NO20013818D0 - Mikrobiell fremgangsmåte for fremstilling av pravastatin - Google Patents

Mikrobiell fremgangsmåte for fremstilling av pravastatin

Info

Publication number
NO20013818D0
NO20013818D0 NO20013818A NO20013818A NO20013818D0 NO 20013818 D0 NO20013818 D0 NO 20013818D0 NO 20013818 A NO20013818 A NO 20013818A NO 20013818 A NO20013818 A NO 20013818A NO 20013818 D0 NO20013818 D0 NO 20013818D0
Authority
NO
Norway
Prior art keywords
pravastatin
preparation
microbial process
microbial
Prior art date
Application number
NO20013818A
Other languages
English (en)
Other versions
NO20013818L (no
Inventor
Antonia Jekkel
Attila Konya
Istvan Barta
Eva Ilkoy
Gyorgy Somogyi
Gabor Ambrus
Gyula Horvath
Karoly Albrecht
Istvan Mihaly Szabo
Julianna Mozes
Janos Salat
Attila Andor
Laszlo Birincsik
Sandor Boros
Ildiko Lang
Margit Bidlo
Original Assignee
Inst Drug Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Drug Res Ltd filed Critical Inst Drug Res Ltd
Publication of NO20013818D0 publication Critical patent/NO20013818D0/no
Publication of NO20013818L publication Critical patent/NO20013818L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20013818A 1999-02-03 2001-08-03 Mikrobiell fremgangsmåte for fremstilling av pravastatin NO20013818L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11845899P 1999-02-03 1999-02-03
US13475999P 1999-05-18 1999-05-18
PCT/US2000/002993 WO2000046175A1 (en) 1999-02-03 2000-02-03 Microbial process for preparing pravastatin

Publications (2)

Publication Number Publication Date
NO20013818D0 true NO20013818D0 (no) 2001-08-03
NO20013818L NO20013818L (no) 2001-10-03

Family

ID=26816384

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013818A NO20013818L (no) 1999-02-03 2001-08-03 Mikrobiell fremgangsmåte for fremstilling av pravastatin

Country Status (27)

Country Link
EP (1) EP1154979B1 (no)
JP (2) JP3645491B2 (no)
KR (2) KR100648541B1 (no)
CN (3) CN1590363A (no)
AR (2) AR023368A1 (no)
AT (1) ATE294771T1 (no)
AU (2) AU774438B2 (no)
BG (1) BG105778A (no)
BR (1) BR0009180A (no)
CA (1) CA2361701C (no)
CZ (1) CZ20012761A3 (no)
DE (1) DE60019898T2 (no)
ES (1) ES2240072T3 (no)
HK (1) HK1042686B (no)
HR (1) HRP20010577B1 (no)
HU (1) HUP0200650A3 (no)
IL (1) IL144697A0 (no)
IS (1) IS6036A (no)
MX (1) MXPA01007807A (no)
NO (1) NO20013818L (no)
PL (1) PL350317A1 (no)
PT (1) PT1154979E (no)
RU (1) RU2004127981A (no)
SK (1) SK10932001A3 (no)
TR (2) TR200103127T2 (no)
WO (1) WO2000046175A1 (no)
YU (1) YU55701A (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20305A (sl) * 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
RU2002114072A (ru) 1999-11-30 2004-07-20 Биогал Джиоджисзерджиар РТ (HU) Способ выделения соединений статина из ферментационного бульона
HUP0204005A3 (en) 1999-12-14 2003-05-28 Teva Gyogyszergyar Zartkoeruee Novel forms of pravastatin sodium, process for their preparation and pharmaceutical compositions containing them
HUP0400913A2 (en) * 2000-10-05 2006-11-28 Biogal Gyogyszergyar Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
JP2003026634A (ja) * 2001-07-17 2003-01-29 Mercian Corp プラバスタチンナトリウム塩の製造方法
KR100540761B1 (ko) * 2002-08-09 2006-01-16 코바이오텍 (주) 프라바스타틴 나트륨의 제조방법
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
JP4616168B2 (ja) * 2003-04-25 2011-01-19 日本ケミファ株式会社 （２ｓ，３ｓ）−３−［［（１ｓ）−１−イソブトキシメチル−３−メチルブチル］カルバモイル］オキシラン−２−カルボン酸の塩
CN1244688C (zh) 2003-07-09 2006-03-08 上海天伟生物制药有限公司 生产普伐他汀钠的微生物和方法
WO2005051372A2 (en) 2003-11-24 2005-06-09 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Method of purifying pravastatin
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
WO2009121870A1 (en) * 2008-04-02 2009-10-08 Dsm Ip Assets B.V. Pravastatin extraction
EP3714959A1 (en) * 2019-03-29 2020-09-30 Basf Se Isolation of small molecules from the fermentation broth of a eukaryotic microorganism

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101928213B (zh) * 1996-03-28 2012-12-05 Dsmip资产有限公司 粒状微生物生物质的制备及其有价值的化合物的分离方法

Also Published As

Publication number Publication date
AU3356700A (en) 2000-08-25
JP2005047924A (ja) 2005-02-24
CN1347400A (zh) 2002-05-01
JP4197312B2 (ja) 2008-12-17
CA2361701C (en) 2007-04-10
IL144697A0 (en) 2002-06-30
BG105778A (bg) 2002-05-31
KR20060061406A (ko) 2006-06-07
HK1042686B (zh) 2005-10-14
ATE294771T1 (de) 2005-05-15
HRP20010577A2 (en) 2002-12-31
IS6036A (is) 2001-08-02
JP3645491B2 (ja) 2005-05-11
AR061765A2 (es) 2008-09-17
WO2000046175A1 (en) 2000-08-10
TR200103127T2 (tr) 2002-04-22
CZ20012761A3 (cs) 2002-05-15
EP1154979A1 (en) 2001-11-21
HUP0200650A2 (en) 2002-08-28
HRP20010577B1 (en) 2005-12-31
DE60019898D1 (de) 2005-06-09
BR0009180A (pt) 2002-03-26
JP2002535977A (ja) 2002-10-29
CN1590363A (zh) 2005-03-09
EP1154979B1 (en) 2005-05-04
CN1260344C (zh) 2006-06-21
AR023368A1 (es) 2002-09-04
NO20013818L (no) 2001-10-03
TR200600009T2 (tr) 2006-08-21
KR100648541B1 (ko) 2006-11-24
CN1537935A (zh) 2004-10-20
CN1177793C (zh) 2004-12-01
KR20010112257A (ko) 2001-12-20
YU55701A (sh) 2004-07-15
RU2004127981A (ru) 2006-03-10
SK10932001A3 (sk) 2002-06-04
PL350317A1 (en) 2002-12-02
PT1154979E (pt) 2005-08-31
CA2361701A1 (en) 2000-08-10
HK1042686A1 (en) 2002-08-23
DE60019898T2 (de) 2006-08-10
MXPA01007807A (es) 2003-06-04
EP1154979A4 (en) 2004-05-26
ES2240072T3 (es) 2005-10-16
HUP0200650A3 (en) 2008-03-28
AU774438B2 (en) 2004-06-24
AU2004214559A1 (en) 2004-10-21

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