UY25040A1 - Derivados de 9-desoxo-9a-aza-9a-homoeritromicina a c-4' sustituidos - Google Patents
Derivados de 9-desoxo-9a-aza-9a-homoeritromicina a c-4' sustituidosInfo
- Publication number
- UY25040A1 UY25040A1 UY25040A UY25040A UY25040A1 UY 25040 A1 UY25040 A1 UY 25040A1 UY 25040 A UY25040 A UY 25040A UY 25040 A UY25040 A UY 25040A UY 25040 A1 UY25040 A1 UY 25040A1
- Authority
- UY
- Uruguay
- Prior art keywords
- infections
- formula
- compounds
- hydroxy
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 206010037075 Protozoal infections Diseases 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- HRKNNHYKWGYTEN-HOQMJRDDSA-N (2r,3s,4r,5r,8r,10r,11r,12s,13s,14r)-11-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)NC[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 HRKNNHYKWGYTEN-HOQMJRDDSA-N 0.000 abstract 1
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 1
- 206010018364 Glomerulonephritis Diseases 0.000 abstract 1
- 208000010315 Mastoiditis Diseases 0.000 abstract 1
- DBTDEFJAFBUGPP-UHFFFAOYSA-N Methanethial Chemical group S=C DBTDEFJAFBUGPP-UHFFFAOYSA-N 0.000 abstract 1
- 206010031252 Osteomyelitis Diseases 0.000 abstract 1
- 206010033078 Otitis media Diseases 0.000 abstract 1
- 201000007100 Pharyngitis Diseases 0.000 abstract 1
- 206010035664 Pneumonia Diseases 0.000 abstract 1
- 206010037294 Puerperal pyrexia Diseases 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 208000019802 Sexually transmitted disease Diseases 0.000 abstract 1
- 206010062255 Soft tissue infection Diseases 0.000 abstract 1
- 208000006374 Uterine Cervicitis Diseases 0.000 abstract 1
- 206010000269 abscess Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229960004099 azithromycin Drugs 0.000 abstract 1
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 206010008323 cervicitis Diseases 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
- 206010040872 skin infection Diseases 0.000 abstract 1
- 206010044008 tonsillitis Diseases 0.000 abstract 1
- 208000000143 urethritis Diseases 0.000 abstract 1
- 208000019206 urinary tract infection Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4934897P | 1997-06-11 | 1997-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY25040A1 true UY25040A1 (es) | 2000-09-29 |
Family
ID=21959336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY25040A UY25040A1 (es) | 1997-06-11 | 1998-06-11 | Derivados de 9-desoxo-9a-aza-9a-homoeritromicina a c-4' sustituidos |
Country Status (49)
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN1998000086A (es) * | 1997-06-11 | 1999-03-08 | Pfizer Prod Inc | Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos. |
| EP1779853A3 (en) * | 1997-09-10 | 2010-01-27 | Merial Ltd. | 9a-azalides as veterinary antimicrobial agents |
| AU731842B2 (en) * | 1997-09-10 | 2001-04-05 | Merck & Co., Inc. | 9a-azalides as veterinary antimicrobial agents |
| US6339063B1 (en) | 1997-09-10 | 2002-01-15 | Merck & Co., Inc. | 9a-azalides as veterinary antimicrobial agents |
| AP9801420A0 (en) * | 1998-01-02 | 1998-12-31 | Pfizer Prod Inc | Novel macrolides. |
| EP1437360A3 (en) * | 1998-08-19 | 2005-04-06 | Pfizer Products Inc. | C11 Carbamates of macrolide antibacterials |
| US6043227A (en) * | 1998-08-19 | 2000-03-28 | Pfizer Inc. | C11 carbamates of macrolide antibacterials |
| US6100240A (en) * | 1998-10-09 | 2000-08-08 | Pfizer Inc | Macrolide derivatives |
| CA2292359C (en) * | 1999-01-28 | 2004-09-28 | Pfizer Products Inc. | Novel azalides and methods of making same |
| PL353316A1 (en) * | 1999-05-18 | 2003-11-17 | Pfizer Products Inc. | Novel crystalline forms of a macrolide antibiotic |
| CZ20013733A3 (cs) * | 1999-05-24 | 2002-11-13 | Pfizer Products Inc. | Deriváty 13-methylerythromycinu |
| US6465437B1 (en) | 1999-06-30 | 2002-10-15 | Pfizer Inc. | Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition |
| US6764996B1 (en) | 1999-08-24 | 2004-07-20 | Abbott Laboratories | 9a-azalides with antibacterial activity |
| PT1206476E (pt) * | 1999-08-24 | 2006-05-31 | Abbott Lab | 9a-azalidos com actividade antibacteriana |
| US6608033B1 (en) * | 1999-08-27 | 2003-08-19 | Pfizer Inc. | Treatment or prevention of coccidiosis |
| ATE243703T1 (de) | 2000-01-27 | 2003-07-15 | Pfizer Prod Inc | Antibiotische azalid-zusammensetzungen |
| CN1227258C (zh) * | 2000-04-27 | 2005-11-16 | 辉瑞产品公司 | 氮杂大环内酯抗生素组合物在治疗或预防哺乳动物细菌或原生动物感染中的应用 |
| CN1297564C (zh) | 2001-04-27 | 2007-01-31 | 辉瑞产品公司 | 4″－取代－9－脱氧－9a－氮杂－9a－高红霉素A衍生物的制备方法 |
| WO2003011266A2 (en) * | 2001-08-01 | 2003-02-13 | Pfizer Products Inc. | Azalide antibiotic compositions |
| EP2772254A3 (en) | 2003-03-10 | 2015-03-11 | Optimer Pharmaceuticals, Inc. | Novel Antibacterial Agents |
| US7276487B2 (en) | 2003-09-23 | 2007-10-02 | Enanta Pharmaceuticals, Inc. | 9a, 11-3C-bicyclic 9a-azalide derivatives |
| KR100785601B1 (ko) * | 2003-11-21 | 2007-12-14 | 화이자 프로덕츠 인크. | 백신 아쥬반트로서의 항생제의 용도 |
| EA011158B1 (ru) * | 2004-03-16 | 2009-02-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Замещённые глюкопиранозилом бензольные производные, содержащие эти соединения лекарственные средства, их применение и способ их получения |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| US7402568B2 (en) | 2004-09-29 | 2008-07-22 | Enanta Pharmaceuticals, Inc. | Bicyclic 9a-azalide derivatives |
| US7767797B1 (en) * | 2004-09-30 | 2010-08-03 | Synovo Gmbh | Macrocyclic compounds and methods of use thereof |
| US7271155B2 (en) | 2005-01-07 | 2007-09-18 | Enanta Pharmaceuticals, Inc. | 9A, 11-2C-bicyclic 9a-azalide derivatives |
| EP1841437B1 (en) * | 2005-01-14 | 2009-04-29 | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. | 9a-carbamoyl and thiocarbamoyl azalides with antimalarial activity |
| JP5698979B2 (ja) * | 2007-10-25 | 2015-04-08 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライド系抗菌剤の調製プロセス |
| EP2358379B1 (en) | 2008-10-24 | 2015-12-16 | Cempra Pharmaceuticals, Inc. | Biodefenses using triazole-containing macrolides |
| US9937194B1 (en) * | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| EP2475253B1 (en) | 2009-09-10 | 2016-10-26 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and mac diseases |
| AU2011232627B2 (en) | 2010-03-22 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Crystalline forms of a macrolide, and uses therefor |
| RU2608390C2 (ru) | 2010-05-20 | 2017-01-18 | Семпра Фармасьютикалз, Инк. | Способы получения макролидов и кетолидов, и промежуточных соединений для их получения |
| WO2012034058A1 (en) | 2010-09-10 | 2012-03-15 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
| ES2532455T3 (es) * | 2010-09-20 | 2015-03-27 | Novartis Tiergesundheit Ag | Nuevo procedimiento de preparación de 9-desoxo-9a-aza-9a-homoeritromicina modificada en el C-4'' del anillo de cladinosa por un grupo epóxido |
| AU2011313862A1 (en) * | 2010-10-10 | 2013-05-30 | Synovo Gmbh | Anti-inflammatory macrolides |
| CN102993250B (zh) * | 2011-07-06 | 2016-02-10 | 洛阳惠中兽药有限公司 | C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物 |
| CN102260306B (zh) * | 2011-07-22 | 2012-07-18 | 山东鲁抗舍里乐药业有限公司 | 一种制备泰拉霉素的方法 |
| WO2013013834A1 (en) | 2011-07-27 | 2013-01-31 | Farma Grs, D.O.O. | New crystalline forms of tulathromycin |
| JP6208742B2 (ja) | 2012-03-27 | 2017-10-04 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライド抗生物質を投与するための非経口製剤 |
| CN102786569B (zh) * | 2012-09-07 | 2016-12-07 | 安徽中升药业有限公司 | 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法 |
| US9861616B2 (en) | 2013-03-14 | 2018-01-09 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| US9751908B2 (en) | 2013-03-15 | 2017-09-05 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| SI3027634T1 (sl) * | 2013-07-31 | 2018-10-30 | Farma Grs, D.O.O. | Proces za pripravo tulatromicina |
| CN103497227B (zh) * | 2013-09-13 | 2015-09-30 | 青岛科技大学 | 一种泰拉菌素中间体的制备方法 |
| CN104725446B (zh) * | 2015-03-26 | 2017-10-27 | 宁夏泰瑞制药股份有限公司 | 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法 |
| CN104861018A (zh) * | 2015-06-17 | 2015-08-26 | 瑞普（天津）生物药业有限公司 | 一种泰拉菌素的制备方法 |
| CN105646617A (zh) * | 2016-01-21 | 2016-06-08 | 杭州海尔希畜牧科技有限公司 | 一种制备泰拉霉素的方法 |
| FR3048612B1 (fr) * | 2016-03-14 | 2020-10-02 | Septeos | Tulathromycine potentialisee |
| CN106046077B (zh) * | 2016-08-04 | 2019-07-26 | 湖北美天生物科技股份有限公司 | 一种泰拉霉素a的合成方法 |
| CN108003207B (zh) | 2017-12-19 | 2019-05-10 | 海门慧聚药业有限公司 | 制备泰拉霉素的方法 |
| CN111087433B (zh) * | 2018-10-23 | 2023-03-21 | 湖北美天生物科技股份有限公司 | 一种泰拉霉素中间体的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI8110592A8 (en) * | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
| US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US4512982A (en) * | 1984-04-13 | 1985-04-23 | Pfizer Inc. | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method |
| CA2064634C (en) * | 1991-04-04 | 1998-08-04 | James V. Heck | 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions |
| US5226958A (en) * | 1991-04-11 | 1993-07-13 | Pacemark, Inc. | Sealant for pneumatic inner tubes and tubeless tires |
| EP0549040A1 (en) * | 1991-12-20 | 1993-06-30 | Merck & Co. Inc. | Methods of making 4" derivatives of 9-deoxo-8a-aza-8a-alkyl-8a-homoerythromycin A |
| US5441939A (en) * | 1994-03-04 | 1995-08-15 | Pfizer Inc. | 3"-desmethoxy derivatives of erythromycin and azithromycin |
| HN1998000086A (es) * | 1997-06-11 | 1999-03-08 | Pfizer Prod Inc | Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos. |
| UA70972C2 (uk) | 1998-11-20 | 2004-11-15 | Пфайзер Продактс Інк. | 13-членні азаліди і їх застосування як антибіотиків |
-
1998
- 1998-05-03 HN HN1998000086A patent/HN1998000086A/es unknown
- 1998-05-27 PA PA19988452201A patent/PA8452201A1/es unknown
- 1998-05-29 PL PL337505A patent/PL191601B1/pl unknown
- 1998-05-29 CA CA002293823A patent/CA2293823C/en not_active Expired - Lifetime
- 1998-05-29 IL IL13280998A patent/IL132809A0/xx not_active IP Right Cessation
- 1998-05-29 JP JP50193599A patent/JP3315704B2/ja not_active Expired - Lifetime
- 1998-05-29 CN CNB988059223A patent/CN1172947C/zh not_active Expired - Lifetime
- 1998-05-29 BR BRPI9810519A patent/BRPI9810519B8/pt not_active IP Right Cessation
- 1998-05-29 DE DE122004000018C patent/DE122004000018I2/de active Active
- 1998-05-29 AT AT98920693T patent/ATE251173T1/de active
- 1998-05-29 EP EP98920693A patent/EP0988310B9/en not_active Expired - Lifetime
- 1998-05-29 AU AU73475/98A patent/AU749816B2/en not_active Expired
- 1998-05-29 UA UA99126736A patent/UA67744C2/uk unknown
- 1998-05-29 ES ES98920693T patent/ES2205487T3/es not_active Expired - Lifetime
- 1998-05-29 SI SI9830572T patent/SI0988310T1/xx unknown
- 1998-05-29 NZ NZ500660A patent/NZ500660A/en not_active IP Right Cessation
- 1998-05-29 DK DK98920693T patent/DK0988310T3/da active
- 1998-05-29 ID IDW991569A patent/ID22992A/id unknown
- 1998-05-29 CN CN2006100513455A patent/CN1793155B/zh not_active Expired - Lifetime
- 1998-05-29 EA EA199901015A patent/EA002441B1/ru not_active IP Right Cessation
- 1998-05-29 CN CNB2004100491122A patent/CN1243766C/zh not_active Expired - Lifetime
- 1998-05-29 KR KR10-1999-7011642A patent/KR100396168B1/ko not_active Expired - Lifetime
- 1998-05-29 CZ CZ0442199A patent/CZ298556B6/cs not_active IP Right Cessation
- 1998-05-29 US US09/424,104 patent/US6420536B1/en not_active Expired - Lifetime
- 1998-05-29 WO PCT/IB1998/000839 patent/WO1998056802A1/en not_active Ceased
- 1998-05-29 CN CN200910145318A patent/CN101691390A/zh active Pending
- 1998-05-29 DE DE69818665T patent/DE69818665T2/de not_active Expired - Lifetime
- 1998-05-29 ME MEP-1999-586A patent/ME00876B/me unknown
- 1998-05-29 HU HU0002209A patent/HU228005B1/hu active Protection Beyond IP Right Term
- 1998-05-29 RS YUP-586/99A patent/RS49675B/sr unknown
- 1998-05-29 PT PT98920693T patent/PT988310E/pt unknown
- 1998-05-29 NZ NZ514871A patent/NZ514871A/en not_active IP Right Cessation
- 1998-05-29 SK SK1683-99A patent/SK284171B6/sk not_active IP Right Cessation
- 1998-06-04 AP APAP/P/1998/001255A patent/AP1231A/en active
- 1998-06-08 PE PE1998000471A patent/PE79699A1/es not_active Application Discontinuation
- 1998-06-09 AR ARP980102706A patent/AR013086A1/es active IP Right Grant
- 1998-06-09 EG EG64098A patent/EG24081A/xx active
- 1998-06-09 MY MYPI98002575A patent/MY123354A/en unknown
- 1998-06-10 CO CO98033232A patent/CO4950611A1/es unknown
- 1998-06-10 DZ DZ980124A patent/DZ2514A1/xx active
- 1998-06-10 ZA ZA9805017A patent/ZA985017B/xx unknown
- 1998-06-10 MA MA25107A patent/MA24564A1/fr unknown
- 1998-06-10 TN TNTNSN98082A patent/TNSN98082A1/fr unknown
- 1998-06-10 GT GT199800077A patent/GT199800077A/es unknown
- 1998-06-11 HR HR980314A patent/HRP980314B1/xx not_active IP Right Cessation
- 1998-06-11 UY UY25040A patent/UY25040A1/es not_active IP Right Cessation
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1999
- 1999-02-26 TW TW087109077A patent/TW472060B/zh not_active IP Right Cessation
- 1999-11-16 IS IS5252A patent/IS1998B/is unknown
- 1999-12-03 BG BG103945A patent/BG64391B1/bg unknown
- 1999-12-03 OA OA9900268A patent/OA11224A/en unknown
- 1999-12-10 NO NO996106A patent/NO316911B1/no not_active IP Right Cessation
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2001
- 2001-11-21 US US09/989,936 patent/US20020061858A1/en not_active Abandoned
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2002
- 2002-03-13 JP JP2002068432A patent/JP2002316933A/ja active Pending
- 2002-10-18 US US10/273,879 patent/US6777393B2/en not_active Expired - Lifetime
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2004
- 2004-03-26 US US10/810,922 patent/US6936592B2/en not_active Expired - Lifetime
- 2004-05-04 FR FR04C0013C patent/FR04C0013I2/fr active Active
- 2004-05-05 LU LU91076C patent/LU91076I9/fr unknown
- 2004-05-10 NL NL300150C patent/NL300150I2/nl unknown
-
2012
- 2012-11-26 HU HUS1200028C patent/HUS1200028I1/hu unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| VENC | Patent expired |
Effective date: 20180611 |