TR200103017T2 - Düşük molekül ağırlıklı trombin önleyici içeren formülasyon - Google Patents

Düşük molekül ağırlıklı trombin önleyici içeren formülasyon

Info

Publication number
TR200103017T2
TR200103017T2 TR2001/03017T TR200103017T TR200103017T2 TR 200103017 T2 TR200103017 T2 TR 200103017T2 TR 2001/03017 T TR2001/03017 T TR 2001/03017T TR 200103017 T TR200103017 T TR 200103017T TR 200103017 T2 TR200103017 T2 TR 200103017T2
Authority
TR
Turkey
Prior art keywords
molecular weight
low molecular
formulation
thrombin inhibitor
weight thrombin
Prior art date
Application number
TR2001/03017T
Other languages
English (en)
Turkish (tr)
Inventor
Gustafsson David
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901442A external-priority patent/SE523811C2/sv
Priority claimed from SE9904419A external-priority patent/SE9904419D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200103017T2 publication Critical patent/TR200103017T2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
TR2001/03017T 1999-04-21 2000-04-19 Düşük molekül ağırlıklı trombin önleyici içeren formülasyon TR200103017T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9901442A SE523811C2 (sv) 1999-04-21 1999-04-21 Beredning innehållande en trombininhibitor med låg molekylvikt tillsammans med en prodrog av densamma
SE9904419A SE9904419D0 (sv) 1999-12-03 1999-12-03 New use

Publications (1)

Publication Number Publication Date
TR200103017T2 true TR200103017T2 (tr) 2002-05-21

Family

ID=26663557

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03017T TR200103017T2 (tr) 1999-04-21 2000-04-19 Düşük molekül ağırlıklı trombin önleyici içeren formülasyon

Country Status (29)

Country Link
US (3) US6962905B1 (xx)
EP (2) EP1886691A3 (xx)
JP (1) JP2002542298A (xx)
KR (1) KR20010110788A (xx)
CN (1) CN100377742C (xx)
AR (1) AR023510A1 (xx)
AT (1) ATE383868T1 (xx)
AU (1) AU754405B2 (xx)
BR (1) BR0009847A (xx)
CA (1) CA2371008A1 (xx)
CZ (1) CZ20013757A3 (xx)
DE (1) DE60037816T2 (xx)
DK (1) DK1200118T3 (xx)
EE (1) EE200100543A (xx)
ES (1) ES2298141T3 (xx)
HK (1) HK1045465B (xx)
HU (1) HUP0200955A3 (xx)
IL (1) IL145840A0 (xx)
IS (1) IS6111A (xx)
MY (1) MY128061A (xx)
NO (1) NO20015107L (xx)
NZ (1) NZ514827A (xx)
PL (1) PL201793B1 (xx)
PT (1) PT1200118E (xx)
RU (1) RU2252783C2 (xx)
SA (1) SA00210092B1 (xx)
SK (1) SK14962001A3 (xx)
TR (1) TR200103017T2 (xx)
WO (1) WO2000064470A1 (xx)

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SE9900070D0 (sv) 1999-01-13 1999-01-13 Astra Ab New use
AR023510A1 (es) * 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
US20020116222A1 (en) * 2000-10-22 2002-08-22 Standing Stone, Inc. Method and system for administering anticoagulation therapy
US6462021B1 (en) * 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
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SE0103590D0 (sv) 2001-10-26 2001-10-26 Astrazeneca Ab New Combination
DK1485345T3 (da) 2002-03-11 2008-11-03 Curacyte Ag Urokinaseinhibitorer, deres fremstilling og anvendelse
SE0203349D0 (sv) * 2002-11-12 2002-11-12 Astrazeneca Ab New use
DE10301300B4 (de) 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
GB0306615D0 (en) * 2003-03-22 2003-04-30 Astrazeneca Ab New use
DE10342108A1 (de) * 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
DE102005044319A1 (de) 2005-09-16 2007-03-22 Curacyte Chemistry Gmbh 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
RU2639876C2 (ru) 2010-03-30 2017-12-25 Версеон Корпорейшн Мультизамещенные ароматические соединения в качестве ингибиторов тромбина
RU2019101889A (ru) 2013-03-15 2019-03-28 Версеон Корпорейшн Полизамещенные ароматические соединения в качестве ингибиторов сериновых протеаз
CN105209440B (zh) 2013-03-15 2019-07-23 维颂公司 作为凝血酶抑制剂的卤代吡唑
CN106687445A (zh) 2014-09-17 2017-05-17 维颂公司 作为丝氨酸蛋白酶抑制剂的吡唑基取代的吡啶酮化合物
EP3261639B1 (en) 2015-02-27 2022-08-24 Verseon International Corporation Substituted pyrazole compounds as serine protease inhibitors

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Also Published As

Publication number Publication date
IS6111A (is) 2001-10-19
CN100377742C (zh) 2008-04-02
US6962905B1 (en) 2005-11-08
DK1200118T3 (da) 2008-04-21
JP2002542298A (ja) 2002-12-10
DE60037816D1 (de) 2008-03-06
EP1200118A1 (en) 2002-05-02
NO20015107D0 (no) 2001-10-19
AU4633600A (en) 2000-11-10
PT1200118E (pt) 2008-03-18
EP1200118B1 (en) 2008-01-16
KR20010110788A (ko) 2001-12-13
IL145840A0 (en) 2002-07-25
WO2000064470A1 (en) 2000-11-02
AR023510A1 (es) 2002-09-04
EP1886691A3 (en) 2008-03-05
US20080113960A1 (en) 2008-05-15
SK14962001A3 (sk) 2002-06-04
EE200100543A (et) 2003-02-17
PL351917A1 (en) 2003-06-30
AU754405B2 (en) 2002-11-14
CN1356908A (zh) 2002-07-03
HUP0200955A2 (en) 2002-09-28
ES2298141T3 (es) 2008-05-16
RU2252783C2 (ru) 2005-05-27
BR0009847A (pt) 2002-01-08
NZ514827A (en) 2005-01-28
MY128061A (en) 2007-01-31
EP1886691A2 (en) 2008-02-13
HK1045465B (zh) 2008-08-01
HUP0200955A3 (en) 2006-07-28
CA2371008A1 (en) 2000-11-02
NO20015107L (no) 2001-10-19
CZ20013757A3 (cs) 2002-05-15
DE60037816T2 (de) 2009-01-08
HK1045465A1 (en) 2002-11-29
ATE383868T1 (de) 2008-02-15
PL201793B1 (pl) 2009-05-29
SA00210092B1 (ar) 2006-11-11
US20060009397A1 (en) 2006-01-12

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