UA102988C2 - ВЫДЕЛЕННОЕ АНТИТЕЛО ЧЕЛОВЕКА ИЛИ ЕГО АНТИГЕН-СВЯЗЫВАЮЩАЯ ЧАСТЬ, КОТОРАЯ СВЯЗЫВАЕТ TNFα ЧЕЛОВЕКА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, В КОТОРОМ АКТИВНОСТЬ TNFα ЯВЛЯЕТСЯ ВРЕДНОЙ - Google Patents

ВЫДЕЛЕННОЕ АНТИТЕЛО ЧЕЛОВЕКА ИЛИ ЕГО АНТИГЕН-СВЯЗЫВАЮЩАЯ ЧАСТЬ, КОТОРАЯ СВЯЗЫВАЕТ TNFα ЧЕЛОВЕКА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, В КОТОРОМ АКТИВНОСТЬ TNFα ЯВЛЯЕТСЯ ВРЕДНОЙ

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Publication number
UA102988C2
UA102988C2 UAA200805824A UAA200805824A UA102988C2 UA 102988 C2 UA102988 C2 UA 102988C2 UA A200805824 A UAA200805824 A UA A200805824A UA A200805824 A UAA200805824 A UA A200805824A UA 102988 C2 UA102988 C2 UA 102988C2
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Ukraine
Prior art keywords
tnfα
antigen
pharmaceutical composition
specifically binds
binding portion
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UAA200805824A
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English (en)
Ukrainian (uk)
Inventor
Г. Салфельд Йохен
Дж. Аллен Дебора
Каймаккалан Зехра
Лабковски Борис
А. Манкович Джон
Т.Макгиннисс Брайан
Дж. Робертс Эндрю
Сакорафас Поль
Р.Й.М. Хогенбом Хендрикус
Шоэнхаут Дэвид
Дж. Вон Тристан
Уайт Майкл
Дж. Уилтон Элисон
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Эбботт Биотекнолоджи Лтд.
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Application filed by Эбботт Биотекнолоджи Лтд. filed Critical Эбботт Биотекнолоджи Лтд.
Publication of UA102988C2 publication Critical patent/UA102988C2/ru

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Abstract

Изобретение относится к антиген-связующей части антитела, которая связывает TNFα человека, dAb фрагменту выделенного антитела человека, который связывает TNFα человека, выделенному антителу человека, фармацевтической композиции, способу лечения заболевания, изолированной нуклеиновой кислоте, рекомбинантному вектору экспрессии, клетке-хозяину, способу синтеза антитела.
UAA200805824A 1996-02-09 1997-02-10 ВЫДЕЛЕННОЕ АНТИТЕЛО ЧЕЛОВЕКА ИЛИ ЕГО АНТИГЕН-СВЯЗЫВАЮЩАЯ ЧАСТЬ, КОТОРАЯ СВЯЗЫВАЕТ TNFα ЧЕЛОВЕКА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, В КОТОРОМ АКТИВНОСТЬ TNFα ЯВЛЯЕТСЯ ВРЕДНОЙ UA102988C2 (ru)

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Application Number Priority Date Filing Date Title
US08/599,226 US6090382A (en) 1996-02-09 1996-02-09 Human antibodies that bind human TNFα

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UA102988C2 true UA102988C2 (ru) 2013-09-10

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UAA201205653A UA111707C2 (uk) 1996-02-09 1997-02-10 Застосування виділеного анти-tnf-альфа антитіла людини
UAA200805824A UA102988C2 (ru) 1996-02-09 1997-02-10 ВЫДЕЛЕННОЕ АНТИТЕЛО ЧЕЛОВЕКА ИЛИ ЕГО АНТИГЕН-СВЯЗЫВАЮЩАЯ ЧАСТЬ, КОТОРАЯ СВЯЗЫВАЕТ TNFα ЧЕЛОВЕКА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, В КОТОРОМ АКТИВНОСТЬ TNFα ЯВЛЯЕТСЯ ВРЕДНОЙ

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UAA201205653A UA111707C2 (uk) 1996-02-09 1997-02-10 Застосування виділеного анти-tnf-альфа антитіла людини

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US (8) US6090382A (ru)
EP (9) EP2930187A1 (ru)
CN (5) CN1935260B (ru)
BR (1) BRPI9715219C8 (ru)
CA (2) CA2389943C (ru)
NZ (4) NZ587678A (ru)
RO (1) RO128628A2 (ru)
RU (1) RU2268266C2 (ru)
UA (2) UA111707C2 (ru)

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