DE69015566T2 - Umkehrbare Modifikation von biologischen Verbindungen zur Ermittlung, Trennung und Reinigung davon. - Google Patents

Umkehrbare Modifikation von biologischen Verbindungen zur Ermittlung, Trennung und Reinigung davon.

Info

Publication number
DE69015566T2
DE69015566T2 DE69015566T DE69015566T DE69015566T2 DE 69015566 T2 DE69015566 T2 DE 69015566T2 DE 69015566 T DE69015566 T DE 69015566T DE 69015566 T DE69015566 T DE 69015566T DE 69015566 T2 DE69015566 T2 DE 69015566T2
Authority
DE
Germany
Prior art keywords
purify
identify
separate
biological compounds
reversible modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69015566T
Other languages
English (en)
Other versions
DE69015566D1 (de
Inventor
James M Coull
Brian Gildea
Hubert Koester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Application granted granted Critical
Publication of DE69015566D1 publication Critical patent/DE69015566D1/de
Publication of DE69015566T2 publication Critical patent/DE69015566T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/12—Polycyclic non-condensed hydrocarbons
    • C07C15/16—Polycyclic non-condensed hydrocarbons containing at least two phenyl groups linked by one single acyclic carbon atom
DE69015566T 1989-10-23 1990-10-19 Umkehrbare Modifikation von biologischen Verbindungen zur Ermittlung, Trennung und Reinigung davon. Expired - Fee Related DE69015566T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,740 US5410068A (en) 1989-10-23 1989-10-23 Succinimidyl trityl compounds and a process for preparing same

Publications (2)

Publication Number Publication Date
DE69015566D1 DE69015566D1 (de) 1995-02-09
DE69015566T2 true DE69015566T2 (de) 1995-08-10

Family

ID=23687826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69015566T Expired - Fee Related DE69015566T2 (de) 1989-10-23 1990-10-19 Umkehrbare Modifikation von biologischen Verbindungen zur Ermittlung, Trennung und Reinigung davon.

Country Status (4)

Country Link
US (1) US5410068A (de)
EP (1) EP0424819B1 (de)
JP (1) JPH03279371A (de)
DE (1) DE69015566T2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7258977B1 (en) * 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US5612474A (en) * 1994-06-30 1997-03-18 Eli Lilly And Company Acid labile immunoconjugate intermediates
US5559000A (en) * 1995-01-18 1996-09-24 The Scripps Research Institute Encoded reaction cassette
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
AU2462497A (en) 1996-04-17 1997-11-19 Hubert Koster A combinatorial protecting group strategy for multifunctional molecules
ES2215241T3 (es) 1996-11-06 2004-10-01 Sequenom, Inc. Procedimiento de espectrometria de masa.
EP1164203B1 (de) * 1996-11-06 2007-10-10 Sequenom, Inc. DNA-Diagnostik mittels Massenspektrometrie
US6140053A (en) * 1996-11-06 2000-10-31 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
US6133436A (en) * 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
GB9625167D0 (en) * 1996-12-04 1997-01-22 Sandoz Ltd Organic compounds
US6110676A (en) * 1996-12-04 2000-08-29 Boston Probes, Inc. Methods for suppressing the binding of detectable probes to non-target sequences in hybridization assays
JP2001526776A (ja) * 1997-02-04 2001-12-18 シークエノム・インコーポレーテツド 生体分子を結合するための可逆性化学量論的工程
US6207370B1 (en) 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
US6962778B1 (en) 1997-09-25 2005-11-08 Boston Probes, Inc. Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
US6268131B1 (en) 1997-12-15 2001-07-31 Sequenom, Inc. Mass spectrometric methods for sequencing nucleic acids
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
EP1068216B1 (de) 1998-05-15 2003-12-10 Isis Innovation Limited Bibliotheken von unterschiedlich markierten oligomeren
CA2652991A1 (en) 2001-07-16 2003-11-13 Caprotec Bioanalytics Gmbh Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
DE60325847D1 (de) * 2002-03-11 2009-03-05 Caprotec Bioanalytics Gmbh Verbindungen und verfahren für die analyse des proteoms
DK2259068T3 (en) * 2003-01-16 2013-11-11 Caprotec Bioanalytics Gmbh Capture compounds and methods for analyzing the proteome
TW200533919A (en) * 2003-12-08 2005-10-16 Oxford Gene Tech Ip Ltd Derivatived molecules for mass spectrometry
EP1506959A3 (de) * 2004-09-22 2005-07-27 Oxford Gene Technology Ip Limited Derivatisierte Molekülen für Massenspektroskopie
CN101310183A (zh) 2005-11-16 2008-11-19 诺瓦提斯公司 用于脊髓损伤中抗Nogo-A抗体治疗的生物标记

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3440190A (en) * 1965-09-08 1969-04-22 Du Pont Oligonucleotide compositions and the process for the preparation thereof
IL74910A0 (en) * 1984-04-20 1985-07-31 Genentech Inc Rate enhancement for triester synthesis of oligonucleotides using a catalytic alcohol
US4968788A (en) * 1986-04-04 1990-11-06 Board Of Regents, The University Of Texas System Biologically reversible phosphate and phosphonate protective gruops
US4914210A (en) * 1987-10-02 1990-04-03 Cetus Corporation Oligonucleotide functionalizing reagents

Also Published As

Publication number Publication date
US5410068A (en) 1995-04-25
EP0424819B1 (de) 1994-12-28
EP0424819A1 (de) 1991-05-02
JPH03279371A (ja) 1991-12-10
DE69015566D1 (de) 1995-02-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PERSEPTIVE BIOSYSTEMS, INC., FRAMINGHAM, MASS., US

8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee