MX339809B - Metodo para preparar anticuerpos con propiedades mejoradas. - Google Patents

Metodo para preparar anticuerpos con propiedades mejoradas.

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Publication number
MX339809B
MX339809B MX2012013771A MX2012013771A MX339809B MX 339809 B MX339809 B MX 339809B MX 2012013771 A MX2012013771 A MX 2012013771A MX 2012013771 A MX2012013771 A MX 2012013771A MX 339809 B MX339809 B MX 339809B
Authority
MX
Mexico
Prior art keywords
improved properties
preparing antibodies
antibodies
preparing
mutations
Prior art date
Application number
MX2012013771A
Other languages
English (en)
Other versions
MX2012013771A (es
Inventor
Liming Liu
Terrance A Stadheim
Dongxing Zha
Original Assignee
Merck Sharp & Dohme Corp *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme Corp * filed Critical Merck Sharp & Dohme Corp *
Publication of MX2012013771A publication Critical patent/MX2012013771A/es
Publication of MX339809B publication Critical patent/MX339809B/es

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Abstract

La presente invención se refiere a métodos y composiciones para la producción de polipéptidos que contienen una región Fc que tienen propiedades mejoradas y que comprenden las mutaciones en las posiciones 243 y 264 de la región Fc.
MX2012013771A 2010-05-27 2011-05-25 Metodo para preparar anticuerpos con propiedades mejoradas. MX339809B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34896810P 2010-05-27 2010-05-27
PCT/US2011/037826 WO2011149999A2 (en) 2010-05-27 2011-05-25 Method for preparing antibodies having improved properties

Publications (2)

Publication Number Publication Date
MX2012013771A MX2012013771A (es) 2013-01-24
MX339809B true MX339809B (es) 2016-06-09

Family

ID=45004737

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AU2011258425B2 (en) 2015-12-10
US10858686B2 (en) 2020-12-08
BR112012030179A8 (pt) 2023-03-14
RU2012157270A (ru) 2014-07-10
RU2604811C2 (ru) 2016-12-10
CN103080130A (zh) 2013-05-01
EP2576616A4 (en) 2014-05-21
KR20130109983A (ko) 2013-10-08
US20210047670A1 (en) 2021-02-18
US20160083765A1 (en) 2016-03-24
CO6640254A2 (es) 2013-03-22
JP2016155838A (ja) 2016-09-01
IL223018A0 (en) 2013-02-03
CA2799595A1 (en) 2011-12-01
BR112012030179A2 (pt) 2016-11-01
WO2011149999A3 (en) 2012-01-19
US9187552B2 (en) 2015-11-17
WO2011149999A2 (en) 2011-12-01
TW201202266A (en) 2012-01-16
CN103080130B (zh) 2016-08-17
JP2013529908A (ja) 2013-07-25
KR101818274B1 (ko) 2018-01-12
MX2012013771A (es) 2013-01-24
US20180346951A1 (en) 2018-12-06
CA2799595C (en) 2022-08-16
EP2576616A2 (en) 2013-04-10
US20130071390A1 (en) 2013-03-21
JP5956982B2 (ja) 2016-07-27
NZ603883A (en) 2015-01-30
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AU2011258425A1 (en) 2012-12-20
US11959118B2 (en) 2024-04-16

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