CO2019005238A2 - Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse - Google Patents

Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse

Info

Publication number
CO2019005238A2
CO2019005238A2 CONC2019/0005238A CO2019005238A CO2019005238A2 CO 2019005238 A2 CO2019005238 A2 CO 2019005238A2 CO 2019005238 A CO2019005238 A CO 2019005238A CO 2019005238 A2 CO2019005238 A2 CO 2019005238A2
Authority
CO
Colombia
Prior art keywords
capsule shell
reduce
tension
capsule
decrease
Prior art date
Application number
CONC2019/0005238A
Other languages
English (en)
Inventor
Lester David Fulper
Norton Hart
Original Assignee
Scherer Technologies Llc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Llc R P filed Critical Scherer Technologies Llc R P
Publication of CO2019005238A2 publication Critical patent/CO2019005238A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
    • F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/004—Nozzle assemblies; Air knives; Air distributors; Blow boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/02—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
    • F26B21/04—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/08—Humidity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/10—Temperature; Pressure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/12—Velocity of flow; Quantity of flow, e.g. by varying fan speed, by modifying cross flow area
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Drying Of Solid Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Disintegrating Or Milling (AREA)

Abstract

Un método de tratamiento de una cubierta de cápsula blanda o dura para reducir o disminuir la tensión en la cubierta de la cápsula. El método incluye una etapa de calentamiento de al menos una porción de la cubierta de cápsula blanda o dura a una temperatura por encima de una temperatura de transición vítrea de la cubierta de la cápsula, pero por debajo de una temperatura de fusión de la cubierta de la cápsula durante un tiempo suficiente para reducir la tensión interna en la cubierta de la cápsula. El método se puede utilizar para reducir el agrietamiento de cubiertas de cápsulas duras o blandas por medio de la aplicación del tratamiento de térmico a las cubiertas de las cápsulas rellenas después de la fabricación y llenado.
CONC2019/0005238A 2016-12-08 2019-05-22 Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse CO2019005238A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662431569P 2016-12-08 2016-12-08
PCT/US2017/065398 WO2018107080A1 (en) 2016-12-08 2017-12-08 A method to relieve stress in capsule shells to reduce propensity to break

Publications (1)

Publication Number Publication Date
CO2019005238A2 true CO2019005238A2 (es) 2019-05-31

Family

ID=62491357

Family Applications (2)

Application Number Title Priority Date Filing Date
CONC2019/0005095A CO2019005095A2 (es) 2016-12-08 2019-05-17 Secado acelerado de cápsulas blandas en un entorno controlado
CONC2019/0005238A CO2019005238A2 (es) 2016-12-08 2019-05-22 Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CONC2019/0005095A CO2019005095A2 (es) 2016-12-08 2019-05-17 Secado acelerado de cápsulas blandas en un entorno controlado

Country Status (14)

Country Link
US (2) US20200069524A1 (es)
EP (2) EP3551158A4 (es)
JP (2) JP7129977B2 (es)
KR (2) KR102475555B1 (es)
CN (2) CN110167510B (es)
AU (2) AU2017371180B2 (es)
BR (2) BR112019010644A2 (es)
CA (2) CA3041560A1 (es)
CO (2) CO2019005095A2 (es)
ES (1) ES2927068T3 (es)
IL (2) IL266694B2 (es)
MX (2) MX2019005930A (es)
RU (2) RU2745334C9 (es)
WO (2) WO2018107019A1 (es)

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CN115792141B (zh) * 2023-01-06 2023-05-02 广州兰泰仪器有限公司 一种提高水活度仪平衡检测效率的方法及系统

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Also Published As

Publication number Publication date
AU2017374037B2 (en) 2023-02-23
CN109923360A (zh) 2019-06-21
JP2020501101A (ja) 2020-01-16
RU2765074C2 (ru) 2022-01-25
ES2927068T3 (es) 2022-11-02
IL266694A (en) 2019-07-31
WO2018107080A1 (en) 2018-06-14
EP3551158A1 (en) 2019-10-16
KR102328603B1 (ko) 2021-11-18
IL266694B2 (en) 2023-03-01
US20200069525A1 (en) 2020-03-05
AU2017374037A1 (en) 2019-05-16
US11026865B2 (en) 2021-06-08
WO2018107019A1 (en) 2018-06-14
RU2019113369A3 (es) 2021-03-18
MX2019005930A (es) 2019-07-08
RU2745334C2 (ru) 2021-03-24
CN110167510B (zh) 2021-12-14
AU2017371180B2 (en) 2023-05-11
IL266695A (en) 2019-07-31
RU2019112049A (ru) 2021-01-12
EP3551950A1 (en) 2019-10-16
RU2019112049A3 (es) 2021-01-21
EP3551950B1 (en) 2022-06-22
JP7129977B2 (ja) 2022-09-02
KR20190069576A (ko) 2019-06-19
BR112019010644A2 (pt) 2019-10-01
BR112019010069A2 (pt) 2019-08-20
IL266694B (en) 2022-11-01
CO2019005095A2 (es) 2019-05-31
IL266695B (en) 2022-09-01
EP3551158A4 (en) 2020-06-03
KR102475555B1 (ko) 2022-12-07
JP2020500643A (ja) 2020-01-16
RU2019113369A (ru) 2021-01-13
EP3551950A4 (en) 2020-06-03
CA3041560A1 (en) 2018-06-14
CN110167510A (zh) 2019-08-23
JP7013465B2 (ja) 2022-01-31
CA3045127A1 (en) 2018-06-14
KR20190084990A (ko) 2019-07-17
AU2017371180A1 (en) 2019-05-23
CN109923360B (zh) 2022-02-11
RU2745334C9 (ru) 2021-05-24
MX2019005956A (es) 2019-07-10
US20200069524A1 (en) 2020-03-05

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