RU2765074C2 - Способ снятия напряжения в оболочках капсул для уменьшения предрасположенности к разлому - Google Patents
Способ снятия напряжения в оболочках капсул для уменьшения предрасположенности к разлому Download PDFInfo
- Publication number
- RU2765074C2 RU2765074C2 RU2019113369A RU2019113369A RU2765074C2 RU 2765074 C2 RU2765074 C2 RU 2765074C2 RU 2019113369 A RU2019113369 A RU 2019113369A RU 2019113369 A RU2019113369 A RU 2019113369A RU 2765074 C2 RU2765074 C2 RU 2765074C2
- Authority
- RU
- Russia
- Prior art keywords
- capsule
- shell
- capsule shell
- capsules
- temperature
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/077—Manufacturing capsule shells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
- F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
- F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
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- F26B21/25—
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- F26B21/33—
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- F26B21/35—
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- F26B21/37—
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- F26B21/50—
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
- F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S53/00—Package making
- Y10S53/90—Capsules
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Drying Of Solid Materials (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Disintegrating Or Milling (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662431569P | 2016-12-08 | 2016-12-08 | |
| US62/431,569 | 2016-12-08 | ||
| PCT/US2017/065398 WO2018107080A1 (en) | 2016-12-08 | 2017-12-08 | A method to relieve stress in capsule shells to reduce propensity to break |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2019113369A RU2019113369A (ru) | 2021-01-13 |
| RU2019113369A3 RU2019113369A3 (enExample) | 2021-03-18 |
| RU2765074C2 true RU2765074C2 (ru) | 2022-01-25 |
Family
ID=62491357
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019113369A RU2765074C2 (ru) | 2016-12-08 | 2017-12-08 | Способ снятия напряжения в оболочках капсул для уменьшения предрасположенности к разлому |
| RU2019112049A RU2745334C9 (ru) | 2016-12-08 | 2017-12-08 | Ускоренное высушивание мягких капсул в регулируемой среде |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019112049A RU2745334C9 (ru) | 2016-12-08 | 2017-12-08 | Ускоренное высушивание мягких капсул в регулируемой среде |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11026865B2 (enExample) |
| EP (2) | EP3551158B1 (enExample) |
| JP (2) | JP7013465B2 (enExample) |
| KR (2) | KR102328603B1 (enExample) |
| CN (2) | CN109923360B (enExample) |
| AU (2) | AU2017374037B2 (enExample) |
| BR (1) | BR112019010069A2 (enExample) |
| CA (1) | CA3045127A1 (enExample) |
| CO (2) | CO2019005095A2 (enExample) |
| ES (1) | ES2927068T3 (enExample) |
| IL (2) | IL266694B2 (enExample) |
| MX (2) | MX2019005930A (enExample) |
| RU (2) | RU2765074C2 (enExample) |
| WO (2) | WO2018107080A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102328603B1 (ko) * | 2016-12-08 | 2021-11-18 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 파손 가능성을 감소시키기 위해 캡슐 쉘 내의 응력을 완화시키는 방법 |
| JP7770308B2 (ja) * | 2019-08-30 | 2025-11-14 | プロキャップス ソシエダッド アノニマ | 寒天マトリックスを有する耐熱性チュアブル経口投与剤形およびその製造方法 |
| US20210154099A1 (en) * | 2019-11-22 | 2021-05-27 | Karl Wei Cao | Top liquid fill method and apparatus for hard capsules |
| WO2021118558A1 (en) * | 2019-12-11 | 2021-06-17 | W.L. Gore & Associates, Inc, | Methods for evaluating vapor pump performance |
| CN115792141B (zh) * | 2023-01-06 | 2023-05-02 | 广州兰泰仪器有限公司 | 一种提高水活度仪平衡检测效率的方法及系统 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200191A (en) * | 1991-09-11 | 1993-04-06 | Banner Gelatin Products Corp. | Softgel manufacturing process |
| US8790692B2 (en) * | 2009-09-09 | 2014-07-29 | Patheon Pharmaceuticals Inc. | Break resistant gel capsule |
| US20150342892A1 (en) * | 2013-03-15 | 2015-12-03 | Capsugel Belgium Nv | Enteric coating for soft capsule |
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| US1330238A (en) * | 1918-06-03 | 1920-02-10 | Buffalo Forge Co | Method of and apparatus for drying, conditioning, and regulating the moisture content of hygroscopic materials |
| IE45260B1 (en) | 1976-01-23 | 1982-07-28 | Fisons Ltd | Pelletised or granular medicament formulation |
| FI63335B (fi) | 1979-02-02 | 1983-02-28 | Orion Yhtymae Oy | Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne |
| DE3022136C2 (de) | 1980-06-13 | 1986-07-17 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren zum Abfüllen von Phospholipide enthaltenden pharmazeutischen Massen in Hartkapseln |
| US4506453A (en) | 1982-09-29 | 1985-03-26 | Tennessee Valley Authority | Enhanced heat transfer process by forced gas recirculation |
| US4539060A (en) * | 1983-02-18 | 1985-09-03 | Warner-Lambert Company | Apparatus and method of sealing capsules |
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| US4720924A (en) * | 1986-11-03 | 1988-01-26 | R & J Engineering Corporation | Microwave drying of pharmaceutical gelatin capsules |
| EP0736162B1 (en) * | 1994-01-07 | 1999-04-28 | Thermtech A/S | A process and a device in drying of organic and/or unorganic materials |
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| KR102328603B1 (ko) * | 2016-12-08 | 2021-11-18 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 파손 가능성을 감소시키기 위해 캡슐 쉘 내의 응력을 완화시키는 방법 |
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-
2017
- 2017-12-08 KR KR1020197015395A patent/KR102328603B1/ko active Active
- 2017-12-08 KR KR1020197014547A patent/KR102475555B1/ko active Active
- 2017-12-08 RU RU2019113369A patent/RU2765074C2/ru active
- 2017-12-08 JP JP2019530494A patent/JP7013465B2/ja active Active
- 2017-12-08 IL IL266694A patent/IL266694B2/en unknown
- 2017-12-08 MX MX2019005930A patent/MX2019005930A/es unknown
- 2017-12-08 US US16/467,436 patent/US11026865B2/en active Active
- 2017-12-08 ES ES17877660T patent/ES2927068T3/es active Active
- 2017-12-08 EP EP17878382.5A patent/EP3551158B1/en active Active
- 2017-12-08 AU AU2017374037A patent/AU2017374037B2/en active Active
- 2017-12-08 CA CA3045127A patent/CA3045127A1/en active Pending
- 2017-12-08 MX MX2019005956A patent/MX2019005956A/es unknown
- 2017-12-08 CN CN201780069164.1A patent/CN109923360B/zh active Active
- 2017-12-08 WO PCT/US2017/065398 patent/WO2018107080A1/en not_active Ceased
- 2017-12-08 BR BR112019010069-5A patent/BR112019010069A2/pt not_active Application Discontinuation
- 2017-12-08 JP JP2019531045A patent/JP7129977B2/ja active Active
- 2017-12-08 AU AU2017371180A patent/AU2017371180B2/en active Active
- 2017-12-08 RU RU2019112049A patent/RU2745334C9/ru active
- 2017-12-08 EP EP17877660.5A patent/EP3551950B1/en active Active
- 2017-12-08 IL IL266695A patent/IL266695B/en unknown
- 2017-12-08 US US16/467,408 patent/US12161605B2/en active Active
- 2017-12-08 CN CN201780070689.7A patent/CN110167510B/zh not_active Expired - Fee Related
- 2017-12-08 WO PCT/US2017/065290 patent/WO2018107019A1/en not_active Ceased
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2019
- 2019-05-17 CO CONC2019/0005095A patent/CO2019005095A2/es unknown
- 2019-05-22 CO CONC2019/0005238A patent/CO2019005238A2/es unknown
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2024
- 2024-10-08 US US18/908,883 patent/US20250025377A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200191A (en) * | 1991-09-11 | 1993-04-06 | Banner Gelatin Products Corp. | Softgel manufacturing process |
| US8790692B2 (en) * | 2009-09-09 | 2014-07-29 | Patheon Pharmaceuticals Inc. | Break resistant gel capsule |
| US20150342892A1 (en) * | 2013-03-15 | 2015-12-03 | Capsugel Belgium Nv | Enteric coating for soft capsule |
Non-Patent Citations (5)
| Title |
|---|
| Dejugnat, Cet al., (2007). Membrane Densification of Heated Polyelectrolyte Multilayer Capsules Characterized by Soft X-ray Microscopy. Advanced Materials, 19(10), 1331-1336, найдено онлайн, найдено в Интернете: https://doi:10.1002/adma.200602643. стр. 1332. * |
| G. Aguirre-Alvarez, The effect of drying temperature on mechanical properties of pig skin gelatin films. El efecto de la temperatura de secado sobre las propiedades mecánicas de películas de gelatina de cerdo, CyTA - Journal of Food, 9:3, 243-249, найдено онлайн, найдено в Интернете: https://www.tandfonline.com/doi/pdf/10.1080/19476337.2010.523902?needAccess=true, фиг. 3. * |
| Köhler K. et al., Heat Treatment of Polyelectrolyte Multilayer Capsules: A Versatile Method for Encapsulation // Adv. Funct. Mater. 2007. Vol. 17, 13. P. 2053-2061, найдено онлайн, найдено в Интернете: https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.200600593. * |
| Mara Coppola, Phase Diagram of Gelatin Plasticized by Water and Glycerol, Macromolecular Symposia, 273(1), 56-65. First published: 16 December 2008, найдено онлайн, найдено в Интернете: https://doi.org/10.1002/masy.200851308. * |
| Mara Coppola, Phase Diagram of Gelatin Plasticized by Water and Glycerol, Macromolecular Symposia, 273(1), 56-65. First published: 16 December 2008, найдено онлайн, найдено в Интернете: https://doi.org/10.1002/masy.200851308. Dejugnat, Cet al., (2007). Membrane Densification of Heated Polyelectrolyte Multilayer Capsules Characterized by Soft X-ray Microscopy. Advanced Materials, 19(10), 1331-1336, найдено онлайн, найдено в Интернете: https://doi:10.1002/adma.200602643. стр. 1332. Köhler K. et al., Heat Treatment of Polyelectrolyte Multilayer Capsules: A Versatile Method for Encapsulation // Adv. Funct. Mater. 2007. Vol. 17, 13. P. 2053-2061, найдено онлайн, найдено в Интернете: https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.200600593. G. Aguirre-Alvarez, The effect of drying temperature on mechanical properties of pig skin gelatin films. El efecto de la temperatura de secado sobre las propiedades mecánicas de películas de gelatina de cerdo, CyTA - Journal of Fo * |
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