IS6036A - Örveruaðferð við að framleiða pravastatín - Google Patents

Örveruaðferð við að framleiða pravastatín

Info

Publication number
IS6036A
IS6036A IS6036A IS6036A IS6036A IS 6036 A IS6036 A IS 6036A IS 6036 A IS6036 A IS 6036A IS 6036 A IS6036 A IS 6036A IS 6036 A IS6036 A IS 6036A
Authority
IS
Iceland
Prior art keywords
microbiological method
producing pravastatin
pravastatin
producing
microbiological
Prior art date
Application number
IS6036A
Other languages
English (en)
Inventor
Jekkel Antonia
Konya Attila
Barta Istvan
Ilkoy Eva
Somogyi Gyorgy
Ambrus Gabor
Horvath Gyula
Albrecht Karoly
M. Szabo Istvan
Mozes Nee Suto Julianna
Salat Janos
Andor Attila
Birincsik Laszlo
Boros Sandor
Lang Ildiko
Bidlo Nee Igloy Margit
Original Assignee
Institute For Drug Research Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute For Drug Research Ltd. filed Critical Institute For Drug Research Ltd.
Publication of IS6036A publication Critical patent/IS6036A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS6036A 1999-02-03 2001-08-02 Örveruaðferð við að framleiða pravastatín IS6036A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11845899P 1999-02-03 1999-02-03
US13475999P 1999-05-18 1999-05-18
PCT/US2000/002993 WO2000046175A1 (en) 1999-02-03 2000-02-03 Microbial process for preparing pravastatin

Publications (1)

Publication Number Publication Date
IS6036A true IS6036A (is) 2001-08-02

Family

ID=26816384

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6036A IS6036A (is) 1999-02-03 2001-08-02 Örveruaðferð við að framleiða pravastatín

Country Status (27)

Country Link
EP (1) EP1154979B1 (is)
JP (2) JP3645491B2 (is)
KR (2) KR20060061406A (is)
CN (3) CN1590363A (is)
AR (2) AR023368A1 (is)
AT (1) ATE294771T1 (is)
AU (2) AU774438B2 (is)
BG (1) BG105778A (is)
BR (1) BR0009180A (is)
CA (1) CA2361701C (is)
CZ (1) CZ20012761A3 (is)
DE (1) DE60019898T2 (is)
ES (1) ES2240072T3 (is)
HK (1) HK1042686B (is)
HR (1) HRP20010577B1 (is)
HU (1) HUP0200650A3 (is)
IL (1) IL144697A0 (is)
IS (1) IS6036A (is)
MX (1) MXPA01007807A (is)
NO (1) NO20013818L (is)
PL (1) PL350317A1 (is)
PT (1) PT1154979E (is)
RU (1) RU2004127981A (is)
SK (1) SK10932001A3 (is)
TR (2) TR200103127T2 (is)
WO (1) WO2000046175A1 (is)
YU (1) YU55701A (is)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20305A (sl) * 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
SK7342002A3 (en) * 1999-11-30 2004-03-02 Biogal Gyogyszergyar Process for recovering statin compounds from a fermentation broth
KR20020062340A (ko) 1999-12-14 2002-07-25 비오갈 기오기스제르갸르 알티. 신규 형태의 프라바스타틴 나트륨
PL361230A1 (en) * 2000-10-05 2004-10-04 Biogal Gyogyszergyar Rt. Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
JP2003026634A (ja) * 2001-07-17 2003-01-29 Mercian Corp プラバスタチンナトリウム塩の製造方法
JP3463875B2 (ja) 2001-08-06 2003-11-05 三共株式会社 プラバスタチンを精製する方法
JP3422791B2 (ja) 2002-08-06 2003-06-30 三共株式会社 プラバスタチンの単離・精製方法
KR100540761B1 (ko) * 2002-08-09 2006-01-16 코바이오텍 (주) 프라바스타틴 나트륨의 제조방법
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
JP4616168B2 (ja) * 2003-04-25 2011-01-19 日本ケミファ株式会社 （２ｓ，３ｓ）−３−［［（１ｓ）−１−イソブトキシメチル−３−メチルブチル］カルバモイル］オキシラン−２−カルボン酸の塩
CN1244688C (zh) 2003-07-09 2006-03-08 上海天伟生物制药有限公司 生产普伐他汀钠的微生物和方法
TWI319707B (en) 2003-11-24 2010-01-21 Method of purifying pravastatin
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
EP2274267B1 (en) * 2008-04-02 2012-01-04 DSM IP Assets B.V. Pravastatin extraction
EP3714959A1 (en) * 2019-03-29 2020-09-30 Basf Se Isolation of small molecules from the fermentation broth of a eukaryotic microorganism
CN117164541B (zh) * 2022-05-27 2025-09-30 黑龙江华瑞生物科技有限公司 一种从美伐他汀母液中分离纯化美伐他汀的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104017734A (zh) * 1996-03-28 2014-09-03 Dsmip资产有限公司 粒状微生物生物质的制备及其有价值的化合物的分离方法

Also Published As

Publication number Publication date
EP1154979A4 (en) 2004-05-26
YU55701A (sh) 2004-07-15
KR20010112257A (ko) 2001-12-20
CN1260344C (zh) 2006-06-21
DE60019898D1 (de) 2005-06-09
SK10932001A3 (sk) 2002-06-04
AU774438B2 (en) 2004-06-24
KR100648541B1 (ko) 2006-11-24
MXPA01007807A (es) 2003-06-04
CN1177793C (zh) 2004-12-01
BG105778A (bg) 2002-05-31
HRP20010577A2 (en) 2002-12-31
CN1347400A (zh) 2002-05-01
CA2361701A1 (en) 2000-08-10
CN1537935A (zh) 2004-10-20
AR023368A1 (es) 2002-09-04
HK1042686B (en) 2005-10-14
EP1154979A1 (en) 2001-11-21
KR20060061406A (ko) 2006-06-07
JP3645491B2 (ja) 2005-05-11
ATE294771T1 (de) 2005-05-15
JP2002535977A (ja) 2002-10-29
HUP0200650A2 (en) 2002-08-28
JP4197312B2 (ja) 2008-12-17
TR200600009T2 (tr) 2006-08-21
PL350317A1 (en) 2002-12-02
CA2361701C (en) 2007-04-10
HK1042686A1 (en) 2002-08-23
JP2005047924A (ja) 2005-02-24
CN1590363A (zh) 2005-03-09
CZ20012761A3 (cs) 2002-05-15
NO20013818L (no) 2001-10-03
NO20013818D0 (no) 2001-08-03
WO2000046175A1 (en) 2000-08-10
BR0009180A (pt) 2002-03-26
EP1154979B1 (en) 2005-05-04
DE60019898T2 (de) 2006-08-10
AU2004214559A1 (en) 2004-10-21
TR200103127T2 (tr) 2002-04-22
PT1154979E (pt) 2005-08-31
RU2004127981A (ru) 2006-03-10
AR061765A2 (es) 2008-09-17
AU3356700A (en) 2000-08-25
HRP20010577B1 (en) 2005-12-31
HUP0200650A3 (en) 2008-03-28
IL144697A0 (en) 2002-06-30
ES2240072T3 (es) 2005-10-16

Similar Documents

Publication Publication Date Title
PT1173431E (pt) Metodo de preparacao do citalopram
DE60028849D1 (de) Sterilisationsmethode
NO20021382D0 (no) Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser
PT1150966E (pt) Metodo de preparacao de 5-cianoftalido
ITMI991579A0 (it) Metodo per la preparazione di citalopram
ITMI991581A0 (it) Metodo per la preparazione di citalopram
ID26990A (id) Metode pembuatan dimetilnaftalena
IS6036A (is) Örveruaðferð við að framleiða pravastatín
ID27191A (id) Metode untuk pengobatan insomnia
ID28344A (id) Metode penggunaan kembali kepingan poliester
NO20015316L (no) Optimalisering av fermenteringsprosess
ID28577A (id) Metoda pemilihan waktu kalibrasi
HUP0303106A3 (en) Method of purifying pravastatin
FI990234L (fi) MenetelmäKIinnirullauksessa
PT1228056E (pt) Metodo de preparacao de citaloprame
FI981615A7 (fi) Mannitolin valmistusmenetelmä immobilisoituja mikro-organismeja käyttäen
FI991488L (fi) Menetelmä melatoniinipitoisen maidon tuottamiseksi
NO20020183D0 (no) Fremgangsmåte for deacylering av lipodepsipeptider
ID30126A (id) METODE UNTUK MENGHASILKAN SIKLO-(Asp-DPhe-NMeVal-Arg-Gly)
EE200200053A (et) Isoretinoiini valmistamise protsess
UA33967A (uk) Спосіб виготовлення коньяку
UA25613A (uk) Спосіб виробhицтва пива
SE9903010D0 (sv) Method for screening
SE9903234D0 (sv) Method of making paperclips
UA34042A (uk) Спосіб моделювання гідроуретеронефрозу