WO2001036635A3 - Neurite outgrowth-promoting factor homologue and nucleic acids encoding same - Google Patents

Neurite outgrowth-promoting factor homologue and nucleic acids encoding same Download PDF

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Publication number
WO2001036635A3
WO2001036635A3 PCT/US2000/031170 US0031170W WO0136635A3 WO 2001036635 A3 WO2001036635 A3 WO 2001036635A3 US 0031170 W US0031170 W US 0031170W WO 0136635 A3 WO0136635 A3 WO 0136635A3
Authority
WO
WIPO (PCT)
Prior art keywords
fctrx
nucleic acids
acids encoding
neurite outgrowth
encoding same
Prior art date
Application number
PCT/US2000/031170
Other languages
French (fr)
Other versions
WO2001036635A2 (en
Inventor
Kumud Majumder
Sudhirdas K Prayaga
Catherine Burgess
Original Assignee
Curagen Corp
Kumud Majumder
Sudhirdas K Prayaga
Catherine Burgess
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Kumud Majumder, Sudhirdas K Prayaga, Catherine Burgess filed Critical Curagen Corp
Priority to AU14868/01A priority Critical patent/AU1486801A/en
Publication of WO2001036635A2 publication Critical patent/WO2001036635A2/en
Publication of WO2001036635A3 publication Critical patent/WO2001036635A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides FCTRX, a novel isolated polypeptide, as well as a polynucleotide encoding FCTRX and antibodies that immunospecifically bind to FCTRX or any derivative, variant, mutant, or fragment of the FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
PCT/US2000/031170 1999-11-15 2000-11-15 Neurite outgrowth-promoting factor homologue and nucleic acids encoding same WO2001036635A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU14868/01A AU1486801A (en) 1999-11-15 2000-11-15 Novel growth factor polypeptides and nucleic acids encoding same

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US16573399P 1999-11-15 1999-11-15
US60/165,733 1999-11-15
US16614399P 1999-11-18 1999-11-18
US16617899P 1999-11-18 1999-11-18
US16628899P 1999-11-18 1999-11-18
US60/166,143 1999-11-18
US60/166,288 1999-11-18
US60/166,178 1999-11-18
US16747199P 1999-11-24 1999-11-24
US60/167,471 1999-11-24

Publications (2)

Publication Number Publication Date
WO2001036635A2 WO2001036635A2 (en) 2001-05-25
WO2001036635A3 true WO2001036635A3 (en) 2002-03-21

Family

ID=27538729

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031170 WO2001036635A2 (en) 1999-11-15 2000-11-15 Neurite outgrowth-promoting factor homologue and nucleic acids encoding same

Country Status (2)

Country Link
AU (1) AU1486801A (en)
WO (1) WO2001036635A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059618A2 (en) * 2000-11-16 2002-08-01 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
DE10211545A1 (en) * 2002-03-15 2003-10-02 Ihf Inst Fuer Hormon Und Fortp Use of polypeptides of human origin for the treatment of microbial infectious diseases
GB0228776D0 (en) * 2002-12-10 2003-01-15 Ares Trading Sa Splice variant
US8129139B2 (en) 2009-07-13 2012-03-06 Allergan, Inc. Process for obtaining botulinum neurotoxin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0476233A1 (en) * 1990-08-20 1992-03-25 American Cyanamid Company Human MK gene and protein sequence
EP0569703A2 (en) * 1992-04-24 1993-11-18 American Cyanamid Company Method of treating and preventing viral infections using HBNF and MK protein
WO1994013800A2 (en) * 1992-12-11 1994-06-23 Cancer Research Campaign Technology Limited Mk protein preparation and use in cell culture
WO1999054448A2 (en) * 1998-04-17 1999-10-28 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences, increased expression thereof in uterus myoma tissue

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0476233A1 (en) * 1990-08-20 1992-03-25 American Cyanamid Company Human MK gene and protein sequence
EP0569703A2 (en) * 1992-04-24 1993-11-18 American Cyanamid Company Method of treating and preventing viral infections using HBNF and MK protein
WO1994013800A2 (en) * 1992-12-11 1994-06-23 Cancer Research Campaign Technology Limited Mk protein preparation and use in cell culture
WO1999054448A2 (en) * 1998-04-17 1999-10-28 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences, increased expression thereof in uterus myoma tissue

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GEORGE D L ET AL: "THE GENES FOR GROWTH HORMONE AND CHORIONIC SOMATOMAMMOTROPIN ARE ON THE LONG ARM OF HUMAN CHROMOSOME 17 IN REGION Q21-QTER", HUMAN GENETICS, vol. 57, no. 2, 1981, pages 138 - 141, XP000993461, ISSN: 0340-6717 *
KRETSCHMER, P.J. ET AL.: "Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins.", GROWTH FACTORS, vol. 5, no. 2, 1991, pages 99 - 114, XP000993435 *

Also Published As

Publication number Publication date
AU1486801A (en) 2001-05-30
WO2001036635A2 (en) 2001-05-25

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