SG11201903825SA - Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansion - Google Patents
Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansionInfo
- Publication number
- SG11201903825SA SG11201903825SA SG11201903825SA SG11201903825SA SG11201903825SA SG 11201903825S A SG11201903825S A SG 11201903825SA SG 11201903825S A SG11201903825S A SG 11201903825SA SG 11201903825S A SG11201903825S A SG 11201903825SA SG 11201903825S A SG11201903825S A SG 11201903825SA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- rule
- aapcs
- myeloid cell
- presenting cells
- Prior art date
Links
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 title abstract 5
- 210000000612 antigen-presenting cell Anatomy 0.000 title abstract 3
- 210000000066 myeloid cell Anatomy 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 239000013603 viral vector Substances 0.000 abstract 2
- 102000002627 4-1BB Ligand Human genes 0.000 abstract 1
- 108010082808 4-1BB Ligand Proteins 0.000 abstract 1
- 102000011786 HLA-A Antigens Human genes 0.000 abstract 1
- 108010075704 HLA-A Antigens Proteins 0.000 abstract 1
- 101001019455 Homo sapiens ICOS ligand Proteins 0.000 abstract 1
- 101001063392 Homo sapiens Lymphocyte function-associated antigen 3 Proteins 0.000 abstract 1
- 102100034980 ICOS ligand Human genes 0.000 abstract 1
- 102100030984 Lymphocyte function-associated antigen 3 Human genes 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229940126587 biotherapeutics Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0635—B lymphocytes
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70528—CD58
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- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
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- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662415274P | 2016-10-31 | 2016-10-31 | |
US201662438600P | 2016-12-23 | 2016-12-23 | |
US201762475053P | 2017-03-22 | 2017-03-22 | |
US201762481831P | 2017-04-05 | 2017-04-05 | |
PCT/US2017/059271 WO2018081789A1 (en) | 2016-10-31 | 2017-10-31 | Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansion |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201903825SA true SG11201903825SA (en) | 2019-05-30 |
Family
ID=60702946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201903825SA SG11201903825SA (en) | 2016-10-31 | 2017-10-31 | Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansion |
Country Status (14)
Country | Link |
---|---|
US (4) | US10415015B2 (de) |
EP (1) | EP3532608A1 (de) |
JP (2) | JP2019531744A (de) |
KR (2) | KR20190071802A (de) |
CN (2) | CN116478930A (de) |
AU (1) | AU2017347942A1 (de) |
BR (1) | BR112019008560A2 (de) |
CA (1) | CA3041673A1 (de) |
IL (1) | IL266221A (de) |
MA (1) | MA46668A (de) |
MX (2) | MX2019004708A (de) |
SG (1) | SG11201903825SA (de) |
TW (1) | TWI788307B (de) |
WO (1) | WO2018081789A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
EP3532607B1 (de) | 2016-10-26 | 2024-01-31 | Iovance Biotherapeutics, Inc. | Restimulierung von kryopräservierten tumor-infiltrierenden lymphozyten |
GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
US20200377855A1 (en) * | 2017-05-05 | 2020-12-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Rapid method for the culture of tumor infiltrating lymphocytes |
TW201919662A (zh) | 2017-06-05 | 2019-06-01 | 美商艾歐凡斯生物治療公司 | 對雙重難治性黑色素瘤使用腫瘤浸潤性淋巴細胞之方法 |
US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
BR112020018658A2 (pt) | 2018-03-15 | 2020-12-29 | KSQ Therapeutics, Inc. | Composições de regulação gênica e métodos para imu-noterapia aprimorada |
CN112368003A (zh) | 2018-04-27 | 2021-02-12 | 艾欧凡斯生物治疗公司 | 肿瘤浸润淋巴细胞的基因编辑及其在免疫治疗中的用途 |
TW202031273A (zh) * | 2018-08-31 | 2020-09-01 | 美商艾歐凡斯生物治療公司 | 抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療 |
WO2020081450A1 (en) | 2018-10-15 | 2020-04-23 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
TW202039830A (zh) * | 2018-11-05 | 2020-11-01 | 美商艾歐凡斯生物治療公司 | 用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途 |
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AU2017347942A1 (en) | 2019-05-30 |
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US10415015B2 (en) | 2019-09-17 |
BR112019008560A2 (pt) | 2019-09-17 |
CA3041673A1 (en) | 2018-05-03 |
MA46668A (fr) | 2019-09-04 |
US11667890B2 (en) | 2023-06-06 |
KR20190071802A (ko) | 2019-06-24 |
IL266221A (en) | 2019-06-30 |
JP2019531744A (ja) | 2019-11-07 |
US20190345445A1 (en) | 2019-11-14 |
KR20240013295A (ko) | 2024-01-30 |
TW201831690A (zh) | 2018-09-01 |
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