SK285675B6 - Nitrilová zlúčenina a spôsob výroby chinolínovéhoderivátu - Google Patents
Nitrilová zlúčenina a spôsob výroby chinolínovéhoderivátu Download PDFInfo
- Publication number
- SK285675B6 SK285675B6 SK62-2001A SK622001A SK285675B6 SK 285675 B6 SK285675 B6 SK 285675B6 SK 622001 A SK622001 A SK 622001A SK 285675 B6 SK285675 B6 SK 285675B6
- Authority
- SK
- Slovakia
- Prior art keywords
- mixture
- temperature
- formula
- solution
- stirred
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20791198 | 1998-07-23 | ||
| PCT/JP1999/003923 WO2000005213A1 (fr) | 1998-07-23 | 1999-07-22 | Procede de preparation d'un derive de quinoleine et produit intermediaire pour ce procede |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK622001A3 SK622001A3 (en) | 2001-08-06 |
| SK285675B6 true SK285675B6 (sk) | 2007-06-07 |
Family
ID=16547618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK62-2001A SK285675B6 (sk) | 1998-07-23 | 1999-07-22 | Nitrilová zlúčenina a spôsob výroby chinolínovéhoderivátu |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6335449B1 (pt) |
| EP (1) | EP1099694B1 (pt) |
| JP (1) | JP4281248B2 (pt) |
| KR (1) | KR100529201B1 (pt) |
| CN (1) | CN1107670C (pt) |
| AT (1) | ATE302190T1 (pt) |
| AU (1) | AU746722C (pt) |
| CA (1) | CA2338334C (pt) |
| CZ (1) | CZ299881B6 (pt) |
| DE (1) | DE69926760T2 (pt) |
| DK (1) | DK1099694T3 (pt) |
| ES (1) | ES2247813T3 (pt) |
| IL (2) | IL140924A0 (pt) |
| MX (1) | MXPA01000890A (pt) |
| NO (1) | NO317787B1 (pt) |
| NZ (1) | NZ509401A (pt) |
| PT (1) | PT1099694E (pt) |
| RU (1) | RU2214402C2 (pt) |
| SK (1) | SK285675B6 (pt) |
| WO (1) | WO2000005213A1 (pt) |
| ZA (1) | ZA200100525B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4496586B2 (ja) * | 2000-01-24 | 2010-07-07 | 日産化学工業株式会社 | キノリルアクリロニトリルの製造法及びその中間体 |
| JP4496585B2 (ja) * | 2000-01-24 | 2010-07-07 | 日産化学工業株式会社 | キノリルプロペナールの製造方法 |
| ATE366239T1 (de) * | 2000-01-24 | 2007-07-15 | Nissan Chemical Ind Ltd | Verfahren zur herstellung von quinolylpropenal |
| JP4496584B2 (ja) * | 2000-01-24 | 2010-07-07 | 日産化学工業株式会社 | キノリルプロペナールの製造法 |
| JP4867071B2 (ja) * | 2000-02-21 | 2012-02-01 | 日産化学工業株式会社 | キノリン誘導体の製造方法 |
| WO2001060800A1 (fr) * | 2000-02-21 | 2001-08-23 | Kuraray Co., Ltd. | Procedes de preparation de derives de quinoline et de leurs intermediaires |
| HUP0303353A3 (en) * | 2000-10-12 | 2004-10-28 | Kowa Co | Preventives and remedies for complications of diabetes |
| JP2002155056A (ja) * | 2000-11-17 | 2002-05-28 | Ube Ind Ltd | キノリルアクリロニトリル誘導体の製法 |
| TWI309644B (pt) * | 2001-02-14 | 2009-05-11 | Nissan Chemical Ind Ltd | |
| JP4590749B2 (ja) * | 2001-02-14 | 2010-12-01 | 宇部興産株式会社 | キノリンカルボキシアルデヒド誘導体の製法 |
| KR20040026705A (ko) | 2001-08-16 | 2004-03-31 | 테바 파마슈티컬 인더스트리즈 리미티드 | 스타틴의 칼슘 염 형태의 제조 방법 |
| CA2513837A1 (en) | 2003-02-12 | 2004-08-26 | Paul Adriaan Van Der Schaaf | Crystalline forms of pitavastatin calcium |
| SI2024341T1 (sl) | 2006-05-03 | 2016-04-29 | Msn Laboratories Private Limited | Novi postopek za statine in njihove farmacevtsko sprejemljive soli |
| EP2086945B1 (en) | 2006-10-09 | 2016-01-06 | MSN Laboratories Private Limited | Novel process for the preparation of statins and their pharmaceutically acceptable salts thereof |
| WO2010089770A2 (en) | 2009-01-19 | 2010-08-12 | Msn Laboratories Limited | Improved process for the preparation of highly pure (3r,5s)-7-[2-cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxy-6(e)-heptenoic acid and pharmaceutically acceptable salts thereof |
| WO2011086584A2 (en) | 2010-01-18 | 2011-07-21 | Msn Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
| WO2011089623A2 (en) | 2010-01-20 | 2011-07-28 | Cadila Healthcare Limited | Process for preparing pitavastatin and pharmaceutically acceptable salts thereof |
| JP2013536219A (ja) | 2010-08-25 | 2013-09-19 | カディラ・ヘルスケア・リミテッド | ピタバスタチンカルシウムおよびその調製方法 |
| CN103508949B (zh) * | 2013-10-22 | 2015-12-09 | 黄河三角洲京博化工研究院有限公司 | 一种（e）-3-[2-环丙基-4-（4-氟-苯基）-3-喹啉基]丙烯醛的合成方法 |
| WO2016005919A1 (en) | 2014-07-09 | 2016-01-14 | Lupin Limited | Polymorphic forms of pitavastatin sodium |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5815836A (ja) * | 1981-07-17 | 1983-01-29 | オリンパス光学工業株式会社 | 内視鏡管路の洗浄装置 |
| JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| US5854259A (en) | 1987-08-20 | 1998-12-29 | Nissan Chemical Industries Ltd. | Quinoline type mevalonolactones |
| US5185328A (en) | 1987-08-20 | 1993-02-09 | Nissan Chemical Industries Ltd. | Quinoline type mevalonolactones useful for treating hyperlipidemia, hyperlipoproteinemia or atherosclerosis |
| DE3905908A1 (de) * | 1989-02-25 | 1990-09-06 | Bayer Ag | Substituierte chinoline, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| JP3528186B2 (ja) | 1991-06-24 | 2004-05-17 | 日産化学工業株式会社 | 光学活性キノリンメバロン酸のジアステレオマー塩 |
| JP3130342B2 (ja) | 1991-10-04 | 2001-01-31 | 日産化学工業株式会社 | 動脈硬化性血管内膜肥厚抑制薬 |
| KR100355335B1 (ko) | 1994-02-25 | 2003-04-11 | 다이세루 가가꾸 고오교 가부시끼가이샤 | 광학활성메발로노락톤계화합물의제조방법 |
-
1999
- 1999-07-22 CN CN99809003A patent/CN1107670C/zh not_active Expired - Fee Related
- 1999-07-22 PT PT99931484T patent/PT1099694E/pt unknown
- 1999-07-22 JP JP2000561169A patent/JP4281248B2/ja not_active Expired - Fee Related
- 1999-07-22 MX MXPA01000890A patent/MXPA01000890A/es not_active IP Right Cessation
- 1999-07-22 DK DK99931484T patent/DK1099694T3/da active
- 1999-07-22 EP EP99931484A patent/EP1099694B1/en not_active Expired - Lifetime
- 1999-07-22 IL IL14092499A patent/IL140924A0/xx active IP Right Grant
- 1999-07-22 US US09/764,994 patent/US6335449B1/en not_active Expired - Lifetime
- 1999-07-22 CZ CZ20010062A patent/CZ299881B6/cs not_active IP Right Cessation
- 1999-07-22 CA CA002338334A patent/CA2338334C/en not_active Expired - Fee Related
- 1999-07-22 NZ NZ509401A patent/NZ509401A/xx not_active IP Right Cessation
- 1999-07-22 DE DE69926760T patent/DE69926760T2/de not_active Expired - Lifetime
- 1999-07-22 KR KR10-2001-7000778A patent/KR100529201B1/ko not_active IP Right Cessation
- 1999-07-22 RU RU2001105200/04A patent/RU2214402C2/ru not_active IP Right Cessation
- 1999-07-22 WO PCT/JP1999/003923 patent/WO2000005213A1/ja active IP Right Grant
- 1999-07-22 ES ES99931484T patent/ES2247813T3/es not_active Expired - Lifetime
- 1999-07-22 SK SK62-2001A patent/SK285675B6/sk not_active IP Right Cessation
- 1999-07-22 AU AU47992/99A patent/AU746722C/en not_active Ceased
- 1999-07-22 AT AT99931484T patent/ATE302190T1/de active
-
2001
- 2001-01-16 IL IL140924A patent/IL140924A/en not_active IP Right Cessation
- 2001-01-18 ZA ZA200100525A patent/ZA200100525B/en unknown
- 2001-01-22 NO NO20010357A patent/NO317787B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4799299A (en) | 2000-02-14 |
| CN1310711A (zh) | 2001-08-29 |
| DE69926760T2 (de) | 2006-01-19 |
| RU2214402C2 (ru) | 2003-10-20 |
| WO2000005213A1 (fr) | 2000-02-03 |
| NZ509401A (en) | 2002-08-28 |
| CA2338334C (en) | 2008-07-15 |
| NO317787B1 (no) | 2004-12-13 |
| IL140924A (en) | 2006-06-11 |
| NO20010357D0 (no) | 2001-01-22 |
| AU746722B2 (en) | 2002-05-02 |
| JP4281248B2 (ja) | 2009-06-17 |
| CN1107670C (zh) | 2003-05-07 |
| CA2338334A1 (en) | 2000-02-03 |
| KR100529201B1 (ko) | 2005-11-17 |
| ZA200100525B (en) | 2001-08-01 |
| EP1099694B1 (en) | 2005-08-17 |
| AU746722C (en) | 2003-03-27 |
| DE69926760D1 (de) | 2005-09-22 |
| US6335449B1 (en) | 2002-01-01 |
| CZ200162A3 (en) | 2001-06-13 |
| DK1099694T3 (da) | 2005-09-19 |
| ES2247813T3 (es) | 2006-03-01 |
| PT1099694E (pt) | 2005-10-31 |
| MXPA01000890A (es) | 2002-06-04 |
| CZ299881B6 (cs) | 2008-12-17 |
| IL140924A0 (en) | 2002-02-10 |
| KR20010070987A (ko) | 2001-07-28 |
| NO20010357L (no) | 2001-01-22 |
| SK622001A3 (en) | 2001-08-06 |
| EP1099694A1 (en) | 2001-05-16 |
| EP1099694A4 (en) | 2002-08-14 |
| ATE302190T1 (de) | 2005-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20150722 |