ATE366239T1 - Verfahren zur herstellung von quinolylpropenal - Google Patents
Verfahren zur herstellung von quinolylpropenalInfo
- Publication number
- ATE366239T1 ATE366239T1 AT01901538T AT01901538T ATE366239T1 AT E366239 T1 ATE366239 T1 AT E366239T1 AT 01901538 T AT01901538 T AT 01901538T AT 01901538 T AT01901538 T AT 01901538T AT E366239 T1 ATE366239 T1 AT E366239T1
- Authority
- AT
- Austria
- Prior art keywords
- quinolyl
- propenal
- producing
- formic acid
- fluorophenyl
- Prior art date
Links
- HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 6
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 3
- 235000019253 formic acid Nutrition 0.000 abstract 3
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- -1 amine salt Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000014848A JP4496584B2 (ja) | 2000-01-24 | 2000-01-24 | キノリルプロペナールの製造法 |
| JP2000014849A JP4496585B2 (ja) | 2000-01-24 | 2000-01-24 | キノリルプロペナールの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE366239T1 true ATE366239T1 (de) | 2007-07-15 |
Family
ID=26584043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01901538T ATE366239T1 (de) | 2000-01-24 | 2001-01-24 | Verfahren zur herstellung von quinolylpropenal |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6630591B2 (de) |
| EP (1) | EP1251124B1 (de) |
| CN (1) | CN1222512C (de) |
| AT (1) | ATE366239T1 (de) |
| AU (1) | AU2001227100A1 (de) |
| CA (1) | CA2398138C (de) |
| DE (1) | DE60129203T2 (de) |
| WO (1) | WO2001053265A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2423195A1 (de) * | 2010-07-26 | 2012-02-29 | LEK Pharmaceuticals d.d. | Verfahren zur Herstellung von wesentlichen Zwischenstufen zur Synthese von Rosuvastatin oder pharmazeutisch annehmbaren Salzen davon |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| JP3130342B2 (ja) * | 1991-10-04 | 2001-01-31 | 日産化学工業株式会社 | 動脈硬化性血管内膜肥厚抑制薬 |
| NZ509401A (en) * | 1998-07-23 | 2002-08-28 | Nissan Chemical Ind Ltd | Process for the preparation of quinoline derivative using the intermediate 2-cyclopropyl-3-(3-cyano-prop-2-ene)-4-(4-fluorophenyl)-quinoline |
-
2001
- 2001-01-24 EP EP01901538A patent/EP1251124B1/de not_active Expired - Lifetime
- 2001-01-24 CN CN01807062.0A patent/CN1222512C/zh not_active Expired - Fee Related
- 2001-01-24 CA CA002398138A patent/CA2398138C/en not_active Expired - Fee Related
- 2001-01-24 US US10/181,820 patent/US6630591B2/en not_active Expired - Lifetime
- 2001-01-24 AT AT01901538T patent/ATE366239T1/de not_active IP Right Cessation
- 2001-01-24 AU AU2001227100A patent/AU2001227100A1/en not_active Abandoned
- 2001-01-24 DE DE60129203T patent/DE60129203T2/de not_active Expired - Lifetime
- 2001-01-24 WO PCT/JP2001/000452 patent/WO2001053265A1/ja active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1251124A1 (de) | 2002-10-23 |
| CA2398138A1 (en) | 2001-07-26 |
| DE60129203D1 (de) | 2007-08-16 |
| CN1419544A (zh) | 2003-05-21 |
| CA2398138C (en) | 2009-12-22 |
| EP1251124B1 (de) | 2007-07-04 |
| CN1222512C (zh) | 2005-10-12 |
| DE60129203T2 (de) | 2008-03-13 |
| WO2001053265A1 (fr) | 2001-07-26 |
| EP1251124A4 (de) | 2004-09-01 |
| US6630591B2 (en) | 2003-10-07 |
| AU2001227100A1 (en) | 2001-07-31 |
| US20030114680A1 (en) | 2003-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |