SI9111599A - Postopek za pridobivanje vodotopnih analogov kamptotecina in intermediatov za njihovo pripravo, kot tudi spojine, ki jih dobimo s tem postopkom - Google Patents

Postopek za pridobivanje vodotopnih analogov kamptotecina in intermediatov za njihovo pripravo, kot tudi spojine, ki jih dobimo s tem postopkom Download PDF

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Publication number
SI9111599A
SI9111599A SI9111599A SI9111599A SI9111599A SI 9111599 A SI9111599 A SI 9111599A SI 9111599 A SI9111599 A SI 9111599A SI 9111599 A SI9111599 A SI 9111599A SI 9111599 A SI9111599 A SI 9111599A
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SI
Slovenia
Prior art keywords
compound
camptothecin
process according
formula
hydrogen
Prior art date
Application number
SI9111599A
Other languages
English (en)
Slovenian (sl)
Inventor
Joseph Marian Fortunak
Jeffery Lee Wood
Antonietta Rose Mastrocola
Mark Mellinger
Patrick Lee Burk
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of SI9111599A publication Critical patent/SI9111599A/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
SI9111599A 1990-09-28 1991-09-30 Postopek za pridobivanje vodotopnih analogov kamptotecina in intermediatov za njihovo pripravo, kot tudi spojine, ki jih dobimo s tem postopkom SI9111599A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58964390A 1990-09-28 1990-09-28
YU159991A YU159991A (sh) 1990-09-28 1991-09-30 Postupak za dobijanje u vodi rastvornih analoga kamptotecina i intermedijera za njihovu proizvodnju kao i jedinjenja dobijena ovim postupkom

Publications (1)

Publication Number Publication Date
SI9111599A true SI9111599A (sl) 1998-02-28

Family

ID=24358879

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9111599A SI9111599A (sl) 1990-09-28 1991-09-30 Postopek za pridobivanje vodotopnih analogov kamptotecina in intermediatov za njihovo pripravo, kot tudi spojine, ki jih dobimo s tem postopkom

Country Status (25)

Country Link
US (1) US5734056A (ja)
EP (1) EP0547165B1 (ja)
JP (1) JP2848958B2 (ja)
CN (1) CN1033509C (ja)
AT (1) ATE186461T1 (ja)
AU (1) AU664830B2 (ja)
CA (1) CA2090967C (ja)
CZ (1) CZ51593A3 (ja)
DE (1) DE69131775T2 (ja)
DK (1) DK0547165T3 (ja)
ES (1) ES2137932T3 (ja)
FI (1) FI931384A (ja)
GR (1) GR3031823T3 (ja)
HK (1) HK1012283A1 (ja)
HU (1) HUT70024A (ja)
IE (1) IE913402A1 (ja)
IL (1) IL99571A (ja)
NO (1) NO931153D0 (ja)
NZ (1) NZ239947A (ja)
PT (1) PT99109B (ja)
SI (1) SI9111599A (ja)
SK (1) SK283693B6 (ja)
WO (1) WO1992005785A1 (ja)
YU (1) YU159991A (ja)
ZA (1) ZA917748B (ja)

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US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
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US20080182990A1 (en) * 2004-08-09 2008-07-31 Shilpa Medicare Limited Process for the Preparation of Irinotecan Hydrochloride Trihydrate
NZ554677A (en) * 2004-11-05 2010-08-27 Samyang Corp Pharmaceutical formulation for increasing solubility of 10-hydroxycamptothecin compounds in non-aqueous polar solvents
US20060135546A1 (en) * 2004-12-16 2006-06-22 Jagadevappa Basavaraja Methods for the purification of 20(S)- camptothecin
JP5177429B2 (ja) * 2005-07-18 2013-04-03 バイパー サイエンシズ，インコーポレイティド 癌の治療
EP1943253A1 (en) * 2005-10-10 2008-07-16 Cipla Limited Novel crystalline forms
US7547785B2 (en) 2005-12-26 2009-06-16 Dr. Reddy's Laboratories Limited Process for preparing topotecan
WO2007127839A2 (en) * 2006-04-26 2007-11-08 The Regents Of The University Of California Compositions and methods for convection enhanced delivery of high molecular weight neurotherapeutics
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
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Also Published As

Publication number Publication date
PT99109A (pt) 1992-08-31
DE69131775T2 (de) 2000-04-20
ATE186461T1 (de) 1999-11-15
ZA917748B (en) 1992-09-30
HK1012283A1 (en) 1999-07-30
AU8739991A (en) 1992-04-28
DE69131775D1 (de) 1999-12-16
JP2848958B2 (ja) 1999-01-20
NO931153L (no) 1993-03-26
FI931384A0 (fi) 1993-03-26
CA2090967A1 (en) 1992-03-29
IL99571A0 (en) 1992-08-18
US5734056A (en) 1998-03-31
HUT70024A (en) 1995-09-28
DK0547165T3 (da) 2000-03-27
EP0547165B1 (en) 1999-11-10
WO1992005785A1 (en) 1992-04-16
SK283693B6 (sk) 2003-12-02
AU664830B2 (en) 1995-12-07
SK25993A3 (en) 1993-07-07
ES2137932T3 (es) 2000-01-01
EP0547165A1 (en) 1993-06-23
GR3031823T3 (en) 2000-02-29
PT99109B (pt) 1999-02-26
IE913402A1 (en) 1992-04-08
IL99571A (en) 2000-08-31
JPH06501476A (ja) 1994-02-17
CZ51593A3 (en) 1994-01-19
HU9300878D0 (en) 1993-06-28
YU159991A (sh) 1994-06-10
NZ239947A (en) 1994-07-26
CN1033509C (zh) 1996-12-11
CA2090967C (en) 2007-02-06
EP0547165A4 (ja) 1994-03-30
NO931153D0 (no) 1993-03-26
FI931384A (fi) 1993-03-26
CN1062731A (zh) 1992-07-15

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