MX2019005930A - Secado acelerado de capsulas blandas en un entorno controlado. - Google Patents

Secado acelerado de capsulas blandas en un entorno controlado.

Info

Publication number
MX2019005930A
MX2019005930A MX2019005930A MX2019005930A MX2019005930A MX 2019005930 A MX2019005930 A MX 2019005930A MX 2019005930 A MX2019005930 A MX 2019005930A MX 2019005930 A MX2019005930 A MX 2019005930A MX 2019005930 A MX2019005930 A MX 2019005930A
Authority
MX
Mexico
Prior art keywords
soft capsules
relative humidity
drying
capsules
controlled environment
Prior art date
Application number
MX2019005930A
Other languages
English (en)
Inventor
Richard Hart Norton
David Fulper Lester
Original Assignee
Scherer Technologies Llc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Llc R P filed Critical Scherer Technologies Llc R P
Publication of MX2019005930A publication Critical patent/MX2019005930A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
    • F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/004—Nozzle assemblies; Air knives; Air distributors; Blow boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/02—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
    • F26B21/04—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/08—Humidity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/10—Temperature; Pressure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/12—Velocity of flow; Quantity of flow, e.g. by varying fan speed, by modifying cross flow area
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Manufacturing & Machinery (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Drying Of Solid Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Disintegrating Or Milling (AREA)

Abstract

Un método de secado de las cápsulas blandas que incluye los pasos de: a) suministrar un flujo de aire a dichas cápsulas blandas a una velocidad del aire a través de las cápsulas blandas de aproximadamente 0.15 m/s a aproximadamente 13 m/s; b) aumentar, con el tiempo, una temperatura de secado a la que dichas cápsulas blandas se exponen mientras aseguran que la temperatura de secado permanece debajo de la temperatura de fusión de una cubierta de cápsula de las cápsulas blandas; c) exponer dichas cápsulas blandas a una humedad relativa inicial de aproximadamente 49 % de HR a aproximadamente 79% de HR; d) disminuir la humedad relativa a la cual las cápsulas blandas se exponen mientras las cápsulas secan hasta que un equilibrio de la humedad relativa de las cápsulas blandas alcanza una humedad relativa deseada; y e) exponer las cápsulas blandas del paso d) a una temperatura de aproximadamente 20-25 °C. También se divulga un sistema de secado para realizar el método.
MX2019005930A 2016-12-08 2017-12-08 Secado acelerado de capsulas blandas en un entorno controlado. MX2019005930A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662431569P 2016-12-08 2016-12-08
PCT/US2017/065290 WO2018107019A1 (en) 2016-12-08 2017-12-08 Accelerated drying of soft capsules in a controlled environment

Publications (1)

Publication Number Publication Date
MX2019005930A true MX2019005930A (es) 2019-07-08

Family

ID=62491357

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019005956A MX2019005956A (es) 2016-12-08 2017-12-08 Un metodo para reducir la tension en la cubierta de la capsula para disminuir la propension a romperse.
MX2019005930A MX2019005930A (es) 2016-12-08 2017-12-08 Secado acelerado de capsulas blandas en un entorno controlado.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2019005956A MX2019005956A (es) 2016-12-08 2017-12-08 Un metodo para reducir la tension en la cubierta de la capsula para disminuir la propension a romperse.

Country Status (14)

Country Link
US (2) US11026865B2 (es)
EP (2) EP3551158B1 (es)
JP (2) JP7129977B2 (es)
KR (2) KR102328603B1 (es)
CN (2) CN110167510B (es)
AU (2) AU2017371180B2 (es)
BR (1) BR112019010069A2 (es)
CA (2) CA3045127A1 (es)
CO (2) CO2019005095A2 (es)
ES (1) ES2927068T3 (es)
IL (2) IL266694B2 (es)
MX (2) MX2019005956A (es)
RU (2) RU2765074C2 (es)
WO (2) WO2018107019A1 (es)

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CN115792141B (zh) * 2023-01-06 2023-05-02 广州兰泰仪器有限公司 一种提高水活度仪平衡检测效率的方法及系统

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Also Published As

Publication number Publication date
CO2019005095A2 (es) 2019-05-31
EP3551158B1 (en) 2024-07-10
CN110167510A (zh) 2019-08-23
EP3551950B1 (en) 2022-06-22
BR112019010069A2 (pt) 2019-08-20
IL266695B (en) 2022-09-01
CN110167510B (zh) 2021-12-14
RU2019112049A (ru) 2021-01-12
BR112019010644A2 (pt) 2019-10-01
EP3551950A1 (en) 2019-10-16
EP3551158A1 (en) 2019-10-16
CN109923360B (zh) 2022-02-11
CN109923360A (zh) 2019-06-21
JP7013465B2 (ja) 2022-01-31
RU2745334C9 (ru) 2021-05-24
AU2017371180A1 (en) 2019-05-23
RU2019113369A (ru) 2021-01-13
CA3045127A1 (en) 2018-06-14
AU2017371180B2 (en) 2023-05-11
EP3551158C0 (en) 2024-07-10
MX2019005956A (es) 2019-07-10
WO2018107019A1 (en) 2018-06-14
IL266694A (en) 2019-07-31
CA3041560A1 (en) 2018-06-14
KR102328603B1 (ko) 2021-11-18
WO2018107080A1 (en) 2018-06-14
RU2745334C2 (ru) 2021-03-24
EP3551950A4 (en) 2020-06-03
KR102475555B1 (ko) 2022-12-07
RU2765074C2 (ru) 2022-01-25
EP3551158A4 (en) 2020-06-03
KR20190084990A (ko) 2019-07-17
AU2017374037B2 (en) 2023-02-23
IL266694B (en) 2022-11-01
IL266695A (en) 2019-07-31
KR20190069576A (ko) 2019-06-19
AU2017374037A1 (en) 2019-05-16
US20200069525A1 (en) 2020-03-05
RU2019113369A3 (es) 2021-03-18
RU2019112049A3 (es) 2021-01-21
JP2020501101A (ja) 2020-01-16
IL266694B2 (en) 2023-03-01
CO2019005238A2 (es) 2019-05-31
JP2020500643A (ja) 2020-01-16
ES2927068T3 (es) 2022-11-02
US11026865B2 (en) 2021-06-08
JP7129977B2 (ja) 2022-09-02
US20200069524A1 (en) 2020-03-05

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