ES2123948T3 - Compuestos antiparasitarios de pirrolobenzoxazina. - Google Patents

Compuestos antiparasitarios de pirrolobenzoxazina.

Info

Publication number
ES2123948T3
ES2123948T3 ES95905762T ES95905762T ES2123948T3 ES 2123948 T3 ES2123948 T3 ES 2123948T3 ES 95905762 T ES95905762 T ES 95905762T ES 95905762 T ES95905762 T ES 95905762T ES 2123948 T3 ES2123948 T3 ES 2123948T3
Authority
ES
Spain
Prior art keywords
pct
formula
pyrrolobenzoxazine
sec
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95905762T
Other languages
English (en)
Inventor
Yasuhiro Kojima
Yuji Yamauchi
Nakao Kojima
Bernard F Bishop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2123948T3 publication Critical patent/ES2123948T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION SUMINISTRA COMPUESTOS DE LA FORMULA QUIMICA (I) O SUS SALES FARMACOLOGICAMENTE ACEPTABLES, EN DONDE R ES HIDROGENO O CLORO. TAMBIEN LA INVENCION SUMINISTRA UN PROCESO PARA LA PREPARACION DEL COMPUESTO DE LA FORMULA (I), QUE COMPRENDE EL CULTIVO DE MICROORGANISMOS QUE TIENEN LAS CARACTERISTICAS IDENTIFICATIVAS DEL "ASPERGILLUS FISCHERI" VAR. "THERMOMUTATUS" ATCC 18618 O SIMILAR, Y AISLANDO ENTONCES EL COMPUESTO DE LA FORMULA (I) A PARTIR DEL CALDO DE FERMENTACION. LOS COMPUESTOS DE PIRROLOBENZOXACINA DE LA FORMULA (I) DE LA INVENCION TIENEN AMPLIA ACTIVIDAD ANTIPARASITICA, Y POR LO TANTO SON UTILES COMO AGENTES ANTIPARASITICOS, ESPECIALMENTE COMO ANTIHELMINTICOS.
ES95905762T 1994-01-14 1995-01-11 Compuestos antiparasitarios de pirrolobenzoxazina. Expired - Lifetime ES2123948T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1582594 1994-01-14

Publications (1)

Publication Number Publication Date
ES2123948T3 true ES2123948T3 (es) 1999-01-16

Family

ID=11899636

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95905762T Expired - Lifetime ES2123948T3 (es) 1994-01-14 1995-01-11 Compuestos antiparasitarios de pirrolobenzoxazina.

Country Status (11)

Country Link
US (1) US5801023A (es)
EP (1) EP0739344B1 (es)
JP (1) JP2767161B2 (es)
AT (1) ATE173264T1 (es)
AU (1) AU684334B2 (es)
CA (1) CA2181168C (es)
DE (1) DE69505946T2 (es)
DK (1) DK0739344T3 (es)
ES (1) ES2123948T3 (es)
NZ (1) NZ278143A (es)
WO (1) WO1995019363A1 (es)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
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GB0303439D0 (en) 2003-02-14 2003-03-19 Pfizer Ltd Antiparasitic terpene alkaloids
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KR20130034011A (ko) 2010-02-22 2013-04-04 신젠타 파티서페이션즈 아게 살곤충 화합물로서의 디하이드로푸란 유도체
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WO2012049327A2 (en) 2010-10-15 2012-04-19 Syngenta Participations Ag Pesticidal mixtures
US20130269064A1 (en) 2010-11-23 2013-10-10 Syngenta Participations Ag Insecticidal compounds
UY33808A (es) 2010-12-17 2012-07-31 Syngenta Participations Ag Compuestos insecticidas
EP2673270A1 (en) 2011-02-09 2013-12-18 Syngenta Participations AG Insecticidal compounds
CN103443068A (zh) 2011-03-22 2013-12-11 先正达参股股份有限公司 杀虫化合物
AU2012257690A1 (en) 2011-05-18 2013-11-21 Syngenta Participations Ag Insecticidal compounds based on arylthioacetamide derivatives
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US9078444B2 (en) 2011-09-13 2015-07-14 Syngenta Participations Ag Isothiazoline derivatives as insecticidal compounds
JP2014534182A (ja) 2011-10-03 2014-12-18 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物としてのイソオキサゾリン誘導体
UA112556C2 (uk) 2011-10-03 2016-09-26 Сінгента Партісіпейшнс Аг Інсектицидні похідні 2-метоксибензамідів
WO2013135674A1 (en) 2012-03-12 2013-09-19 Syngenta Participations Ag Insecticidal 2-aryl-acetamide compounds
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US9402395B2 (en) 2013-04-02 2016-08-02 Syngenta Participations Ag Insecticidal compounds
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EP0739344A1 (en) 1996-10-30
DE69505946T2 (de) 1999-04-15
AU684334B2 (en) 1997-12-11
JPH09500909A (ja) 1997-01-28
US5801023A (en) 1998-09-01
DE69505946D1 (de) 1998-12-17
ATE173264T1 (de) 1998-11-15
CA2181168A1 (en) 1995-07-20
WO1995019363A1 (en) 1995-07-20
JP2767161B2 (ja) 1998-06-18
EP0739344B1 (en) 1998-11-11
AU1424895A (en) 1995-08-01
NZ278143A (en) 1997-11-24
CA2181168C (en) 2000-05-09

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