SK14962001A3 - Farmaceutický prípravok obsahujúci inhibítor trombínu s nízkou molekulovou hmotnosťou a jeho prekurzor - Google Patents

Farmaceutický prípravok obsahujúci inhibítor trombínu s nízkou molekulovou hmotnosťou a jeho prekurzor Download PDF

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Publication number
SK14962001A3
SK14962001A3 SK1496-2001A SK14962001A SK14962001A3 SK 14962001 A3 SK14962001 A3 SK 14962001A3 SK 14962001 A SK14962001 A SK 14962001A SK 14962001 A3 SK14962001 A3 SK 14962001A3
Authority
SK
Slovakia
Prior art keywords
pharmaceutically acceptable
thrombin inhibitor
component
molecular weight
low molecular
Prior art date
Application number
SK1496-2001A
Other languages
English (en)
Slovak (sk)
Inventor
David Gustafsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901442A external-priority patent/SE523811C2/sv
Priority claimed from SE9904419A external-priority patent/SE9904419D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SK14962001A3 publication Critical patent/SK14962001A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SK1496-2001A 1999-04-21 2000-04-19 Farmaceutický prípravok obsahujúci inhibítor trombínu s nízkou molekulovou hmotnosťou a jeho prekurzor SK14962001A3 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9901442A SE523811C2 (sv) 1999-04-21 1999-04-21 Beredning innehållande en trombininhibitor med låg molekylvikt tillsammans med en prodrog av densamma
SE9904419A SE9904419D0 (sv) 1999-12-03 1999-12-03 New use
PCT/SE2000/000756 WO2000064470A1 (en) 1999-04-21 2000-04-19 A pharmaceutical formulation comprising a low molecular weight thrombin inhibitor and its prodrug

Publications (1)

Publication Number Publication Date
SK14962001A3 true SK14962001A3 (sk) 2002-06-04

Family

ID=26663557

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1496-2001A SK14962001A3 (sk) 1999-04-21 2000-04-19 Farmaceutický prípravok obsahujúci inhibítor trombínu s nízkou molekulovou hmotnosťou a jeho prekurzor

Country Status (29)

Country Link
US (3) US6962905B1 (enExample)
EP (2) EP1200118B1 (enExample)
JP (1) JP2002542298A (enExample)
KR (1) KR20010110788A (enExample)
CN (1) CN100377742C (enExample)
AR (1) AR023510A1 (enExample)
AT (1) ATE383868T1 (enExample)
AU (1) AU754405B2 (enExample)
BR (1) BR0009847A (enExample)
CA (1) CA2371008A1 (enExample)
CZ (1) CZ20013757A3 (enExample)
DE (1) DE60037816T2 (enExample)
DK (1) DK1200118T3 (enExample)
EE (1) EE200100543A (enExample)
ES (1) ES2298141T3 (enExample)
HK (1) HK1045465B (enExample)
HU (1) HUP0200955A3 (enExample)
IL (1) IL145840A0 (enExample)
IS (1) IS6111A (enExample)
MY (1) MY128061A (enExample)
NO (1) NO20015107L (enExample)
NZ (1) NZ514827A (enExample)
PL (1) PL201793B1 (enExample)
PT (1) PT1200118E (enExample)
RU (1) RU2252783C2 (enExample)
SA (1) SA00210092B1 (enExample)
SK (1) SK14962001A3 (enExample)
TR (1) TR200103017T2 (enExample)
WO (1) WO2000064470A1 (enExample)

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AR023510A1 (es) * 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
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DE10301300B4 (de) 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
GB0306615D0 (en) * 2003-03-22 2003-04-30 Astrazeneca Ab New use
DE10342108A1 (de) * 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
DE102005044319A1 (de) 2005-09-16 2007-03-22 Curacyte Chemistry Gmbh 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
SG10201502484SA (en) 2010-03-30 2015-05-28 Verseon Corp Multisubstituted aromatic compounds as inhibitors of thrombin
ES2702182T3 (es) 2013-03-15 2019-02-27 Verseon Corp Compuestos aromáticos multisustituidos como inhibidores de la serina proteasa
HK1214252A1 (zh) 2013-03-15 2016-07-22 Verseon Corporation 作為凝血酶抑制劑的鹵代吡唑
BR112017004704A2 (pt) 2014-09-17 2018-01-23 Verseon Corp composto, composição farmacêutica, e, método para tratar uma doença ou distúrbio em um indivíduo
SG11201706411YA (en) 2015-02-27 2017-09-28 Verseon Corp Substituted pyrazole compounds as serine protease inhibitors

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Also Published As

Publication number Publication date
NO20015107D0 (no) 2001-10-19
ES2298141T3 (es) 2008-05-16
EE200100543A (et) 2003-02-17
EP1886691A3 (en) 2008-03-05
HUP0200955A3 (en) 2006-07-28
DE60037816T2 (de) 2009-01-08
WO2000064470A1 (en) 2000-11-02
US6962905B1 (en) 2005-11-08
PT1200118E (pt) 2008-03-18
DK1200118T3 (da) 2008-04-21
US20060009397A1 (en) 2006-01-12
EP1200118B1 (en) 2008-01-16
PL201793B1 (pl) 2009-05-29
CZ20013757A3 (cs) 2002-05-15
CA2371008A1 (en) 2000-11-02
KR20010110788A (ko) 2001-12-13
CN100377742C (zh) 2008-04-02
RU2252783C2 (ru) 2005-05-27
HUP0200955A2 (en) 2002-09-28
NZ514827A (en) 2005-01-28
ATE383868T1 (de) 2008-02-15
AU4633600A (en) 2000-11-10
US20080113960A1 (en) 2008-05-15
PL351917A1 (en) 2003-06-30
BR0009847A (pt) 2002-01-08
NO20015107L (no) 2001-10-19
AR023510A1 (es) 2002-09-04
HK1045465A1 (en) 2002-11-29
SA00210092B1 (ar) 2006-11-11
HK1045465B (en) 2008-08-01
EP1200118A1 (en) 2002-05-02
IS6111A (is) 2001-10-19
JP2002542298A (ja) 2002-12-10
AU754405B2 (en) 2002-11-14
MY128061A (en) 2007-01-31
DE60037816D1 (de) 2008-03-06
TR200103017T2 (tr) 2002-05-21
CN1356908A (zh) 2002-07-03
EP1886691A2 (en) 2008-02-13
IL145840A0 (en) 2002-07-25

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