AU2001255408A1 - Tetrahydro-azepinone derivatives as thrombin inhibitors - Google Patents
Tetrahydro-azepinone derivatives as thrombin inhibitorsInfo
- Publication number
- AU2001255408A1 AU2001255408A1 AU2001255408A AU5540801A AU2001255408A1 AU 2001255408 A1 AU2001255408 A1 AU 2001255408A1 AU 2001255408 A AU2001255408 A AU 2001255408A AU 5540801 A AU5540801 A AU 5540801A AU 2001255408 A1 AU2001255408 A1 AU 2001255408A1
- Authority
- AU
- Australia
- Prior art keywords
- tetrahydro
- thrombin inhibitors
- azepinone derivatives
- azepinone
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55009200A | 2000-04-14 | 2000-04-14 | |
US54909100A | 2000-04-14 | 2000-04-14 | |
US09550092 | 2000-04-14 | ||
US09549091 | 2000-04-14 | ||
US09/550,257 US6541467B1 (en) | 2000-04-14 | 2000-04-14 | Thrombin inhibitors having a lactam at P3 |
US09550257 | 2000-04-14 | ||
PCT/US2001/012337 WO2001079261A1 (en) | 2000-04-14 | 2001-04-13 | Tetrahydro-azepinone derivatives as thrombin inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001255408A1 true AU2001255408A1 (en) | 2001-10-30 |
Family
ID=27415549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001255408A Abandoned AU2001255408A1 (en) | 2000-04-14 | 2001-04-13 | Tetrahydro-azepinone derivatives as thrombin inhibitors |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2001255408A1 (en) |
WO (1) | WO2001079261A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6344450B1 (en) * | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
GB0127568D0 (en) * | 2001-11-16 | 2002-01-09 | Glaxo Group Ltd | Chemical compounds |
GB0228533D0 (en) * | 2002-12-06 | 2003-01-15 | Glaxo Group Ltd | Crystalline form |
WO2005007628A1 (en) | 2003-07-11 | 2005-01-27 | Bristol-Myers Squibb Company | Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
US9290485B2 (en) | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
CR20180413A (en) | 2016-02-05 | 2018-12-04 | Denali Therapeutics Inc | INHIBITORS OF PROTEIN QUINASA 1 THAT INTERACT WITH THE RECEIVER |
EP3552017B1 (en) | 2016-12-09 | 2022-02-23 | Denali Therapeutics Inc. | Compounds useful as ripk1 inhibitors |
AU2018360577A1 (en) | 2017-11-01 | 2020-06-18 | Bristol-Myers Squibb Company | Bridged bicyclic compounds as farnesoid X receptor modulators |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995035311A1 (en) * | 1994-06-17 | 1995-12-28 | Corvas International, Inc. | 3-amino-2-oxo-1-piperidineacetic derivatives as enzyme inhibitors |
JPH11508558A (en) * | 1995-06-27 | 1999-07-27 | メルク エンド カンパニー インコーポレーテッド | Pyridinone thrombin inhibitor |
NZ502803A (en) * | 1997-08-11 | 2001-11-30 | Cor Therapeutics Inc | Selective factor Xa inhibitors for treating diseases such as angina, myocardial infarction, transient ischemic attacks or diseases associated with undesired thrombosis |
EP0994894A1 (en) * | 1997-08-11 | 2000-04-26 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
WO1999007732A1 (en) * | 1997-08-11 | 1999-02-18 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
JP2002536437A (en) * | 1999-02-09 | 2002-10-29 | ブリストル−マイヤーズ スクイブ カンパニー | FXa lactam inhibitors and methods |
-
2001
- 2001-04-13 AU AU2001255408A patent/AU2001255408A1/en not_active Abandoned
- 2001-04-13 WO PCT/US2001/012337 patent/WO2001079261A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2001079261A1 (en) | 2001-10-25 |
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