YU49221B - Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova - Google Patents

Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Info

Publication number
YU49221B
YU49221B YU21695A YU21695A YU49221B YU 49221 B YU49221 B YU 49221B YU 21695 A YU21695 A YU 21695A YU 21695 A YU21695 A YU 21695A YU 49221 B YU49221 B YU 49221B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
hydrogen atom
heteroatoms
medicines
procedure
Prior art date
Application number
YU21695A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU21695A (sh
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Francois Chantot
Alexis Denis
Odile Le Martret
Original Assignee
Roussel-Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel-Uclaf filed Critical Roussel-Uclaf
Publication of YU21695A publication Critical patent/YU21695A/sh
Publication of YU49221B publication Critical patent/YU49221B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
YU21695A 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova YU49221B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (2)

Publication Number Publication Date
YU21695A YU21695A (sh) 1997-12-05
YU49221B true YU49221B (sh) 2004-11-25

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
YU21695A YU49221B (sh) 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Country Status (49)

Country Link
US (2) US5656607A (cg-RX-API-DMAC10.html)
EP (1) EP0676409B1 (cg-RX-API-DMAC10.html)
JP (1) JP3000023B2 (cg-RX-API-DMAC10.html)
KR (1) KR100317148B1 (cg-RX-API-DMAC10.html)
CN (1) CN1059445C (cg-RX-API-DMAC10.html)
AP (1) AP587A (cg-RX-API-DMAC10.html)
AT (1) ATE234853T1 (cg-RX-API-DMAC10.html)
AU (1) AU684939B2 (cg-RX-API-DMAC10.html)
BG (1) BG61916B1 (cg-RX-API-DMAC10.html)
BR (1) BR9506147A (cg-RX-API-DMAC10.html)
CA (1) CA2164638C (cg-RX-API-DMAC10.html)
CO (1) CO4370097A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ296005B6 (cg-RX-API-DMAC10.html)
DE (1) DE69529934T2 (cg-RX-API-DMAC10.html)
DK (1) DK0676409T3 (cg-RX-API-DMAC10.html)
DZ (1) DZ1869A1 (cg-RX-API-DMAC10.html)
EE (1) EE04498B1 (cg-RX-API-DMAC10.html)
ES (1) ES2189820T3 (cg-RX-API-DMAC10.html)
FI (1) FI111264B (cg-RX-API-DMAC10.html)
FR (1) FR2718450B1 (cg-RX-API-DMAC10.html)
GB (1) GB2288174A (cg-RX-API-DMAC10.html)
GE (1) GEP19991836B (cg-RX-API-DMAC10.html)
HR (1) HRP950217B1 (cg-RX-API-DMAC10.html)
HU (1) HU215396B (cg-RX-API-DMAC10.html)
IL (1) IL112954A (cg-RX-API-DMAC10.html)
IS (1) IS1865B (cg-RX-API-DMAC10.html)
JO (1) JO1850B1 (cg-RX-API-DMAC10.html)
LV (1) LV11182B (cg-RX-API-DMAC10.html)
MA (1) MA23501A1 (cg-RX-API-DMAC10.html)
MD (1) MD663G2 (cg-RX-API-DMAC10.html)
MY (1) MY114672A (cg-RX-API-DMAC10.html)
NO (1) NO308361B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ284498A (cg-RX-API-DMAC10.html)
OA (1) OA10200A (cg-RX-API-DMAC10.html)
PE (1) PE2896A1 (cg-RX-API-DMAC10.html)
PL (1) PL180837B1 (cg-RX-API-DMAC10.html)
PT (1) PT676409E (cg-RX-API-DMAC10.html)
RO (1) RO115634B1 (cg-RX-API-DMAC10.html)
RU (1) RU2141965C1 (cg-RX-API-DMAC10.html)
SA (1) SA97170757A (cg-RX-API-DMAC10.html)
SI (1) SI0676409T1 (cg-RX-API-DMAC10.html)
SK (1) SK284079B6 (cg-RX-API-DMAC10.html)
SV (1) SV1995000018A (cg-RX-API-DMAC10.html)
TN (1) TNSN95026A1 (cg-RX-API-DMAC10.html)
TW (1) TW316908B (cg-RX-API-DMAC10.html)
UA (1) UA44705C2 (cg-RX-API-DMAC10.html)
WO (1) WO1995027720A1 (cg-RX-API-DMAC10.html)
YU (1) YU49221B (cg-RX-API-DMAC10.html)
ZA (1) ZA952059B (cg-RX-API-DMAC10.html)

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FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
KR20000011071A (ko) * 1996-05-07 2000-02-25 스티븐 에프. 웨인스톡 3-데스클라디노스-2,3-안하이드로에리트로마이신 유도체
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
WO1998009978A1 (en) * 1996-09-04 1998-03-12 Abbott Laboratories 6-o-substituted ketolides having antibacterial activity
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US6165986A (en) * 1997-03-10 2000-12-26 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
US6162794A (en) * 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
KR20010013660A (ko) * 1997-06-11 2001-02-26 실버스타인 아써 에이. 9-옥심 에리트로마이신 유도체
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
ATE298761T1 (de) 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
ATE344269T1 (de) 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
DE60030847T2 (de) * 1999-04-16 2007-04-19 Kosan Biosciences, Inc., Hayward Antiinfektiöse makrolidderivate
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
CN1351608A (zh) * 1999-05-24 2002-05-29 辉瑞产品公司 13－甲基红霉素衍生物
EP1404693A2 (en) 2001-07-03 2004-04-07 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
AU2003280305B2 (en) 2002-07-01 2008-05-01 Arkion Life Sciences Llc Process and materials for production of glucosamine and N-acetylglucosamine
WO2004080391A2 (en) * 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
JP2006524706A (ja) * 2003-04-25 2006-11-02 カイロン コーポレイション 新規なケトライド誘導体
CA2523134A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
US9453042B2 (en) * 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
CN102245195B (zh) 2008-10-24 2016-01-13 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
PL2550286T3 (pl) 2010-03-22 2016-07-29 Cempra Pharmaceuticals Inc Krystaliczne postaci makrolidu i ich zastosowanie
CA2799937A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
SG11201405895UA (en) 2012-03-27 2014-10-30 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
HK1218864A1 (zh) 2013-03-15 2017-03-17 森普拉制药公司 用於制备大环内酯抗菌剂的收敛方法
EP4095146A1 (en) 2013-04-04 2022-11-30 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
CA2963815A1 (en) * 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
HK1250371A1 (zh) 2015-03-25 2018-12-14 President And Fellows Of Harvard College 具有修饰的脱氧糖胺糖的大环内酯及其用途
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
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Also Published As

Publication number Publication date
EE9500080A (et) 1996-12-16
AU684939B2 (en) 1998-01-08
HU215396B (hu) 1998-12-28
BR9506147A (pt) 1996-04-16
PL311871A1 (en) 1996-03-18
UA44705C2 (uk) 2002-03-15
IS4309A (is) 1995-11-17
NO308361B1 (no) 2000-09-04
JP3000023B2 (ja) 2000-01-17
WO1995027720A1 (fr) 1995-10-19
CZ322395A3 (en) 1996-08-14
HRP950217A2 (en) 1997-08-31
IL112954A (en) 2000-07-16
IL112954A0 (en) 1995-06-29
FI955913A0 (fi) 1995-12-08
ES2189820T3 (es) 2003-07-16
RO115634B1 (ro) 2000-04-28
FI955913A7 (fi) 1995-12-08
SK154695A3 (en) 1996-10-02
PT676409E (pt) 2003-08-29
DE69529934D1 (de) 2003-04-24
MA23501A1 (fr) 1995-12-31
TW316908B (cg-RX-API-DMAC10.html) 1997-10-01
AP9500743A0 (en) 1995-07-31
US5656607A (en) 1997-08-12
MY114672A (en) 2002-12-31
EP0676409A1 (fr) 1995-10-11
BG100150A (bg) 1996-06-28
ATE234853T1 (de) 2003-04-15
ZA952059B (en) 1996-03-13
NO954942D0 (no) 1995-12-06
MD663F1 (ro) 1997-01-31
SI0676409T1 (en) 2003-06-30
HRP950217B1 (en) 2004-06-30
SK284079B6 (sk) 2004-09-08
GB2288174A (en) 1995-10-11
GEP19991836B (en) 1999-11-05
LV11182A (lv) 1996-04-20
AU2310795A (en) 1995-10-30
PL180837B1 (pl) 2001-04-30
DK0676409T3 (da) 2003-06-23
FR2718450A1 (fr) 1995-10-13
BG61916B1 (bg) 1998-09-30
EP0676409B1 (fr) 2003-03-19
JO1850B1 (en) 1995-12-27
AP587A (en) 1997-04-29
KR100317148B1 (ko) 2002-06-22
CA2164638C (fr) 2003-12-30
FI111264B (fi) 2003-06-30
NO954942L (no) 1996-02-07
CN1126997A (zh) 1996-07-17
CO4370097A1 (es) 1996-10-07
DZ1869A1 (fr) 2002-02-17
CA2164638A1 (fr) 1995-10-19
IS1865B (is) 2003-05-02
HUT73772A (en) 1996-09-30
OA10200A (fr) 1996-12-18
TNSN95026A1 (fr) 1996-02-06
EE04498B1 (et) 2005-06-15
HU9503505D0 (en) 1996-02-28
SA97170757A (ar) 2005-12-03
YU21695A (sh) 1997-12-05
MD663G2 (ro) 1997-07-31
US5760233A (en) 1998-06-02
CN1059445C (zh) 2000-12-13
FR2718450B1 (fr) 1997-01-10
LV11182B (en) 1997-04-20
DE69529934T2 (de) 2003-09-04
RU2141965C1 (ru) 1999-11-27
JPH07278177A (ja) 1995-10-24
GB9506856D0 (en) 1995-05-24
PE2896A1 (es) 1996-02-12
CZ296005B6 (cs) 2005-12-14
SV1995000018A (es) 1997-10-24
NZ284498A (en) 1997-07-27

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