IS6111A - Lyfjablanda sem felur í sér þrombínhemil með lágan mólmassa og forlyf hans - Google Patents

Lyfjablanda sem felur í sér þrombínhemil með lágan mólmassa og forlyf hans

Info

Publication number
IS6111A
IS6111A IS6111A IS6111A IS6111A IS 6111 A IS6111 A IS 6111A IS 6111 A IS6111 A IS 6111A IS 6111 A IS6111 A IS 6111A IS 6111 A IS6111 A IS 6111A
Authority
IS
Iceland
Prior art keywords
prodrug
molecular weight
pharmaceutical composition
low molecular
thrombin inhibitor
Prior art date
Application number
IS6111A
Other languages
English (en)
Inventor
Gustafsson David
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901442A external-priority patent/SE523811C2/sv
Priority claimed from SE9904419A external-priority patent/SE9904419D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS6111A publication Critical patent/IS6111A/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IS6111A 1999-04-21 2001-10-19 Lyfjablanda sem felur í sér þrombínhemil með lágan mólmassa og forlyf hans IS6111A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9901442A SE523811C2 (sv) 1999-04-21 1999-04-21 Beredning innehållande en trombininhibitor med låg molekylvikt tillsammans med en prodrog av densamma
SE9904419A SE9904419D0 (sv) 1999-12-03 1999-12-03 New use
PCT/SE2000/000756 WO2000064470A1 (en) 1999-04-21 2000-04-19 A pharmaceutical formulation comprising a low molecular weight thrombin inhibitor and its prodrug

Publications (1)

Publication Number Publication Date
IS6111A true IS6111A (is) 2001-10-19

Family

ID=26663557

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6111A IS6111A (is) 1999-04-21 2001-10-19 Lyfjablanda sem felur í sér þrombínhemil með lágan mólmassa og forlyf hans

Country Status (29)

Country Link
US (3) US6962905B1 (is)
EP (2) EP1200118B1 (is)
JP (1) JP2002542298A (is)
KR (1) KR20010110788A (is)
CN (1) CN100377742C (is)
AR (1) AR023510A1 (is)
AT (1) ATE383868T1 (is)
AU (1) AU754405B2 (is)
BR (1) BR0009847A (is)
CA (1) CA2371008A1 (is)
CZ (1) CZ20013757A3 (is)
DE (1) DE60037816T2 (is)
DK (1) DK1200118T3 (is)
EE (1) EE200100543A (is)
ES (1) ES2298141T3 (is)
HK (1) HK1045465B (is)
HU (1) HUP0200955A3 (is)
IL (1) IL145840A0 (is)
IS (1) IS6111A (is)
MY (1) MY128061A (is)
NO (1) NO20015107D0 (is)
NZ (1) NZ514827A (is)
PL (1) PL201793B1 (is)
PT (1) PT1200118E (is)
RU (1) RU2252783C2 (is)
SA (1) SA00210092B1 (is)
SK (1) SK14962001A3 (is)
TR (1) TR200103017T2 (is)
WO (1) WO2000064470A1 (is)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9900070D0 (sv) 1999-01-13 1999-01-13 Astra Ab New use
AR023510A1 (es) * 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
US20020116222A1 (en) * 2000-10-22 2002-08-22 Standing Stone, Inc. Method and system for administering anticoagulation therapy
US6462021B1 (en) * 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
SE0101762D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab New use
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
SE0103590D0 (sv) 2001-10-26 2001-10-26 Astrazeneca Ab New Combination
US7838560B2 (en) 2002-03-11 2010-11-23 The Medicines Company (Leipzig) Gmbh Urokinase inhibitors, production and use thereof
SE0203349D0 (sv) * 2002-11-12 2002-11-12 Astrazeneca Ab New use
DE10301300B4 (de) 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
GB0306615D0 (en) * 2003-03-22 2003-04-30 Astrazeneca Ab New use
DE10342108A1 (de) * 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
DE102005044319A1 (de) 2005-09-16 2007-03-22 Curacyte Chemistry Gmbh 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
CA2829790C (en) * 2010-03-30 2018-06-05 Verseon Corporation Multisubstituted aromatic compounds as inhibitors of thrombin
KR20150130405A (ko) 2013-03-15 2015-11-23 베르선 코포레이션 트롬빈의 억제제로서의 할로게노피라졸
PT2968297T (pt) 2013-03-15 2019-01-10 Verseon Corp Compostos aromáticos multissubstituídos como inibidores da serina protease
WO2016044662A1 (en) 2014-09-17 2016-03-24 Verseon Corporation Pyrazolyl-substituted pyridone compounds as serine protease inhibitors
ES2931460T3 (es) 2015-02-27 2022-12-29 Verseon Int Corporation Compuestos de pirazol sustituido como inhibidores de serina proteasa

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Also Published As

Publication number Publication date
HK1045465A1 (en) 2002-11-29
AU754405B2 (en) 2002-11-14
DK1200118T3 (da) 2008-04-21
HUP0200955A2 (en) 2002-09-28
CN100377742C (zh) 2008-04-02
BR0009847A (pt) 2002-01-08
EP1200118A1 (en) 2002-05-02
ES2298141T3 (es) 2008-05-16
EP1886691A3 (en) 2008-03-05
MY128061A (en) 2007-01-31
PL201793B1 (pl) 2009-05-29
JP2002542298A (ja) 2002-12-10
WO2000064470A1 (en) 2000-11-02
EP1886691A2 (en) 2008-02-13
PL351917A1 (en) 2003-06-30
SK14962001A3 (sk) 2002-06-04
KR20010110788A (ko) 2001-12-13
ATE383868T1 (de) 2008-02-15
EP1200118B1 (en) 2008-01-16
DE60037816T2 (de) 2009-01-08
SA00210092B1 (ar) 2006-11-11
EE200100543A (et) 2003-02-17
NO20015107L (no) 2001-10-19
US20080113960A1 (en) 2008-05-15
US6962905B1 (en) 2005-11-08
PT1200118E (pt) 2008-03-18
NZ514827A (en) 2005-01-28
AR023510A1 (es) 2002-09-04
HK1045465B (zh) 2008-08-01
CA2371008A1 (en) 2000-11-02
CN1356908A (zh) 2002-07-03
DE60037816D1 (de) 2008-03-06
CZ20013757A3 (cs) 2002-05-15
RU2252783C2 (ru) 2005-05-27
IL145840A0 (en) 2002-07-25
HUP0200955A3 (en) 2006-07-28
TR200103017T2 (tr) 2002-05-21
US20060009397A1 (en) 2006-01-12
AU4633600A (en) 2000-11-10
NO20015107D0 (no) 2001-10-19

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