TR200103127T2 - Pravastatinin hazırlanması için mikrobiyal işlem. - Google Patents

Pravastatinin hazırlanması için mikrobiyal işlem.

Info

Publication number
TR200103127T2
TR200103127T2 TR2001/03127T TR200103127T TR200103127T2 TR 200103127 T2 TR200103127 T2 TR 200103127T2 TR 2001/03127 T TR2001/03127 T TR 2001/03127T TR 200103127 T TR200103127 T TR 200103127T TR 200103127 T2 TR200103127 T2 TR 200103127T2
Authority
TR
Turkey
Prior art keywords
compound
formula
preparation
general formula
new
Prior art date
Application number
TR2001/03127T
Other languages
English (en)
Turkish (tr)
Inventor
Jekkel Antonia
Konya Attila
Barta Istvan
Ilkoy Eva
Somogyi Gyorgy
Ambrus Gabor
Horvath Gyula
Albrecht Karoly
M. Szabo Istvan
Mozes Nee Suto Julianna
Salat Janos
Andor Att�La
Birincsik Laszlo
Boros Sandor
Lang Iidiko
Bidlo Nee Igloy Margit
Original Assignee
Institute For Drug Research Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute For Drug Research Ltd. filed Critical Institute For Drug Research Ltd.
Publication of TR200103127T2 publication Critical patent/TR200103127T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TR2001/03127T 1999-02-03 2000-02-03 Pravastatinin hazırlanması için mikrobiyal işlem. TR200103127T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11845899P 1999-02-03 1999-02-03
US13475999P 1999-05-18 1999-05-18

Publications (1)

Publication Number Publication Date
TR200103127T2 true TR200103127T2 (tr) 2002-04-22

Family

ID=26816384

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2001/03127T TR200103127T2 (tr) 1999-02-03 2000-02-03 Pravastatinin hazırlanması için mikrobiyal işlem.
TR2006/00009T TR200600009T2 (tr) 1999-02-03 2000-02-03 Pravastatinin hazırlanması için mikrobiyal işlem.@

Family Applications After (1)

Application Number Title Priority Date Filing Date
TR2006/00009T TR200600009T2 (tr) 1999-02-03 2000-02-03 Pravastatinin hazırlanması için mikrobiyal işlem.@

Country Status (27)

Country Link
EP (1) EP1154979B1 (https=)
JP (2) JP3645491B2 (https=)
KR (2) KR20060061406A (https=)
CN (3) CN1260344C (https=)
AR (2) AR023368A1 (https=)
AT (1) ATE294771T1 (https=)
AU (2) AU774438B2 (https=)
BG (1) BG105778A (https=)
BR (1) BR0009180A (https=)
CA (1) CA2361701C (https=)
CZ (1) CZ20012761A3 (https=)
DE (1) DE60019898T2 (https=)
ES (1) ES2240072T3 (https=)
HK (1) HK1042686B (https=)
HR (1) HRP20010577B1 (https=)
HU (1) HUP0200650A3 (https=)
IL (1) IL144697A0 (https=)
IS (1) IS6036A (https=)
MX (1) MXPA01007807A (https=)
NO (1) NO20013818L (https=)
PL (1) PL350317A1 (https=)
PT (1) PT1154979E (https=)
RU (1) RU2004127981A (https=)
SK (1) SK10932001A3 (https=)
TR (2) TR200103127T2 (https=)
WO (1) WO2000046175A1 (https=)
YU (1) YU55701A (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20305A (sl) † 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
YU39102A (sh) * 1999-11-30 2006-01-16 Biogal Gyogyszergyar Rt Postupak dobijanja statina iz fermentacione smeše
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
IL150187A0 (en) 1999-12-14 2002-12-01 Biogal Pharmaceutical Co Ltd Novel forms of pravastatin sodium
CN1468098A (zh) * 2000-10-05 2004-01-14 �ݰ¸Ƕ�ҩ�����޹�˾ 基本上无普伐他汀内酯和表普伐他汀的普伐他汀钠和包含普伐他汀钠的组合物
JP2003026634A (ja) * 2001-07-17 2003-01-29 Mercian Corp プラバスタチンナトリウム塩の製造方法
JP3463875B2 (ja) 2001-08-06 2003-11-05 三共株式会社 プラバスタチンを精製する方法
JP3422791B2 (ja) 2002-08-06 2003-06-30 三共株式会社 プラバスタチンの単離・精製方法
KR100540761B1 (ko) * 2002-08-09 2006-01-16 코바이오텍 (주) 프라바스타틴 나트륨의 제조방법
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
WO2004096785A1 (ja) * 2003-04-25 2004-11-11 Nippon Chemiphar Co., Ltd. （２s，３s）－３－［［（１s）－１－イソブトキシメチル－３－メチルブチル］カルバモイル］オキシラン－２－カルボン酸の塩
CN1244688C (zh) 2003-07-09 2006-03-08 上海天伟生物制药有限公司 生产普伐他汀钠的微生物和方法
DE602004017461D1 (de) 2003-11-24 2008-12-11 Teva Gyogyszergyar Zartkoeruen Verfahren zur reinigung von pravastatin
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
EP2274267B1 (en) * 2008-04-02 2012-01-04 DSM IP Assets B.V. Pravastatin extraction
EP3714959A1 (en) * 2019-03-29 2020-09-30 Basf Se Isolation of small molecules from the fermentation broth of a eukaryotic microorganism
CN117164541B (zh) * 2022-05-27 2025-09-30 黑龙江华瑞生物科技有限公司 一种从美伐他汀母液中分离纯化美伐他汀的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997036996A2 (en) * 1996-03-28 1997-10-09 Gist-Brocades B.V. Process for the preparation of a granular microbial biomass and isolation of valuable compounds therefrom

Also Published As

Publication number Publication date
AR023368A1 (es) 2002-09-04
MXPA01007807A (es) 2003-06-04
KR20060061406A (ko) 2006-06-07
CZ20012761A3 (cs) 2002-05-15
IL144697A0 (en) 2002-06-30
SK10932001A3 (sk) 2002-06-04
JP3645491B2 (ja) 2005-05-11
CN1590363A (zh) 2005-03-09
EP1154979B1 (en) 2005-05-04
CN1537935A (zh) 2004-10-20
JP2005047924A (ja) 2005-02-24
NO20013818D0 (no) 2001-08-03
HUP0200650A3 (en) 2008-03-28
ATE294771T1 (de) 2005-05-15
HRP20010577A2 (en) 2002-12-31
TR200600009T2 (tr) 2006-08-21
KR20010112257A (ko) 2001-12-20
CN1347400A (zh) 2002-05-01
EP1154979A1 (en) 2001-11-21
JP4197312B2 (ja) 2008-12-17
CA2361701C (en) 2007-04-10
AU2004214559A1 (en) 2004-10-21
CN1260344C (zh) 2006-06-21
IS6036A (is) 2001-08-02
HK1042686B (en) 2005-10-14
AR061765A2 (es) 2008-09-17
BR0009180A (pt) 2002-03-26
CA2361701A1 (en) 2000-08-10
CN1177793C (zh) 2004-12-01
ES2240072T3 (es) 2005-10-16
HK1042686A1 (en) 2002-08-23
DE60019898D1 (de) 2005-06-09
AU3356700A (en) 2000-08-25
EP1154979A4 (en) 2004-05-26
BG105778A (bg) 2002-05-31
JP2002535977A (ja) 2002-10-29
HRP20010577B1 (en) 2005-12-31
RU2004127981A (ru) 2006-03-10
KR100648541B1 (ko) 2006-11-24
HUP0200650A2 (en) 2002-08-28
AU774438B2 (en) 2004-06-24
DE60019898T2 (de) 2006-08-10
YU55701A (sh) 2004-07-15
PL350317A1 (en) 2002-12-02
WO2000046175A1 (en) 2000-08-10
PT1154979E (pt) 2005-08-31
NO20013818L (no) 2001-10-03

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