UA63993C2 - Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул - Google Patents

Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул

Info

Publication number
UA63993C2
UA63993C2 UA2000105783A UA2000105783A UA63993C2 UA 63993 C2 UA63993 C2 UA 63993C2 UA 2000105783 A UA2000105783 A UA 2000105783A UA 2000105783 A UA2000105783 A UA 2000105783A UA 63993 C2 UA63993 C2 UA 63993C2
Authority
UA
Ukraine
Prior art keywords
dosage forms
flash
oral dosage
granules
variants
Prior art date
Application number
UA2000105783A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Х. Котарі Санджеєв
С. Десаі Дів'якант
Original Assignee
Брістол-Майерс Сквібб Компані
Бристол-Майерс Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24186805&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA63993(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Брістол-Майерс Сквібб Компані, Бристол-Майерс Сквибб Компани filed Critical Брістол-Майерс Сквібб Компані
Publication of UA63993C2 publication Critical patent/UA63993C2/uk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UA2000105783A 2000-04-12 2000-10-12 Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул UA63993C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54794800A 2000-04-12 2000-04-12

Publications (1)

Publication Number Publication Date
UA63993C2 true UA63993C2 (uk) 2004-02-16

Family

ID=24186805

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2000105783A UA63993C2 (uk) 2000-04-12 2000-10-12 Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул

Country Status (43)

Country Link
US (3) US20100016448A1 (OSRAM)
EP (2) EP1145711B1 (OSRAM)
JP (1) JP3773763B2 (OSRAM)
KR (1) KR100477293B1 (OSRAM)
CN (1) CN100353933C (OSRAM)
AR (1) AR024384A1 (OSRAM)
AT (1) ATE328584T1 (OSRAM)
AU (1) AU752214B2 (OSRAM)
BG (1) BG65007B1 (OSRAM)
BR (1) BR0003158A (OSRAM)
CA (1) CA2311734C (OSRAM)
CO (1) CO5190672A1 (OSRAM)
CY (1) CY1105170T1 (OSRAM)
CZ (1) CZ299145B6 (OSRAM)
DE (1) DE60028536T2 (OSRAM)
DK (1) DK1145711T3 (OSRAM)
EE (1) EE04331B1 (OSRAM)
EG (1) EG23943A (OSRAM)
ES (1) ES2265836T3 (OSRAM)
GE (1) GEP20022851B (OSRAM)
HK (1) HK1039572B (OSRAM)
HU (1) HU228864B1 (OSRAM)
ID (1) ID29837A (OSRAM)
IL (1) IL136901A (OSRAM)
IN (1) IN188856B (OSRAM)
LT (1) LT4896B (OSRAM)
LV (1) LV12731B (OSRAM)
MY (1) MY125766A (OSRAM)
NO (1) NO330270B1 (OSRAM)
NZ (1) NZ505302A (OSRAM)
PE (1) PE20010298A1 (OSRAM)
PL (1) PL200409B1 (OSRAM)
PT (1) PT1145711E (OSRAM)
RO (1) RO118563B1 (OSRAM)
RU (1) RU2201216C2 (OSRAM)
SG (2) SG117445A1 (OSRAM)
SI (1) SI20511B (OSRAM)
SK (1) SK286368B6 (OSRAM)
TR (1) TR200001810A2 (OSRAM)
TW (1) TWI262799B (OSRAM)
UA (1) UA63993C2 (OSRAM)
UY (1) UY26306A1 (OSRAM)
ZA (1) ZA200003121B (OSRAM)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19820801A1 (de) * 1998-05-09 1999-11-25 Gruenenthal Gmbh Orale Arzneiformen mit reproduzierbarer Wirkstofffreisetzung von Gatifloxacin oder pharmazeutisch verwendbaren Salzen oder Hydraten
CA2311734C (en) 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
US20020076437A1 (en) 2000-04-12 2002-06-20 Sanjeev Kothari Flashmelt oral dosage formulation
US7053092B2 (en) 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
US7067148B2 (en) 2001-02-15 2006-06-27 King Pharmaceutical Research & Development, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
MY129350A (en) * 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
PE20030445A1 (es) * 2001-09-25 2003-07-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
EP1441698B1 (en) * 2001-10-09 2018-05-02 Otsuka Pharmaceutical Co., Ltd. Flashmelt oral dosage formulation
US6610266B2 (en) 2001-11-28 2003-08-26 Michael C. Withiam Calcium metasilicates and methods for making
EP1453826A1 (en) * 2001-12-10 2004-09-08 Dr. Reddy's Laboratories Ltd. Amorphous form of 2-n-butyl-3-[[2-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4'] non-1-en-4-one
JP4551092B2 (ja) * 2002-03-06 2010-09-22 協和発酵キリン株式会社 口腔内速崩壊性錠剤
WO2003086343A2 (en) * 2002-04-05 2003-10-23 Cadila Healthcare Limited Fast disintegrating oral dosage forms
TWI275392B (en) * 2002-04-08 2007-03-11 Bristol Myers Squibb Co Low dose liquid entecavir formulations and use
BR0313602A (pt) 2002-08-20 2005-06-21 Bristol Myers Squibb Co Método e formulação de complexo de aripiprazol
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
MXPA05005971A (es) * 2002-12-11 2005-12-05 Squibb Bristol Myers Co Proceso para preparar le agente antiviral [1s-(1alfa, 3 alfa, 4 beta)]-2- amino-1, 9-dihidro- 9-[4-hidroxi- 3-hidroximetil)- 2-metilenciclopentil] -6h- purin-6 -ona.
US8349361B2 (en) 2003-10-15 2013-01-08 Fuji Chemical Industry Co., Ltd. Composition for rapid disintegrating tablet in oral cavity
JP3841804B2 (ja) * 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
RU2253451C1 (ru) * 2004-03-15 2005-06-10 Общество с ограниченной ответственностью "ЮНАЛ" Антиаллергическое средство
DE602005025755D1 (de) 2004-06-04 2011-02-17 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
WO2005123040A1 (ja) * 2004-06-22 2005-12-29 Shionogi & Co., Ltd. 口腔内速崩壊錠
US20090062404A1 (en) * 2005-03-24 2009-03-05 Daiichi Sankyo Company, Limited Pharmaceutical composition
TWI383809B (zh) * 2005-06-29 2013-02-01 Otsuka Pharma Co Ltd 含有西洛他唑(cilostazol)之口腔崩解粉末
DE602006006536D1 (de) * 2006-01-05 2009-06-10 Teva Pharma Trockene Aripiprazolformulierungen
WO2007081366A1 (en) 2006-01-05 2007-07-19 Teva Pharmaceutical Industries Ltd. Wet granulation pharmaceutical compositions of aripiprazole
PL1806130T3 (pl) * 2006-01-09 2010-08-31 Krka D D Novo Mesto Kompozycja farmaceutyczna w postaci stałej zawierająca irbesartan
AU2007232098A1 (en) 2006-03-31 2007-10-11 Rubicon Research Private Limited Directly compressible composite for orally disintegrating tablets
ES2779826T3 (es) 2007-02-23 2020-08-20 Gilead Sciences Inc Moduladores de propiedades farmacocinéticas de agentes terapéuticos
ATE533477T1 (de) * 2007-04-17 2011-12-15 Ratiopharm Gmbh Pharmazeutische zusammensetzungen enthaltend irbesartan
ES2745438T3 (es) * 2007-05-08 2020-03-02 Hercules Llc Formulación robusta de comprimidos de desintegración rápida
CN101322709B (zh) * 2007-06-12 2011-03-02 成都康弘药业集团股份有限公司 一种含有阿立哌唑的药物组合物及其制备方法
NZ588978A (en) 2008-05-02 2013-01-25 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
JP5296456B2 (ja) * 2008-08-26 2013-09-25 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
EP2409688A4 (en) * 2009-03-16 2013-06-05 Nipro Corp COMPRESSED ORAL DISCLAIMER
WO2010146551A2 (en) * 2009-06-16 2010-12-23 Ranbaxy Laboratories Limited Orally disintegrating compositions comprising antihypertensive agents
EP2477609A1 (en) 2009-09-15 2012-07-25 Ratiopharm GmbH Orally disintegrating pharmaceutical dosage form containing aripiprazole
TR201000689A1 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Sefprozil içeren katı dozaj formlar.
CN103284968B (zh) * 2010-04-13 2015-11-18 齐鲁制药有限公司 一种阿立哌唑组合物微晶的口腔崩解片及其制备方法
EP2384742A1 (en) 2010-05-03 2011-11-09 The Jordanian Pharmaceutical Manufacturing Co. Pharmaceutical excipient, method for its preparation and use thereof
DE102010019416A1 (de) * 2010-05-04 2011-11-10 Stada Arzneimittel Ag Schmelztablette, umfassend ein Triptan oder ein atypisches Neuroleptikum
HU1000278D0 (en) 2010-05-28 2010-07-28 Egis Gyogyszergyar Nyilvanosan Novel pharmaceutical use uf silicic acid
JP2012121850A (ja) * 2010-12-09 2012-06-28 Otsuka Pharmaceut Co Ltd アリピプラゾールの経口速溶性組成物
SI2685979T1 (sl) 2011-03-18 2017-04-26 Alkermes Pharma Ireland Limited Injekcijski farmacevtski sestavki, ki obsegajo vodotopni antipsihotik, sorbitan lavrat in polisorbat 20
MX2013010616A (es) * 2011-03-21 2014-08-18 Coloright Ltd Sistema de coloracion confeccionados.
US9241876B2 (en) * 2011-06-27 2016-01-26 Shanghai Zhongxi Pharmaceutical Corporation Aripiprazole medicament formulation and preparation method therefor
CN102846564B (zh) * 2011-06-28 2013-10-09 南京亿华药业有限公司 一种头孢丙烯片及其制法
CN102357086A (zh) * 2011-11-01 2012-02-22 上海理工大学 一种头孢丙烯口腔崩解片
MX2014007933A (es) * 2011-12-26 2014-07-30 Novartis Ag Comprimidos y agentes recubiertos en seco.
EP2827866B1 (en) 2012-03-19 2023-05-03 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising benzyl alcohol
WO2013142198A1 (en) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Pharmaaceutical compositions comprising fatty acid esters
ES2764383T3 (es) 2012-03-19 2020-06-03 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden ésteres de glicerol
WO2013175508A2 (en) 2012-05-24 2013-11-28 Medreich Limited Stable pharmaceutical composition of aripiprazole
CA2779052A1 (en) * 2012-05-31 2013-11-30 Pharmascience Inc. Pharmaceutical composition of entecavir and process of manufacturing
KR101571670B1 (ko) 2012-08-08 2015-11-25 주식회사 씨엠지제약 아리피프라졸을 포함하는 경구용 속용 필름 제제
US20150224086A1 (en) * 2012-08-23 2015-08-13 Hetero Research Foundation Pharmaceutical Formulations of Rufinamide
CA2885196C (en) 2012-09-19 2021-06-22 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
CN102885790B (zh) * 2012-09-20 2013-12-25 中国人民解放军第三〇二医院 恩替卡韦分散片及其制备方法
WO2014178334A1 (en) 2013-04-30 2014-11-06 Otsuka Pharmaceutical Co., Ltd. Oral solid preparation comprising aripiprazole and method for producing oral solid preparation comprising aripiprazole
JP5714652B2 (ja) * 2013-06-13 2015-05-07 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
WO2015067313A1 (en) 2013-11-07 2015-05-14 Synthon B.V. Orodispersible pharmaceutical compositions comprising aripiprazole
MX376057B (es) 2014-03-20 2025-03-07 Alkermes Pharma Ireland Ltd Formulaciones de aripiprazol que tienen mayores velocidades de inyeccion.
JP5978335B2 (ja) * 2015-03-11 2016-08-24 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
KR20160139704A (ko) 2015-05-28 2016-12-07 주식회사 씨엠지제약 아리피프라졸을 포함하는 경구용 속용 필름 제제, 및 이의 제조방법
JP2015172084A (ja) * 2015-07-06 2015-10-01 大塚製薬株式会社 アリピプラゾールの経口速溶性組成物
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
TR201617675A2 (tr) 2016-12-02 2018-06-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Ari̇pi̇prazole monohi̇drat formülasyonlarinin ağizda dağilan tablet formu
JP6572257B2 (ja) * 2017-05-16 2019-09-04 大塚製薬株式会社 アリピプラゾールの経口速溶性組成物
JP2017141299A (ja) * 2017-05-24 2017-08-17 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
US11273158B2 (en) 2018-03-05 2022-03-15 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
JP2018168185A (ja) * 2018-07-05 2018-11-01 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
JP2019203031A (ja) * 2019-09-06 2019-11-28 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
RU2732291C1 (ru) * 2020-02-13 2020-09-15 Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") Лекарственный препарат на основе травы алтея лекарственного для лечения простудных и острых респираторных заболеваний
GB2617603B (en) * 2022-04-13 2025-06-04 Univ Brunel Compositions for preventing and treating infection
CN115227661B (zh) * 2022-09-22 2022-12-13 北京惠之衡生物科技有限公司 一种利格列汀片及其制备方法

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1912354B2 (de) * 1969-03-12 1972-04-13 Reimbold & Strick, 5000 Köln-Kalk Synthetisches kristallines calciumsilikat und verfahren zu seiner herstellung
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
FR2234244B1 (OSRAM) * 1973-06-20 1978-02-17 Rech Geolog Miniere
DE2556561C2 (de) 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung von porösen Tabletten
DE2845326C2 (de) * 1978-10-18 1985-05-23 Beiersdorf Ag, 2000 Hamburg Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
DE2849494A1 (de) 1978-11-15 1980-05-29 Voss Gunter M Verfahren zur herstellung von arzneimittel-formlingen
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
JPS59106473A (ja) * 1982-12-10 1984-06-20 Nippon Shinyaku Co Ltd トリアジン誘導体
ZA87279B (en) 1986-01-17 1987-09-30 Chugai Pharmaceutical Co Ltd Method for production of stable nicorandil preparation
KR880701098A (ko) * 1986-04-01 1988-07-25 로버어트 에이 아미테이지 메틸프레드니솔론/소디움 카르복시메틸 전분 정제 조성물
SE8601624D0 (sv) 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
US5032552A (en) * 1988-07-04 1991-07-16 Tdk Corporation Biomedical material
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
US4906478A (en) * 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
HU203041B (en) 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH06271744A (ja) * 1993-03-22 1994-09-27 Mizusawa Ind Chem Ltd ポリアセタール系樹脂用帯電防止剤
US5393472A (en) * 1993-06-30 1995-02-28 Shaw; John D. Method of producing wollastonite & ceramic bodies containing wollastonite
IL110376A (en) * 1993-08-02 1998-08-16 Bristol Myers Squibb Co Pharmaceutical compositions containing ifetroban salts and methods for the preparation thereof
WO1995003785A1 (en) * 1993-08-03 1995-02-09 Warner-Lambert Company Pleasant tasting effervescent cold/allergy medications
US5622719A (en) * 1993-09-10 1997-04-22 Fuisz Technologies Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5895664A (en) * 1993-09-10 1999-04-20 Fuisz Technologies Ltd. Process for forming quickly dispersing comestible unit and product therefrom
WO1996004914A1 (fr) * 1994-08-08 1996-02-22 Nippon Shinyaku Co., Ltd. Derive de triazine et medicament
TW318841B (OSRAM) * 1995-02-17 1997-11-01 Takeda Pharm Industry Co Ltd
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
TW442301B (en) * 1995-06-07 2001-06-23 Sanofi Synthelabo Pharmaceutical compositions containing irbesartan
EP0861216B1 (en) * 1995-11-17 2000-05-10 Vrije Universiteit Brussel Inorganic resin compositions, their preparation and use thereof
TW430561B (en) * 1995-12-20 2001-04-21 Gea Farmaceutisk Fabrik As Rapid release tablet composition comprising tolfenamic acid or a pharmaceutically acceptable salt thereof as active ingredient and a method of preparing such tablet
DE69712332T2 (de) * 1996-02-29 2002-10-02 Fujisawa Pharmaceutical Co., Ltd. Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
DE69738829D1 (de) * 1996-07-12 2008-08-21 Daiichi Seiyaku Co Schnell zerfallende, druckgeformte Materialien sowie Prozess zu deren Herstellung
AU3726597A (en) * 1996-07-23 1998-02-10 Fmc Corporation Disintegrant composition for dispersible solids
JPH10114655A (ja) 1996-10-09 1998-05-06 Kyowa Hakko Kogyo Co Ltd 固形製剤
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
AUPO446397A0 (en) 1997-01-07 1997-01-30 Rees Equipment Pty Ltd Agricultural equipment direction control
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
TW527195B (en) * 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11152220A (ja) * 1997-11-19 1999-06-08 Daiichi Yakuhin Kogyo Kk 脂溶性薬物を含有した丸剤の製造方法
IL136831A0 (en) * 1997-12-19 2001-06-14 Smithkline Beecham Corp Process for manufacturing bite-dispersion tablets
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
DE69901938T3 (de) 1998-03-06 2012-08-02 Aptalis Pharma S.R.L. Schnell zerfallende tablette
JP4027535B2 (ja) 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末
PE20000559A1 (es) * 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz
JP2000119014A (ja) 1998-08-12 2000-04-25 Fuji Chem Ind Co Ltd 無晶形ケイ酸アルミン酸カルシウム複合酸化物及びその製造方法並びに制酸剤
JP2000086537A (ja) 1998-09-11 2000-03-28 Fuji Chem Ind Co Ltd 無機化合物糖類組成物、賦形剤、速崩壊性圧縮成型物及びその製造方法
US6133378A (en) * 1998-11-20 2000-10-17 Bridgestone/Firestone, Inc. EPDM-based roofing shingle compositions
GB9914936D0 (en) 1999-06-26 1999-08-25 Cerestar Holding Bv Directly compressible starch as enhancer of properties of excipients when used as binder and disintegrant for compression tablets
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
US20020076437A1 (en) * 2000-04-12 2002-06-20 Sanjeev Kothari Flashmelt oral dosage formulation
CN100381847C (zh) 2001-06-29 2008-04-16 美莎诺普有限公司 高精度凹型多光纤连接器
TWI324074B (en) * 2001-10-09 2010-05-01 Bristol Myers Squibb Co Flashmelt oral dosage formulation
US6610266B2 (en) * 2001-11-28 2003-08-26 Michael C. Withiam Calcium metasilicates and methods for making

Also Published As

Publication number Publication date
HU228864B1 (en) 2013-06-28
HUP0002316A3 (en) 2008-04-28
EG23943A (en) 2008-01-22
ZA200003121B (en) 2001-12-21
IN188856B (OSRAM) 2002-11-16
RU2201216C2 (ru) 2003-03-27
SI20511B (sl) 2008-08-31
NZ505302A (en) 2001-12-21
EE04331B1 (et) 2004-08-16
DE60028536D1 (de) 2006-07-20
DK1145711T3 (da) 2006-10-02
CY1105170T1 (el) 2010-03-03
DE60028536T2 (de) 2007-05-16
HUP0002316A2 (hu) 2002-11-28
CN1317309A (zh) 2001-10-17
JP2001302499A (ja) 2001-10-31
GEP20022851B (en) 2002-12-25
US20110217342A1 (en) 2011-09-08
BR0003158A (pt) 2001-12-18
SG117445A1 (en) 2005-12-29
SG108230A1 (en) 2005-01-28
CA2311734A1 (en) 2001-10-12
KR20010096450A (ko) 2001-11-07
TWI262799B (en) 2006-10-01
CN100353933C (zh) 2007-12-12
CZ20002391A3 (cs) 2001-11-14
US20100016448A1 (en) 2010-01-21
RO118563B1 (ro) 2003-07-30
PL200409B1 (pl) 2009-01-30
TR200001810A3 (tr) 2001-11-21
HU0002316D0 (en) 2000-08-28
IL136901A (en) 2008-03-20
US9358207B2 (en) 2016-06-07
CZ299145B6 (cs) 2008-04-30
LV12731B (en) 2002-03-20
MY125766A (en) 2006-08-30
SK9732000A3 (en) 2001-11-06
EP1145711A1 (en) 2001-10-17
TR200001810A2 (tr) 2001-11-21
UY26306A1 (es) 2001-12-28
CO5190672A1 (es) 2002-08-29
BG104693A (en) 2002-02-28
LT2000064A (en) 2001-10-25
CA2311734C (en) 2011-03-08
PL341466A1 (en) 2001-10-22
HK1039572A1 (en) 2002-05-03
LT4896B (lt) 2002-02-25
AU752214B2 (en) 2002-09-12
JP3773763B2 (ja) 2006-05-10
AU4373300A (en) 2001-10-18
PE20010298A1 (es) 2001-05-20
IL136901A0 (en) 2001-06-14
EP1145711B1 (en) 2006-06-07
NO20003196L (no) 2001-10-15
LV12731A (en) 2001-10-20
BG65007B1 (bg) 2006-12-29
SI20511A (sl) 2001-10-31
NO330270B1 (no) 2011-03-14
US20130296337A1 (en) 2013-11-07
KR100477293B1 (ko) 2005-03-17
EE200000497A (et) 2001-12-17
US8518421B2 (en) 2013-08-27
PT1145711E (pt) 2006-11-30
SK286368B6 (sk) 2008-08-05
AR024384A1 (es) 2002-10-02
NO20003196D0 (no) 2000-06-20
HK1039572B (en) 2007-01-12
EP1566174A3 (en) 2007-04-04
ES2265836T3 (es) 2007-03-01
EP1566174A2 (en) 2005-08-24
ID29837A (id) 2001-10-18
ATE328584T1 (de) 2006-06-15

Similar Documents

Publication Publication Date Title
UA63993C2 (uk) Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул
MY127350A (en) Flash-melt oral dose formulations
AU1232600A (en) Dosage forms containing taste masked active agents
CA2232450A1 (en) Oral pharmaceutical composition containing antimicrobial actives and sustained release pantoprazole
IS1694B (is) Lyfjablanda til að gefa dýrum um munn sem inniheldur prótonupumpublokkara
UA84266C2 (uk) Дозована лікарська форма у вигляді таблетки або пелети для перорального введення, яка містить інгібітор pde 4 та полівінілпіролідон, способи її одержання та застосування
HUP0302131A2 (hu) Gyógyászati tramadolsók, ezeket tartalmazó gyógyszerkészítmények
BR0103033A (pt) Partìculas farmacêuticas de sabor mascarado
MXPA04003346A (es) Formulacion de dosis oral de disolucion instantanea.
AU2002231654A1 (en) Pharmaceutical paste comprising an acid-labile active ingredient
CA2622805A1 (en) Compressed tablets comprising valsartan
PT1411921E (pt) Composições farmacêuticas contendo terbinafina e suas utilizações
IL150528A0 (en) Ibuprofen containing active agent preparation
MXPA06000332A (es) Nueva composicion farmaceutica solida que comprende amisulprida.
WO2003061557A3 (en) Levothyroxine pharmaceutical compositions, methods of making and methods of administration
NO975634L (no) Stabile farmasöytiske preparater inneholdende tiludronathydrater og fremgangsmåte for fremstilling av farmasöytiske preparater
HRP20030762A2 (en) A stable pharmaceutical formulation comprising torsemide modofication ii
WO1999047172A3 (en) Oral pharmaceutical compositions to be taken without liquids, which contain inclusion complexes
GEP20043377B (en) Pharmaceutical Complex
WO2003013441A3 (en) Levothyroxine compositions and methods
EP1273301A3 (en) Pharmaceutical preparations based on active ingredients susceptible to illict administration
YU28404A (sh) Brzo topljiva formulacija za oralno doziranje
HU0100122D0 (en) Use of tiludronic acid and derivatives thereof in poultry for preparation of a medicinal product for preventing and treating osteoporosis
NO964775L (no) Fast farmasöytisk adenosinholdig preparat