WO2001036644A3 - Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same - Google Patents

Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same Download PDF

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Publication number
WO2001036644A3
WO2001036644A3 PCT/US2000/031629 US0031629W WO0136644A3 WO 2001036644 A3 WO2001036644 A3 WO 2001036644A3 US 0031629 W US0031629 W US 0031629W WO 0136644 A3 WO0136644 A3 WO 0136644A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
fctrx
wnt
nucleic acids
acids encoding
Prior art date
Application number
PCT/US2000/031629
Other languages
French (fr)
Other versions
WO2001036644A2 (en
Inventor
Luca Rastelli
David Lewin
Bruce Taillon
David P Andrew
Original Assignee
Curagen Corp
Luca Rastelli
David Lewin
Bruce Taillon
David P Andrew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Luca Rastelli, David Lewin, Bruce Taillon, David P Andrew filed Critical Curagen Corp
Priority to EP00978769A priority Critical patent/EP1230370A2/en
Priority to AU16194/01A priority patent/AU784859B2/en
Priority to CA002391380A priority patent/CA2391380A1/en
Publication of WO2001036644A2 publication Critical patent/WO2001036644A2/en
Publication of WO2001036644A3 publication Critical patent/WO2001036644A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a derivative, variant, mutant, or fragment of an FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
PCT/US2000/031629 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same WO2001036644A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00978769A EP1230370A2 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same
AU16194/01A AU784859B2 (en) 1999-11-18 2000-11-17 WNT-regulated cytokine-like polypeptide and nucleic acids encoding same
CA002391380A CA2391380A1 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16617799P 1999-11-18 1999-11-18
US60/166,177 1999-11-18

Publications (2)

Publication Number Publication Date
WO2001036644A2 WO2001036644A2 (en) 2001-05-25
WO2001036644A3 true WO2001036644A3 (en) 2001-11-29

Family

ID=22602126

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031629 WO2001036644A2 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same

Country Status (2)

Country Link
EP (1) EP1230370A2 (en)
WO (1) WO2001036644A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059618A2 (en) * 2000-11-16 2002-08-01 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
AT412026B (en) * 2002-02-07 2004-08-26 Illmensee Karl Dr METHOD FOR DIAGNOSING A CYSTIC OVARIAL CARCINOMA
DE10361444A1 (en) * 2003-12-23 2005-07-21 Axaron Bioscience Ag Method for in vitro differentiation of neuronal stem cells or cells derived from neuronal stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034013A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. Chemotactic cytokine ii
WO1999047669A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences from tissue of breast tumors
WO2001000828A2 (en) * 1999-06-30 2001-01-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034013A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. Chemotactic cytokine ii
WO1999047669A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences from tissue of breast tumors
WO2001000828A2 (en) * 1999-06-30 2001-01-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 16 May 1997 (1997-05-16), M.M MARRA ET AL: "The WashU-HHMI Mouse EST project", XP002169411 *
DATABASE EMBL 19 April 1997 (1997-04-19), M.D. ADAMS ET AL: "EST186826 HCC cell line (metastasis to liver in mouse ) II Homo sapiens cDNA 5' end, mRNA sequence", XP002169413 *
DATABASE EMBL 30 August 2000 (2000-08-30), A. PIETAS ET AL: "Human cDNA of a new member of the S100 protein family which is down regulated in lung carcinoma cells", XP002169416 *
DATABASE EMBL 31 October 1997 (1997-10-31), M. MARRA ET AL: "The WashU-HHMI Mouse EST Project", XP002169412 *
DATABASE EMBL 8 January 1998 (1998-01-08), M. MARRA ET AL: "The WashU-HHMI Mouse EST project", XP002169414 *
DATABASE EMBL 8 May 1996 (1996-05-08), M. MARRA ET AL: "The WashU-HHMi Mouse EST Project", XP002169415 *
M.D. ADAMS ET AL: "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA", NATURE, vol. 377, no. 6547 suppl, 1995, pages 3 - 174 *
UNPUBLISHED *

Also Published As

Publication number Publication date
WO2001036644A2 (en) 2001-05-25
EP1230370A2 (en) 2002-08-14

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