TWI792596B - 新穎脂肪酸及其於共軛至生物分子之用途 - Google Patents

新穎脂肪酸及其於共軛至生物分子之用途 Download PDF

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TWI792596B
TWI792596B TW110136772A TW110136772A TWI792596B TW I792596 B TWI792596 B TW I792596B TW 110136772 A TW110136772 A TW 110136772A TW 110136772 A TW110136772 A TW 110136772A TW I792596 B TWI792596 B TW I792596B
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conjugate
mmol
peptide
acid
gdf15
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TW202204384A (zh
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大衛 溫英傑 伯尼斯
山田健
去克溫杜 伊比邦久
阿洛克許 都塔羅伊
路易斯 克萊爾 可曼
亞立山卓 馬歇爾 布魯斯
愛咪 瑞察德森 優瑟拉
佛瑞德利克 查克利
強 元
樓長剛
艾倫 肯特
愛薇洛普 博斯
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瑞士商諾華公司
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TW110136772A 2014-06-23 2015-06-22 新穎脂肪酸及其於共軛至生物分子之用途 TWI792596B (zh)

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US201462015862P 2014-06-23 2014-06-23
US62/015,862 2014-06-23
US201462082327P 2014-11-20 2014-11-20
US62/082,327 2014-11-20
US201562107016P 2015-01-23 2015-01-23
US62/107,016 2015-01-23

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TW109123095A TWI750725B (zh) 2014-06-23 2015-06-22 新穎脂肪酸及其於共軛至生物分子之用途
TW110136772A TWI792596B (zh) 2014-06-23 2015-06-22 新穎脂肪酸及其於共軛至生物分子之用途
TW104120074A TWI701048B (zh) 2014-06-23 2015-06-22 新穎脂肪酸及其於共軛至生物分子之用途

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US (4) US10588980B2 (fr)
EP (2) EP3988170A1 (fr)
JP (5) JP6636959B2 (fr)
KR (2) KR102559975B1 (fr)
CN (3) CN107073130B (fr)
AP (1) AP2016009585A0 (fr)
AU (1) AU2015280351C1 (fr)
CA (1) CA2953480A1 (fr)
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DK (1) DK3157571T3 (fr)
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TW200936156A (en) 2008-01-28 2009-09-01 Novartis Ag Methods and compositions using Klotho-FGF fusion polypeptides
US8420088B2 (en) 2008-01-28 2013-04-16 Novartis Ag Methods and compositions using FGF23 fusion polypeptides
JP5977814B2 (ja) 2011-04-08 2016-08-24 アムジエン・インコーポレーテツド 増殖分化因子15(gdf−15)を使用して代謝障害を治療または改善する方法
NZ754961A (en) 2013-07-31 2022-04-29 Amgen Inc Growth differentiation factor 15 (gdf-15) constructs
US10588980B2 (en) 2014-06-23 2020-03-17 Novartis Ag Fatty acids and their use in conjugation to biomolecules
WO2016088059A1 (fr) 2014-12-04 2016-06-09 Novartis Ag Procédés et compositions employant des polypeptides variants de klotho
EA201791668A1 (ru) * 2015-01-23 2017-11-30 Новартис Аг Синтетические конъюгаты апелина с жирной кислотой с улучшенным периодом полураспада
CN108367053A (zh) * 2015-12-22 2018-08-03 诺华股份有限公司 使用生长分化因子15(gdf-15)治疗或改善代谢性疾病的方法
AU2017210726B2 (en) 2016-01-31 2023-08-03 University Of Massachusetts Branched oligonucleotides
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