MX2009004351A - Anticuerpos anti-htnfalfa cristalinos. - Google Patents

Anticuerpos anti-htnfalfa cristalinos.

Info

Publication number
MX2009004351A
MX2009004351A MX2009004351A MX2009004351A MX2009004351A MX 2009004351 A MX2009004351 A MX 2009004351A MX 2009004351 A MX2009004351 A MX 2009004351A MX 2009004351 A MX2009004351 A MX 2009004351A MX 2009004351 A MX2009004351 A MX 2009004351A
Authority
MX
Mexico
Prior art keywords
crystals
antibody
htnfalpha
crystalline anti
antibodies
Prior art date
Application number
MX2009004351A
Other languages
English (en)
Inventor
David W Borhani
Gerhard Winter
Wolfgang Fraunhofer
Hans-Juergen Krause
Anette Koenigsdorfer
Stefan Gottschalk
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39364990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009004351(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of MX2009004351A publication Critical patent/MX2009004351A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Communicable Diseases (AREA)
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  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Obesity (AREA)
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Abstract

La presente invención se refiere a un método de cristalización por lotes para cristalizar un anticuerpo anti5 hTNFalfa el cual permite la producción del anticuerpo en una escala industrial; los cristales de anticuerpo tal como se obtienen de acuerdo con el método; las composiciones que contienen los cristales, así como los métodos de uso de los cristales y composiciones.
MX2009004351A 2006-10-27 2007-10-25 Anticuerpos anti-htnfalfa cristalinos. MX2009004351A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85510406P 2006-10-27 2006-10-27
PCT/US2007/022622 WO2008057240A2 (en) 2006-10-27 2007-10-25 Crystalline anti-htnfalpha antibodies

Publications (1)

Publication Number Publication Date
MX2009004351A true MX2009004351A (es) 2009-05-12

Family

ID=39364990

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009004351A MX2009004351A (es) 2006-10-27 2007-10-25 Anticuerpos anti-htnfalfa cristalinos.

Country Status (22)

Country Link
US (4) US8034906B2 (es)
EP (2) EP2684895A1 (es)
JP (2) JP2010507670A (es)
KR (2) KR20090101893A (es)
CN (2) CN104072612A (es)
AR (1) AR063429A1 (es)
AU (1) AU2007318120B2 (es)
BR (1) BRPI0717335A2 (es)
CA (1) CA2667655A1 (es)
CL (1) CL2007003094A1 (es)
ES (1) ES2442258T3 (es)
HK (1) HK1129400A1 (es)
IL (1) IL198223A (es)
MX (1) MX2009004351A (es)
NZ (3) NZ613356A (es)
PE (2) PE20120663A1 (es)
RU (2) RU2486296C2 (es)
SG (1) SG176427A1 (es)
TW (2) TW201429987A (es)
UY (1) UY30662A1 (es)
WO (1) WO2008057240A2 (es)
ZA (1) ZA201306383B (es)

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US20090280065A1 (en) * 2006-04-10 2009-11-12 Willian Mary K Uses and Compositions for Treatment of Psoriasis
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US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
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GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US20060083741A1 (en) * 2004-10-08 2006-04-20 Hoffman Rebecca S Treatment of respiratory syncytial virus (RSV) infection
CA2903138A1 (en) 2005-05-16 2006-11-23 Abbvie Biotechnology Ltd. Use of tnfa inhibitor for treatment of erosive polyarthritis
EP3673919A1 (en) 2005-06-14 2020-07-01 Amgen Inc. Self-buffering protein formulations
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EP2089428A4 (en) 2010-11-03
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