AU4401993A - Insertion of heterologous dna outside of known chromosomal genes - Google Patents

Insertion of heterologous dna outside of known chromosomal genes

Info

Publication number
AU4401993A
AU4401993A AU44019/93A AU4401993A AU4401993A AU 4401993 A AU4401993 A AU 4401993A AU 44019/93 A AU44019/93 A AU 44019/93A AU 4401993 A AU4401993 A AU 4401993A AU 4401993 A AU4401993 A AU 4401993A
Authority
AU
Australia
Prior art keywords
heterologous dna
chromosomal genes
known chromosomal
dna outside
outside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44019/93A
Inventor
Paul J Leibowitz
Patrice Milos
Samuel Wadsworth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exemplar Corp
Original Assignee
Exemplar Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exemplar Corp filed Critical Exemplar Corp
Publication of AU4401993A publication Critical patent/AU4401993A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests
AU44019/93A 1992-06-04 1993-06-04 Insertion of heterologous dna outside of known chromosomal genes Abandoned AU4401993A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89350692A 1992-06-04 1992-06-04
US893506 1992-06-04

Publications (1)

Publication Number Publication Date
AU4401993A true AU4401993A (en) 1993-12-30

Family

ID=25401689

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44019/93A Abandoned AU4401993A (en) 1992-06-04 1993-06-04 Insertion of heterologous dna outside of known chromosomal genes

Country Status (2)

Country Link
AU (1) AU4401993A (en)
WO (1) WO1993024642A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ289308B6 (en) 1993-12-23 2001-12-12 Merck & Co., Inc. Homologous recombinant expression vector for expression of recombinant genes and expression method recombinant genes
WO1996037626A1 (en) * 1995-05-22 1996-11-28 Chiron Corporation Position-specific integration of vector constructs into eukaryotic genomes mediated by a chimeric integrase protein
WO1998041645A1 (en) * 1997-03-14 1998-09-24 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
US5830698A (en) * 1997-03-14 1998-11-03 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1293460C (en) * 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
ES2090297T5 (en) * 1989-11-06 2005-03-01 Cell Genesys, Inc. PRODUCTION OF PROTEINS THAT USE HOMOLOGICAL RECOMBINATION.
EP0779362B2 (en) * 1989-12-22 2012-06-13 Laboratoires Serono SA DNA constructs for endogenous gene activation and expression modification
FR2670502B1 (en) * 1990-12-13 1994-09-16 Eurolysine "MULTISITE" INTEGRATION CASSETTE IN THE GENOME OF A YEAST, PROCESSED YEAST AND PROCESS FOR THE PREPARATION OF A PRODUCT OF INTEREST BY A YEAST THUS PROCESSED.
AU2305892A (en) * 1991-07-01 1993-02-11 Albert Einstein College Of Medicine Of Yeshiva University Interstitial deletion in chromosomal dna
SG49046A1 (en) * 1991-07-05 1998-05-18 American Cyanamid Co Method for identifying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegaloverirus

Also Published As

Publication number Publication date
WO1993024642A1 (en) 1993-12-09

Similar Documents

Publication Publication Date Title
AU3729393A (en) Boomerand DNA amplification
AU6042396A (en) Amplification of nucleic acid sequences
AP9300538A0 (en) New dna sequences
AU4068393A (en) Method of sequencing dna
NZ309645A (en) Chromosomal expression of heterologous genes in bacterial cells
AU2929495A (en) Nucleic acid sequence amplification method
AU3596593A (en) Oligonucleotide modulation of cell growth
AUPN741696A0 (en) Delivery of nucleic acids ii
EP0739411A4 (en) Chromosomal expression of heterologous genes in bacterial cells
AU5568694A (en) Stable oligonucleotides
AU6092394A (en) Amplification of nucleic acid sequences
AU4212897A (en) Method of preparing plasmid DNA
AU6950096A (en) Methods and compositions for nucleic acid targeting
AU4386393A (en) Process for gene targeting and genome manipulations
AU6714094A (en) Ocular delivery of nucleic acid
AU4401993A (en) Insertion of heterologous dna outside of known chromosomal genes
AU4800793A (en) Electrophoresis of nucleic acid fragments
AU3958895A (en) Membrane expression of heterologous genes
AU4045693A (en) Electrophoresis of nucleic acid fragments
AU3004695A (en) Nucleic acid filters
EP0830367A4 (en) High-affinity nucleic acid ligands of cytokines
GB9410170D0 (en) Nucleic acid
AU2750197A (en) Dna replication-regulating genes
AU5582194A (en) Virulence-specific bacterial dna sequence
AU5057093A (en) Simple nucleic acid amplification process