WO2010019244A1 - Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom - Google Patents

Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom Download PDF

Info

Publication number
WO2010019244A1
WO2010019244A1 PCT/US2009/004637 US2009004637W WO2010019244A1 WO 2010019244 A1 WO2010019244 A1 WO 2010019244A1 US 2009004637 W US2009004637 W US 2009004637W WO 2010019244 A1 WO2010019244 A1 WO 2010019244A1
Authority
WO
WIPO (PCT)
Prior art keywords
cellulose
ionic liquid
cellulose ester
solution
regioselectively substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/004637
Other languages
English (en)
French (fr)
Inventor
Robert Thomas Hembre
Norma Lindsey Buchanan
Charles Michael Buchanan
Juanelle Little Lambert
Michael Eugene Donelson
Maryna Grigorievna Gorbunova
Thauming Kuo
Bin Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastman Chemical Co
Original Assignee
Eastman Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Chemical Co filed Critical Eastman Chemical Co
Priority to CN200980131585.8A priority Critical patent/CN102124031B/zh
Priority to EP17172680.5A priority patent/EP3239179B1/en
Priority to JP2011522997A priority patent/JP2011530643A/ja
Priority to EP09789131A priority patent/EP2313439A1/en
Publication of WO2010019244A1 publication Critical patent/WO2010019244A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B1/00—Preparatory treatment of cellulose for making derivatives thereof, e.g. pre-treatment, pre-soaking, activation
    • C08B1/003—Preparation of cellulose solutions, i.e. dopes, with different possible solvents, e.g. ionic liquids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids
    • C08B3/06—Cellulose acetate, e.g. mono-acetate, di-acetate or tri-acetate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids
    • C08B3/16—Preparation of mixed organic cellulose esters, e.g. cellulose aceto-formate or cellulose aceto-propionate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids
    • C08B3/22—Post-esterification treatments, including purification
    • C08B3/26—Isolation of the cellulose ester
    • C08B3/28—Isolation of the cellulose ester by precipitation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
    • G02B1/14—Protective coatings, e.g. hard coatings
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/30—Polarising elements
    • G02B5/3083—Birefringent or phase retarding elements
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C08J2301/08—Cellulose derivatives
    • C08J2301/14—Mixed esters

Definitions

  • the present invention relates generally to cellulose esters and/or ionic liquids.
  • One aspect of the invention concerns processes for producing cellulose esters in ionic liquids.
  • Cellulose is a ⁇ -1 ,4-linked polymer of anhydroglucose.
  • Cellulose is typically a high molecular weight, polydisperse polymer that is insoluble in water and virtually all common organic solvents.
  • Unmodified cellulose is also utilized in a variety of other applications usually as a film (e.g., cellophane), as a fiber (e.g., viscose rayon), or as a powder (e.g., microcrystalline cellulose) used in pharmaceutical applications.
  • Modified cellulose including cellulose esters, are also utilized in a wide variety of commercial applications.
  • Cellulose esters can generally be prepared by first converting cellulose to a cellulose triester, then hydrolyzing the cellulose triester in an acidic aqueous media to the desired degree of substitution ("DS"), which is the average number of ester substituents per anhydroglucose monomer. Hydrolysis of cellulose triesters containing a single type of acyl substituent under these conditions can yield a random copolymer that can consist of up to 8 different monomers depending upon the final DS.
  • DS degree of substitution
  • Ionic liquids are liquids containing substantially only anions and cations.
  • Room temperature ionic liquids are ionic liquids that are in liquid form at standard temperature and pressure.
  • the cations associated with ILs are structurally diverse, but generally contain one or more nitrogens that are part of a ring structure and can be converted to a quaternary ammonium. Examples of these cations include pyridinum, pyridazinium, pyrimidinium, pyrazinium, imidazolium, pyrazolium, oxazolium, triazolium, thiazolium, piperidinium, pyrrolidinium, quinolinium, and isoquinolinium.
  • the anions associated with ILs can also be structurally diverse and can have a significant impact on the solubility of the ILs in different media.
  • ILs containing hydrophobic anions such as hexafluorophosphates or triflimides have very low solubilities in water while ILs containing hydrophilic anions such chloride or acetate are completely miscible in water.
  • Alkyl cations are often named by the letters of the alkyl substituents and the cation, which are given within a set of brackets, followed by the abbreviation for the anion. Although not expressively written, it should be understood that the cation has a positive charge and the anion has a negative charge.
  • [BMIm]OAc indicates 1-butyl-3-methylimidazolium acetate
  • [AMIm]CI indicates 1-allyl-3-methylimidazolium chloride
  • [EMIm]OF indicates 1-ethyl-3-methylimidazolium formate.
  • a regioselectively substituted cellulose ester having a C 6 /C 3 relative degree of substitution (RDS) ratio greater than one or a C 6 IC 2 RDS ratio greater than 1.
  • a regioselectively substituted cellulose ester wherein the RDS is C 6 >C2>C3.
  • a process for making a regioselectively substituted cellulose ester comprises:
  • a process of making a regioselectively substituted cellulose ester comprises: - A -
  • photographic film, protective film, or compensation film is provided.
  • a compensation film comprising at least one regioselectively substituted cellulose ester wherein the compensation film has an R th range from about -400 to about +100 nm.
  • articles comprising the regioselectively substituted cellulose ester, such articles include, but are not limited to, thermoplastic molded products, coatings, personal care products, and drug delivery products.
  • FIG. 1 is a simplified diagram depicting the majors steps involved in a process for producing cellulose esters in ionic liquids;
  • FIG. 2 is a more detailed diagram of a process for producing cellulose esters, depicting a number of additional/optional steps for enhancing to overall efficacy and/or efficiency of the process;
  • FIG. 3 is a plot of absorbance versus time showing the dissolution of 5 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • FIG. 4 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 5 molar equivalents of acetic anhydride;
  • FIG. 5 is a plot of absorbance versus time showing the dissolution of 5 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • FIG. 6 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 3 molar equivalents of acetic anhydride at 80 0 C;
  • FIG. 7 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 3 molar equivalents of acetic anhydride and 0.2 molar equivalents of methane sulfonic acid at 80 0 C;
  • FIG. 8 is a plot of absorbance versus time showing the dissolution of 5 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • FIG. 9 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 3 molar equivalents of acetic anhydride and 0.2 molar equivalents of methane sulfonic acid at 80°C;
  • FIG. 10 is a plot of absorbance versus time showing the dissolution of 10 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • [0024JFIG. 11 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 3 molar equivalents of acetic anhydride and 0.2 molar equivalents of methane sulfonic acid at 80 0 C;
  • [0025JFIG. 12 is a plot of absorbance versus time showing the dissolution of 15 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • [0026JFIG. 13 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium chloride with 3 molar equivalents of acetic anhydride and 0.2 molar equivalents of methane sulfonic acid at 100 0 C;
  • FIG. 14 is a plot of absorbance versus time showing the dissolution of 15 weight percent cellulose in 1-butyl-3-methylimidazolium chloride
  • FIG. 15 is an NMR spectra showing the proton NMR spectra of a cellulose acetate prepared by direct acetylation
  • FIG. 16 is plot of weight percent acetic acid versus time as determined by infrared spectroscopy
  • FIG. 17 is a plot of absorbance versus time showing the removal of water from 1-butyl-3-methylimidazolium acetate prior to dissolution of cellulose;
  • FIG. 18 is a plot of absorbance versus time showing the dissolution of 10 weight percent cellulose in 1-butyl-3-methylimidazolium acetate at room temperature;
  • FIG. 19 is a plot of absorbance versus time showing the acetylation of cellulose dissolved in 1-butyl-3-methylimidazolium acetate with 5 molar equivalents of acetic anhydride and 0.1 molar equivalents of zinc acetate;
  • FIG. 20 is a spectral analysis showing infrared spectra of 1-butyl- 3-methylimidazolium formate and 1-butyl-3-methylimidazolium acetate, a spectrum after 0.5 molar equivalents of acetic anhydride has been added to the 1-butyl-3-methylimidazolium formate, and a spectrum after another 0.5 molar equivalents of acetic anhydride has been added to the 1-butyl-3- methylimidazolium formate; [0034]FIG.
  • 21 is a plot of relative concentration versus time for 1-butyl- 3-methylimidazolium formate and 1-butyl-3-methylimidazolium acetate upon first and second additions of 0.5 molar equivalents of acetic anhydride;
  • FIG. 22 is spectral analysis showing infrared spectra of 1-butyl- 3-methylimidazolium formate, 1-butyl-3-methylimidazolium formate, and a spectrum after 1 equivalent of acetic anhydride has been added to the 1-butyl- 3-methylimidazolium formate in the presence of 2 molar equivalents of methanol;
  • FIG. 23 is a plot of relative concentration versus time for 1-butyl- 3-methylimidazolium formate and 1-butyl-3-methylimidazolium acetate upon addition of 2 molar equivalents of methanol and then upon addition of 1 equivalent of acetic anhydride;
  • FIG. 24 is a plot of absorbance versus time showing the dissolution of cellulose in 1-butyl-3-methylimidazolium acetate at 80 0 C;
  • [0038JFIG. 25 is a plot of absorbance versus time showing the esterification of cellulose dissolved in 1-butyl-3-methylimidazolium acetate
  • FIG. 26 is a spectral analysis showing the ring proton resonances for cellulose acetates prepared from cellulose dissolved in 1- butyl-3-methylimidazolium acetate (top spectrum), and the ring proton resonances for cellulose acetates prepared from cellulose dissolved in 1- butyl-3-methylimidazolium chloride (bottom spectrum); and
  • FIG. 27 is a spectral analysis showing the ring proton resonances for cellulose acetates prepared from cellulose dissolved in 1- butyl-3-methylimidazolium acetate after water addition (top spectrum) and before water addition (bottom spectrum).
  • FIG. 28 compares the viscosities of solutions of cellulose (5 wt%) dissolved in [BMIm]CI, [BMIm]CI + 5 wt% acetic acid, and [BMIm]CI + 10 wt% acetic acid.
  • FIG. 29 compares the viscosities of solutions of cellulose contact mixtures without a cosolvent and with methyl ethyl ketone as a cosolvent.
  • FIG 30 shows a plot of absorbance for an infrared band at 1212 cm “1 (propionate ester and propionic acid) versus contact time during esterification (3.7 eq propionic anhydride) of cellulose dissolved either in [BMIm]OPr or [BMIm]OPr + 11.9 wt% propionic acid.
  • FIG. 31 shows a plot of absorbance versus time for a staged addition of Pr 2 O (1 st ) and Ac 2 O (2 nd ) illustrating the esterification cellulose (1756, 1233, 1212 cm '1 ), the consumption of anhydride (1815 cm “1 ), and the coproduction of carboxylic acid (1706 cm “1 ) during the experiment.
  • FIG. 32 shows the proton NMR spectra for the samples removed during the contact period following the staged addition of Pr 2 O (1 st ) and Ac 2 O (2 nd ).
  • FIG. 33 shows the carbonyl region in the 13 C NMR spectra of a sample following the staged addition of Pr 2 O (1 st ) and Ac 2 O (2 nd ) [series 1], following the staged addition of Ac 2 O (1 st ) and Pr 2 O (2 nd ) [series 2], and following the mixed addition of Pr 2 O and Ac 2 O [series 3].
  • FIG. 34 shows a plot of DS versus glass transition temperature (Tg) for the cellulose acetate propionates prepared by staged addition of Pr 2 O (1 st ) and Ac 2 O (2 nd ) [series 1], by staged addition Of Ac 2 O (1 st ) and Pr 2 O (2 nd ) [series 2], and by mixed addition of Pr 2 O and Ac 2 O [series 3].
  • FIG. 35 shows a plot of DS propionate versus glass transition temperature (Tg) for the cellulose acetate propionates prepared by staged addition of Pr 2 O (1 st ) and Ac 2 O (2 nd ) [series 1], by staged addition Of Ac 2 O (1 st ) and Pr 2 O (2 nd ) [series 2], and by mixed addition of Pr 2 O and Ac 2 O [series 3].
  • FIG. 1 depicts a simplified system for producing cellulose esters.
  • the system of FIG. 1 generally includes a dissolution zone 20, an esterification zone 40, a cellulose ester recovery/treatment zone 50, and an ionic liquid recovery/treatment zone 60.
  • cellulose and an ionic liquid can be fed to dissolution zone 20 via lines 62 and 64, respectively.
  • the cellulose can be dissolved to form an initial cellulose solution comprising the cellulose and the ionic liquid.
  • the initial cellulose solution can then be transported to esterification zone 40.
  • esterification zone 40 a reaction medium comprising the dissolved cellulose can be subjected to reaction conditions sufficient to at least partially esterify the cellulose, thereby producing an initial cellulose ester.
  • An acylating reagent can be added to esterification zone 40 and/or dissolution zone 20 to help facilitate esterification of the dissolved cellulose in esterification zone 40.
  • an esterified medium can be withdrawn from esterification zone 40 via line 80 and thereafter transported to cellulose ester recovery/treatment zone 50 where the initial cellulose ester can be recovered and treated to thereby produce a final cellulose ester that exits recovery/treatment zone 50 via line 90.
  • a recycle stream is produced from cellulose ester recovery/treatment zone 50 via line 86.
  • This recycle stream can comprise an altered ionic liquid derived from the ionic liquid originally introduced into dissolution zone 20.
  • the recycle stream in line 86 can also include various other compounds including byproducts of reactions occurring in upstream zones 20,40,50 or additives employed in upstream zones 20,40,50.
  • the recycle stream in line 86 can be introduced into ionic liquid recovery/treatment zone 60 where it can be subjected to separation and/or reformation processes.
  • a recycled ionic liquid can be produced from ionic liquid recovery/treatment zone 60 and can be routed back to dissolution zone 20 via line 70. Additional details of the streams, reactions, and steps involved in the cellulose ester production system of FIG. 1 are provided immediately below.
  • the cellulose fed to dissolution zone 20 via line 62 can be any cellulose known in the art that is suitable for use in the production of cellulose esters.
  • the cellulose suitable for use in the present invention can be obtained from soft or hard woods in the form of wood pulps, or from annual plants such as cotton or corn.
  • the cellulose can be a ⁇ -1 ,4- linked polymer comprising a plurality of anhydroglucose monomer units.
  • the cellulose suitable for use in the present invention can generally comprise the following structure:
  • the cellulose employed in the present invention can have an ⁇ - cellulose content of at least about 90 percent by weight, at least about 95 percent by weight, or at least 98 percent by weight.
  • the cellulose fed to dissolution zone 20 via line 62 can have a degree of polymerization ("DP") of at least about 10, at least about 250, at least about 1 ,000, or at least 5,000.
  • DP degree of polymerization
  • the cellulose can have a weight average molecular weight in the range of from about 1 ,500 to about 850,000, in the range of from about 40,000 to about 200,000, or in the range of from 55,000 to about 160,000.
  • the cellulose suitable for use in the present invention can be in the form of a sheet, a hammer milled sheet, fiber, or powder.
  • the cellulose can be a powder having an average particle size of less than about 500 micrometers (" ⁇ m"), less than about 400 ⁇ m, or less than 300 ⁇ m.
  • the ionic liquid fed to dissolution zone 20 via line 64 can be any ionic liquid capable of at least partially dissolving cellulose.
  • the term "ionic liquid” shall denote any substance containing substantially only ions, and which has a melting point at a temperature of 200 0 C or less.
  • the ionic liquid suitable for use in the present invention can be a cellulose dissolving ionic liquid.
  • the term "cellulose dissolving ionic liquid” shall denote any ionic liquid capable of dissolving cellulose in an amount sufficient to create an at least 0.1 weight percent cellulose solution.
  • the ionic liquid fed to dissolution zone 20 via line 64 can have a temperature at least 10 0 C above the melting point of the ionic liquid. In another embodiment, the ionic liquid can have a temperature in the range of from about 0 to about 100 0 C, in the range of from about 20 to about 80 0 C, or in the range of from 25 to 50 0 C. [0055] In one embodiment, the ionic liquid fed to dissolution zone 20 via line 64 can comprise water, nitrogen-containing bases, alcohol, or carboxylic acid.
  • the ionic liquid in line 64 can comprise less than about 15 weight percent of each of water, nitrogen-containing bases, alcohol, and carboxylic acid; less than about 5 weight percent of each of water, nitrogen-containing bases, alcohol, and carboxylic acid; or less than 2 weight percent of each of water, nitrogen-containing bases, alcohol, and carboxylic acid.
  • an ionic liquid comprises ions. These ions include both cations (i.e., positively charged ions) and anions (i.e., negatively charged ions).
  • the cations of the ionic liquid suitable for use in the present invention can include, but are not limited to, imidazolium, pyrazolium, oxazolium, 1 ,2,4-triazolium, 1 ,2,3-triazolium, and/or thiazolium cations, which correspond to the following structures:
  • Ri and R 2 can independently be a Ci to Cs alkyl group, a C 2 to Ce alkenyl group, or a Ci to Cs alkoxyalkyl group.
  • R 3 , R 4 , and R 5 can independently be a hydrido, a Ci to Cs alkyl group, a C 2 to Ce alkenyl group, a Ci to Ce alkoxyalkyl group, or a Ci to Ce alkoxy group.
  • the cation of the ionic liquid used in the present invention can comprise an alkyl substituted imidazolium cation, where R 1 is a Ci to C 4 alkyl group, and R 2 is a different Ci to C 4 alkyl group.
  • the cellulose dissolving ionic liquid can be a carboxylated ionic liquid.
  • carboxylated ionic liquid shall denote any ionic liquid comprising one or more carboxylate anions.
  • Carboxylate anions suitable for use in the carboxylated ionic liquids of the present invention include, but are not limited to, Ci to C2 0 straight- or branched-chain carboxylate or substituted carboxylate anions.
  • carboxylate anions for use in the carboxylated ionic liquid include, but are not limited to, formate, acetate, propionate, butyrate, valerate, hexanoate, lactate, oxalate, or chloro-, bromo-, fluoro-substituted acetate, propionate, or butyrate and the like.
  • the anion of the carboxylated ionic liquid can be a C 2 to C 6 straight-chain carboxylate.
  • the anion can be acetate, propionate, butyrate, or a mixture of acetate, propionate, and/or butyrate.
  • carboxylated ionic liquids suitable for use in the present invention include, but are not limited to, 1-ethyl-3-methylimidazolium acetate, 1-ethyl-3-methylimidazolium propionate, 1-ethyl-3-methylimidazolium butyrate, 1-butyl-3-methylimidazolium acetate, 1-butyl-3-methylimidazolium propionate, 1-butyl-3-methylimidazolium butyrate, or mixtures thereof.
  • the carboxylated ionic liquid can contain sulfur in an amount less than 200 parts per million by weight ("ppmw"), less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw based on the total ion content of the carboxylated ionic liquid. Additionally, the carboxylated ionic liquid can contain a total halide content of less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw based on the total ion content of the carboxylated ionic liquid.
  • the carboxylated ionic liquid can contain a total metal content of less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw based on the total ion content of the carboxylated ionic liquid.
  • carboxylated ionic liquid can contain transition metals in an amount less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw.
  • Sulfur, halide, and metal content of the carboxylated ionic liquid can be determined by x-ray fluorescence ("XRF") spectroscopy.
  • the carboxylated ionic liquid of the present invention can be formed by any process known in the art for making ionic liquids having at least one carboxylate anion.
  • the carboxylated ionic liquid of the present invention can be formed by first forming an intermediate ionic liquid.
  • the intermediate ionic liquid can be any known ionic liquid that can participate in an anion exchange reaction.
  • the intermediate ionic liquid can comprise a plurality of cations such as, for example, imidazolium, pyrazolium, oxazolium, 1 ,2,4-triazolium, 1 ,2,3-triazolium, and/or thiazolium cations, which correspond to the following structures:
  • Ri and R 2 can independently be a Ci to C 8 alkyl group, a C 2 to C 8 alkenyl group, or a Ci to C 8 alkoxyalkyl group.
  • R 3 , R 4 , and R 5 can independently be a hydrido, a C 1 to C 8 alkyl group, a C 2 to C 8 alkenyl group, a Ci to C 8 alkoxyalkyl group, or a Ci to C 8 alkoxy group.
  • the cation of the intermediate ionic liquid used in the present invention can comprise an alkyl substituted imidazolium cation, where Ri is a Ci to C 4 alkyl group, and R 2 is a different C 1 to C 4 alkyl group.
  • the cation of the intermediate ionic liquid can comprise 1-ethyl- 3-methylimidazolium or 1-butyl-3-methylimidazolium.
  • the intermediate ionic liquid can comprise a plurality of anions.
  • the intermediate ionic liquid can comprise a plurality of carboxylate anions, such as, for example, formate, acetate, and/or propionate anions.
  • the intermediate ionic liquid can comprise an alkyl amine formate.
  • the amine cation of the alkyl amine formate can comprise any of the above-described substituted or unsubstituted imidazolium, pyrazolium, oxazolium, 1 ,2,4-triazolium, 1 ,2,3-triazolium, and/or thiazolium cations.
  • the amine of the alkyl amine formate can be an alkyl substituted imidazolium, alkyl substituted pyrazolium, alkyl substituted oxazolium, alkyl substituted triazolium, alkyl substituted thiazolium, and mixtures thereof.
  • the amine of the alkyl amine formate can be an alkyl substituted imidazolium.
  • alkyl amine formates suitable for use in the present invention include, but are not limited to, 1-methyl-3-methylimidazolium formate, 1-ethyl-3-methylimidazolium formate, 1-propyl-3-methylimidazolium formate, 1-butyl-3-methylimidazolium formate, 1-pentyl-3-methylimidazolium formate, and/or 1-octyl-3- methylimidazolium formate.
  • the intermediate ionic liquid useful in the present invention can be formed by contacting at least one amine with at least one alkyl formate.
  • Amines suitable for use in the present invention include, but are not limited to, substituted or unsubstituted imidazoles, pyrazoles, oxazoles, triazoles, and/or thiazoles.
  • the alkyl amine formate can be formed by contacting at least one alkyl substituted imidazole with at least one alkyl formate.
  • alkyl substituted imidazoles suitable for use in forming the intermediate ionic liquid include, but are not limited to, 1-methylimidazole, 1-ethylimidazole, 1-propylimidazole, 1-butylimidazole, 1-hexylimidazole, and/or 1-octylimidazole.
  • alkyl formates suitable for use in forming the intermediate ionic liquid include, but are not limited to, methyl formate, ethyl formate, propyl formate, isopropyl formate, butyl formate, isobutyl formate, tert-butyl formate, hexyl formate, octyl formate, and the like.
  • the alkyl formate used in forming the intermediate ionic liquid can comprise methyl formate.
  • the intermediate ionic liquid can be contacted with one or more carboxylate anion donors at a contact time, pressure, and temperature sufficient to cause the at least partial conversion of the intermediate ionic liquid to at least one of the above-mentioned carboxylated ionic liquids.
  • Such interconversion can be accomplished via anion exchange between the carboxylate anion donor and the intermediate ionic liquid.
  • at least a portion of the formate of the alkyl amine formate can be replaced via anion exchange with a carboxylate anion originating from one or more carboxylate anion donors.
  • Carboxylate anion donors useful in the present invention can include any substance capable of donating at least one carboxylate anion.
  • carboxylate anion donors suitable for use in the present invention include, but are not limited to, carboxylic acids, anhydrides, and/or alkyl carboxylates.
  • the carboxylate anion donor can comprise one or more C 2 to C 20 straight- or branched-chain alkyl or aryl carboxylic acids, anhydrides, or methyl esters.
  • the carboxylate anion donor can comprise one or more C 2 to Ci 2 straight-chain alkyl carboxylic acids, anhydrides, or methyl esters.
  • the carboxylate anion donor can comprise one or more C 2 to C 4 straight-chain alkyl carboxylic acids, anhydrides, or methyl esters.
  • the carboxylate anion donor can comprise at least one anhydride, which can comprise acetic anhydride, propionic anhydride, butyric anhydride, isobutyric anhydride, valeric anhydride, hexanoic anhydride, 2-ethylhexanoic anhydride, nonanoic anhydride, lauric anhydride, palmitic anhydride, stearic anhydride, benzoic anhydride, substituted benzoic anhydrides, phthalic anhydride, isophthalic anhydride, and mixtures thereof.
  • the amount of carboxylate anion donor useful in the present invention can be any amount suitable to convert at least a portion of the intermediate ionic liquid to a carboxylated ionic liquid.
  • the carboxylate anion donor can be present in a molar ratio with the intermediate ionic liquid in the range of from about 1 :1 to about 20:1 carboxylate anion donor-to-intermediate ionic liquid anion content, or in the range of from 1 :1 to 6:1 carboxylate anion donor-to-intermediate ionic liquid anion content.
  • the carboxylate anion donor when alkyl amine formate is present as the intermediate ionic liquids, can be present in an amount in the range of from 1 to 20 molar equivalents per alkyl amine formate, or in the range of from 1 to 6 molar equivalents per alkyl amine formate.
  • the anion exchange between the intermediate ionic liquid and the carboxylate anion donor can be accomplished in the presence of at least one alcohol.
  • Alcohols useful in the present invention include, but are not limited to, alkyl or aryl alcohols such as methanol, ethanol, n-propanol, i- propanol, n-butanol, i-butanol, t-butanol, phenol, and the like.
  • the alcohol can be methanol.
  • the amount of alcohol present in the contact mixture during interconversion of the intermediate ionic liquid can be in the range of from about 0.01 to about 20 molar equivalents of the ionic liquid, or in the range of from 1 to 10 molar equivalents of the ionic liquid.
  • water can be present in the contact mixture during the anion exchange between the intermediate ionic liquid and the carboxylate anion donor.
  • the amount of water present in the contact mixture during interconversion of the intermediate ionic liquid can be in the range of from about 0.01 to about 20 molar equivalents of the ionic liquid, or in the range of from 1 to 10 molar equivalents of the ionic liquid.
  • the interconversion of the intermediate ionic liquid to the carboxylated ionic liquid can be performed at a contact time, pressure, and temperature sufficient to cause the at least partial conversion of the intermediate ionic liquid to the carboxylated ionic liquid.
  • the interconversion can be performed for a time in the range of from about 1 minute to about 24 hours, or in the range of from 30 minutes to 18 hours.
  • the interconversion can be performed at a pressure up to 21 ,000 kPa, or up to 10,000 kPa.
  • the interconversion can be performed at a pressure in the range of from about 100 to about 21 ,000 kPa, or in the range of from 100 to 10,000 kPa.
  • the interconversion can be performed at a temperature in the range of from about 0 to about 200 0 C, or in the range of from 25 to 170 0 C.
  • the resulting carboxylated ionic liquid can comprise carboxylate anions comprising substituted or non-substituted Ci to C2 0 straight- or branched-chain carboxylate anions.
  • the carboxylate anion can comprise a C 2 to Ce straight-chain carboxylate anion.
  • the carboxylated ionic liquid can comprise carboxylate anions such as, for example, formate, acetate, propionate, butyrate, valerate, hexanoate, lactate, and/or oxalate.
  • the carboxylated ionic liquid can comprise at least 50 percent carboxylate anions, at least 70 percent carboxylate anions, or at least 90 percent carboxylate anions. In another embodiment, the carboxylated ionic liquid can comprise at least 50 percent acetate anions, at least 70 percent acetate anions, or at least 90 percent acetate anions.
  • the above-mentioned cellulose dissolving ionic liquid can be a halide ionic liquid.
  • halide ionic liquid shall denote any ionic liquid that contains at least one halide anion.
  • the halide anion of the halide ionic liquid can be fluoride, chloride, bromide, and/or iodide.
  • the halide anion can be chloride and/or bromide.
  • the cation of the cellulose dissolving ionic liquid can comprise, but is not limited to, imidazolium, pyrazolium, oxazolium, 1 ,2,4-triazolium, 1 ,2,3-triazolium, and/or thiazolium cations. Any method known in the art suitable for making a halide ionic liquid can be employed in the present invention.
  • halide ionic liquids suitable for use in the present invention include, but are not limited to, 1-butyl-3-methylimidazolium chloride, 1-propyl-3-methylimidazolium chloride, 1-ethyl-3-methylimidazolium chloride, 1-allyl-3-methylimidazolium chloride, or mixtures thereof.
  • the weight percent of the amount of cellulose fed to dissolution zone 20 to the cumulative amount of ionic liquid (including recycled ionic liquid) fed to dissolution zone 20 can be in the range of from about 1 to about 40 weight percent, in the range of from about 5 to about 25 weight percent, or in the range of from 10 to 20 weight percent based on the combined weight of cellulose and ionic liquid.
  • the resulting medium formed in dissolution zone 20 can comprise other components, such as, for example, water, alcohol, acylating reagent, and/or carboxylic acids.
  • the medium formed in dissolution zone 20 can comprise water in an amount in the range of from about 0.001 to about 200 weight percent, in the range of from about 1 to about 100 weight percent, or in the range of from 5 to 15 weight percent based on the entire weight of the medium. Additionally, the medium formed in dissolution zone 20 can comprise a combined concentration of alcohol in an amount in the range of from about 0.001 to about 200 weight percent, in the range of from about 1 to about 100 weight percent, or in the range of from 5 to 15 weight percent based on the entire weight of the medium.
  • the medium formed in dissolution zone 20 can optionally comprise one or more carboxylic acids.
  • the medium formed in dissolution zone 20 can comprise a total concentration of carboxylic acids in the range of from about 0.01 to about 25 weight percent, in the range of from about 0.05 to about 15 weight percent, or in the range of from 0.1 to 5 weight percent based on the total concentration of ionic liquid in the medium formed in dissolution zone 20.
  • carboxylic acids useful in this embodiment include, but are not limited to, acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, hexanoic acid, 2-ethylhexanoic acid, nonanoic acid, lauric acid, palmitic acid, stearic acid, benzoic acid, substituted benzoic acids, phthalic acid, and isophthalic acid.
  • the carboxylic acid in the medium formed in dissolution zone 20 can comprise acetic acid, propionic acid, and/or butyric acid. [0076]As is described in more detail below with reference to FIG.
  • At least a portion of the carboxylic acids present in the medium formed in dissolution zone 20 can originate from a recycled carboxylated ionic liquid introduced via line 70.
  • carboxylic acid in the medium formed in dissolution zone 20 can reduce the viscosity of the cellulose/ionic liquid solution, thereby enabling easier processing of the solution.
  • the presence of carboxylic acid in the medium in dissolution zone 20 appears to reduce the melting points of the ionic liquids employed, thereby allowing processing of the ionic liquids at lower temperatures than predicted.
  • the medium formed in dissolution zone 20 can optionally comprise an acylating reagent, as is discussed in more detail below.
  • the optional acylating reagent can be introduced into dissolution zone 20 via line 78.
  • the medium formed in dissolution zone 20 can comprise acylating reagent in an amount in the range of from about 0.01 molar equivalents to about 20 molar equivalents, in the range of from about 0.5 molar equivalents to about 10 molar equivalents, or in the range of from 1.8 molar equivalents to about 4 molar equivalents based on the total amount of cellulose in the medium in dissolution zone 20.
  • the medium formed in dissolution zone 20 can also comprise recycled ionic liquid, as is discussed in more detail below with reference to FIG. 2.
  • the recycled ionic liquid can be introduced into dissolution zone 20 via line 70.
  • the medium formed in dissolution zone 20 can comprise recycled ionic liquid in an amount in the range of from about 0.01 to about 99.99 weight percent, in the range of from about 10 to about 99 weight percent, or in the range of from 90 to 98 weight percent based on the total amount of ionic liquid in dissolution zone 20.
  • the medium can optionally comprise immiscible or substantially immiscible co-solvents.
  • co-solvents can comprise one or more co-solvents that are immiscible or sparingly soluble with the cellulose-ionic liquid mixture.
  • an immiscible or sparingly soluble co-solvent does not cause precipitation of the cellulose upon contacting the cellulose-ionic liquid mixture.
  • the cellulose upon contact with an acylating reagent, as will be discussed in more detail below, the cellulose can be estehfied which can change the solubility of the now cellulose ester-ionic liquid solution with respect to the formerly immiscible or sparingly soluble co-solvent.
  • the contact mixture can become a single phase or highly dispersed mixture of cellulose ester-ionic liquid in the co-solvent.
  • the resulting single phase or dispersed phase has much lower solution viscosity than the initial cellulose- ionic liquid solution.
  • Immiscible or sparingly soluble co-solvents suitable for use in the present invention can comprise alkyl or aryl esters, ketones, alkyl halides, hydrophobic ionic liquids, and the like.
  • Specific examples of immiscible or sparingly soluble co-solvents include, but are not limited to, methyl acetate, ethyl acetate, isopropyl acetate, methyl propionate, methyl butyrate, acetone, methyl ethyl ketone, chloroform, methylene chloride, alkyl immidazolium hexafluorophosphate, alkyl immidazolium triflimide, and the like.
  • the immiscible or sparingly soluble co-solvents can comprise methyl acetate, methyl propionate, methyl butyrate, methyl ethyl ketone, and/or methylene chloride.
  • the weight ratio of immiscible or sparingly soluble co-solvents to cellulose-ionic liquid mixture can be in the range of from about 1 :20 to about 20:1. or in the range of from 1 :5 to 5:1.
  • the cellulose entering dissolution zone 20 via line 62 can initially be dispersed in the ionic liquid.
  • Dispersion of the cellulose in the ionic liquid can be achieved by any mixing means known in the art.
  • dispersion of the cellulose can be achieved by mechanical mixing, such as mixing by one or more mechanical homogenizers.
  • dissolution of the cellulose in dissolution zone 20, along with removal of at least a portion of any volatile components in the mixture can be achieved using any method known in the art. For example, dissolution of the cellulose can be achieved by lowering the pressure and/or raising the temperature of the cellulose/ionic liquid dispersion initially formed in dissolution zone 20.
  • the pressure can be lowered in dissolution zone 20.
  • the pressure in dissolution zone 20 can be lowered to less than about 100 millimeters mercury ("mm Hg"), or less than 50 mm Hg.
  • the cellulose/ionic liquid dispersion can be heated to a temperature in the range of from about 60 to about 100 0 C, or in the range of from 70 to about 85°C.
  • the resulting solution can be maintained at the above-described temperatures and pressures for a time in the range of from about 0 to about 100 hours, or in the range of from about 1 to about 4 hours.
  • the cellulose solution formed in dissolution zone 20 can comprise cellulose in an amount in the range of from about 1 to about 40 weight percent, or in the range of from 5 to 20 weight percent, based on the entire weight of the solution. In another embodiment, the cellulose solution formed in dissolution zone 20 can comprise dissolved cellulose in an amount of at least 10 weight percent based on the entire weight of the solution.
  • At least a portion of the resulting cellulose solution can be removed from dissolution zone 20 via line 66 and routed to esterification zone 40.
  • at least one acylating reagent can be introduced into esterification zone 40 to esterify at least a portion of the cellulose.
  • at least one acylating reagent can be introduced into dissolution zone 20.
  • the acylating reagent can be added after the cellulose has been dissolved in the ionic liquid.
  • at least a portion of the acylating reagent can be added to the ionic liquids prior to dissolution of the cellulose in the ionic liquid. Regardless of where the acylating reagent is added, at least a portion of the cellulose in esterification zone 40 can undergo esterification subsequent to being contacted with the acylating reagent.
  • acylating reagent shall denote any chemical compound capable of donating at least one acyl group to a cellulose.
  • acyl group shall denote any organic radical derived from an organic acid by the removal of a hydroxyl group.
  • Acylating reagents useful in the present invention can be one or more Ci to C 2O straight- or branched-chain alkyl or aryl carboxylic anhydrides, carboxylic acid halides, diketene, or acetoacetic acid esters.
  • carboxylic anhydrides suitable for use as acylating reagents in the present invention include, but are not limited to, acetic anhydride, propionic anhydride, butyric anhydride, isobutyric anhydride, valeric anhydride, hexanoic anhydride, 2- ethylhexanoic anhydride, nonanoic anhydride, lauric anhydride, palmitic anhydride, stearic anhydride, benzoic anhydride, substituted benzoic anhydrides, phthalic anhydride, and isophthalic anhydride.
  • carboxylic acid halides suitable for use as acylating reagents in the present invention include, but are not limited to, acetyl, propionyl, butyryl, hexanoyl, 2- ethylhexanoyl, lauroyl, palmitoyl, benzoyl, substituted benzoyl, and stearoyl chlorides.
  • acetoacetic acid esters suitable for use as acylating reagents in the present invention include, but are not limited to, methyl acetoacetate, ethyl acetoacetate, propyl acetoacetate, butyl acetoacetate, and tert-butyl acetoacetate.
  • the acylating reagents can be C2 to C 9 straight- or branched-chain alkyl carboxylic anhydrides selected from the group consisting of acetic anhydride, propionic anhydride, butyric anhydride, 2-ethylhexanoic anhydride, and nonanoic anhydride.
  • the reaction medium formed in esterification zone 40 can comprise cellulose in an amount in the range of from about 1 to about 40 weight percent, in the range of from about 5 to about 25 weight percent, or in the range of from 10 to 20 weight percent, based on the weight of the ionic liquid in the reaction medium. Additionally, the reaction medium formed in esterification zone 40 can comprise ionic liquid in an amount in the range of from about 20 to about 98 weight percent, in the range of from about 30 to about 95 weight percent, or in the range of from 50 to 90 weight percent based on the total weight of the reaction medium.
  • reaction medium formed in esterification zone 40 can comprise acylating reagent in an amount in the range of from about 1 to about 50 weight percent, in the range of from about 5 to about 30 weight percent, or in the range of from 10 to 20 weight percent based on the total weight of the reaction medium.
  • the reaction medium formed in esterification zone 40 can have a cumulative concentration of nitrogen containing bases and carboxylic acids in an amount less than 15 weight percent, less than 5 weight percent, or less than 2 weight percent.
  • the weight ratio of cellulose-to-acylating reagent in esterification zone 40 can be in the range of from about 90:10 to about 10:90, in the range of from about 60:40 to about 25:75, or in the range of from 45:55 to 35:65.
  • the acylating reagent can be present in esterification zone 40 in an amount less than 5, less than 4, less than 3, or less than 2.7 molar equivalents per anhydroglucose unit.
  • acylating reagent when a halide ionic liquid is employed as the cellulose dissolving ionic liquid, a limited excess of acylating reagent can be employed in the esterification of the cellulose to achieve a cellulose ester with a particular DS.
  • less than 20 percent molar excess, less than 10 percent molar excess, less than 5 percent molar excess, or less than 1 percent excess of acylating reagent can be employed during esterification.
  • the 2 or more acylating reagents can be added as a mixture or the addition can be staged.
  • the acylating reagents are added consecutively.
  • at least about 80 molar percent of the first acylating reagent is allowed to react with the cellulose prior to adding the next acylating reagent.
  • one or more catalysts can be introduced into esterification zone 40 to aid in esterification of the cellulose.
  • the catalyst employed in the present invention can be any catalyst that increases the rate of esterification in esterification zone 40.
  • catalysts suitable for use in the present invention include, but are not limited to, protic acids of the type sulfuric acid, alkyl sulfonic acids, aryl sulfonic acids, functional ionic liquids, and weak Lewis acids of the type MXn, where M is a transition metal exemplified by B, Al, Fe, Ga, Sb, Sn, As, Zn, Mg, or Hg, and X is halogen, carboxylate, sulfonate, alkoxide, alkyl, or aryl.
  • the catalyst is a protic acid.
  • the protic acid catalysts can have a pKa in the range of from about -5 to about 10, or in the range of from -2.5 to 2.0.
  • suitable protic acid catalysts include methane sulfonic acid ("MSA"), p-toluene sulfonic acid, and the like.
  • the one or more catalysts can be Lewis acids. Examples of Lewis acids suitable for use as catalysts include ZnCI2, Zn(OAc)2, and the like.
  • the catalyst can be added to the cellulose solution prior to adding the acylating reagent. In another embodiment the catalyst can be added to the cellulose solution as a mixture with the acylating reagent.
  • functional ionic liquids can be employed as catalysts during esterification of the cellulose.
  • Functional ionic liquids are ionic liquids containing specific functional groups, such as hydrogen sulfonate, alkyl or aryl sulfonates, and carboxylates, that effectively catalyze the esterification of cellulose by the acylating reagent.
  • Examples of functional ionic liquids include 1-alkyl-3-methylimidazolium hydrogen sulfate, methyl sulfonate, tosylate, and trifluoroacetate, where the alkyl can be a Ci to C-io straight-chain alkyl group.
  • suitable functional ionic liquids for use in the present invention are those in which the functional group is covalently linked to the cation.
  • functional ionic liquids can be ionic liquids containing functional groups, and are capable of catalyzing the esterification of cellulose with an acylating reagent.
  • a covalently-linked functional ionic liquid suitable for use in the present invention includes, but is not limited to, the following structure:
  • R-i, R2, R3, R 4 , R5 groups are replaced with the group (CHX) n Y, where X is hydrogen or halide, n is an integer in the range of from 1 to 10, and Y is sulfonic or carboxylate and the remainder R 1 , R2, R3, R 4 , R 5 groups are those previously described in relation to the cations suitable for use as the cellulose dissolving ionic liquid.
  • Examples of cations suitable for use in the functional ionic liquids to be used in the present invention include, but are not limited to, 1-alkyl-3-(1-carboxy-2,2-difluoroethyl)imidazolium, 1- alkyl-3-(1 -carboxy-2,2-difluoropropyl)imidazolium, 1 -alkyl-3-(1 -carboxy-2,2- difluoro-butyl)imidazolium, 1 -alkyl-3-(1 -carboxy-2,2-difluorohexyl)imidazolium, 1-alkyl-3-(1-sulfonylethyl)imidazolium, 1-alkyl-3-(1-sulfonylpropyl)imidazolium, 1-alkyl-3-(1-sulfonylbutyl)imidazolium, and 1-alkyl-3-(1- sulfonylhex
  • the amount of catalyst used to catalyze the esterification of cellulose may vary depending upon the type of catalyst employed, the type of acylating reagent employed, the type of ionic liquid, the contact temperature, and the contact time. Thus, a broad concentration of catalyst employed is contemplated by the present invention. In one embodiment, the amount of catalyst employed in esterification zone 40 can be in the range of from about 0.01 to about 30 mol percent catalyst per anhydroglucose unit ("AGU"), in the range of from about 0.05 to about 10 mol percent catalyst per AGL ) , or in the range of from 0.1 to 5 mol percent catalyst per AGU.
  • AGU anhydroglucose unit
  • the amount of catalyst employed can be less than 30 mol percent catalyst per AGU, less than 10 mol percent catalyst per AGU, less than 5 mol percent catalyst per AGU, or less than 1 mol percent catalyst per AGU.
  • the amount of binary component employed can be in the range of from about 0.01 to about 100 mol percent per AGU, in the range of from about 0.05 to about 20 mol percent per AGU, or in the range of from 0.1 to 5 mol percent per AGU.
  • the inventors have discovered a number of surprising and unpredictable advantages apparently associated with employing a catalyst as a binary component during the esterification of cellulose.
  • the inclusion of a binary component can accelerate the rate of esterification.
  • the binary component can also serve to improve solution and product color, prevent gellation of the esterification mixture, provide increased DS values in relation to the amount of acylating reagent employed, and/or help to decrease the molecular weight of the cellulose ester product.
  • the use of a binary component acts to change the network structure of the ionic liquid containing the dissolved cellulose ester. This change in network structure may lead to the observed surprising and unpredicted advantages of using the binary component.
  • esterification reaction zone 40 At least a portion of the cellulose can undergo an esterification reaction in esterification zone 40.
  • the esterification reaction carried out in esterification zone 40 can operate to convert at least a portion of the hydroxyl groups contained on the cellulose to ester groups, thereby forming a cellulose ester.
  • cellulose ester shall denote a cellulose polymer having at least one ester substituent.
  • '"mixed cellulose ester shall denote a cellulose ester having at least two different ester substituents on a single cellulose ester polymer chain.
  • at least a portion of the ester groups on the resulting cellulose ester can originate from the above-described acylating reagent.
  • the cellulose esters thus prepared can comprise the following structure:
  • R 2 , R 3 , and RQ can independently be hydrogen, so long as R 2 , R3, and R 6 are not all hydrogen simultaneously, or a Ci to C 20 straight- or branched- chain alkyl or aryl groups bound to the cellulose via an ester linkage.
  • one or more of the ester groups on the resulting cellulose ester can originate from the ionic liquid in which the cellulose is dissolved.
  • the amount of ester groups on the resulting cellulose ester that originate from the carboxylated ionic liquid can be at least 10 percent, at least 25 percent, at least 50 percent, or at least 75 percent.
  • the ester group on the cellulose ester originating from the carboxylated ionic liquid can be a different ester group than the ester group on the cellulose ester that originates from the acylating reagent.
  • an anion exchange can occur such that a carboxylate ion originating from the acylating reagent replaces at least a portion of the carboxylate anions in the carboxylated ionic liquid, thereby creating a substituted ionic liquid.
  • the substituted ionic liquid can comprise at least two different types of carboxylate anions.
  • the carboxylate anion from the carboxylated ionic liquid comprises a different acyl group than is found on the acylating reagent, at least two different acyl groups are available for esterification of the cellulose.
  • R3, R6 are hydrogen, acetate, propionate.
  • contacting a solution of cellulose dissolved in [BMIm]acetate with a propionic anhydride can result in the formation of a cellulose ester comprising both acetate ester substituents and propionate ester substituents.
  • a cellulose ester comprising both acetate ester substituents and propionate ester substituents.
  • at least a portion of the ester groups on the cellulose ester can originate from the ionic liquid, and at least a portion of the ester groups can originate from the acylating reagent.
  • at least one of the ester groups donated by the ionic liquid can be an acyl group. In one embodiment, all of the ester groups donated by the ionic liquid can be acyl groups.
  • the cellulose ester prepared by methods of the present invention can be a mixed cellulose ester.
  • the mixed cellulose ester of the present invention can comprise a plurality of first pendant acyl groups and a plurality of second acyl groups, where the first pendant acyl groups originate from the ionic liquid, and the second pendant acyl groups originate from the acylating reagent.
  • the mixed cellulose ester can comprise a molar ratio of at least two different acyl pendant groups in the range of from about 1 :10 to about 10:1 , in the range of from about 2:8 to about 8:2, or in the range of from 3:7 to 7:3.
  • the first and second pendant acyl groups can comprise acetyl, propionyl, and/or butyryl groups.
  • At least one of the first pendant acyl groups can be donated by the ionic liquid or at least one of the second pendant acyl groups can be donated by the ionic liquid.
  • the term "donated,” with respect to esterification shall denote a direct transfer of an acyl group.
  • the term "originated,” with respect to esterification can signify either a direct transfer or an indirect transfer of an acyl group.
  • at least 50 percent of the above-mentioned first pendant acyl groups can be donated by the ionic liquid, or at least 50 percent of the second pendant acyl groups can be donated by the ionic liquid.
  • at least 10 percent, at least 25 percent, at least 50 percent, or at least 75 percent of all of the pendant acyl groups on the resulting cellulose ester can result from donation of an acyl group by the ionic liquid.
  • the above-described mixed cellulose ester can be formed by a process where a first portion of the first pendant acyl groups can initially be donated from the acylating reagent to the carboxylated ionic liquid, and then the same acyl groups can be donated from the carboxylated ionic liquid to the cellulose (i.e., indirectly transferred from the acylating reagent to the cellulose, via the ionic liquid). Additionally, a second portion of the first pendant acyl groups can be donated directly from the acylating reagent to the cellulose.
  • the 2 or more acylating reagents can be added as a mixture or the addition can be staged.
  • a mixed addition 2 or more acylating reagents are added to the cellulose solution simultaneously.
  • carboxylated ionic liquids where one of the acyl groups are donated by the ionic liquid
  • addition of one or more acylating reagents constitutes a mixed addition.
  • the acylating reagents are added consecutively. In one embodiment of the staged addition process, at least about 80 mol percent of the first acylating reagent is allowed to react with the cellulose prior to adding the next acylating reagent.
  • the amount of acylating reagent that is added, and the order of which they are added can also significantly influence substituent distribution or regioselectivity when the total DS is less than about 2.95.
  • Regioselectivity is most easily measured by determining the relative degree of substitution (RDS) at C 6 , C 3 , and C 2 in the cellulose ester by carbon 13 NMR (Macromolecules, 1991 , 24, 3050-3059).
  • RDS relative degree of substitution
  • the RDS can be most easily determined directly by integration of the ring carbons.
  • 2 or more acyl substituents are present in more equal amounts, in addition to determining the ring RDS it is sometimes necessary to fully substitute the cellulose ester with an additional substituent in order to independently determine the RDS of each substituent by integration of the carbonyl carbons.
  • conventional cellulose esters regioselectivity is generally not observed, and the RDS ratio of C 6 /C 3 , C 6 /C 2 , or C 3 /C 2 is generally near 1.
  • conventional cellulose esters are random copolymers.
  • the present invention we found that when adding one or more acylating reagents, the C & position of cellulose was acylated much faster than C2 and C 3 . Consequentially, the C 6 /C 3 and C 6 /C 2 RDS ratios are greater than 1 which is characteristic of a regioselectively substituted cellulose ester.
  • the degree of regioselectivity depends upon at least one of the following factors: type of acyl substituent, contact temperature, ionic liquid interaction, equivalents of acyl reagent, order of additions, and the like.
  • the Ce position of the cellulose is acylated preferentially over the C 2 and C 3 position.
  • the C 6 position of the cellulose can be acylated preferentially overthe C2 or C 3 position.
  • the type of ionic liquid and its interaction with cellulose in the process can affect the regioselectivity of the cellulose ester. For example, when carboxylated ionic liquids are utilized, a regioselectively substituted cellulose ester is produced where the RDS ratio is C 6 >C2>C 3 .
  • a regioselectively substituted cellulose ester is produced where the RDS ratio is C 6 >C 3 >C 2 . This is significant in that regioselective placement of substituents in a cellulose ester leads to regioselectively substituted cellulose esters with different physical properties relative to conventional cellulose esters.
  • no protective groups are utilize to prevent reaction of the cellulose with the acylating reagent.
  • the ring RDS ratio for C 6 ZC 3 or C 6 /C 2 is at least 1.05. In another embodiment, the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 is at least 1.1. Another embodiment of the present invention is when the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 is at least 1.3.
  • the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS [(C 6 ZC 3 ) * DS or (C 6 ZC 2 ) 4 DS] is at least 2.9. In another embodiment, the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS is at least 3.0. In another embodiment, the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS is at least 3.2.
  • the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 is at least 1.05, and the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS is at least 2.9.
  • the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 is at least 1.1 , and the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS is at least 3.0.
  • the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 is at least 1.3, and the product of the ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the total DS is at least 3.2.
  • the carbonyl RDS ratio of at least one acyl substituent for C 6 ZC 3 or C 6 ZC 2 is at least 1.3. In another embodiment, the carbonyl RDS ratio of at least one acyl substituent for C 6 ZC 3 or C 6 ZC 2 is at least 1.5. In another embodiment, the carbonyl RDS ratio of at least one acyl substituent for C 6 ZC 3 or C 6 ZC 2 is at least 1.7.
  • the product of the carbonyl RDS ratio of at least one acyl substituent for C 6 ZC 3 or C 6 ZC 2 times the DS of the acyl substituent [(C 6 ZC 3 ) * DS aC yi or (C 6 ZC 2 ) 4 DSaCyI] is at least 2.3.
  • the product of the carbonyl RDS ratio for C 6 ZC 3 or C 6 ZC 2 times the DS of the acyl substituent is at least 2.5.
  • the product of the carbonyl RDS ratio for C 6 /C 3 or C 6 /C 2 times the DS of the acyl substituent is at least 2.7.
  • the carbonyl RDS ratio of at least one acyl substituent for C 6 ZC 3 or CeIC 2 is at least 1.3, and the product of the carbonyl RDS ratio for C 6 ICz or C 6 ZC 2 times the acyl DS is at least 2.3.
  • the carbonyl RDS ratio for CVC 3 or CQIC 2 is at least 1.5, and the product of the carbonyl RDS ratio for C 6 ICz or C 6 IC 2 times the acyl DS is at least 2.5.
  • the carbonyl RDS ratio for C 6 ICz or C 6 IC 2 is at least 1.7 and the product of the carbonyl RDS ratio for C 6 /C 3 or C 6 IC 2 times the acyl DS is at least 2.7.
  • staged additions of the acylating reagent gave a relative degree of substitution (RDS) different from that obtained in the mixed addition of acylating reagent
  • RDS relative degree of substitution
  • both the staged and mixed additions of the present invention provide a different RDS relative to other means known in the prior art for making mixed cellulose esters which generally provide cellulose esters with a RDS at C 6 , C 3 , and C 2 of about 1 :1 :1.
  • the prior art methods provide a RDS where the RDS at C 6 is less than that of C 2 and C 3 .
  • the temperature in esterification zone 40 during the above-described esterification process can be in the range of from about 0 to about 120 0 C, in the range of from about 20 to about 80°C, or in the range of from 25 to 50°C.
  • the cellulose can have a residence time in esterification zone 40 in the range of from about 1 minute to about 48 hours, in the range of from about 30 minutes to about 24 hours, or in the range of from 1 to 5 hours.
  • an esterified medium can be withdrawn from esterification zone 40 via line 80.
  • the esterified medium withdrawn from esterification zone 40 can comprise an initial cellulose ester.
  • the initial cellulose ester in line 80 can be a regioselectively substituted cellulose ester. Additionally, as mentioned above, the initial cellulose ester in line 80 can be a mixed cellulose ester.
  • the initial cellulose ester can have a degree of substitution ("DS") in the range of from about 0.1 to about 3.5; about 0.1 to about 3.08, about 0.1 to about 3.0, about 1.8 to about 2.9, or in the range of from 2.0 to 2.6.
  • the initial cellulose ester can have a DS of at least 2. Additionally, the initial cellulose ester can have a DS of less than 3.0, or less than 2.9.
  • the degree of polymerization ("DP") of the cellulose esters prepared by the methods of the present invention can be at least 10, at least 50, at least 100, or at least 250.
  • the DP of the initial cellulose ester can be in the range of from about 5 to about 1 ,000, or in the range of from 10 to 250.
  • the esterified medium in line 80 can comprise the initial cellulose ester in an amount in the range of from about 2 to about 80 weight pecent, in the range of from about 10 to about 60 weight percent, or in the range of from 20 to 40 weight percent based on weight of ionic liquid.
  • the esterified medium withdrawn from esterification zone 40 via line 80 can also comprise other components, such as, for example, altered ionic liquid, residual acylating reagent, and/or one or more carboxylic acids.
  • the esterified medium in line 80 can comprise a ratio of altered ionic liquid to initial ionic liquid introduced into dissolution zone 20 in an amount in the range of from about 0.01 to about 99.99 weight percent, in the range of from about 10 to about 99 weight percent, or in the range of from 90 to 98 weight percent based on the total amount of initial ionic liquid. Additionally, the esterified medium in line 80 can comprise residual acylating reagent in an amount less than about 20 weight percent, less than about 10 weight percent, or less than 5 weight percent.
  • the esterified medium in line 80 can comprise a total concentration of carboxylic acids in an amount in the range of from about 0.01 to about 40 weight percent, in the range of from about 0.05 to about 20 weight percent, or in the range of from 0.1 to 5 weight percent. In another embodiment, the esterified medium in line 80 can comprise a total concentration of carboxylic acids in an amount less than 40, less than 20, or less than 5 weight percent.
  • Carboxylic acids that can be present in the esterified medium in line 80 include, but are not limited to, formic acid, acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, hexanoic acid, 2-ethylhexanoic acid, nonanoic acid, lauric acid, palmitic acid, stearic acid, benzoic acid, substituted benzoic acids, phthalic acid, and/or isophthalic acid.
  • the esterified medium in line 80 can be routed to cellulose ester recovery/treatment zone 50.
  • at least a portion of the cellulose ester can optionally be subjected to at least one randomization process in recovery/treatment zone 50, thereby producing a randomized cellulose ester.
  • at least a portion of the cellulose ester can be caused to precipitate out of the esterified medium, at least a portion of which can thereafter be separated from the resulting mother liquor.
  • the cellulose ester precipitated and recovered in recovery/treatment zone 50 can be withdrawn via line 90 as a final cellulose ester.
  • the final cellulose ester exiting recovery/treatment zone 50 via line 90 can have a number average molecular weight ("Mn") in the range of from about 1 ,200 to about 200,000, in the range of from about 6,000 to about 100,000, or in the range of from 10,000 to 75,000.
  • Mw weight average molecular weight
  • Mw weight average molecular weight
  • the final cellulose ester exiting recovery/treatment zone 50 via line 90 can have a Z average molecular weight ("Mz") in the range of from about 4,000 to about 850,000, in the range of from about 12,000 to about 420,000, or in the range of from 40,000 to 330,000.
  • the final cellulose ester exiting recovery/treatment zone 50 via line 90 can have a polydispersity in the range of from about 1.3 to about 7, in the range of from about 1.5 to about 5, or in the range of from 1.8 to 3.
  • the final cellulose ester in line 90 can have a DP and DS as described above in relation to the initial cellulose ester in line 80.
  • the cellulose ester can be random or non- random, as is discussed in more detail below with reference to FIG. 2.
  • the final cellulose ester in line 90 can comprise a plurality of ester substituents as described above.
  • the final cellulose ester in line 90 can optionally be a mixed cellulose ester as described above.
  • the cellulose ester in line 90 can be in the form of a wet cake.
  • the wet cake in line 90 can comprise a total liquid content of less than 99, less than 50, or less than 25 weight percent.
  • the wet cake in line 90 can comprise a total ionic liquid concentration of less than 1 , less than 0.01 , or less than 0.0001 weight percent.
  • the wet cake in line 90 can comprise a total alcohol content of less than 100, less than 50, or less than 25 weight percent.
  • the final cellulose ester can be dried to produce a dry final cellulose ester product.
  • cellulose esters prepared by the methods of this invention can be used in a variety of applications. Those skilled in the art will understand that the specific application will depend upon various characteristics of the cellulose ester, such as, for example, the type of acyl substituent, DS, molecular weight, and type of cellulose ester copolymer.
  • the cellulose esters can be used in thermoplastic applications in which the cellulose ester is used to make film or molded objects.
  • cellulose esters suitable for use in thermoplastic applications include cellulose acetate, cellulose propionate, cellulose butyrate, cellulose acetate propionate, cellulose acetate butyrate, or mixtures thereof.
  • the cellulose esters can be used in coating applications.
  • coating applications include but, are not limited to, automotive, wood, plastic, or metal coating processes.
  • cellulose esters suitable for use in coating applications include cellulose acetate, cellulose propionate, cellulose butyrate, cellulose acetate propionate, cellulose acetate butyrate, or mixtures thereof.
  • the cellulose esters can be used in personal care applications. In personal care applications, cellulose esters can be dissolved or suspended in appropriate solvents. The cellulose ester can then act as a structuring agent, delivery agent, and/or film forming agent when applied to skin or hair.
  • cellulose esters suitable for use in personal care applications include cellulose acetate, cellulose propionate, cellulose butyrate, cellulose acetate propionate, cellulose acetate butyrate, cellulose hexanoate, cellulose 2-ethylhexanoate, cellulose laurate, cellulose palmitate, cellulose stearate, or mixtures thereof.
  • the cellulose esters can be used in drug delivery applications.
  • the cellulose ester can act as a film former such as in the coating of tablets or particles.
  • the cellulose ester can also be used to form amorphous mixtures of poorly soluble drugs, thereby improving the solubility and bioavailability of the drugs.
  • the cellulose esters can also be used in controlled drug delivery, where the drug can be released from the cellulose ester matrix in response to external stimuli such as a change in pH.
  • cellulose esters suitable for use in drug delivery applications include cellulose acetate, cellulose propionate, cellulose butyrate, cellulose acetate propionate, cellulose acetate butyrate, cellulose acetate phthalate, or mixtures thereof.
  • the cellulose esters of the present invention can be used in applications involving solvent casting of film.
  • applications include photographic film, protective film, and compensation film for liquid crystalline displays.
  • cellulose esters suitable for use in solvent cast film applications include, but are not limited to, cellulose triacetate, cellulose acetate, cellulose propionate, and cellulose acetate propionate.
  • films are produced comprising cellulose esters of the present invention and are used as protective and compensation films for liquid crystalline displays (LCD).
  • LCD liquid crystalline displays
  • the film When used as a protective film, the film is typically laminated to either side of an oriented, iodinated polyvinyl alcohol (PVOH) polarizing film to protect the PVOH layer from scratching and moisture, while also increasing structural rigidity.
  • PVOH polyvinyl alcohol
  • compensation films or plates
  • they can be laminated with the polarizer stack or otherwise included between the polarizer and liquid crystal layers.
  • These compensation films can improve the contrast ratio, wide viewing angle, and color shift performance of the LCD. The reason for this important function is that for a typical set of crossed polarizers used in an LCD, there is significant light leakage along the diagonals (leading to poor contrast ratio), particularly as the viewing angle is increased.
  • Compensation films are commonly quantified in terms of birefringence, which is, in turn, related to the refractive index n.
  • the refractive index is approximately 1.46 to 1.50.
  • the refractive index will be the same regardless of the polarization state of the entering light wave.
  • the refractive index becomes dependent on material direction.
  • there are three refractive indices of importance denoted n x , n y , and n z , which correspond to the machine direction (MD), the transverse direction (TD), and the thickness direction, respectively.
  • MD machine direction
  • TD transverse direction
  • thickness direction respectively.
  • birefringence of the material for that particular combination of refractive indices.
  • the birefringence ⁇ e is a measure of the relative in-plane orientation between the MD and TD and is dimensionless. In contrast, ⁇ th gives a measure of the orientation of the thickness direction, relative to the average planar orientation.
  • R optical retardation
  • ⁇ e d (n ⁇ -n y )d
  • Retardation is a direct measure of the relative phase shift between the two orthogonal optical waves and is typically reported in units of nanometers (nm). Note that the definition of R th varies with some authors, particularly with regards to the sign ( ⁇ ).
  • Compensation films or plates can take many forms depending upon the mode in which the LCD display device operates.
  • a C- plate compensation film is isotropic in the x-y plane, and the plate can be positive (+C) or negative (-C).
  • n x n y ⁇ n z .
  • n x n y >n z .
  • A-plate compensation film which is isotropic in the y-z direction, and again, the plate can be positive (+A) or negative (-A).
  • aliphatic cellulose esters provide values of Rm ranging from about 0 to about -350 nm at a film thickness of 60 ⁇ m.
  • the most important factors that influence the observed R th is type of substituent and the degree of substitution of hydroxyl (DSOH)- Film produced using cellulose mixed esters with very low DSOH in Shelby et al. (US 2009/0050842) had R t h values ranging from about 0 to about -50 nm.
  • Shelton et al. US 2009/0096962
  • Shelton et al. demonstrated that larger absolute values of R t h ranging from about -100 to about -350 nm could be obtained.
  • Cellulose acetates typically provide R th values ranging from about -40 to about -90 nm depending upon DSOH- [00133]
  • One aspect of the present invention relates to compensation film comprising regioselectively substituted cellulose esters wherein the compensation film has an R th range from about -400 to about +100 nm .
  • compensation films are provided comprising regioselectively substituted cellulose esters having a total DS from about 1.5 to about 2.95 of a single acyl substituent (DS ⁇ 0.2 of a second acyl substituent) and wherein the compensation film has an R th value from about -400 to about +100nm.
  • the regioselectively substituted cellulose esters utilized for producing films are selected from the group consisting of cellulose acetate, cellulose propionate, and cellulose butyrate wherein the regioselectively substituted cellulose ester has a total DS from about 1.6 to about 2.9.
  • the compensation film has R t h values from about -380 to about -110 nm and is comprised of a regioselectively substituted cellulose propionate having a total DS of about 1.7 to about 2.5.
  • the compensation film has R th values from about -380 to about -110 nm and is comprised of a regioselectively substituted cellulose propionate having a total DS of about 1.7 to about 2.5 and a ring RDS ratio for C 6 /C 3 or C 6 ZC 2 of at least 1.05.
  • the compensation film has R th values from about -60 to about +100 nm and is comprised of regioselectively substituted cellulose propionate having a total DS of about 2.6 to about 2.9.
  • the compensation film has R th values from about -60 to about +100 nm and is comprised of regioselectively substituted cellulose propionate having a total DS of about 2.6 to about 2.9 and a ring RDS ratio for C 6 ZC 3 or C 6 IC 2 of at least 1.05.
  • the compensation film has R th values from about 0 to about +100 nm and is comprised of a regioselectively substituted cellulose propionate having a total DS of about 2.75 to about 2.9.
  • the compensation film has R th values from about 0 to about +100 nm and is comprised of a regioselectively substituted cellulose propionate having a total DS of about 2.75 to about 2.9 and a ring RDS ratio for C 6 ZC 3 or C 6 ZC 2 of at least 1.05.
  • R th range from about -160 to about +270 nm comprised of regioselectively substituted cellulose esters having a total DS from about 1.5 to about 3.0 of a plurality of 2 or more acyl substituents.
  • the cellulose esters can be selected from the group consisting of cellulose acetate propionate, cellulose acetate butyrate, cellulose benzoate propionate, and cellulose benzoate butyrate; wherein the regioselectively substituted cellulose ester has a total DS from about 2.0 to about 3.0.
  • the compensation film has R th values from about -160 to about 0 nm and is comprised of a regioselectively substituted cellulose acetate propionate having a total DS of about 2.0 to about 3.0, a ring RDS ratio for C 6 /C 3 or C 6 IC 2 of at least 1.05, and a carbonyl RDS ratio for at least one acyl substituent for C 6 ZC 3 or C 6 IC 2 of at least about 1.3.
  • the compensation film has R th values from about +100 to about +270 nm and is comprised of a regioselectively substituted cellulose benzoate propionate having a total DS of about 2.0 to about 3.0, a ring RDS ratio for C 6 ICz or C 6 IC 2 of at least 1.05, and a carbonyl RDS ratio for at least one acyl substituent for C 6 ICz or C 6 IC 2 of at least about 1.3.
  • the compensation film has R th values from about +100 to about +270 nm and is comprised of a regioselectively substituted cellulose benzoate propionate having a total DS of about 2.0 to about 3.0, a ring RDS ratio for C 6 ICz or C 6 IC 2 of at least 1.05, a carbonyl RDS ratio for at least one acyl substituent for C 6 ICz or C 6 IC 2 of at least about 1.3, and the benzoate substituent is located primarily at C2 or C3.
  • At least a portion of the mother liquor produced in cellulose ester recovery/treatment zone 50 can be withdrawn via line 86 and routed to ionic liquid recovery/treatment zone 60.
  • the mother liquor can undergo various treatments in ionic liquid recovery/treatment zone 60.
  • Such treatment can include, but is not limited to, volatiles removal and reformation of the ionic liquid. Reformation of the ionic liquid can include, but is not limited to, (1) anion homogenization, and (2) anion exchange. Accordingly, a recycled ionic liquid can be formed in ionic liquid recovery/treatment zone 60.
  • At least a portion of the recycled ionic liquid can be withdrawn from ionic liquid recovery/treatment zone 60 via line 70.
  • the recycled ionic liquid in line 70 can have a composition such as described above in relation to the ionic liquid in line 64 of FIG. 1. The production and composition of the recycled ionic liquid will be discussed in greater detail below with reference to FIG. 2.
  • at least a portion of the recycled ionic liquid in line 70 can be routed back to dissolution zone 20.
  • at least about 80 weight percent, at least about 90 weight percent, or at least 95 weight percent of the recycled ionic liquid produced in ionic liquid recovery/treatment zone 60 can be routed to dissolution zone 20.
  • a cellulose can be introduced into an optional modification zone 110 via line 162.
  • the cellulose fed to optional modification zone 110 can be substantially the same as the cellulose in line 62 described above with reference to FIG. 1.
  • the cellulose can be modified employing at least one modifying agent.
  • water may be employed as the modifying agent.
  • a water-wet cellulose can be withdrawn from optional modification zone 110 and added to one or more ionic liquids in dissolution zone 120.
  • the cellulose can be mixed with water then pumped into one or more ionic liquids as a slurry.
  • excess water can be removed from the cellulose, and thereafter the cellulose can be added to the one or more ionic liquids in the form of a wet cake.
  • the cellulose wet cake can contain associated water in an amount in the range of from about 10 to about 95 weight percent, in the range of from about 20 to about 80 weight percent, or in the range of from 25 to 75 weight percent, based on the combined weight of the cellulose and associated water.
  • water wet cellulose has unexpectedly and unpredictably been found to provide at least three heretofore unknown benefits.
  • water can increase dispersion of the cellulose in the one or more ionic liquids so that when removal of water is initiated while heating the cellulose, the cellulose rapidly dissolves in the one or more ionic liquids.
  • water appears to reduce the melting points of ionic liquids that are normally solids at room temperature, thus allowing processing of ionic liquids at ambient temperatures.
  • a third benefit is that the molecular weight of cellulose esters prepared using initially water wet cellulose is reduced during the above-discussed esterification in esterification zone 40 when compared to cellulose esters prepared using initially dry cellulose.
  • This third benefit is particularly surprising and useful.
  • the molecular weight of cellulose is not reduced during dissolution or during esterification. That is, the molecular weight of the cellulose ester product is directly proportionate to the molecular weight of the initial cellulose.
  • Typical wood pulps used to prepare cellulose esters generally have a DP in the range of from about 1 ,000 to about 3,000. However, the desired DP range of cellulose esters can be from about 10 to about 500.
  • the cellulose in the absence of molecular weight reduction during esterification, the cellulose must be specially treated prior to dissolving the cellulose in the ionic liquid or after dissolving in the ionic liquid but prior to esterification.
  • the DP of the modified cellulose subjected to esterification can be within about 10 percent of, within about 5 percent of, within 2 percent of, or substantially the same as the DP of the initial cellulose subjected to modification.
  • the DP of the cellulose ester produced in accordance with embodiments of the present invention can be less than about 90 percent, less than about 70 percent, or less than 50 percent of the DP of the modified cellulose subjected to esterification.
  • the optionally modified cellulose in line 166 can be introduced into dissolution zone 120.
  • the optionally modified cellulose can be dispersed in one or more ionic liquids, as described above with reference to dissolution zone 20 in FIG. 1.
  • at least a portion of the modifying agent in the resulting cellulose/ionic liquid mixture can be removed.
  • at least 50 weight percent of all modifying agents can be removed, at least 75 weight percent of all modifying agents can be removed, at least 95 weight percent of all modifying agents can be removed, or at least 99 weight percent of all modifying agents can be removed from the cellulose/ionic liquid mixture.
  • Removal of one or more modifying agents in dissolution zone 120 can be accomplished by any means known in the art for liquid/liquid separation, such as, for example, distillation, flash vaporization, and the like. Removed modifying agent can be withdrawn from dissolution zone 120 via line 124.
  • dissolution zone 120 can produce a cellulose solution in substantially the same manner as dissolution zone 20, as described above with reference to FIG. 1. Thereafter, a cellulose solution can be withdrawn from dissolution zone 120 via line 176.
  • the cellulose solution in line 176 can comprise ionic liquid, cellulose, and a residual concentration of one or more optional modifying agents.
  • the cellulose solution in line 176 can comprise cellulose in an amount in the range of from about 1 to about 40 weight percent, in the range of from about 5 to about 30 weight percent, or in the range of from 10 to 20 weight percent, based on the weight of the ionic liquid.
  • the cellulose solution in line 176 can comprise a cumulative amount of residual modifying agents in an amount of less than about 50 weight percent, less than about 25 weight percent, less than about 15 weight percent, less than about 5 weight percent, or less than 1 weight percent.
  • esterification zone 140 can be operated in substantially the same manner as esterification zone 40, as described above with reference to FIG. 1.
  • an acylating reagent can be introduced into esterification zone 140 via line 178.
  • the acylating reagent can esterify at least a portion of the cellulose in esterification zone 140.
  • at least a portion of the resulting cellulose ester can comprise one or more ester substituents that originated from and or were donated by the ionic liquid.
  • an esterified medium can be withdrawn via line 180.
  • the esterified medium in line 180 can be substantially the same as the esterified medium in line 80, as described above with reference to FIG. 1.
  • the esterified medium in line 180 can comprise an initial cellulose ester and other components, such as, for example, altered ionic liquid, residual acylating reagent, one or more carboxylic acids, and/or one or more catalysts.
  • the concentrations of the initial cellulose ester and other components in the esterified medium in line 180 can be substantially the same as the esterified medium in line 80 described above with reference to FIG. 1.
  • the initial cellulose ester produced in esterification zone 140 can be a non-random cellulose ester.
  • at least a portion of the initial cellulose in line 180 can optionally be introduced into randomization zone 151 to undergo randomization, thereby creating a random cellulose ester.
  • Randomization of the initial cellulose can comprise introducing at least one randomizing agent into randomization zone 151 via line 181. Additionally, as will be discussed in further detail below, at least a portion of the randomization agent introduced into randomization zone 151 can be introduced via line 194.
  • the randomization agent employed in the present invention can be any substance capable lowering the DS of the cellulose ester via hydrolysis or alcoholysis, and/or by causing migration of at least a portion of the acyl groups on the cellulose ester from one hydroxyl to a different hydroxyl, thereby altering the initial monomer distribution.
  • suitable randomizing agents include, but are not limited to water and/or alcohols.
  • Alcohols suitable for use as the randomizing agent include, but are not limited to methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, t- butanol, phenol and the like.
  • methanol can be employed as the randomizing agent introduced via line 181.
  • the amount of randomizing agent introduced into randomization zone 151 can be in the range of from about 0.5 to about 20 weight percent, or in the range of from 3 to 10 weight percent, based on the total weight of the resulting randomization medium in randomization zone 151.
  • the randomization medium can have any residence time in randomization zone 151 suitable to achieve the desired level of randomization.
  • the randomization medium can have a residence time in randomization zone 151 in the range of from about 1 min. to about 48 hours, in the range of from about 30 min. to about 24 hours, or in the range of from 2 to 12 hours.
  • the temperature in randomization zone 151 during randomization can be any temperature suitable to achieve the desired level of randomization.
  • the temperature in randomization zone 151 during randomization can be in the range of from about 20 to about 120°C, in the range of from about 30 to about 100 0 C, or in the range of from 50 to 80 0 C.
  • the DS and DP of the cellulose ester random copolymer might be less than that of the cellulose ester non-random copolymer. Accordingly, in this embodiment the non- random cellulose ester entering randomization zone 151 may optionally have a greater DS and/or DP than the target DS and/or DP of the randomized cellulose ester.
  • Non-random cellulose esters prepared by the methods of the present invention can be at least partially soluble in acetone when they have a DS in the range of from about 2.1 to about 2.4, in the range of from about 2.28 to about 2.39 or in the range of from 2.32 to 2.37.
  • an optionally randomized medium can be withdrawn from randomization zone 151 via line 182.
  • the optionally randomized medium can comprise randomized cellulose ester and residual randomizing agent.
  • the optionally randomized medium in line 182 can comprise randomized cellulose ester in an amount in the range of from about 2 to about 80 weight percent, in the range of from about 10 to about 60 weight percent, or in the range of from 20 to 40 weight percent based on the weight of the ionic liquid.
  • the optionally randomized medium can comprise residual randomizing agent in the range of from about 0.5 to about 20 weight percent, or in the range of from 3 to 10 weight percent, based on the total weight of the resulting randomized medium.
  • the optionally randomized medium in line 182 can comprise other components, such as those described above with reference to the esterified medium in line 180 and with reference to the esterified medium in line 80 of FIG. 1.
  • Such components include, but are not limited to, altered ionic liquid, residual acylating reagent, one or more carboxylic acids, and/or one or more catalysts.
  • Precipitation zone 152 can operate to cause at least a portion of the cellulose ester from the esterified and optionally randomized medium to precipitate. Any methods known in the art suitable for precipitating a cellulose ester can be employed in precipitation zone 152.
  • a precipitating agent can be introduced into precipitation zone 152, thereby causing at least a portion of the cellulose ester to precipitate.
  • the precipitating agent can be a non-solvent for the cellulose ester.
  • the precipitating agent introduced into precipitation zone 152 can comprise methanol.
  • the amount of precipitating agent introduced into precipitation zone 152 can be any amount sufficient to cause at least a portion of the cellulose ester to precipitate. In one embodiment, the amount of precipitating agent introduced into precipitation zone 152 can be at least about 20 volumes, at least 10 volumes, or at least 4 volumes, based on the total volume of the medium entering precipitation zone 152.
  • the resulting precipitation medium can have any residence time in precipitation zone 152 suitable to achieve the desired level of precipitation.
  • the precipitation medium can have a residence time in precipitation zone 152 in the range of from about 1 to about 300 min., in the range of from about 10 to about 200 min., or in the range of from 20 to 100 min.
  • the temperature in precipitation zone 152 during precipitation can be any temperature suitable to achieve the desired level of precipitation.
  • the temperature in precipitation zone 152 during precipitation can be in the range of from about 0 to about 120 0 C, in the range of from about 20 to about 100 0 C, or in the range of from 25 to 50°C.
  • the amount of cellulose ester precipitated in precipitation zone 152 can be at least 50 weight percent, at least 75 weight percent, or at least 95 weight percent, based on the total amount of cellulose ester in precipitation zone 152.
  • a cellulose ester slurry can be withdrawn via line 184 comprising a final cellulose ester.
  • the cellulose ester slurry in line 184 can have a solids content of less than about 50 weight percent, less than about 25 weight percent, or less than 1 weight percent.
  • At least a portion of the cellulose ester slurry in line 184 can be introduced into separation zone 153.
  • separation zone 153 at least a portion of the liquid content of the cellulose ester slurry can be separated from the solids portion.
  • Any solid/liquid separation technique known in the art for separating at least a portion of a liquid from a slurry can be used in separation zone 153.
  • suitable solid/liquid separation techniques suitable for use in the present invention include, but are not limited to, centrifugation, filtration, and the like.
  • at least 50 weight percent, at least 70 weight percent, or at least 90 weight percent of the liquid portion of the cellulose ester slurry can be removed in separation zone 153.
  • separation zone 153 can have any temperature or pressure suitable for solid liquid separation.
  • the temperature in separation zone 153 during separation can be in the range of from about 0 to about 120 0 C, in the range of from about 20 to about 100 0 C, or in the range of from 25 to 50°C.
  • a cellulose ester wet cake can be withdrawn from separation zone 153 via line 187.
  • the cellulose ester wet cake in line 187 can have a total solids content of at least 1 weight percent, at least 50 weight percent, or at least 75 weight percent. Additionally, the cellulose ester wet cake in line 187 can comprise cellulose ester in an amount of at least 70 weight percent, at least 80 weight percent, or at least 90 weight percent. Additionally, as will be discussed in greater detail below, at least a portion of the separated liquids from separation zone 153 can be withdrawn via line 186.
  • wash zone 154 At least a portion of the cellulose ester solids from the cellulose ester wet cake can be washed in wash zone 154. Any method known in the art suitable for washing a wet cake can be employed in wash zone 154.
  • An example of a washing technique suitable for use in the present invention includes, but is not limited to, a multistage counter-current wash.
  • a wash liquid that is a non- solvent for cellulose ester can be introduced into wash zone 154 via line 188 to wash at least a portion of the cellulose ester solids.
  • wash liquids include, but are not limited to, a Ci to C 8 alcohol, water, or a mixture thereof.
  • the wash liquid can comprise methanol. Additionally, as will be described in greater detail below, at least a portion of the wash liquid can be introduced into wash zone 154 via line 194.
  • washing of the cellulose ester solids in wash zone 153 can be performed in such a manner that at least a portion of any undesired by-products and/or color bodies are removed from the cellulose ester solids and/or ionic liquid.
  • the non-solvent wash liquid can contain a bleaching agent in the range of from about 0.001 to about 50 weight percent, or in the range of from 0.01 to 5 weight percent based on the total weight of the wash fluid.
  • chlorites such as sodium chlorite (NaCIO 2 ); hypohalites, such as NaOCI, NaOBr and the like
  • peroxides such as hydrogen peroxide and the like
  • peracids
  • the bleaching agent employed in the present invention can include hydrogen peroxide, NaOCI, sodium chlorite and/or sodium sulfite. Washing in wash zone 153 can be sufficient to remove at least 50, at least 70, or at least 90 percent of the total amount of byproducts and/or color bodies.
  • a washed cellulose ester product can be withdrawn via line 189.
  • the washed cellulose ester product in line 189 can be in the form of a wet cake, and can comprise solids in an amount of at least 1 , at least 50, or at least 75 weight percent. Additionally, the washed cellulose ester product in line 189 can comprise cellulose ester in an amount of at least 1 , at least 50, or at least 75 weight percent.
  • the washed cellulose ester product can optionally be dried in drying zone 155.
  • Drying zone 155 can employ any drying methods known in the art to remove at least a portion of the liquid content of the washed cellulose ester product. Examples of drying equipment suitable for use in drying zone 155 include, but are not limited to, rotary dryers, screw-type dryers, paddle dryers, and/or jacketed dryers. In one embodiment, drying in drying zone 155 can be sufficient to produce a dried cellulose ester product comprising less than 5, less than 3, or less than 1 weight percent liquids.
  • a final cellulose ester product can be withdrawn via line 190.
  • the final cellulose ester product in line 190 can be substantially the same as the final cellulose ester product in line 90, as described above with reference to FIG. 1.
  • the separated liquids generated in separation zone 153 can be withdrawn via line 186 as a recycle stream.
  • the recycle stream in line 186 can comprise altered ionic liquid, one or more carboxylic acids, residual modifying agent, residual catalyst, residual acylating reagent, residual randomizing agent, and/or residual precipitation agent.
  • altered ionic liquid refers to an ionic liquid that has previously passed through a cellulose esterification step wherein at least a portion of the ionic liquid acted as acyl group donor and/or recipient.
  • modified ionic liquid refers to an ionic liquid that has previously been contacted with another compound in an upstream process step. Therefore, altered ionic liquids are a subset of modified ionic liquids, where the upstream process step is cellulose esterification.
  • the recycle stream in line 186 can comprise altered ionic liquid, one or more carboxylic acids, one or more alcohols, and/or water.
  • the recycle stream in line 186 can comprise altered ionic liquid in an amount in the range of from about 10 to about 99.99 weight percent, in the range of from about 50 to about 99 weight percent, or in the range of from 90 to 98 weight percent, based on the total weight of the recycle stream in line 186.
  • the altered ionic liquid can comprise an ionic liquid having at least two different anions: primary anions and secondary anions. At least a portion of the primary anions in the altered ionic liquid originate from the initial ionic liquid introduced into dissolution zone 120 via line 164, as described above.
  • the altered ionic liquid can comprise primary anions and secondary anions in a ratio in the range of from about 100:1 to about 1 :100, in the range of from about 1 :10 to about 10:1 , or in the range of from 1 :2 to about 2:1.
  • the altered ionic liquid can comprise a plurality of cations, such as those described above with reference to the initial ionic liquid in line 68 of FIG. 1.
  • the recycle stream in line 186 can comprise a total amount of carboxylic acids in an amount in the range of from about 5 to about 60 weight percent, in the range of from about 10 to about 40 weight percent, or in the range of from 15 to 30 weight percent based on the total weight of ionic liquid in the recycle stream in line 186.
  • suitable carboxylic acids the recycle stream in line 186 can comprise include, but are not limited to, acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, hexanoic acid, 2-ethylhexanoic acid, nonanoic acid, lauric acid, palmitic acid, stearic acid, benzoic acid, substituted benzoic acids, phthalic acid, and isophthalic acid.
  • at least 50 weight percent, at least 70 weight percent, or at least 90 weight percent of the carboxylic acids in the recycle stream in line 186 are acetic, propionic, and/or butyric acids.
  • the recycle stream in line 186 can comprise a total concentration of alcohols in an amount of at least 20 volumes, at least 10 volumes, or at least 4 volumes, based on the total volume of the recycle stream.
  • suitable alcohols the recycle stream in line 186 can comprise include, but are not limited to, Ci to Cs straight- or branched-chain alcohols.
  • at least 50 weight percent, at least 70 weight percent, or at least 90 weight percent of the alcohol in the separated ionic liquids in line 186 comprises methanol.
  • the recycle stream in line 186 can comprise water in an amount of at least 20 volumes, at least 10 volumes, or at least 4 volumes, based on the total volume of the recycle stream.
  • At least a portion of the recycle stream in line 186 can be introduced into ionic liquid recovery/treatment zone 160.
  • Ionic liquid recovery/treatment zone 160 can operate to segregate and/or reform at least a portion of the recycle stream from line 186.
  • at least a portion of the recycle stream can undergo at least one flash vaporization and/or distillation process to remove at least a portion of the volatile components in the recycle stream.
  • At least 40 weight percent, at least 75 weight percent, or at least 95 weight percent of the volatile components in the recycle stream can be removed via flash vaporization.
  • the volatile components removed from the recycle stream can comprise one or more alcohols.
  • the volatile components can comprise methanol.
  • the resulting volatiles-depleted recycle stream can comprise a total amount of alcohols in the range of from about 0.1 to about 60 weight percent, in the range of from about 5 to about 55 weight percent, or in the range of from 15 to 50 weight percent.
  • At least a portion of the carboxylic acids can be removed from the recycle stream. This can be accomplished by first converting at least a portion of the carboxylic acids to carboxylate esters.
  • at least a portion of the recycle stream can be placed into a pressurized reactor where the recycle stream can be treated at a temperature, pressure, and time sufficient to convert the at least a portion of the carboxylic acid to methyl esters, by reacting the carboxylic acids with the alcohol present in the recycle stream.
  • the pressurized reactor can have a temperature in the range of from 100 to 180 0 C, or in the range of from 130 to 160 0 C.
  • the pressure in the pressurized reactor during esterification can be in the range of from about 10 to about 1 ,000 pounds per square inch gauge ("psig"), or in the range of from 100 to 300 psig.
  • the recycle stream can have a residence time in the pressurized reactor in the range of from about 10 to about 1 ,000 minutes, or in the range of from 120 to 600 minutes.
  • the alcohol and carboxylic acid can be present in the recycle stream in a molar ratio in the range of from about 1 :1 to about 30:1 , in the range of from about 3:1 to about 20:1 , or in the range of from 5:1 to 10:1 alcohol-to-carboxylic acid.
  • at least 5, at least 20, or at least 50 mole percent of the carboxylic acids can be esterified during the above-described esterification.
  • the carboxylic acids can be acetic, propionic, and/or butyric acids.
  • the alcohol present in the recycle stream can be methanol.
  • the above-described esterification process can operate to produce methyl acetate, methyl propionate, and/or methyl butyrate.
  • at least 10, at least 50, or at least 95 weight percent of the resulting carboxylate esters can be removed from the recycle stream by any methods known in the art.
  • at least a portion of the carboxylate esters produced by the above described esterification can be routed to esterification zone 140 via line 196.
  • Carboxylate esters introduced into esterification zone 140 can be employed as immiscible cosolvents, as described above.
  • at least a portion of the carboxylate esters can be converted to anhydrides by CO insertion.
  • At least a portion of the altered ionic liquid present in the recycle stream can undergo reformation. Reformation of the altered ionic liquid can optionally be performed simultaneously with the esterification of the carboxylic acids in the recycle stream. Alternatively, reformation of the altered ionic liquid can be performed subsequently to the esterification of the carboxylic acids in the recycle stream. Reformation of the altered ionic liquid can comprise at least one anion exchange process.
  • reformation of the altered ionic liquid can comprise anion homogenization via anion exchange, such that substantially all of the anions of the altered ionic liquid are converted to the same type of anion.
  • at least a portion of the altered ionic liquid can be contacted with at least one alkyl formate.
  • Alkyl formates suitable for use in the present invention include, but are not limited to, methyl formate, ethyl formate, propyl formate, isopropyl formate, butyl formate, isobutyl formate, tert-butyl formate, hexyl formate, octyl formate, and the like.
  • the alkyl formate can comprise methyl formate.
  • reformation of the altered ionic liquid can be performed in the presence of one or more alcohols.
  • Alcohols suitable for use in this embodiment of the invention include, but are not limited to, alkyl or aryl alcohols such as methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, t-butanol, phenol and the like.
  • the alcohol present during reformation can comprise methanol.
  • the temperature during reformation of the altered ionic liquid can be in the range of from about 100 to about 200 0 C, or in the range of from 130 to about 170 0 C. Additionally, the pressure during reformation of the altered ionic liquid can be at least 700 kPa, or at least 1 ,025 kPa. Furthermore, the reaction time of the reformation of the altered ionic liquid can be in the range of from about 10 min. to about 24 hours, or in the range of from 3 to 18 hours.
  • reformation of the altered ionic liquid can comprise anion homogenization.
  • the resulting reformed ionic liquid can have an at least 90, at least 95, or at least 99 percent uniform anion content.
  • the reformed ionic liquid can comprise an alkyl amine formate.
  • the amine of the alkyl amine formate can be an imidazolium.
  • alkyl amine formates suitable for use as the reformed ionic liquid include, but are not limited to, 1-methyl-3- methylimidazolium formate, 1-ethyl-3-methylimidazolium formate, 1-propyl-3- methylimidazolium formate, 1-butyl-3-methylimidazolium formate, 1-hexyl-3- methylimidazolium formate, and/or 1-octyl-3-methylimidazolium formate.
  • At least a portion of the volatile components of the reformed ionic liquid can optionally be removed via any methods known in the art for removing volatile components.
  • Volatile components removed from the reformed ionic liquid can include, for example, carboxylate esters, such as those formed via the above described carboxylic acid esterification process.
  • at least a portion of the reformed ionic liquid can undergo at least one anion exchange process to replace at least a portion of the anions of the reformed ionic liquid thereby forming a carboxylated ionic liquid.
  • the reformed ionic liquid can be contacted with at least one carboxylate anion donor to at least partially effect the anion exchange.
  • Carboxylate anion donors suitable for use in this embodiment include, but are not limited to, one or more carboxylic acids, anhydrides, or alkyl carboxylates. Additionally, the carboxylate anion donors can comprise one or more C 2 to C 2 o straight- or branched-chain alkyl or aryl carboxylic acids, anhydrides, or methyl esters. Furthermore, the carboxylate anion donor can be one or more C 2 to Ci 2 straight-chain alkyl carboxylic acids, anhydrides, or methyl esters. Moreover, the carboxylate anion donor can be one or more C 2 to C 4 straight-chain alkyl carboxylic acids, anhydrides, or methyl esters.
  • the resulting carboxylated ionic liquid can be substantially the same as the carboxylated ionic liquid described above with reference to the carboxylated ionic liquid in line 64 of FIG. 1.
  • the contacting can be carried out in a contact mixture further comprising alcohol or water.
  • the alcohol or water can be present in the contact mixture in the range of from 0.01 to 20 molar equivalents per alkyl amine formate, or in the range of from 1 to 10 molar equivalents per alkyl amine formate.
  • methanol can be present in the contact mixture in the range of from 1 to 10 molar equivalents per alkyl amine formate.
  • At least a portion of the carboxylated ionic liquid produced in ionic liquid recovery/treatment zone 160 can be in a treated ionic liquid mixture further comprising at least one alcohol, at least one residual carboxylic acid, and/or water.
  • the one or more alcohols and/or residual carboxylic acids can be substantially the same as described above with reference to the recycle stream in line 186.
  • the treated ionic liquid mixture can be subjected to at least one liquid/liquid separation process to remove at least a portion of the one or more alcohols.
  • Such separation process can comprise any liquid/liquid separation process known in the art, such as, for example, flash vaporization and/or distillation.
  • the treated ionic liquid mixture can be subjected to at least one liquid/liquid separation process to remove at least a portion of the water.
  • Such separation process can comprise any liquid/liquid separation process known in the art, such as, for example, flash vaporization and/or distillation.
  • At least 50, at least 70, or at least 85 weight percent of the alcohols and/or water can be removed from the treated ionic liquid mixture thereby producing a recycled carboxylated ionic liquid.
  • At least a portion of the alcohol separated from the treated ionic liquid mixture can optionally be removed from ionic liquid recovery/treatment zone 160 via line 194.
  • the one or more alcohols in line 194 can thereafter optionally be routed to various other points depicted in FIG. 2.
  • at least 50, at least 70, or at least 90 weight percent of the alcohols removed from the treated ionic liquid mixture can be routed to various other points in the process depicted in FIG. 2.
  • At least a portion of the alcohols in line 194 can be routed to randomization zone 151 to be employed as a randomizing agent. In another optional embodiment, at least a portion of the alcohols in line 194 can be routed to precipitation zone 152 to be employed as a precipitating agent. In yet another optional embodiment, at least a portion of the alcohols in line 194 can be routed to wash zone 154 to be employed as a wash liquid.
  • At least a portion of the water separated from the treated ionic liquid mixture can optionally be removed from ionic liquid recovery/treatment zone 160 via line 192.
  • at least a portion of the water removed from ionic liquid recovery/treatment zone 160 can be routed to modification zone 110 to be employed as a modifying agent.
  • At least about 5, at least about 20, or at least 50 weight percent of the water separated from the treated ionic liquid mixture can optionally be routed to modification zone 110.
  • at least a portion of the water in line 192 can optionally be routed to a waste water treatment process.
  • the above-mentioned recycled carboxylated ionic liquid can comprise residual carboxylic acid in an amount in the range of from about 0.01 to about 25 weight percent, in the range of from about 0.05 to about 15 weight percent, or in the range of from 0.1 to 5 weight percent based on the entire weight of the recycled carboxylated ionic liquid. Additionally, the recycled carboxylated ionic liquid can comprise sulfur in an amount of less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw.
  • the recycled carboxylated ionic liquid can comprise halides in an amount less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw.
  • the carboxylated ionic liquid can comprise transition metals in an amount less than 200 ppmw, less than 100 ppmw, less than 50 ppmw, or less than 10 ppmw.
  • At least a portion of the recycled carboxylated ionic liquid produced in ionic liquid recovery/treatment zone 160 can optionally be routed to dissolution zone 120. At least 50 weight percent, at least 70 weight percent, or at least 90 weight percent of the recycled carboxylated ionic liquid produced in ionic liquid recovery/treatment zone 160 can be routed to dissolution zone 120.
  • the recycled carboxylated ionic liquid can be employed either individually or combined with the carboxylated ionic liquid entering dissolution zone 120 via line 164 to thereby form the above- described cellulose dissolving ionic liquid.
  • the recycled carboxylated ionic liquid can make up in the range of from about 10 to about 99.99 weight percent, in the range of from about 50 to about 99 weight percent, or in the range of from about 90 to about 98 weight percent of the cellulose dissolving ionic liquid in dissolution zone 120.
  • ionic liquids employed in the following examples were manufactured by BASF and were obtained through Fluka. These ionic liquids were used both as received and after purification as described in the examples. Experimental alkyl imidazolium carboxylates were also prepared as described in the examples.
  • Cellulose was obtained from Aldrich. The degree of polymerization of the Aldrich cellulose (DP ca. 335) was determined capillary viscometry using copper ethylenediamine (Cuen) as the solvent. Prior to dissolution in ionic liquids, the cellulose was typically dried for 14-18 h at 50 0 C and 5 mm Hg, except in cases where the cellulose was modified with water prior to dissolution.
  • the relative degree of substitution (RDS) at C 6 , C 3 , and C 2 in the cellulose ester of the present invention was determined by carbon 13 NMR following the general methods described in "Cellulose Derivatives", ACS Symposium Series 688, 1998, T.J. Heinze and W.G. Glasser, Editors, herein incorporated by reference to the extent it does not contradict the statements herein. Briefly, the carbon 13 NMR data was obtained using a JEOL NMR spectrometer operating at 100 MHz or a Bruker NMR spectrometer operating at 125 MHz. The sample concentration was 100 mg/mL of DMSO-d 6 . Five mg of Cr(OAcAc) 3 per 100 mg of sample were added as a relaxation agent.
  • the spectra were collected at 80 0 C using a pulse delay of 1 second. Normally, 15,000 scans were collected in each experiment. Conversion of a hydroxyl to an ester results in a downfield shift of the carbon bearing the hydroxyl and an upfield shift of a carbon gamma to the carbonyl functionality.
  • the RDS of the C 2 and C & ring carbons were determined by direct integration of the substituted and unsubstituted Ci and Ce carbons.
  • the RDS at C 3 was determined by subtraction of the sum of the C 6 and C 2 RDS from the total DS.
  • the carbonyl RDS was determined by integration of the carbonyl carbons using the general assignments described in Macromolecules, 1991 , 24, 3050- 3059, herein incorporated by reference to the extent it does not contradict the statements herein.
  • the cellulose ester was first converted to fully substituted cellulose mixed p-nitrobenzoate ester.
  • the position of the p-nitrobenzoate esters indicate the location of the hydroxy Is in the cellulose mixed ester.
  • Viscosity measurements were made using an AR2000 rheometer (TA Instruments LTD) interfaced with a computer running TA Instruments Advantage Software.
  • the 25 mm aluminum stage for the rheometer was enclosed in a plastic cover with a nitrogen purge to ensure that the samples did not pick up moisture during the measurements.
  • the ionic liquid-cellulose solutions were prepared by the general methods disclosed in the examples.
  • Solvent casting of film was performed according to the following general procedure: Cellulose ester solids and 10 wt% plasticizer were added to a 90/10 wt% solvent mixture of CH 2 CI 2 /methanol (or ethanol) to give a final concentration of 5-30 wt% based on cellulose ester + plasticizer. The mixture was sealed, placed on a roller, and mixed for 24 hours to create a uniform solution. After mixing, the solution was cast onto a glass plate using a doctor blade to obtain a film with the desired thickness. Casting was conducted in a fume hood with relative humidity controlled at 50%. After casting, the film and glass were allowed to dry for one hour under a cover pan (to minimize rate of solvent evaporation).
  • the film was peeled from the glass and annealed in a forced air oven for 10 minutes at 100 0 C. After annealing at 100 0 C, the film was annealed at a higher temperature (120 0 C) for another 10 minutes.
  • the slurry was stirred for 5 min before applying vacuum. After ca. 3 h 25 min, most of the cellulose had dissolved except for a few small pieces and 1 large piece stuck to the probe. After 5.5 h, the oil bath temperature was increased to 105 0 C to speed up dissolution of the remaining cellulose. The solution was maintained at 105 0 C for 1.5 h (47 min heat up) before allowing the solution to cool to room temperature (6 h 25 min from the start of the cellulose addition) and stand overnight at ambient temperature.
  • the 1 st sample was white, the 2 nd sample was tan, and the 3 rd sample was brown. During the course of the reaction, the solution became progressively darker. Approximately 2 h 45 min after the start of the Ac 2 O addition, the viscosity of the reaction mixture abruptly increased then the reaction mixture completely gelled. The oil bath was lowered and the contact solution was allowed to cool to room temperature.
  • Figure 3 is a plot of absorbance versus time for Example 1 and it shows the dissolution of cellulose (1046 cm '1 ) and the removal of residual water (1635 cm “1 ) from the mixture during the course of the dissolution.
  • the spikes in the cellulose trend line are due to large cellulose gel particles sticking to the probe which, are removed by the stirring action. Clumping occurs because the surfaces of the cellulose particles become partially dissolve before dispersion is obtained leading to clumping and large gel particles.
  • the dip in the trend lines near 6 h result from the temperature increase from 80 to 105 0 C. This figure illustrates that ca. 6 h is required to fully dissolve the cellulose when the cellulose is added to the ionic liquid that is preheated to 80 0 C.
  • Figure 4 is a plot of absorbance versus time for Example 1 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm “1 ), the consumption of AC 2 O (1822 cm '1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • DP ca. 335 microcrystalline cellulose
  • FIG. 5 is a plot of absorbance versus time for Example 2 and it shows the dissolution of cellulose (1046 cm '1 ) and the removal of residual water (1635 cm "1 ) from the mixture during the course of the dissolution. As can be seen, the dissolution of the cellulose was very rapid (17 min versus 360 min in Example 1).
  • [BMIm]CI is a solid that melts at ca. 70 0 C.
  • water or a carboxylic acid is allowed to mix with [BMIm]CI, the [BMIm]CI will remain a liquid at room temperature thus allowing introduction of the cellulose at ambient temperature.
  • the [BMIm]CI contained significant water. This example illustrates that the addition of water to an ionic liquid followed by cellulose addition and good mixing to get a good dispersion provides rapid dissolution of cellulose.
  • Figure 6 is a plot of absorbance versus time for Example 2 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm “1 ), the consumption of Ac 2 O (1822 cm “1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • Example 1 As was observed in Example 1 , the solution viscosity suddenly increased followed by gellation of the contact mixture, but in Example 2, gellation occurred at a lower DS. Both the slower reaction rate and gellation at a lower temperature can be attributed to the use of less Ac 2 O. However, it should be noted that there was still a large excess of Ac 2 O at the point of gellation. As with Example 1 , during the course of the contact period, the solution became progressively darker and the final product color was dark brown. Color measurements of the final sample dissolved in NMP gave a L * value of 67.30, an a * value of 17.53, a b * value of 73.35, and an E* value of 82.22.
  • the molecular weight of each sample was determined by GPC (Table 1 , below). In general, Mw was approximately 55,000 and the polydispersity ranged from 3-6. Based on the DP of the starting cellulose, this analysis indicates that the molecular weight of the cellulose polymer remained essentially intact during the contact period.
  • Figure 7 is a plot of absorbance versus time for Example 3 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm '1 ), the consumption Of Ac 2 O (1822 cm “1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • the DS values shown in Figure 7 were determined by NMR spectroscopy and correspond to the samples removed during the course of the contact period. What is apparent from Figure 7 is that the rates of reaction are much faster compared to Examples 2 and 3. For example, 55 min was required to reach a DS of 1.82 in Example 1-1 (Table 1 , below) while only 10 min was required to reach a DS of 1.81 in Example 3-1. Similarly, 166 min was required to reach a DS of 2.01 in Example 2-4 (Table 1 , below) while only 20 min was required to reach a DS of 2.18 in Example 3-
  • a secondary component such as MSA
  • Example 3 shows that inclusion of a secondary component such as MSA in the contact mixture accelerates the rates of reaction, significantly improves solution and product color, prevents gellation of the contact mixture, allows the achievement of high DS values while using less acylating reagent, and helps to promote lowering of the cellulose ester molecular weight.
  • a secondary component such as MSA
  • Figure 8 is a plot of absorbance versus time for Example 4 and it shows the dissolution of cellulose (1046 cm “1 ) and the removal of residual water (1635 cm “1 ) from the mixture during the course of the dissolution.
  • the dissolution of the water wet (activated) cellulose was very rapid (28 min) despite the presence of a significant amount of water. This is surprising in view of the conventional teachings.
  • the addition of water wet cellulose to the ionic liquid enables one to obtain a good dispersion of cellulose with little clumping. Upon application of a vacuum to remove the water, the cellulose rapidly dissolves without clumping to form large particles.
  • Figure 9 is a plot of absorbance versus time for Example 4 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm “1 ), the consumption of Ac 2 O (1822 cm “1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • the DS values shown in Figure 9 were determined by NMR spectroscopy and correspond to the samples removed during the course of the contact period. Relative to Example 3, the reaction rate to produce cellulose acetate was similar. However, the molecular weights (ca. 33,000) of the cellulose acetate samples (Table 2, below) were notably lower that that observed in Example 3 and much lower than that observed in Examples 1 and 2 (Table 1 , above).
  • the polydispersities for the samples of Example 4 are all less than 2, less than that observed for the samples of Examples 1 , 2, and 3.
  • This example illustrates that water wet cellulose leads to good cellulose dispersion in the ionic liquid and rapid cellulose dissolution. The reaction rate for formation of cellulose acetate is rapid. Surprisingly, water wet cellulose leads to lower molecular weight cellulose acetate with low polydispersities relative to dry cellulose. The cellulose acetate made from water wet cellulose has better acetone solubility relative to when dry cellulose is utilized.
  • To the flask added 67.33 g of 1-butyl-3-methylimidazolium chloride.
  • the IL Prior to adding the [BMIm]CI, the IL was melted at 90 0 C then stored in a desiccator.
  • the flask was placed in an oil bath and heated to 80 0 C.
  • Figure 10 is a plot of absorbance versus time for Example 5 and it shows the dissolution of cellulose (1046 cm “1 ) and the removal of residual water (1635 cm '1 ) from the mixture during the course of the dissolution. As can be seen, the dissolution of the water wet (activated) cellulose was very rapid (50 min) despite the presence of a significant amount of water and the increase in cellulose concentration relative to Example 4.
  • Figure 11 is a plot of absorbance versus time for Example 5 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm “1 ), the consumption Of Ac 2 O (1822 cm “1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • the DS values shown in Figure 11 were determined by NMR spectroscopy and correspond to the samples removed during the course of the contact period. Despite the increase in cellulose concentration, relative to Examples 3 and 4, the reaction rate to produce cellulose acetate was similar.
  • the molecular weights (ca.
  • To the flask added 51.82 g of 1-butyl-3-methylimidazolium chloride.
  • the IL Prior to adding the [BMIm]CI, the IL was melted at 90 0 C then stored in a desiccator.
  • the flask was placed in an oil bath and heated to 80 0 C.
  • the cellulose was allowed to stand in the water for 50 min before filtering which gave 18.9 g of a wet cellulose cake.
  • the water wet cellulose was then added in small portions to the [BMIm]CI (5 min addition). Within 2 min, the cellulose was finely dispersed in the ionic liquid.
  • the flask was placed under vacuum. After ca. 1 h, there were no visible cellulose particles; the solution viscosity was very high and the solution started climbing the stir rod. The solution was left stirring overnight at 80 0 C under vacuum.
  • Figure 12 is a plot of absorbance versus time for Example 6 and it shows the dissolution of presoaked water wet cellulose (1046 cm “1 ) and the removal of residual water (1635 cm “1 ) from the mixture during the course of the dissolution.
  • the dissolution of the water wet (activated) cellulose was very rapid (60 min) despite the presence of a significant amount of water and the use of 15 wt% cellulose. Even more surprising was the rapid removal of water (ca. 2 h) at this high cellulose concentration.
  • Figure 13 is a plot of absorbance versus time for Example 6 and it illustrates the acetylation of cellulose (1756, 1741 , 1233 cm “1 ), the consumption Of Ac 2 O (1822 cm “1 ), and the coproduction of acetic acid (1706 cm “1 ) during the experiment.
  • the DS values shown in Figure 13 were determined by NMR spectroscopy and correspond to the samples removed during the course of the contact period.
  • acetic anhydride could be easily mixed into the cellulose solution at 100 0 C.
  • the higher reaction temperature led to an increase in reaction rate.
  • the molecular weights (ca. 20,000) of the cellulose acetate samples (Table 2, below) were notably lower that that observed in Examples 1 , 2, and 3 (Table 1, above) were the cellulose was dried prior to use; the polydispersities for the samples of Example 6 are also less than 2.
  • To the flask added 58.79 g of 1-butyl-3-methylimidazolium chloride.
  • the IL Prior to adding the [BMIm]CI, the IL was melted at 90 0 C then stored in a desiccator.
  • the flask was placed in an oil bath and heated to 80 0 C. After reaching 80 0 C, began collecting IR spectra before adding 1.82 g (3 wt%) of glacial acetic acid.
  • This example shows that significant amount of a miscible cosolvent such as a carboxylic acid compatible with cellulose acylation can be mixed with a cellulose-ionic liquid sample while still maintaining cellulose solubility.
  • a cosolvent has the added benefit of reducing solution viscosity.
  • To the flask added 149.7 g of 1-butyl-3-methylimidazolium chloride.
  • the flask was placed in an oil bath and heated to 80 0 C.
  • Microcrystalline cellulose (12.14 g, 7.5 wt%, DP ca. 335) was added to 68.9 g of water. After hand mixing, the cellulose was allowed to stand in the water for 45 min at 60 0 C before filtering which gave 24.33 g of a wet cellulose cake.
  • the water wet cellulose was then added in small portions to the [BMIm]CI (5 min addition). Approximately 15 min after adding the cellulose to the [BMIm]CI, the flask was placed under vacuum by gradually lowering the vacuum starting at ca. 120 mm Hg to ca. 1.4 mm Hg. After ca. 85 min, there were no visible cellulose particles; IR spectroscopy indicated that all of the cellulose was dissolved. The solution was left stirring overnight at 80 0 C under vacuum.
  • the DS increased (until water was added) and the Mw decreased. Fifty-seven minutes after starting the contact period, the cellulose acetate sample had a DS of 2.56 and a Mw of 21 ,736. Prior to adding the MeOH/water, the DS was 2.73 and the Mw was 20,452. After the water contact period, the isolated cellulose acetate had a DS of 2.59 and a Mw of 21 ,005 indicating that the DS was reduced but the Mw was unchanged.
  • To the flask added 60.47 g of 1-allyl-3-methylimidazolium chloride.
  • the flask was placed in an oil bath and heated to 80°C.
  • Microcrystalline cellulose (9.15 g, 7 wt%, DP ca. 335) was added to 27.3 g of water. After hand mixing, the cellulose was allowed to stand in the water for 50 min at 60 0 C before filtering which gave 9.44 g of a wet cellulose cake.
  • the water wet cellulose was then added in small portions to the [AMIm]CI (5 min addition). Approximately 15 min after adding the cellulose to the [AMIm]CI, the flask was placed under vacuum by gradually lowering the vacuum starting at ca. 120 mm Hg. After ca. 40 min, there were no visible cellulose particles; IR spectroscopy indicated that all of the cellulose was dissolved. The solution was left stirring overnight at 80 0 C under vacuum.
  • Example 9 Five minutes after starting the reaction, the first cellulose acetate sample had a DS of 1.74 and a Mw of 36,192. With increasing contact time, the DS increased and the Mw decreased. After 109 min, the DS was 2.82 and the Mw was 30,808. This example shows that, compared to the conventional method of Example 11 (5 eq Ac 2 O, 6.5 h contact time), the method of Example 9 provides for a higher DS and a significant reduction in cellulose acetate molecular weight.
  • Example 11 For example, the conventional method of Example 11 requires 6.5 h to provide a cellulose acetate with a DS of 2.42 and a Mw of 50,839 while in Example 9, a cellulose acetate with a DS of 2.48 and a Mw of 31 ,811 was achieved in 15 min.
  • a solution of cellulose (5 wt%) dissolved in 29.17 g of [BMIm]CI was heated to 80 0 C with an oil bath. The solution was held under vacuum (ca. 7 mm Hg) while stirring for 2 h. To the cellulose solution was added 4.6 g (5 eq) Of Ac 2 O (5 min addition). During the course of the reaction, the solution color became gradually darker (brown). After 2.5 h, the solution had gelled so the contact solution was allowed to cool to room temperature. The product was isolated by adding the solution to water then homogenizing to give a dispersed gel/powder. The mixture was filtered and washed extensively with water.
  • the vials were then placed in an ultrasonic bath (VWR, model 75HT) and ultrasonicated at room temperature for 30-120 min then removed and vortexed (VWR minivortexer) at room temperature using a speed setting of 10. If the cellulose acetate appeared to be dissolving but the rate of dissolution appeared to be slow, the vial was placed on a roller and mixed (ca. 15 revolutions per min) overnight at ambient temperature. Following the mixing period, the solubility of each cellulose acetate was rated as follows:
  • Cellulose acetates with a rating of 1 are very useful in all applications in which acetone solubility or solubility in related solvents (e.g. diethyl phthalate) is a critical factor (e.g. solvent spinning of acetate fiber or melt processing of plasticized cellulose acetate).
  • Cellulose acetates with a rating of 2 or 3 would require additional filtration to remove insoluble particles and/or the use of co- solvents before they would have utility.
  • Cellulose acetates with a rating of 4-6 would not have utility in these applications.
  • cellulose acetates with a rating of 1 are highly desired.
  • Example 1-2 (no secondary component) has a DS of 2.25 and this cellulose acetate forms a gel in acetone while Examples 8-3 and 9-2 (includes secondary component) have a DS of 2.24 and these cellulose acetates yield transparent acetone solutions.
  • the liquid was extracted with two 300 ml_ portions of EtOAc.
  • the liquid was concentrated first at 60 0 C, 20-50 mm Hg then at 90°C, 4 mm Hg leading to 297.8 g of a pale yellow oil.
  • Proton NMR confirmed the formation of the [BMIm]OAc which, by XRF, contained 0.026wt% sulfur.
  • the DS of the CA made using the high sulfur [BMIm]OAc as solvent was higher and the molecular weight lower relative to the CA made using the low sulfur [BMIm]OAc as solvent.
  • the DS did not increase significantly above that observed after 1.5 h contact time at room temperature regardless of which [BMIm]OAc was used as the solvent.
  • Another notable feature of this example was the color of the solutions and products.
  • the contact solution involving high sulfur [BMIm]OAc solvent was black at all temperatures while the contact solution involving low sulfur [BMIm]OAc solvent retained the straw color typical of these solutions prior to the addition of the anhydride.
  • the CA solids obtained from the high sulfur [BMIm]OAc solvent were brown to black in appearance while the CA solids obtained from the low sulfur [BMIm]OAc solvent were white and provided colorless solutions upon dissolution in an appropriate solvent.
  • the remaining contact mixture was then heated to 50 0 C and held at that temperature for 1.6 h before removing a small amount of the solution which was poured into MeOH to precipitate the cellulose acetate.
  • the remaining contact mixture was then heated to 80 0 C and held at that temperature for 1.5 h before allowing the solution to cool and adding 60 ml_ of MeOH to precipitate the cellulose acetate. All three samples were washed extensively with MeOH then dried at 50 0 C, 5 mm Hg overnight.
  • Figure 16 shows a plot of wt% acetic acid versus time as determined by infrared spectroscopy; the final concentration of acetic acid was confirmed by 1 H NMR. Figure 16 shows that in all cases, the reactions were complete within 9-10 h. The most significant factor affecting the rates and extend of reaction was the number of molar equivalents of MeOH. The wt% acetic acid remaining in the [BMIm]OAc ranged from 7.4 wt% to 2.2 wt%.
  • the rotor was placed in a Anton Paar Synthos 3000 microwave and the cellulose-[BMIm]OAc mixtures were heated to 100 0 C using a 3 min ramp and held for 10 min before heating to 120 0 C using a 3 min ramp and held for 5 min. Inspection of each vessel indicated that the cellulose in each example was dissolved in the [BMIm]OAc.
  • This example shows that excess residual carboxylic acid in ionic liquids can be reduced by the method of Example 27 and that the recycled ionic liquid can then be used to dissolve cellulose so that the solutions can be used for preparing cellulose esters.
  • This example also shows that cellulose can be dissolved in an ionic liquid containing up to about 15 wt% carboxylic acid.
  • the mixture was stirred for ca. 75 minutes to allow the Zn(OAc) 2 to dissolve before slowly adding 33.3 g (10 wt%) of previously dried cellulose (DP ca. 335) over a 26 min period.
  • the mixture was stirred at room temperature for ca. 4 h at which time no particles or fiber were visible in the translucent solution; infrared spectroscopy indicated that all of the cellulose was dissolved ( Figure 18).
  • the solution was heated to 80 0 C. By the time the temperature reached 60 0 C, the translucent solution was completely clear. After reaching 80 0 C, the solution was cooled to room temperature.
  • This example shows that cellulose triacetate can rapidly be prepared from cellulose dissolved in ionic liquids. This example also shows that excess carboxylic acid can be removed from the ionic liquid and the recycled ionic liquid can be recovered in high yield. The recycled ionic liquid can then be used to dissolve cellulose so that the solutions can be used again for preparing cellulose esters.
  • the reaction was sampled (Figure 25) throughout the contact period by removing 6-10 g aliquots of the reaction mixture and precipitating in 100 ml_ of MeOH. The solid from each aliquot was washed once with a 100 ml_ portion of MeOH then twice with 100 ml_ of MeOH containing 8 wt% of 35 wt% H 2 O 2 . The samples were then dried at 6O 0 C, 5 mm Hg overnight.
  • the major resonances in the top spectrum centered near 5.04, 5.62, 4.59, 4.29, 4.04, 3.73, and 3.69 correspond to trisubstituted monomers.
  • the bottom spectrum there are much less of these resonances relative to the other type of monomer resonances.
  • the extent and the size of the block segments will depends upon factors such as mixing, prior water treatment or no water treatment of the cellulose, concentration and type of catalyst, contact temperature, and the like.
  • 3 samples were taken prior to the addition of water. These 3 samples ranged in DS from 2.48-2.56 and at 10 wt% in acetone, they were soluble giving slightly hazy solutions (solubility rating of 2). In contrast, the 2 samples taken after water addition (DS ca. 2.52) were insoluble in acetone (solubility rating of 6).
  • Figure 27 compares the ring proton resonances for cellulose acetates prepared from cellulose dissolved in [BMIm]OAc before and after addition of water.
  • the differences between these 2 spectra are consistent with different monomer compositions in the copolymers.
  • the solids were washed by taking them up in 300 ml_ of MeOH and stirring the slurry for ca. 1 h before the solids were isolated by filtration.
  • the solids were twice taken up in 300 mL of 12/1 MeOH/35% H 2 O 2 and the slurry was stirred for ca. 1 h before the solids were isolated by filtration.
  • the solids were then dried overnight at 50 0 C, ca. 20 mm Hg.
  • cellulose triacetate can rapidly be prepared from cellulose dissolved in [EMIm]OAc.
  • Cellulose triacetate can be used to prepare film useful in liquid crystalline displays and photographic film base.
  • the product was precipitated in 350 ml_ of MeOH and the slurry was stirred for ca. 1 h before the solids were isolated by filtration.
  • the solids were washed by taking them up in 300 ml_ of MeOH and stirring the slurry for ca. 1 h before the solids were isolated by filtration. Twice, the solids were taken up in 300 ml_ of 12/1 MeOH/35% H 2 O 2 and the slurry was stirred for ca. 1 h before the solids were isolated by filtration.
  • the solids were then dried overnight at 5O 0 C, ca. 20 mm Hg which gave 1.68 g of a white solid.
  • Analysis by 1 H NMR revealed that the solid was a cellulose acetate with a DS of 2.67.
  • This example shows that a cellulose solution in an ionic liquid can be contacted with an immiscible or sparingly soluble co-solvent without causing precipitation of the cellulose.
  • an acylating reagent Upon contact with an acylating reagent, the cellulose is esterified changing the solubility of the now cellulose ester- ionic liquid solution with the formerly immiscible co-solvent so that the contact mixture becomes a single phase.
  • the resulting single phase has much lower solution viscosity than the initial cellulose-ionic liquid solution.
  • the discovery also provides a means to process highly viscous cellulose-ionic liquid solutions at lower contact temperatures.
  • the cellulose ester product can be isolated from the new single phase by conventional means.
  • the cellulose ester product has desirable degrees of substitution, molecular weights, and solubility in solvents such as acetone, and can be readily melt processed when plasticized with plasticizers such as diethyl phthalate and the like.
  • a 3-neck 100 ml_ round bottom flask containing 28.84 g of a 5 wt% cellulose solution in [BMIm]CI was equipped for mechanical stirring and with an N 2 /vacuum inlet.
  • the flask was placed in a preheated 8O 0 C oil bath and the flask contents were placed under vacuum (ca. 7 mm Hg) for 2 h.
  • To the solution was added 25 mL of methyl ethyl ketone that had been previously dried over 4A molecular sieves resulting in two well defined phases.
  • To the biphasic mixture was added 4.54 g of Ac 2 O while stirring vigorously. After ca. 75 min, the contact mixture appeared to be homogeneous.
  • the contact mixture was allowed to cool to room temperature. Phase separation did not occur even when a small amount of water and methyl ethyl ketone was added to the homogeneous mixture.
  • the product was isolated by addition of the contact mixture to 200 mL of MeOH followed by filtration to separate the solids. The solids were washed twice with MeOH and three times with water before they were dried at 50 0 C, ca. 5 mm Hg. Analysis by 1 H NMR and by GPC revealed that the product was a cellulose acetate with a DS of 2.11 and Mw of 50,157.
  • Example 36 Color measurements for cellulose esters prepared from cellulose dissolved in ionic liquids.
  • Example of a general method for bleaching cellulose esters while dissolved in ionic liquid To a 7.5 wt% solution of cellulose dissolved in [BMIm]CI was added a mixture of 2.9 eq Ac 2 O and 0.1 eq MSA. After 65 minutes, in situ IR indicated that the reaction was complete. To the solution was added a bleaching agent (in this case, 0.75 wt% of a 2.25 wt% solution of KMnO 4 dissolved in MeOH). The mixture was stirred for 2 h before the cellulose ester was isolated by precipitation in water, washed with water, and dried. The concentration of bleaching agent and bleaching contact time depends upon the particular process.
  • Example of a general method for bleaching cellulose esters after separation from the ionic liquid After completing the reaction, the cellulose ester is isolated from the ionic liquid by precipitation in a nonsolvent such as water or alcohol. The liquids are separated from the cellulose ester and, optionally, the cellulose ester can be washed further before contacting the solid product with a bleaching agent (e.g. 35 wt% aqueous H 2 O 2 ). Specific examples of this process can be found in Examples 33 and 34. The concentration of bleaching agent, the number of bleaching cycles, and bleaching contact time depends upon the particular process.
  • a bleaching agent e.g. 35 wt% aqueous H 2 O 2
  • This example illustrates that contacting a cellulose ester with a bleaching agent while dissolved in ionic liquid or after separation of the cellulose ester from the ionic liquid can lead to very significant improvements in color.
  • Example 37 Viscosity of solutions of cellulose dissolved in ionic liquids containing miscible cosolvents.
  • [00302] Solutions of cellulose dissolved in [BMIm]CI containing different levels of acetic acid were prepared by the following general procedure: To a 3-neck 50 ml_ round bottom flask equipped for mechanical stirring and with a N2/vacuum inlet was added [BMIm]CI. The flask contents were heated to 80 0 C and placed under vacuum (0.8 mm Hg). After 1.7 h, 5 wt% acetic acid was added to the [BMIm]CI before allowing the solution to cool to room temperature. Cellulose (5 wt%) was added to the solution before heating the mixture to 80 0 C. The mixture was stirred until a homogeneous solution was obtained (ca. 80 min), The solution was then cooled to room temperature.
  • Figure 28 compares the viscosities of cellulose solutions containing no acetic acid, 5 wt% acetic acid, and 10 wt% acetic acid at 25, 50, 75, 100 0 C.
  • the viscosity of the cellulose-[BMIm]CI-5 wt% acetic acid solution is significantly less than that of cellulose-[BMIm]CI at all temperatures. For example, at 25 0 C and 0.2 rad/sec the viscosity of the cellulose-[BMIm]CI-5 wt% acetic acid solution is 466 poise versus 44,660 poise for the cellulose- [BMIm]CI solution.
  • the viscosities of the cellulose-[BMIm]CI-10 wt% acetic acid, cellulose-[BMIm]CI-5 wt% acetic acid, and cellulose-[BMIm]CI solutions are 22,470, 466, and 44,660 poise, respectively.
  • the differences in the viscosities between the cellulose-[BMIm]CI-10 wt% acetic acid and cellulose-[BMIm]CI solutions diminish and the observed viscosities depend upon the shear rate.
  • This example shows that the viscosity of a cellulose-ionic liquid solution can be dramatically altered by adding a miscible cosolvent such as a carboxylic acid to the solution. The viscosity drops with increasing miscible cosolvent reaching a minimum before increasing again as addition cosolvent is added.
  • Example 38 Viscosity of solutions of cellulose dissolved in ionic liquids containing immiscible cosolvents.
  • Figure 29 compares the solution viscosity of the contact mixtures with and without cosolvents at 25 0 C. Inclusion of a cosolvent dramatically reduces the viscosity of the solution. For example at 25 0 C and 1 rad/sec, inclusion of methyl ethyl ketone resulted in a solution with a viscosity of 24.6 poise versus 6392 poise for the solution without methyl ethyl ketone.
  • Example 39 Impact of miscible cosolvents on reaction rates and total DS.
  • a 3-neck 100 ml_ round bottom flask was equipped with a double neck adapter giving four ports, an iC10 diamond tipped IR probe, for mechanical stirring, and a N 2 /vacuum inlet.
  • To the flask was added 50.15 g of 1-butyl-3-methylimidazolium propionate ([BMIm]OPr).
  • cellulose 4.07 g, 7.5 wt%) was added to the [BMIm]OPr at room temperature.
  • Vacuum was applied with the aid of a bleed valve.
  • a preheated 80 0 C oil bath was raised to the flask. A clear solution was obtained 8 min after raising the oil bath. Stirring was continued for an additional 2.8 h before the solution was allowed to cool to room temperature and stand under N 2 for 12 h.
  • Figure 30 shows a plot of absorbance for a band at 1212 cm "1 (propionate ester and propionic acid) versus contact time.
  • the DS indicated in Figure 30 correspond to the DS values for the samples obtained in each experiment. Relative to the reaction of cellulose dissolved in [BMIm]OPr (no propionic acid), the reaction rate of cellulose dissolved in [BMIm]OPr + 11.9 wt% propionic acid is slower and the DS of each sample is higher than the corresponding sample in the other experiment.
  • this example shows in addition to impacting solution viscosity, a cosolvent can also have a dramatic impact on reaction rates and total DS obtained.
  • Example 40 Regioselective esterification of cellulose dissolved in ionic liquids by the controlled addition of anhydrides.
  • Figure 31 is a plot of absorbance versus time for series 1 , and it illustrates the esterification of cellulose (1756, 1233, 1212 cm “1 ), the consumption of anhydride (1815 cm '1 ), and the coproduction of carboxylic acid (1706 cm '1 ) during the experiment.
  • the DS values shown in Figure 31 were determined by proton NMR spectroscopy and correspond to the samples removed during the course of the contact period.
  • the change in the acetyl methyl (centered near 1.9 ppm) and propionyl methyl (centered near 1.0 ppm) resonances (Figure 32) clearly indicated a nonrandom distribution of the acyl substituents.
  • the RDS Pr at C 6 was 0.56 and the RDS Ac at C 6 was 0.44.
  • the RDS for propionate and acetate were roughly equivalent.
  • the RDSp r was 0.20 and the RDSA C was 0.30.
  • the propionate carbonyl C 6 ZC 2 and C 6 ZC 2 ratios were large (1.6 and 2.8, respectively) as were the propionate carbonyl C ⁇ ZC 3 *DS (1.7) and C 6 ZC ⁇ DS (3.1) values.
  • FIG. 34 shows a plot of DS versus glass transition temperature (Tg) for the polymers prepared in series 1-3.
  • Tg glass transition temperature
  • the Tg for series 1 is shifted 5 0 C lower relative to series 2.
  • the Tg for series 2 is shifted 5 0 C lower relative to series 3. That is, the Tg can be shifted as much as 10 0 C at a constant DS by controlling the placement of the acyl substituents.
  • FIG 35 shows a plot of DSp r versus Tg for the same series 1-3.
  • Example 41 Casting of film and film optical measurements using cellulose esters containing a minor amount (DS ⁇ 0.2) of a second acyl group.
  • the cellulose esters in examples 41.4 and 41.5 are essentially 2,3- regioselectively substituted and differs from the examples of the present invention in that they have a low RDS at C 6 while the cellulose esters of the present invention have a high RDS at C 6 .
  • the ring RDS was determined for each sample before film was cast and the film optical properties determined. The results are summarized in Table 11.
  • Examples 41.1 and 41.2 are essentially identical except that Example 41.1 was a cellulose acetate, and Example 41.2 was a cellulose propionate. As shown in Table 11 , the cellulose propionate had a higher R th (+36 nm) relative to the cellulose acetate (-56 nm).
  • Example 42 Casting of film and film optical measurements using cellulose esters containing a second acyl group (DS ⁇ 0.2).
  • cellulose ester was a cellulose acetate propionate that was prepared by the general procedures described in US 2009/0096962 and US 2009/0050842 and is available from Eastman Chemical Company. The ring and carbonyl RDS were determined for each sample before film was cast, and the film optical properties were determined.
  • Table 12 provides the ring RDS versus Rth
  • Table 13 provides the carbonyl RDS versus R th
  • Table 14 provides the propionate and acetate ratios of C 6 IC 3 and C 6 IC 2 as well as C 6 /C 3 * DS and C 6 /C 2 * DS.
  • Table 12 The degree of substitution, relative degree of substitution, and out-of-plane retardation (nm) for compensation film for cellulose esters containing a second acyl group (DS ⁇ 0.2) prepared by the methods of the present invention from cellulose dissolved in [BMIm]CI versus comparative (C) cellulose esters.
  • Examples 42.1-42.6 had high ring RDS C 6 ZC 3 and C 6 ZC ⁇ ratios but there was variation in R th at similar total DS values.
  • Examples 42.6 and 42.2 had similar DS values but significantly different R th values (-157 nm versus -54 nm).
  • Example 42.4 had a lower DS (2.61) than did Example 42.5 (2.77), but yet the R th value for Example 42.4 (- 17 nm) was less negative than Example 42.5 (-34 nm).
  • examination of the carbonyl RDS C 6 /C 3 and C 6 ZC 2 ratios for these two Examples revealed that Example 42.4 had a much higher C 6 ZC 3 and C 6 IC 2 Pr RDS than did Example 42.5. That is, having propionate at C 6 with a high C 6 ZC 3 and C 6 ZC 2 Pr RDS ratios had a significant influence on R th -
  • Example 41 single acyl substituent
  • a propionate substituent increased R th more that an acetate substituent at an equivalent DS and substitution pattern and that the total hydroxyl DS had a significant influence on the R th values.
  • the regioselectively substituted cellulose esters provided for a much wider range of R th relative to other substitution patterns.
  • the present Example illustrated the influence that a second acyl group can have on R th values. That is, for regioselectively substituted cellulose esters of the present invention, the combination of acetyl and propionyl substituents led to a narrower and less negative R th range relative to conventional cellulose esters. Higher propionate DS and high C 6 ZC 3 and C 6 ZC 2 Pr RDS ratios at equivalent total DS served to further modify R th -

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
PCT/US2009/004637 2008-08-13 2009-08-13 Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom Ceased WO2010019244A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN200980131585.8A CN102124031B (zh) 2008-08-13 2009-08-13 羧基化离子液体方法制备的区域选择性取代的纤维素酯以及由此制备的产物
EP17172680.5A EP3239179B1 (en) 2008-08-13 2009-08-13 Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom
JP2011522997A JP2011530643A (ja) 2008-08-13 2009-08-13 カルボキシル化イオン液体法において製造される位置選択的に置換されたセルロースエステルおよびそれから製造される製品
EP09789131A EP2313439A1 (en) 2008-08-13 2009-08-13 Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8842308P 2008-08-13 2008-08-13
US61/088,423 2008-08-13
US12/539,800 2009-08-12
US12/539,800 US9834516B2 (en) 2007-02-14 2009-08-12 Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom

Publications (1)

Publication Number Publication Date
WO2010019244A1 true WO2010019244A1 (en) 2010-02-18

Family

ID=41059941

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/004637 Ceased WO2010019244A1 (en) 2008-08-13 2009-08-13 Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom

Country Status (6)

Country Link
US (2) US9834516B2 (enExample)
EP (2) EP2313439A1 (enExample)
JP (1) JP2011530643A (enExample)
KR (1) KR20110043757A (enExample)
CN (3) CN103923352B (enExample)
WO (1) WO2010019244A1 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013532311A (ja) * 2010-07-02 2013-08-15 イーストマン ケミカル カンパニー 逆光学分散を有する多層セルロースエステルフィルム
CN103459428A (zh) * 2011-03-30 2013-12-18 独立行政法人理化学研究所 纤维素衍生物的酯化物及其制造方法
CN103534274A (zh) * 2011-04-13 2014-01-22 伊士曼化工公司 纤维素酯光学膜
EP3216806A1 (en) * 2009-04-15 2017-09-13 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom
US9964667B2 (en) 2013-12-17 2018-05-08 Eastman Chemical Company Cellulose ester based quarter wave plates having normal wavelength dispersion
EP2313438B1 (en) * 2008-08-13 2019-09-18 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9834516B2 (en) 2007-02-14 2017-12-05 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom
US10174129B2 (en) 2007-02-14 2019-01-08 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom
US8153782B2 (en) * 2007-02-14 2012-04-10 Eastman Chemical Company Reformation of ionic liquids
US8158777B2 (en) 2008-02-13 2012-04-17 Eastman Chemical Company Cellulose esters and their production in halogenated ionic liquids
US20090203900A1 (en) * 2008-02-13 2009-08-13 Eastman Chemical Comapany Production of cellulose esters in the presence of a cosolvent
US9777074B2 (en) 2008-02-13 2017-10-03 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom
US8188267B2 (en) * 2008-02-13 2012-05-29 Eastman Chemical Company Treatment of cellulose esters
US20100023341A1 (en) * 2008-05-29 2010-01-28 Reel Drinks Llc Method for rule-based gift giving
US8676704B2 (en) 2008-03-13 2014-03-18 Giftya Llc Method for transferring funds
JP2011074113A (ja) * 2009-09-29 2011-04-14 Toray Ind Inc セルロース混合エステルおよびその製造方法
US8980050B2 (en) 2012-08-20 2015-03-17 Celanese International Corporation Methods for removing hemicellulose
US8888993B2 (en) 2010-07-30 2014-11-18 Chevron U.S.A. Inc. Treatment of a hydrocarbon feed
US11012480B2 (en) 2010-09-13 2021-05-18 Jeffrey W. Mankoff Modifying signal associations in complex computing networks
CN102441433B (zh) * 2011-09-13 2014-07-30 昆明理工大学 一种离子液催化剂及其催化生物质废弃物液化气化的方法
US20130178614A1 (en) 2011-10-25 2013-07-11 Virginia Tech Intellectual Properties, Inc. Regioselectively substituted cellulose esters and efficient methods of preparing them
US20140048221A1 (en) 2012-08-20 2014-02-20 Celanese International Corporation Methods for extracting hemicellulose from a cellulosic material
US9939554B2 (en) * 2013-01-24 2018-04-10 Akron Polymer Systems, Inc. Wide-view optical film having reversed wavelength dispersion
CN103588883A (zh) * 2013-11-22 2014-02-19 南开大学 一种基于离子液体的改性纤维素膜材料的制作方法
US9309362B2 (en) 2013-12-17 2016-04-12 Eastman Chemical Company Optical films containing optical retardation-enhancing additive
US20160044955A1 (en) 2014-08-13 2016-02-18 R.J. Reynolds Tobacco Company Smokeless tobacco products
WO2016068053A1 (ja) * 2014-10-27 2016-05-06 国立大学法人金沢大学 多糖類誘導体及びリグニン誘導体の製造方法
WO2016139356A1 (en) * 2015-03-05 2016-09-09 Albert Ludwigs Universität Freiburg Ionic-liquid mediated production of cellulose nanocrystals directly from wood, grass or bioresidues
US9605086B2 (en) * 2015-03-26 2017-03-28 Fuji Xerox Co., Ltd. Resin composition and resin molded article
JP6582485B2 (ja) * 2015-03-27 2019-10-02 セイコーエプソン株式会社 組成物、造形物の製造方法および造形物
JP2016188283A (ja) 2015-03-30 2016-11-04 セイコーエプソン株式会社 組成物セット、造形物の製造方法および造形物
CN105175760B (zh) * 2015-07-16 2018-12-04 广西科开成林科技有限公司 一种醋酸丁酸纤维素膜的制备方法
CN105527755A (zh) * 2016-02-18 2016-04-27 武汉华星光电技术有限公司 彩膜基板以及液晶显示面板
US10293584B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
US10300682B2 (en) 2016-03-11 2019-05-28 Solutia Inc. Cellulose ester multilayer interplayers
US10293583B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
CN109070553B (zh) 2016-03-11 2021-02-26 首诺公司 纤维素酯多层夹层
US10195826B2 (en) 2016-03-11 2019-02-05 Solutia Inc. Cellulose ester multilayer interlayers
US10293585B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
US10293580B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
US10293582B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
US10293579B2 (en) 2016-03-11 2019-05-21 Solutia Inc. Cellulose ester multilayer interlayers
US10640577B2 (en) 2016-04-22 2020-05-05 Eastman Chemical Company Regioselectively substituted cellulose esters and films made therefrom
US20200017606A1 (en) * 2017-03-29 2020-01-16 Eastman Chemical Company Regioselectively substituted cellulose esters
WO2019055267A1 (en) 2017-09-12 2019-03-21 Solutia Inc. LAMINATED GLASS AND INTERMEDIATE LAYERS COMPRISING CELLULOSE ESTERS
JP2019218468A (ja) * 2018-06-20 2019-12-26 株式会社ダイセル セルロースベンゾエート
CN109734817B (zh) * 2018-12-29 2021-05-18 青岛科技大学 一步合成水溶性醋酸纤维素的方法
CN111718425B (zh) * 2019-03-20 2021-09-17 中国科学院化学研究所 一种可熔融加工的纤维素酯及其制备方法与应用
CN110066345B (zh) * 2019-04-11 2020-07-14 中国科学院化学研究所 一种多糖酯的制备方法
US12492298B2 (en) * 2019-08-26 2025-12-09 Eastman Chemical Company 2-ethylhexanoyl substituted cellulose esters
TWI879887B (zh) 2020-02-13 2025-04-11 美商伊士曼化學公司 以經位向選擇取代的纖維素酯為主之具有改良波長色散之負雙折射補償膜
CN113005634B (zh) * 2021-02-24 2022-07-19 苏州鱼得水电气科技有限公司 一种吸湿抑菌的水刺无纺布及其制备方法
WO2023018604A1 (en) 2021-08-11 2023-02-16 Eastman Chemical Company Regioselectively substituted cellulose ester based negative birefringent compensation films having improved wavelength dispersion
WO2023175787A1 (ja) * 2022-03-16 2023-09-21 国立大学法人金沢大学 イオン液体の回収方法
WO2023175788A1 (ja) * 2022-03-16 2023-09-21 国立大学法人金沢大学 イオン液体の回収方法
JP2025104846A (ja) * 2023-12-28 2025-07-10 広栄化学株式会社 エステル化多糖類の製造方法
JP2025133236A (ja) * 2024-03-01 2025-09-11 国立大学法人神戸大学 イオン液体中の着色成分の除去
JP2025133235A (ja) * 2024-03-01 2025-09-11 国立大学法人神戸大学 イオン液体中のセルロース由来不純物の除去

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005089689A (ja) * 2003-09-19 2005-04-07 Fuji Photo Film Co Ltd セルロース組成物、セルロースフィルム、およびセルロースフィルム用の改質剤
WO2006013869A1 (en) * 2004-08-04 2006-02-09 Fujifilm Corporation Thermoplastic film and method of producing the same
JP2006232959A (ja) * 2005-02-24 2006-09-07 Fuji Photo Film Co Ltd セルロースアシレートフィルム、位相差板、偏光板、液晶表示装置およびセルロースアシレートフィルムの製造方法
WO2007111339A1 (en) * 2006-03-20 2007-10-04 Fujifilm Corporation Cellulose acylate film and method for producing same, and retardation film, polarizer and liquid crystal display device comprising the film
WO2007144282A1 (de) * 2006-06-16 2007-12-21 Basf Se Verfahren zur acylierung von cellulose
WO2008000666A1 (de) * 2006-06-30 2008-01-03 Basf Se Verfahren zur acylierung von cellulose mit gezieltem durchschnittlichen polymerisationsgrad
EP1911792A1 (en) * 2005-05-24 2008-04-16 FUJIFILM Corporation Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same
WO2008100566A1 (en) * 2007-02-14 2008-08-21 Eastman Chemical Company Cellulose esters and their production in carboxylated ionic liquids
WO2008143765A2 (en) * 2007-05-14 2008-11-27 Eastman Chemical Company Cellulose esters with a high hydroxyl content and their use in liquid crystal displays
WO2009029220A1 (en) * 2007-08-24 2009-03-05 Eastman Chemical Company Mixed cellulose esters having low bifringence and films made therefrom
WO2009102305A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Treatment of cellulose esters
WO2009102307A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Production of cellulose esters in the presence of a cosolvent
WO2009102306A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Cellulose esters and their production in halogenated ionic liquids

Family Cites Families (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2563506A (en) 1951-08-07 Quaternary ammonium salts of
US2083A (en) * 1841-05-06 And cleaning out docks
US787994A (en) * 1901-05-08 1905-04-25 Walter P Sawyer Harness-saddle.
US1996754A (en) 1928-09-26 1935-04-09 Celanese Corp Improving the color of cellulose derivatives
US1943176A (en) 1930-09-27 1934-01-09 Chem Ind Basel Cellulose solution
US1924238A (en) 1930-09-27 1933-08-29 Chem Ind Basel Cellulose solution and cellulose derivative and process of making same
GB581046A (en) 1943-07-27 1946-09-30 British Celanese Improvements in bleaching organic acid esters of cellulose
GB572017A (en) 1943-10-04 1945-09-19 Henry Dreyfus Improvements relating to coating and impregnating compositions
GB611665A (en) 1945-05-03 1948-11-02 British Celanese Improvements in the production of cellulose esters
US2651629A (en) 1949-07-01 1953-09-08 Celanese Corp Cellulose esters
GB736964A (en) 1951-05-17 1955-09-14 Hercules Powder Co Ltd Improvements in or relating to the treatment of cellulose esters
US3042408A (en) 1957-07-05 1962-07-03 Kenneth G Johnson Game
US3042508A (en) 1959-05-28 1962-07-03 Stanley Works Non-loading metal-backed abrader and method for its production
US3038708A (en) 1959-11-02 1962-06-12 Willard H Rice Humidifier
GB1139616A (en) 1967-04-17 1969-01-08 Teijin Ltd Process for producing bleached and purified cellulose acetate
DE2262829C3 (de) 1972-12-22 1980-05-14 Haarmann & Reimer Gmbh, 3450 Holzminden Rauchbare Produkte
CA1071464A (en) 1975-02-13 1980-02-12 Carlton K. Bergsbaken Dried soft curd cheese
US4028132A (en) 1975-11-25 1977-06-07 International Playtex, Inc. Cellulose solutions and products prepared therefrom
US4189761A (en) 1977-08-12 1980-02-19 Sprague Electric Company Non-aqueous electrolytic capacitor electrolyte
US4278790A (en) 1978-07-31 1981-07-14 Hopkins Agricultural Chemical Co. Novel cellulose solutions
JPS56162617A (en) 1980-05-20 1981-12-14 Fuji Photo Film Co Ltd Preparation of film
US4557951A (en) 1983-11-22 1985-12-10 A. E. Staley Manufacturing Company Cellulosic organic solvent soluble products
JPS60144332A (ja) 1983-12-26 1985-07-30 Tachikawa Kenkyusho 有機溶媒にセルロ−スを溶解する方法
US4501888A (en) 1984-01-24 1985-02-26 A. E. Staley Manufacturing Company Process for producing esters of carbohydrate materials
EP0330106A1 (de) 1988-02-25 1989-08-30 Akzo Nobel N.V. Modifizierte Cellulose für biocompatible Dialysemembranen II und Verfahren zu deren Herstellung
DE4000092C2 (de) * 1990-01-03 1994-01-13 Mauricio Kling Rotorlagerungsanordnung für eine Windkraftmaschine
DE4142761A1 (de) 1991-12-23 1993-06-24 Wolff Walsrode Ag Verfahren zur herstellung von methyl-hydroxyalkyl-celluloseethern
JP3419412B2 (ja) 1993-05-21 2003-06-23 三菱瓦斯化学株式会社 第四級アンモニウム有機カルボン酸塩の製造方法
US5750677A (en) 1994-12-30 1998-05-12 Eastman Chemical Company Direct process for the production of cellulose esters
US5876567A (en) 1995-04-28 1999-03-02 Yamamoto; Soichiro Solvent recycling system
US5610233A (en) 1995-08-03 1997-03-11 Eastman Chemical Company Aqueous coating compositions containing cellulose esters
US5977347A (en) 1996-07-30 1999-11-02 Daicel Chemical Industries, Ltd. Cellulose acetate propionate
GB9719551D0 (en) 1997-09-16 1997-11-19 British Nuclear Fuels Plc Treatment of molten salt reprocessing wastes
EP0911656B1 (en) * 1997-10-20 2005-01-26 Fuji Photo Film Co., Ltd. Optical compensatory sheet and liquid crystal display
US7122660B1 (en) 1998-03-17 2006-10-17 Daicel Chemical Industries, Ltd. Cellulose acetate and dope containing the same
ATE276043T1 (de) 1999-05-26 2004-10-15 Biotage Ab Herstellung und verwendung von ionischen flüssigkeiten in mikrowellen-assistierten chemischen umwandlungen
GB0008707D0 (en) 2000-04-07 2000-05-31 Bp Chem Int Ltd Imidazole carbenes
US6500215B1 (en) 2000-07-11 2002-12-31 Sybron Chemicals, Inc. Utility of selected amine oxides in textile technology
JP2002179701A (ja) 2000-12-15 2002-06-26 Fuji Photo Film Co Ltd セルロースアシレート
DE60112229T2 (de) 2000-12-15 2006-01-12 Fuji Photo Film Co., Ltd., Minami-Ashigara Celluloseester einer aromatischen Carbonsäure
KR20030070607A (ko) 2001-01-17 2003-08-30 후지 샤신 필름 가부시기가이샤 셀룰로스 아실레이트 및 이의 용액
EP1285931B1 (en) 2001-03-14 2013-05-15 Daicel Chemical Industries, Ltd. Method for adjusting the degree of substitution with acetyl group of cellulose acetate
JP2002265501A (ja) 2001-03-14 2002-09-18 Fuji Photo Film Co Ltd セルロースアシレート溶液およびセルロースアシレートフイルムの製造方法
JP2002275132A (ja) 2001-03-21 2002-09-25 Japan Carlit Co Ltd:The 高純度四級アンモニウム無機酸塩の製造方法
USH2083H1 (en) 2001-03-27 2003-10-07 Eastman Chemical Company Cellulose acetate film for use in liquid crystal displays
US20030036493A1 (en) 2001-05-01 2003-02-20 The Procter & Gamble Company Stable liquid or gel bleaching composition containing diacyl peroxide particles
EP1266740B1 (en) 2001-06-15 2007-10-31 FUJIFILM Corporation Method of producing of cellulose ester film
DE10145747A1 (de) 2001-09-17 2003-04-03 Solvent Innovation Gmbh Ionische Flüssigkeiten
US6824599B2 (en) 2001-10-03 2004-11-30 The University Of Alabama Dissolution and processing of cellulose using ionic liquids
US6808557B2 (en) 2001-10-03 2004-10-26 The University Of Alabama Cellulose matrix encapsulation and method
US6872766B2 (en) 2001-10-03 2005-03-29 Eastman Kodak Company Ultraviolet light filter element
FR2831171B1 (fr) 2001-10-24 2007-02-02 Rhodia Chimie Sa Procede de preparation d'acide poly-ou copoly-glucuronique
US6827773B2 (en) 2001-10-31 2004-12-07 North Carolina State University Cellulose solvent compositions and methods of making and employing same
US6991718B2 (en) 2001-11-21 2006-01-31 Sachem, Inc. Electrochemical process for producing ionic liquids
AR038161A1 (es) 2002-01-24 2004-12-29 Basf Ag Procedimiento para separar acidos de mezclas de reaccion quimicas con la ayuda de liquidos ionicos
WO2003086605A2 (en) 2002-04-05 2003-10-23 University Of South Alabama Functionalized ionic liquids, and methods of use thereof
US7324180B2 (en) 2002-09-06 2008-01-29 Dai Nippon Printing Co., Ltd. Laminated retardation optical element, process of producing the same, and liquid crystal display
JP2004175785A (ja) 2002-10-04 2004-06-24 Keio Gijuku グリコシル化法と、それに用いるための溶媒及び触媒
CN1261496C (zh) 2002-10-22 2006-06-28 中国科学院化学研究所 一种纤维素溶液及其制备方法
JP4280486B2 (ja) 2002-11-25 2009-06-17 富士フイルム株式会社 溶液製膜方法
CN100424259C (zh) 2002-12-12 2008-10-08 中国科学院化学研究所 一种含不饱和双键的室温离子液体及制备方法和应用
US7585905B2 (en) 2003-03-14 2009-09-08 Eastman Chemical Company Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions
CN100470334C (zh) 2003-03-28 2009-03-18 富士胶片株式会社 液晶显示装置
DE10333239A1 (de) 2003-07-21 2005-03-10 Basf Ag Verfahren zur Herstellung von gereinigten 1,3- substituierten Imidazoliumsalzen
AU2003904323A0 (en) 2003-08-13 2003-08-28 Viridian Chemical Pty Ltd Solvents based on salts of aryl acids
FI115835B (fi) 2003-08-15 2005-07-29 Kemira Oyj Liuotusmenetelmä
FI116142B (fi) 2003-09-11 2005-09-30 Kemira Oyj Esteröintimenetelmä
EP2532684A3 (en) 2003-11-28 2013-03-20 Eastman Chemical Company Cellulose interpolymers and method of oxidation
FI116140B (fi) 2003-12-03 2005-09-30 Kemira Oyj Eetteröintimenetelmä
FI116141B (fi) 2004-01-05 2005-09-30 Kemira Oyj Depolymerointimenetelmä
DE102004003958A1 (de) 2004-01-26 2005-08-11 Basf Ag Herstellungsmethode für ionische Flüssigkeiten
DE102004010662A1 (de) 2004-03-04 2005-09-22 Basf Ag Verfahren zur Herstellung von Verbindungen mit quaternären sp2-hybridisierten Stickstoffatomen
WO2005093476A1 (en) 2004-03-25 2005-10-06 Fuji Photo Film Co., Ltd. Transparent film and optical compensatory film, polarizing plate and liquid-crystal display device employing it
US7888412B2 (en) 2004-03-26 2011-02-15 Board Of Trustees Of The University Of Alabama Polymer dissolution and blend formation in ionic liquids
JP4681245B2 (ja) 2004-03-31 2011-05-11 ダイセル化学工業株式会社 セルロースエステル及びそのフィルム
JP2005307055A (ja) 2004-04-22 2005-11-04 Fuji Photo Film Co Ltd セルロースアシレートの製造方法、セルロースアシレートフイルム、それを用いた光学機能性シート、偏光板、液晶表示装置
US20060004192A1 (en) 2004-07-02 2006-01-05 Fuji Photo Film Co., Ltd. Method of preparing a cellulose acylate, cellulose acylate film, polarizing plate, and liquid crystal display device
CN101039913A (zh) 2004-08-24 2007-09-19 巴斯福股份公司 制备高纯度季铵化合物的方法
JP2008510741A (ja) 2004-08-24 2008-04-10 ビーエーエスエフ ソシエタス・ヨーロピア イオン液体を製造するための出発化合物としてのイミダゾリウム−メチルスルファイト
DE102004043631A1 (de) 2004-09-07 2006-03-09 Basf Ag Verfahren zur Herstellung heterocyclischer quartärer Ammonium- Verbindungen und/oder Guanidinium- Verbindungen hoher Reinheit
DE102004043632A1 (de) 2004-09-07 2006-03-09 Basf Ag Verfahren zur Herstellung heterocyclischer quartärer Ammonium- und/oder Guanidinium-Verbindungen
US20060062749A1 (en) 2004-09-16 2006-03-23 Shelton Michael C personal care products incorporating cellulosic fatty acid esters
JP4108077B2 (ja) 2004-09-22 2008-06-25 ダイセル化学工業株式会社 セルロースエステル及びその製造方法
GB0422447D0 (en) 2004-10-08 2004-11-10 Univ Cambridge Tech Use of ionic liquids
US7737102B2 (en) 2004-11-01 2010-06-15 The Procter & Gamble Company Ionic liquids derived from functionalized anionic surfactants
JP4951750B2 (ja) 2004-11-10 2012-06-13 国立大学法人東京農工大学 難溶性多糖類の溶解剤および該溶解剤と多糖類を含有してなる組成物
JP2006137977A (ja) * 2004-11-11 2006-06-01 Hitachi Metals Ltd 連続溶融金属めっき用ロール
JP4786909B2 (ja) 2005-02-01 2011-10-05 ダイセル化学工業株式会社 セルロース混酸エステル及びその製造方法
JP5160040B2 (ja) 2005-02-28 2013-03-13 千葉製粉株式会社 糖脂肪酸エステルの製造方法
JP2006251439A (ja) 2005-03-11 2006-09-21 Nitto Denko Corp 液晶パネル、液晶テレビおよび液晶表示装置
US7438832B2 (en) 2005-03-29 2008-10-21 Eastman Kodak Company Ionic liquid and electronically conductive polymer mixtures
JP4499594B2 (ja) 2005-03-29 2010-07-07 第一工業製薬株式会社 超高純度イオン性液体
US7550520B2 (en) 2005-05-31 2009-06-23 The University Of Alabama Method of preparing high orientation nanoparticle-containing sheets or films using ionic liquids, and the sheets or films produced thereby
JP4646030B2 (ja) 2005-03-31 2011-03-09 株式会社 日立ディスプレイズ 液晶表示装置
DE102005017733A1 (de) 2005-04-15 2006-10-19 Basf Ag Löslichkeit von Cellulose in ionischen Flüssigkeiten unter Zugabe von Aminbase
DE102005017715A1 (de) 2005-04-15 2006-10-19 Basf Ag Lösungen von Cellulose in ionischen Flüssigkeiten
US7763715B2 (en) 2005-04-22 2010-07-27 The Procter & Gamble Company Extracting biopolymers from a biomass using ionic liquids
JP2006328298A (ja) 2005-05-30 2006-12-07 Konica Minolta Opto Inc 光学フィルム、偏光板及び液晶表示装置
AU2006266151B2 (en) 2005-06-29 2011-09-22 The University Of Alabama Ionic liquid reconstituted cellulose composites as solid support matrices
KR100843594B1 (ko) 2005-09-07 2008-07-03 주식회사 엘지화학 액상 산화 반응을 이용한 알데히드 화합물로부터의유기산의 제조 방법
WO2007029508A1 (ja) 2005-09-02 2007-03-15 Konica Minolta Medical & Graphic, Inc. 近赤外線吸収材料及びその製造方法
BRPI0616976A2 (pt) 2005-10-07 2009-11-24 Univ Alabama composições lìquidas iÈnicas multi-funcionais para superar polimorfismos e conferir propriedades a ingredientes ativos farmacêuticos, biológicos, nutricionais e energéticos
JP2007138141A (ja) 2005-10-21 2007-06-07 Fujifilm Corp セルロースアシレートの製造方法、セルロースアシレートフィルム、並びに、該フィルムを用いた偏光板、位相差フィルム、光学フィルムおよび液晶表示装置
WO2007049485A1 (ja) 2005-10-25 2007-05-03 Nisshinbo Industries, Inc. セルロース溶液の製造方法、セルロース溶液および再生セルロースの製造方法
CN100537603C (zh) 2005-11-01 2009-09-09 中国科学院过程工程研究所 利用植物纤维素生产醋酸纤维素酯的方法
DE102005055815A1 (de) 2005-11-21 2007-05-24 Basf Ag Verfahren zur Herstellung von ionischen Flüssigkeiten
CN1978433A (zh) 2005-12-09 2007-06-13 中国科学院兰州化学物理研究所 咪唑基双功能化的室温离子液体及其制备方法
EP1966284B1 (de) 2005-12-23 2013-04-17 Basf Se Lösungssystem auf der basis geschmolzener ionischer flüssigkeiten, dessen herstellung sowie verwendung zur herstellung regenerierter kohlenhydrate
CN100355960C (zh) 2005-12-26 2007-12-19 东华大学 一种离子液体为溶剂的纤维素纤维制备中溶剂的回收方法
JP4774303B2 (ja) 2006-01-26 2011-09-14 富士フイルム株式会社 セルロースアシレートフィルム、光学補償シート、偏光板、及び液晶表示装置
DE102006011075A1 (de) 2006-03-08 2007-09-13 Basf Ag Verfahren zum Abbau von Cellulose in Lösung
DE102006011077A1 (de) 2006-03-08 2007-09-13 Basf Ag Verfahren zum Abbau von Cellulose mit Nucleophilen
KR20080110608A (ko) 2006-03-08 2008-12-18 바스프 에스이 셀룰로오스의 분해 방법
US20070225191A1 (en) 2006-03-27 2007-09-27 The Procter & Gamble Company Methods for modifying bioplymers in ionic liquids
US7714124B2 (en) 2006-03-27 2010-05-11 The Procter & Gamble Company Methods for modifying cellulosic polymers in ionic liquids
JP5278720B2 (ja) 2006-03-27 2013-09-04 Ｎｌｔテクノロジー株式会社 液晶パネル、液晶表示装置及び端末装置
JP4887072B2 (ja) 2006-05-02 2012-02-29 富士フイルム株式会社 セルロース体フィルム、光学補償シート、偏光板、液晶表示装置
EP1860201A1 (en) 2006-05-25 2007-11-28 BP p.l.c. Conversion method
EP1911829A1 (en) 2006-10-10 2008-04-16 The Queen's University of Belfast Process for deacidifying crude oil
JP2007332292A (ja) 2006-06-15 2007-12-27 Fujifilm Corp セルロース体、セルロース体フィルム、光学補償シート、偏光板、液晶表示装置
US7976914B2 (en) 2006-06-16 2011-07-12 Fujifilm Corporaton Resin film, production method thereof, polarizing plate and liquid crystal display device
US20090281303A1 (en) 2006-06-23 2009-11-12 Basf Se Process for silylating cellulose
JP5112652B2 (ja) * 2006-06-28 2013-01-09 富士フイルム株式会社 セルロースアシレート組成物の製造方法およびセルロースアシレートフィルム
EP2041183A1 (de) 2006-07-07 2009-04-01 Basf Se Verfahren zur darstellung von celluloseacetalen
US7939681B2 (en) 2006-08-07 2011-05-10 Battelle Memorial Institute Methods for conversion of carbohydrates in ionic liquids to value-added chemicals
CN101522985B (zh) 2006-10-13 2013-01-16 巴斯夫欧洲公司 增溶聚合物的离子液体
GB0623473D0 (en) 2006-11-24 2007-01-03 Bristol Myers Squibb Co Dissolution and processing of cellulose
JP2008156623A (ja) 2006-11-30 2008-07-10 Sanyo Chem Ind Ltd アルキルエーテル化セルロースの製造方法
JP2009063983A (ja) 2006-12-21 2009-03-26 Fujifilm Corp 光学フィルム、及びそれを有する偏光板
BRPI0806908A2 (pt) 2007-01-23 2014-04-29 Basf Se Processos para a prepração de um produto de glicose a partir de um material lignocelulósico, e para a preparação de um produto de metabolismo microbiano, produto de glicose, e, produto de lignina
US20080188636A1 (en) 2007-02-06 2008-08-07 North Carolina State University Polymer derivatives and composites from the dissolution of lignocellulosics in ionic liquids
CN100572432C (zh) 2007-02-08 2009-12-23 中国纺织科学研究院 一种纤维素溶液及其制备方法
US9834516B2 (en) 2007-02-14 2017-12-05 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom
JP2010111707A (ja) 2007-02-22 2010-05-20 Nisshinbo Holdings Inc ポリマー処理剤およびドープ
US7674608B2 (en) 2007-02-23 2010-03-09 The University Of Toledo Saccharifying cellulose
JP2008248217A (ja) 2007-03-08 2008-10-16 Kri Inc 熱可塑性多糖ゲルおよびその製造方法ならびに多糖成形材料の製造方法
JP5563313B2 (ja) 2007-03-14 2014-07-30 ザ・ユニバーシティ・オブ・トレド バイオマス前処理
JP2010132558A (ja) 2007-03-16 2010-06-17 Nisshinbo Holdings Inc 多糖類の処理剤
JP5021537B2 (ja) 2007-03-28 2012-09-12 三洋化成工業株式会社 セルロースエーテルの製造方法
US20080241536A1 (en) 2007-03-29 2008-10-02 Weyerhaeuser Co. Method for processing cellulose in ionic liquids and fibers therefrom
WO2008119770A1 (de) 2007-03-30 2008-10-09 Basf Se Verfahren zur modifizierung der struktur eines cellulosematerials durch behandeln mit einer ionischen flüssigkeit
CN101289817B (zh) 2007-04-20 2010-07-28 中国科学院大连化学物理研究所 一种在离子液体中高效水解纤维素的方法
JP5339452B2 (ja) 2007-04-24 2013-11-13 国立大学法人東京農工大学 イオン液体およびこのイオン液体からなるポリマー処理剤
US8071813B2 (en) 2007-05-03 2011-12-06 Lawrence Livermore National Security, Llc Methods of using ionic liquids having a fluoride anion as solvents
JP5296334B2 (ja) 2007-06-08 2013-09-25 サンダイヤポリマー株式会社 吸水性ポリマーの製造方法及び吸収性樹脂粒子
KR101436170B1 (ko) 2007-06-26 2014-09-01 후지필름 가부시키가이샤 셀룰로오스아실레이트 조성물, 셀룰로오스아실레이트 필름,및 그 용도
CN101085838B (zh) 2007-07-03 2011-03-30 中国科学院化学研究所 一种连续制备纤维素/离子液体溶液的方法
DE102007035322B4 (de) 2007-07-25 2011-11-17 Friedrich-Schiller-Universität Jena Verfahren zur Herstellung wasserlöslicher, niedrig substituierter Cellulosesulfate
TW200912484A (en) 2007-07-30 2009-03-16 Fujifilm Corp Retardation film, polarizing plate, and liquid-crystal display device comprising it
US8349921B2 (en) 2007-08-24 2013-01-08 Eastman Chemical Company Mixed cellulose ester films having +C plate and −A plate optical properties
DE102007041416A1 (de) 2007-08-31 2009-03-05 Basf Se Destillation ionischer Flüssigkeiten
EP2033974A1 (en) 2007-09-06 2009-03-11 The Queens University of Belfast Conversion method
JP2009091542A (ja) 2007-09-21 2009-04-30 Daicel Chem Ind Ltd セルロース混合アシレートの製造方法、及び新規なセルロース混合アシレート
US20090084509A1 (en) 2007-09-28 2009-04-02 Weyerhaeuser Company Dissolution of Cellulose in Mixed Solvent Systems
CN104635291A (zh) 2007-10-11 2015-05-20 瑞尔D股份有限公司 弯曲光学滤光器
JP5291431B2 (ja) 2007-10-29 2013-09-18 富士フイルム株式会社 セルロースアシレートフィルム、反射防止フィルム、偏光板及び画像表示装置
EP2062922A1 (de) 2007-11-14 2009-05-27 Basf Se Verfahren zur Herstellung von regenerierten Biopolymeren und die danach erhältlichen regenerierten Erzeugnisse
CN101918368B (zh) 2007-12-14 2013-04-24 巴斯夫欧洲公司 改善离子液体的水解稳定性的方法
EP2072530A1 (de) 2007-12-21 2009-06-24 Dow Wolff Cellulosics GmbH Verfahren zur Herstellung aminogruppenhaltiger Cellulosederivate in ionischer Flüssigkeit
JP4740938B2 (ja) 2007-12-27 2011-08-03 ダイセル化学工業株式会社 ６位高アセチル化セルロースジアセテート及びその製造方法
CN101234197B (zh) 2008-01-29 2010-05-12 中国人民解放军第三军医大学 一种重组减毒鼠伤寒沙门氏菌载体疫苗及制备方法
US8999211B2 (en) 2008-02-11 2015-04-07 Basf Se Method for producing porous structures from synthetic polymers
US8354525B2 (en) 2008-02-13 2013-01-15 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom
EP2098539B1 (en) 2008-03-03 2017-05-10 SE Tylose GmbH & Co.KG Homogeneous synthesis of cellulose ethers in ionic liquids
WO2009116512A1 (ja) 2008-03-19 2009-09-24 住友化学株式会社 カルボニル化合物の製造方法
CN101285213A (zh) 2008-05-22 2008-10-15 高小山 一种精制棉纤维的制备方法
CN101284913A (zh) 2008-05-22 2008-10-15 高小山 以离子液体为溶剂的纤维素膜的制备方法
JP5222064B2 (ja) 2008-09-02 2013-06-26 富士フイルム株式会社 セルロースアシレート積層フィルム、その製造方法、偏光板および液晶表示装置
US8067488B2 (en) 2009-04-15 2011-11-29 Eastman Chemical Company Cellulose solutions comprising tetraalkylammonium alkylphosphate and products produced therefrom
US8254417B2 (en) * 2010-06-14 2012-08-28 Ipg Photonics Corporation Fiber laser system with controllably alignable optical components thereof
US20120003403A1 (en) 2010-07-02 2012-01-05 Eastman Chemical Company Multilayer cellulose ester film having reversed optical dispersion
JP5811651B2 (ja) 2010-09-14 2015-11-11 株式会社リコー 画像形成装置、画像形成装置の制御方法及びプログラム
US9096691B2 (en) 2011-04-13 2015-08-04 Eastman Chemical Company Cellulose ester optical films

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005089689A (ja) * 2003-09-19 2005-04-07 Fuji Photo Film Co Ltd セルロース組成物、セルロースフィルム、およびセルロースフィルム用の改質剤
WO2006013869A1 (en) * 2004-08-04 2006-02-09 Fujifilm Corporation Thermoplastic film and method of producing the same
JP2006232959A (ja) * 2005-02-24 2006-09-07 Fuji Photo Film Co Ltd セルロースアシレートフィルム、位相差板、偏光板、液晶表示装置およびセルロースアシレートフィルムの製造方法
EP1911792A1 (en) * 2005-05-24 2008-04-16 FUJIFILM Corporation Cellulose acylate film, and polarizing plate, optical compensation film and liquid crystal display using same
WO2007111339A1 (en) * 2006-03-20 2007-10-04 Fujifilm Corporation Cellulose acylate film and method for producing same, and retardation film, polarizer and liquid crystal display device comprising the film
WO2007144282A1 (de) * 2006-06-16 2007-12-21 Basf Se Verfahren zur acylierung von cellulose
WO2008000666A1 (de) * 2006-06-30 2008-01-03 Basf Se Verfahren zur acylierung von cellulose mit gezieltem durchschnittlichen polymerisationsgrad
WO2008100566A1 (en) * 2007-02-14 2008-08-21 Eastman Chemical Company Cellulose esters and their production in carboxylated ionic liquids
WO2008143765A2 (en) * 2007-05-14 2008-11-27 Eastman Chemical Company Cellulose esters with a high hydroxyl content and their use in liquid crystal displays
WO2009029220A1 (en) * 2007-08-24 2009-03-05 Eastman Chemical Company Mixed cellulose esters having low bifringence and films made therefrom
WO2009102305A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Treatment of cellulose esters
WO2009102307A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Production of cellulose esters in the presence of a cosolvent
WO2009102306A1 (en) * 2008-02-13 2009-08-20 Eastman Chemical Company Cellulose esters and their production in halogenated ionic liquids

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CAO ET AL: "Acetone-soluble cellulose acetates prepared by one-step homogeneous acetylation of cornhusk cellulose in an ionic liquid 1-allyl-3-methylimidazolium chloride (AmimCl)", CARBOHYDRATE POLYMERS, APPLIED SCIENCE PUBLISHERS, LTD. BARKING, GB, vol. 69, no. 4, 23 May 2007 (2007-05-23), pages 665 - 672, XP022093489, ISSN: 0144-8617 *
CAO Y ET AL: "Room temperature ionic liquids (RTILs): A new and versatile platform for cellulose processing and derivatization", CHEMICAL ENGINEERING JOURNAL, ELSEVIER SEQUOIA, LAUSANNE, CH, vol. 147, no. 1, 1 April 2009 (2009-04-01), pages 13 - 21, XP025924856, ISSN: 1385-8947, [retrieved on 20081118] *
WAGENKNECHT W: "REGIOSELECTIVE CELLULOSE DERIVATE DURCH MODIFIZIERUNG TECHNISCHER CELLULOSEACETATE. ÖREGIOSELECTIVE SUBSTITUTED CELLULOSE DERIVATIVES BY MODIFICATION OF COMMERCIAL CELLULOSE ACETATES", IPW INTERNATIONAL PAPER WORLD, DPW VERLAGSGESELLSCHAFT MBH, HEUSENSTAMM, DE, vol. 50, no. 12, 1 December 1996 (1996-12-01), pages 712 - 720, XP000637315, ISSN: 0031-1340 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2313438B1 (en) * 2008-08-13 2019-09-18 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom
EP3216806A1 (en) * 2009-04-15 2017-09-13 Eastman Chemical Company Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom
JP2013532311A (ja) * 2010-07-02 2013-08-15 イーストマン ケミカル カンパニー 逆光学分散を有する多層セルロースエステルフィルム
JP2017161916A (ja) * 2010-07-02 2017-09-14 イーストマン ケミカル カンパニー 逆光学分散を有する多層セルロースエステルフィルム
CN103459428A (zh) * 2011-03-30 2013-12-18 独立行政法人理化学研究所 纤维素衍生物的酯化物及其制造方法
EP2692738A4 (en) * 2011-03-30 2014-08-13 Riken ESTER COMPOUND OF CELLULOSIC DERIVATIVE AND METHOD FOR PREPARING THE SAME
CN103534274A (zh) * 2011-04-13 2014-01-22 伊士曼化工公司 纤维素酯光学膜
CN103717621A (zh) * 2011-04-13 2014-04-09 伊士曼化工公司 纤维素酯光学膜
CN103717621B (zh) * 2011-04-13 2016-10-12 伊士曼化工公司 纤维素酯光学膜
US9964667B2 (en) 2013-12-17 2018-05-08 Eastman Chemical Company Cellulose ester based quarter wave plates having normal wavelength dispersion

Also Published As

Publication number Publication date
JP2011530643A (ja) 2011-12-22
US9834516B2 (en) 2017-12-05
CN103923352B (zh) 2020-10-16
KR20110043757A (ko) 2011-04-27
US20100029927A1 (en) 2010-02-04
CN102124031B (zh) 2014-05-14
EP3239179A1 (en) 2017-11-01
CN102977216A (zh) 2013-03-20
CN102124031A (zh) 2011-07-13
EP3239179B1 (en) 2023-02-22
CN103923352A (zh) 2014-07-16
US20120101269A1 (en) 2012-04-26
EP2313439A1 (en) 2011-04-27

Similar Documents

Publication Publication Date Title
EP3239179B1 (en) Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom
US8354525B2 (en) Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom
US8153782B2 (en) Reformation of ionic liquids
US8188267B2 (en) Treatment of cellulose esters
US8273872B2 (en) Cellulose esters and their production in halogenated ionic liquids
US20120238742A1 (en) Production of cellulose esters in the presence of a cosolvent
US9777074B2 (en) Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom
US10174129B2 (en) Regioselectively substituted cellulose esters produced in a carboxylated ionic liquid process and products produced therefrom

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980131585.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09789131

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009789131

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2011522997

Country of ref document: JP

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 20117005787

Country of ref document: KR

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE