SK288128B6 - Process for purifying immunoglobulin G (IgG), liquid immunoglobulin product and use thereof for the preparation of a medicament - Google Patents
Process for purifying immunoglobulin G (IgG), liquid immunoglobulin product and use thereof for the preparation of a medicament Download PDFInfo
- Publication number
- SK288128B6 SK288128B6 SK1866-2000A SK18662000A SK288128B6 SK 288128 B6 SK288128 B6 SK 288128B6 SK 18662000 A SK18662000 A SK 18662000A SK 288128 B6 SK288128 B6 SK 288128B6
- Authority
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- Slovakia
- Prior art keywords
- immunoglobulin
- igg
- exchange resin
- product
- buffer
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98201909 | 1998-06-09 | ||
| US10205598P | 1998-09-28 | 1998-09-28 | |
| PCT/DK1999/000312 WO1999064462A1 (en) | 1998-06-09 | 1999-06-09 | Process for producing immunoglobulins for intravenous administration and other immunoglobulin products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK18662000A3 SK18662000A3 (sk) | 2001-07-10 |
| SK288128B6 true SK288128B6 (sk) | 2013-10-02 |
Family
ID=26150417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1866-2000A SK288128B6 (sk) | 1998-06-09 | 1999-06-09 | Process for purifying immunoglobulin G (IgG), liquid immunoglobulin product and use thereof for the preparation of a medicament |
Country Status (22)
| Country | Link |
|---|---|
| EP (4) | EP1493751A1 (cs) |
| JP (1) | JP5478519B2 (cs) |
| KR (1) | KR100501263B1 (cs) |
| CN (1) | CN1196714C (cs) |
| AT (1) | ATE277950T1 (cs) |
| AU (1) | AU753468B2 (cs) |
| BR (1) | BR9911131A (cs) |
| CA (1) | CA2330170C (cs) |
| CZ (1) | CZ297199B6 (cs) |
| DE (1) | DE69920693T2 (cs) |
| DK (1) | DK1084147T3 (cs) |
| ES (1) | ES2229784T3 (cs) |
| HU (1) | HU228076B1 (cs) |
| ID (1) | ID27417A (cs) |
| IL (1) | IL140155A (cs) |
| NZ (1) | NZ509135A (cs) |
| PL (1) | PL196770B1 (cs) |
| PT (1) | PT1084147E (cs) |
| RU (1) | RU2197500C2 (cs) |
| SK (1) | SK288128B6 (cs) |
| TR (1) | TR200100303T2 (cs) |
| WO (1) | WO1999064462A1 (cs) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2158776B1 (es) * | 1999-04-13 | 2002-03-16 | Apc Europ S A | Procedimiento para la obtencion de gammaglobulinas de origen animal y aplicaciones correspondientes. |
| AUPQ026799A0 (en) * | 1999-05-10 | 1999-06-03 | Csl Limited | Method of increasing protein stability by removing immunoglobulin aggregates |
| CA2400504A1 (en) * | 2000-03-10 | 2001-09-13 | Egil Lien | Composition for the treatment of heart failure |
| SE0001128D0 (sv) | 2000-03-30 | 2000-03-30 | Amersham Pharm Biotech Ab | A method of producing IgG |
| ES2184594B1 (es) * | 2001-01-17 | 2004-01-01 | Probitas Pharma Sa | Procedimiento para la produccion de gammaglobulina g humana inactivada de virus. |
| FR2824568B1 (fr) | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| US20030223985A1 (en) * | 2002-05-29 | 2003-12-04 | The Lauridsen Group. Incorporated | Globulin protein to lower cholesterol in humans |
| WO2004024752A1 (ja) | 2002-09-11 | 2004-03-25 | Chugai Seiyaku Kabushiki Kaisha | タンパク質精製方法 |
| EP1614693A4 (en) * | 2003-03-31 | 2006-07-19 | Kirin Brewery | Purification of a human monoclonal antibody and human polyclonal antibody |
| EP1532983A1 (en) | 2003-11-18 | 2005-05-25 | ZLB Bioplasma AG | Immunoglobulin preparations having increased stability |
| JP2008500959A (ja) * | 2004-01-30 | 2008-01-17 | スオメン プナイネン リスティ ヴェリパルヴェル | ウイルスについて安全な免疫グロブリンの製造方法 |
| EP2532742B1 (en) | 2004-01-30 | 2018-08-08 | Shire Pharmaceuticals Ireland Limited | Recombinant arylsulfatase A for reducing galatosyl sulphatide levels in a subject |
| RU2252780C1 (ru) * | 2004-04-30 | 2005-05-27 | Аваков Анатолий Эдуардович | Способ получения иммуноглобулинового препарата |
| AU2005229674B2 (en) * | 2004-11-18 | 2010-11-04 | Kedrion Melville Inc. | Low concentration solvent/detergent process of immuneglobulin with pre-treatment |
| TWI391399B (zh) | 2005-05-25 | 2013-04-01 | Hoffmann La Roche | 測定溶離多肽之鹽濃度之方法 |
| KR101363777B1 (ko) | 2005-09-30 | 2014-02-14 | 메디뮨 리미티드 | 인터루킨―１３ 항체 조성물 |
| US9309316B2 (en) | 2005-12-20 | 2016-04-12 | Bristol-Myers Squibb Company | Stable subcutaneous protein formulations and uses thereof |
| FR2895263B1 (fr) | 2005-12-26 | 2008-05-30 | Lab Francais Du Fractionnement | Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives |
| ES2744499T3 (es) | 2006-04-04 | 2020-02-25 | Chiesi Farm Spa | Un proceso para la concentración de un polipéptido |
| RU2303995C1 (ru) * | 2006-04-28 | 2007-08-10 | Халлар Абдумуслимович Алиханов | Средство, обладающее иммунорегуляторным свойством и его применение для лечения аутоиммунных заболеваний |
| WO2008025748A1 (en) | 2006-08-28 | 2008-03-06 | Ares Trading S.A. | Process for the purification of fc-containing proteins |
| DE102007001521A1 (de) * | 2007-01-10 | 2008-07-17 | Matthias, Torsten, Dr. | Verwendung von Cohn-Oncley-Fraktionen II und II/III zur Behandlung des systemischen Lupus erythematodes |
| UA85734C2 (ru) * | 2007-02-14 | 2009-02-25 | Костянтин Васильевич Курищук | Способ инактивации вирусов при получении иммуноглобулина |
| UA85741C2 (ru) * | 2007-02-27 | 2009-02-25 | Костянтин Васильевич Курищук | Способ получения иммуноглобулина |
| RU2352358C1 (ru) * | 2007-10-04 | 2009-04-20 | Наталия Васильевна Зубкова | Способ приготовления вирусинактивированных растворов иммуноглобулинов |
| PL2215117T5 (pl) | 2007-10-30 | 2018-06-29 | Genentech, Inc. | Oczyszczanie przeciwciał za pomocą chromatografii kationowymiennej |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| EP2271382B1 (en) | 2008-04-15 | 2013-03-13 | Grifols Therapeutics Inc. | Two-stage ultrafiltration/diafiltration |
| RU2410395C2 (ru) * | 2008-05-04 | 2011-01-27 | Институт биохимии и физиологии растений и микроорганизмов Российской Академии наук | Способ получения моноспецифических антител к белкам растительных клеток |
| FR2939667B1 (fr) | 2008-12-17 | 2012-01-27 | Fractionnement Et Des Biotechonologies Lab Franc | Composition d'immunoglobine g comme medicament pour le traitement de l'ictere neonatal par incompatibilite foetomaternelle dans le systeme abo |
| BRPI1012082B1 (pt) | 2009-05-27 | 2022-08-16 | Takeda Pharmaceutical Company Limited | Método para preparar uma composição de igg concentrada a partir de plasma |
| EP2519537A4 (en) * | 2009-12-29 | 2013-07-10 | Reddys Lab Ltd Dr | CLEANING PROTEINS |
| JP6078344B2 (ja) | 2010-02-04 | 2017-02-08 | ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト | 免疫グロブリン製剤 |
| EP2361636A1 (en) * | 2010-02-26 | 2011-08-31 | CSL Behring AG | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
| GB201006753D0 (en) | 2010-04-22 | 2010-06-09 | Biotest Ag | Process for preparing an immunolobulin composition |
| RU2467783C2 (ru) * | 2010-07-30 | 2012-11-27 | Закрытое акционерное общество "БиоХимМак СТ" | Способ хроматографического выделения иммуноглобулина |
| ES2811526T3 (es) | 2010-12-30 | 2021-03-12 | Lab Francais Du Fractionnement | Glicoles como agentes de inactivación de patógenos |
| PL2686334T5 (pl) | 2011-03-16 | 2020-10-19 | F.Hoffmann-La Roche Ag | Chromatografia jonowymienna o ulepszonej selektywności do rozdzielania monomerów, agregatów i fragmentów polipeptydowych przez modulację fazy ruchomej |
| FR2974301B1 (fr) | 2011-04-20 | 2013-08-23 | Lab Francais Du Fractionnement | Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes |
| IL212911A0 (en) * | 2011-05-16 | 2011-07-31 | Omrix Biopharmaceuticals Ltd | Immunoglobulin reduced in thrombogenic contaminants and preparation thereof |
| EP2729566B1 (en) | 2011-07-08 | 2017-03-15 | Shire Human Genetic Therapies, Inc. | Methods for purification of arylsulfatase a |
| CN103874708B (zh) * | 2011-08-26 | 2018-07-10 | 百深有限责任公司 | 用于降低血浆来源免疫球蛋白组合物的血栓栓塞可能性的方法 |
| CN102532307B (zh) * | 2012-02-22 | 2013-06-12 | 成都蓉生药业有限责任公司 | 一种制备人免疫球蛋白的方法 |
| DK3590960T3 (da) | 2012-02-29 | 2023-04-24 | Takeda Pharmaceuticals Co | Igg-stimuleret remyelinisering af perifere nerver |
| EP2822967B1 (en) | 2012-03-09 | 2019-08-07 | CSL Behring AG | Compositions comprising secretory-like immunoglobulins |
| EP2636681A1 (en) | 2012-03-09 | 2013-09-11 | CSL Behring AG | Process for enriching IgA |
| EP2636684A1 (en) | 2012-03-09 | 2013-09-11 | CSL Behring AG | Prevention of infection |
| ES2381828B1 (es) * | 2012-03-20 | 2012-11-16 | Grifols, S.A. | PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO |
| CN104507955A (zh) * | 2012-05-31 | 2015-04-08 | 新加坡科技研究局 | 采用具有多形式官能性的颗粒对免疫球蛋白g制备物的色谱纯化 |
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| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
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| CN106999588A (zh) | 2014-12-03 | 2017-08-01 | 瑞士杰特贝林生物制品有限公司 | 具有增加的稳定性的包含免疫球蛋白的药物产品 |
| FR3035971A1 (fr) | 2015-05-07 | 2016-11-11 | Lab Francais Du Fractionnement | Composition enrichie en immunoglobulines polyclonales anti-a et/ou anti-b |
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| CN105950576A (zh) * | 2016-05-26 | 2016-09-21 | 成都远睿生物技术有限公司 | 一种从牛血中提取多种蛋白的方法 |
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| CN107880116B (zh) * | 2016-09-30 | 2023-02-03 | 盖立复集团公司 | 用于制备免疫球蛋白的方法 |
| FR3064484A1 (fr) | 2017-03-31 | 2018-10-05 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Composition d'immunoglobulines utiles pour traiter des infections virales |
| FR3064486A1 (fr) | 2017-03-31 | 2018-10-05 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Prevention d'une infection par le virus respiratoire syncytial dans les voies respiratoires superieures |
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| DE2364792A1 (de) * | 1973-01-15 | 1974-07-18 | South African Inventions | Verfahren zum reinigen von gammaglobulin |
| US4296027A (en) * | 1977-08-31 | 1981-10-20 | The Regents Of The University Of Minnesota | Pure intravenous human and animal gamma globulins |
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| US4606825A (en) * | 1985-04-22 | 1986-08-19 | J. T. Baker Chemical Company | Purification of immunoglobulin G |
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