AU6381701A - Bisamidino compounds as nhe-3 inhibitors - Google Patents
Bisamidino compounds as nhe-3 inhibitorsInfo
- Publication number
- AU6381701A AU6381701A AU63817/01A AU6381701A AU6381701A AU 6381701 A AU6381701 A AU 6381701A AU 63817/01 A AU63817/01 A AU 63817/01A AU 6381701 A AU6381701 A AU 6381701A AU 6381701 A AU6381701 A AU 6381701A
- Authority
- AU
- Australia
- Prior art keywords
- bisamidino
- nhe
- inhibitors
- compounds
- bisamidino compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10015248A DE10015248A1 (en) | 2000-03-28 | 2000-03-28 | Bisamidino compounds as NHE-3 inhibitors |
DE10015248 | 2000-03-28 | ||
PCT/EP2001/003474 WO2001072742A1 (en) | 2000-03-28 | 2001-03-27 | Bisamidino compounds as nhe-3 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU6381701A true AU6381701A (en) | 2001-10-08 |
Family
ID=7636604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU63817/01A Withdrawn AU6381701A (en) | 2000-03-28 | 2001-03-27 | Bisamidino compounds as nhe-3 inhibitors |
Country Status (4)
Country | Link |
---|---|
AR (1) | AR027734A1 (en) |
AU (1) | AU6381701A (en) |
DE (1) | DE10015248A1 (en) |
WO (1) | WO2001072742A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10163239A1 (en) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituted imidazolidines, process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them |
US20030187045A1 (en) | 2001-12-21 | 2003-10-02 | Uwe Heinelt | Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic |
US7049333B2 (en) | 2002-06-04 | 2006-05-23 | Sanofi-Aventis Deutschland Gmbh | Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis |
DE10304374A1 (en) | 2003-02-04 | 2004-08-05 | Aventis Pharma Deutschland Gmbh | Novel substituted 2-aminoimidazoles, process for their preparation, their use as medicament or diagnostic agent and medicament containing them |
US20050054705A1 (en) | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
DE10341240A1 (en) | 2003-09-08 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Substituted thienoimidazoles, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them |
EP1689732A4 (en) * | 2003-12-05 | 2008-10-22 | Univ North Carolina | Cationic substituted benzofurans as antimicrobial agents |
DE102005001411A1 (en) | 2005-01-12 | 2006-07-27 | Sanofi-Aventis Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, their use as medicament, and medicament containing them |
EP2170872B1 (en) | 2007-06-28 | 2010-09-01 | Sanofi-Aventis U.S. LLC | Process for the preparation of the n-(2-chloro-4-methyl-3-thienyl)-1h- benzimidazol-2-amine hydrochloride and intermediates thereof |
KR20110050718A (en) | 2008-09-02 | 2011-05-16 | 사노피-아벤티스 | Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof |
CN103819403B (en) | 2008-12-31 | 2017-01-04 | 阿德利克斯公司 | For treating the disease relevant with fluid retention or salt over loading and the Compounds and methods for of disorder of gastrointestinal tract |
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
AU2013304812B2 (en) | 2012-08-21 | 2016-06-09 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
KR20230132619A (en) | 2013-04-12 | 2023-09-15 | 알데릭스, 인코포레이티드 | Nhe3-binding compounds and methods for inhibiting phosphate transport |
SG11201700398RA (en) | 2014-07-25 | 2017-02-27 | Taisho Pharmaceutical Co Ltd | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
EP3565811A1 (en) | 2017-01-09 | 2019-11-13 | Ardelyx, Inc. | Inhibitors of nhe-mediated antiport |
AU2018205400B2 (en) | 2017-01-09 | 2022-07-14 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
BR112020002322A2 (en) | 2017-08-04 | 2020-09-01 | Ardelyx, Inc. | glycyrrhetinic acid derivatives for the treatment of hyperkalaemia |
AU2020218255A1 (en) | 2019-02-07 | 2021-09-09 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19633966A1 (en) * | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenyl-substituted alkenylcarboxylic acid guanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
US6011059A (en) * | 1997-12-24 | 2000-01-04 | Bristol-Myers Squibb Company | Acyl guanidine sodium/proton exchange inhibitors and method |
-
2000
- 2000-03-28 DE DE10015248A patent/DE10015248A1/en not_active Withdrawn
-
2001
- 2001-03-27 AU AU63817/01A patent/AU6381701A/en not_active Withdrawn
- 2001-03-27 WO PCT/EP2001/003474 patent/WO2001072742A1/en not_active Application Discontinuation
- 2001-03-28 AR ARP010101464A patent/AR027734A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE10015248A1 (en) | 2001-10-04 |
WO2001072742A1 (en) | 2001-10-04 |
AR027734A1 (en) | 2003-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK13 | Application withdrawn section 141(2)/reg 8.3(2) - pct appl. non-entering nat. phase, withdrawn by applicant |