TWI705976B - 抗介白素-33抗體及其用途 - Google Patents

抗介白素-33抗體及其用途 Download PDF

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TWI705976B
TWI705976B TW104137071A TW104137071A TWI705976B TW I705976 B TWI705976 B TW I705976B TW 104137071 A TW104137071 A TW 104137071A TW 104137071 A TW104137071 A TW 104137071A TW I705976 B TWI705976 B TW I705976B
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antibody
acid sequence
amino acid
seq
binding
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TW104137071A
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TW201625683A (zh
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菲利浦Ｅ 賀斯
米瑞迪斯 海森
蕭怡君
瑞吉塔 柯斯拉
傑芮Ｒ 娜卡慕拉
黛雅 西夏沙雅
魯克恩 迦配恩 曼諾 凡
宏康 奚
文武 翟
傑克 三世 畢佛
南西 江
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美商建南德克公司
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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TW104137071A 2014-11-10 2015-11-10 抗介白素-33抗體及其用途 TWI705976B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462077876P 2014-11-10 2014-11-10
US62/077,876 2014-11-10
US201562165732P 2015-05-22 2015-05-22
US62/165,732 2015-05-22

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TW201625683A TW201625683A (zh) 2016-07-16
TWI705976B true TWI705976B (zh) 2020-10-01

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US (3) US10093730B2 (enExample)
EP (2) EP3218403B1 (enExample)
JP (1) JP6929771B2 (enExample)
KR (1) KR20170080604A (enExample)
CN (1) CN107172879B (enExample)
AU (1) AU2015346460A1 (enExample)
BR (1) BR112017009728A2 (enExample)
CA (1) CA2960297A1 (enExample)
CO (1) CO2017005650A2 (enExample)
CR (1) CR20170240A (enExample)
EA (1) EA201791029A1 (enExample)
IL (1) IL251248A0 (enExample)
MX (1) MX2017006094A (enExample)
PE (1) PE20170910A1 (enExample)
PH (1) PH12017500861A1 (enExample)
SG (1) SG11201703767XA (enExample)
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WO (1) WO2016077381A1 (enExample)

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WO2013188316A1 (en) * 2012-06-11 2013-12-19 Avalanche Biotechnologies, Inc. Optical regulation of gene expression in the retina
AU2015204674B2 (en) 2014-01-10 2020-09-03 Anaptysbio, Inc. Antibodies directed against interleukin-33 (IL-33)
CA2960297A1 (en) 2014-11-10 2016-05-19 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
CN107109494B (zh) 2014-11-10 2023-10-27 豪夫迈·罗氏有限公司 Il-33介导型疾病的治疗方法和诊断方法
KR102725051B1 (ko) 2015-09-23 2024-11-04 제넨테크, 인크. 항-vegf 항체의 최적화된 변이체들
MX2018013038A (es) 2016-04-27 2019-03-28 Pfizer Anticuerpos anti-il-33, composiciones, metodos y usos de los mismos.
WO2017189805A1 (en) 2016-04-27 2017-11-02 Abbvie Inc. Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
EP3506920A4 (en) * 2016-09-02 2020-05-27 180 Therapeutics LP METHOD FOR TREATING SYSTEMIC FIBROTIC DISEASES WITH A BISPECIFIC IL-33 / TNF ANTIBODY
US20190225682A1 (en) * 2016-09-02 2019-07-25 180 Therapeutics Lp Method of treating localized fibrotic disorders using an il-33/tnf bispecific antibody
JOP20190093A1 (ar) * 2016-10-28 2019-04-25 Lilly Co Eli أجسام مضادة لـ il-33 واستخداماتها
TWI857389B (zh) 2016-12-01 2024-10-01 美商再生元醫藥公司 治療發炎症狀的方法
PE20191548A1 (es) 2017-02-10 2019-10-24 Genentech Inc Anticuerpos contra triptasa, composiciones de estos y usos de estos
AU2018252974B2 (en) 2017-04-13 2024-10-17 Regeneron Pharmaceuticals, Inc. Treatment and inhibition of inflammatory lung diseases in patients having risk alleles in the genes encoding IL33 and IL1RL1
CN118994394A (zh) 2017-06-12 2024-11-22 蓝鳍生物医药公司 抗-il1rap抗体和抗体药物缀合物
PE20211304A1 (es) 2018-02-09 2021-07-20 Genentech Inc Metodos terapeuticos y diagnosticos para enfermedades inflamatorias mediadas por mastocitos
IL277890B2 (en) 2018-04-11 2024-03-01 Regeneron Pharma Methods for quantifying il-33
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