas encoding polypeptides having kinase functions
IL13543199A IL135431A0 (en) 1998-08-04 1999-08-03 HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS
EP99937783A EP1032687A2 (en) 1998-08-04 1999-08-03 Human cdnas encoding polypeptides having kinase functions
JP2000563803A JP2002524048A (en) 1998-08-04 1999-08-03 Human cDNA encoding polypeptide having kinase function
CA002305308A CA2305308A1 (en) 1998-08-04 1999-08-03 Human cdnas encoding polypeptides having kinase functions
US09/509,902 US6387676B1 (en) 1998-08-04 1999-08-03 Human cDNAs encoding polypeptides having kinase functions
US11/048,402 US20050233355A1 (en) 1998-08-04 2005-01-31 Human cDNAs encoding polypeptides having kinase functions

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9527098P 1998-08-04 1998-08-04
US9997298P 1998-09-11 1998-09-11
US60/099,972 1998-09-11
US60/095,270 1998-09-11

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US09509902 A-371-Of-International 1999-08-03
US09/509,902 A-371-Of-International US6387676B1 (en) 1998-08-04 1999-08-03 Human cDNAs encoding polypeptides having kinase functions
US10/024,828 Division US6867013B2 (en) 1998-08-04 2001-12-18 Methods of screening for antagonists and agonists of polypeptides having kinase functions

Publications (2)

Publication Number Publication Date
WO2000008180A2 WO2000008180A2 (en) 2000-02-17
WO2000008180A3 true WO2000008180A3 (en) 2000-06-29

Family

ID=26790022

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017630 WO2000008180A2 (en) 1998-08-04 1999-08-03 HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS

Country Status (7)

Country Link
US (3) US6387676B1 (en)
EP (1) EP1032687A2 (en)
JP (1) JP2002524048A (en)
AU (1) AU5254399A (en)
CA (1) CA2305308A1 (en)
IL (1) IL135431A0 (en)
WO (1) WO2000008180A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000210086A (en) * 1999-01-25 2000-08-02 Jcr Pharmaceuticals Co Ltd Human tumor inhibitor gene
AU8010000A (en) * 1999-10-15 2001-04-30 Human Genome Sciences, Inc. Protein tyrosine kinase receptor polynucleotides, polypeptides, and antibodies
US6428980B1 (en) * 1999-11-16 2002-08-06 Rigel Pharmaceuticals, Inc. Nucleic acids encoding RIP3 associated cell cycle proteins
EP1297150A2 (en) * 2000-04-20 2003-04-02 Incyte Genomics, Inc. Human kinases
US6881542B1 (en) 2000-07-19 2005-04-19 Amgen Inc. Serine threonine kinase member, h2520-59
US7029892B1 (en) 2000-07-19 2006-04-18 Amgen, Inc. Serine threonine kinase member, h2520-59
CA2420105A1 (en) * 2000-08-31 2002-03-07 Incyte Genomics, Inc. Human kinases
AU2002311535A1 (en) * 2001-06-26 2003-01-08 Decode Genetics Ehf. Nucleic acids encoding protein kinases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495353B1 (en) 1998-01-21 2002-12-17 Sugen, Inc. Human orthologues of wart
US6084429A (en) 1998-04-24 2000-07-04 Xilinx, Inc. PLD having a window pane architecture with segmented and staggered interconnect wiring between logic block arrays
US6013455A (en) 1998-10-15 2000-01-11 Incyte Pharmaceuticals, Inc. Protein kinase homologs
US20100293669A2 (en) * 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
AU5173400A (en) 1999-05-28 2000-12-18 Sugen, Inc. Protein kinases
US6881542B1 (en) * 2000-07-19 2005-04-19 Amgen Inc. Serine threonine kinase member, h2520-59

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DEAK M. ET AL.: "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38 and may mediate activation of CREB.", EMBO JOURNAL, vol. 17, no. 15, 3 August 1998 (1998-08-03), pages 4426 - 4441, XP002126284 *
MARRA M. ET AL.: "The WashU-HHMI Mouse Project.", EMBL DATABASE ENTRY MM1263730; ACCESSION NUMBER AA472165, 21 June 1997 (1997-06-21), XP002126285 *
PIERRAT B. ET AL.: "RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38(alpha) mitogen-activated protein kinase (p38(alpha)MAPK).", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 45, 6 November 1998 (1998-11-06), pages 29661 - 29671, XP002126286 *

Also Published As

Publication number Publication date
IL135431A0 (en) 2001-05-20
US20030036051A1 (en) 2003-02-20
CA2305308A1 (en) 2000-02-17
WO2000008180A2 (en) 2000-02-17
US20050233355A1 (en) 2005-10-20
JP2002524048A (en) 2002-08-06
US6387676B1 (en) 2002-05-14
AU5254399A (en) 2000-02-28
EP1032687A2 (en) 2000-09-06
US6867013B2 (en) 2005-03-15

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