CO2019005095A2 - Secado acelerado de cápsulas blandas en un entorno controlado - Google Patents
Secado acelerado de cápsulas blandas en un entorno controladoInfo
- Publication number
- CO2019005095A2 CO2019005095A2 CONC2019/0005095A CO2019005095A CO2019005095A2 CO 2019005095 A2 CO2019005095 A2 CO 2019005095A2 CO 2019005095 A CO2019005095 A CO 2019005095A CO 2019005095 A2 CO2019005095 A2 CO 2019005095A2
- Authority
- CO
- Colombia
- Prior art keywords
- soft capsules
- relative humidity
- drying
- capsules
- soft
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/077—Manufacturing capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
- F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
- F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/004—Nozzle assemblies; Air knives; Air distributors; Blow boxes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/02—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
- F26B21/04—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/06—Controlling, e.g. regulating, parameters of gas supply
- F26B21/08—Humidity
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/06—Controlling, e.g. regulating, parameters of gas supply
- F26B21/10—Temperature; Pressure
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/06—Controlling, e.g. regulating, parameters of gas supply
- F26B21/12—Velocity of flow; Quantity of flow, e.g. by varying fan speed, by modifying cross flow area
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
- F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S53/00—Package making
- Y10S53/90—Capsules
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Drying Of Solid Materials (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Disintegrating Or Milling (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662431569P | 2016-12-08 | 2016-12-08 | |
| PCT/US2017/065290 WO2018107019A1 (en) | 2016-12-08 | 2017-12-08 | Accelerated drying of soft capsules in a controlled environment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2019005095A2 true CO2019005095A2 (es) | 2019-05-31 |
Family
ID=62491357
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2019/0005095A CO2019005095A2 (es) | 2016-12-08 | 2019-05-17 | Secado acelerado de cápsulas blandas en un entorno controlado |
| CONC2019/0005238A CO2019005238A2 (es) | 2016-12-08 | 2019-05-22 | Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2019/0005238A CO2019005238A2 (es) | 2016-12-08 | 2019-05-22 | Un método para reducir la tensión en la cubierta de la cápsula para disminuir la propensión a romperse |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11026865B2 (enExample) |
| EP (2) | EP3551158B1 (enExample) |
| JP (2) | JP7129977B2 (enExample) |
| KR (2) | KR102475555B1 (enExample) |
| CN (2) | CN109923360B (enExample) |
| AU (2) | AU2017374037B2 (enExample) |
| BR (1) | BR112019010069A2 (enExample) |
| CA (2) | CA3045127A1 (enExample) |
| CO (2) | CO2019005095A2 (enExample) |
| ES (1) | ES2927068T3 (enExample) |
| IL (2) | IL266694B2 (enExample) |
| MX (2) | MX2019005930A (enExample) |
| RU (2) | RU2765074C2 (enExample) |
| WO (2) | WO2018107019A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018107019A1 (en) | 2016-12-08 | 2018-06-14 | R.P. Scherer Technologies, Llc | Accelerated drying of soft capsules in a controlled environment |
| US20220249368A1 (en) * | 2019-08-30 | 2022-08-11 | Procaps S.A. | Heat resistant chewable oral form with an agar matrix and manufacturing process thereof |
| US20210154099A1 (en) * | 2019-11-22 | 2021-05-27 | Karl Wei Cao | Top liquid fill method and apparatus for hard capsules |
| CN114787512B (zh) * | 2019-12-11 | 2024-07-05 | W.L.戈尔及同仁股份有限公司 | 用于评估蒸气泵性能的方法 |
| CN115792141B (zh) * | 2023-01-06 | 2023-05-02 | 广州兰泰仪器有限公司 | 一种提高水活度仪平衡检测效率的方法及系统 |
Family Cites Families (57)
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| US1330238A (en) * | 1918-06-03 | 1920-02-10 | Buffalo Forge Co | Method of and apparatus for drying, conditioning, and regulating the moisture content of hygroscopic materials |
| IE45260B1 (en) | 1976-01-23 | 1982-07-28 | Fisons Ltd | Pelletised or granular medicament formulation |
| FI63335B (fi) | 1979-02-02 | 1983-02-28 | Orion Yhtymae Oy | Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne |
| DE3022136C2 (de) | 1980-06-13 | 1986-07-17 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren zum Abfüllen von Phospholipide enthaltenden pharmazeutischen Massen in Hartkapseln |
| US4506453A (en) | 1982-09-29 | 1985-03-26 | Tennessee Valley Authority | Enhanced heat transfer process by forced gas recirculation |
| US4539060A (en) * | 1983-02-18 | 1985-09-03 | Warner-Lambert Company | Apparatus and method of sealing capsules |
| JPS61100519A (ja) * | 1984-10-23 | 1986-05-19 | Shin Etsu Chem Co Ltd | 医薬用硬質カプセル |
| CH674800A5 (enExample) | 1986-03-12 | 1990-07-31 | Warner Lambert Co | |
| US4720924A (en) * | 1986-11-03 | 1988-01-26 | R & J Engineering Corporation | Microwave drying of pharmaceutical gelatin capsules |
| US5200191A (en) | 1991-09-11 | 1993-04-06 | Banner Gelatin Products Corp. | Softgel manufacturing process |
| EP0736162B1 (en) * | 1994-01-07 | 1999-04-28 | Thermtech A/S | A process and a device in drying of organic and/or unorganic materials |
| US5682733A (en) | 1996-05-09 | 1997-11-04 | Perrone; Aldo | Apparatus for enrobing tablets |
| US6228394B1 (en) | 1997-10-14 | 2001-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Supercritical fluid extraction of mould lubricant from hard shell capsules |
| US5960563A (en) * | 1998-01-12 | 1999-10-05 | Big Beans Holding, Ltd. | Extraction and drying apparatus |
| US8256135B2 (en) * | 1999-05-28 | 2012-09-04 | Thermapure, Inc. | Method for removing or treating harmful biological and chemical substances within structures and enclosures |
| US6340473B1 (en) | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
| EP1323404B1 (en) | 2000-08-29 | 2013-10-16 | Nisshin Kasei Co.,Ltd. | Hard capsule |
| ES2334973T3 (es) | 2000-12-29 | 2010-03-18 | Swiss Caps Rechte Und Lizenzen Ag | Procedimiento y dispositivo para la obtencion de cuerpos moldeados a partir de un material biopolimero. |
| AU2002315779B2 (en) | 2001-07-05 | 2007-03-22 | Wakunaga Pharmaceutical Co.,Ltd | Soft capsules |
| JP2003116507A (ja) | 2001-10-10 | 2003-04-22 | Akira Shibazaki | 水分含有食品の乾燥方法及び装置 |
| US6884060B2 (en) | 2001-11-02 | 2005-04-26 | R.P. Scherer Technologies, Inc. | Apparatus for manufacturing encapsulated products |
| DE10157755A1 (de) * | 2001-11-27 | 2003-06-12 | Henkel Kgaa | Wirkstoffhaltige Gelkapseln und ihre Verwendung |
| CN1483393A (zh) | 2002-09-17 | 2004-03-24 | 潮州市药用胶囊厂 | 一种淀粉空心胶囊及其生产工艺 |
| CA2510465A1 (en) * | 2002-12-18 | 2004-07-08 | Pain Therapeutics | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
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| DK2603208T3 (da) * | 2010-08-10 | 2014-09-15 | Rp Scherer Technologies Llc | Fremgangsmåde til fremstilling af en stabil softgelkapsel indeholdende mikroindkapslede probiotiske bakterier |
| EA201300255A1 (ru) | 2010-08-23 | 2013-06-28 | Такеда Гмбх | Увлажненные частицы, содержащие терапевтически активное вещество |
| JP5693116B2 (ja) | 2010-09-26 | 2015-04-01 | 日本テトラパック株式会社 | 包装充填装置及び包装充填方法 |
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| CN102283779A (zh) | 2011-06-14 | 2011-12-21 | 贵州地道药业有限公司 | 一种软胶囊干燥的新技术 |
| CN103256806B (zh) * | 2012-02-20 | 2015-09-02 | 艾默生电气公司 | 用于干燥材料的装置和方法 |
| EP4385503A3 (en) | 2013-03-15 | 2024-08-28 | Capsugel Belgium NV | Enteric coating for soft capsule |
| US10646452B2 (en) | 2013-03-15 | 2020-05-12 | New Jersey Institute Of Technology | System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process |
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| DE102015205338A1 (de) * | 2015-03-24 | 2016-09-29 | Cefla Deutschland Gmbh | Trocknungsvorrichtung |
| CN104991591B (zh) | 2015-05-23 | 2018-05-04 | 浙江益立胶囊股份有限公司 | 一种用于胶囊干燥及储存的控制系统 |
| CN105674699B (zh) * | 2016-02-02 | 2018-04-20 | 安徽恒昊科技有限公司 | 一种快速高湿干燥灭菌的工艺方法 |
| CN105987587A (zh) | 2016-06-28 | 2016-10-05 | 无锡市中谊药化机械有限公司 | 一种软胶囊滚动风干干燥方法及其装置 |
| WO2018107019A1 (en) * | 2016-12-08 | 2018-06-14 | R.P. Scherer Technologies, Llc | Accelerated drying of soft capsules in a controlled environment |
| US10422579B2 (en) * | 2017-05-02 | 2019-09-24 | Auto Cure Llc | Automated drying and curing chamber |
| EP3655666A4 (en) * | 2017-07-20 | 2020-11-18 | Commonwealth Scientific and Industrial Research Organisation | DRYING PROCESS AND APPARATUS |
| US10590594B2 (en) * | 2017-11-28 | 2020-03-17 | Elberto Berdut-Teruel | Magnetic induction heating system and dehydrator |
| CN210197946U (zh) * | 2019-05-07 | 2020-03-27 | 于雄青 | 一种带蒸发器的软胶囊干燥设备 |
-
2017
- 2017-12-08 WO PCT/US2017/065290 patent/WO2018107019A1/en not_active Ceased
- 2017-12-08 AU AU2017374037A patent/AU2017374037B2/en active Active
- 2017-12-08 US US16/467,436 patent/US11026865B2/en active Active
- 2017-12-08 CA CA3045127A patent/CA3045127A1/en active Pending
- 2017-12-08 JP JP2019531045A patent/JP7129977B2/ja active Active
- 2017-12-08 EP EP17878382.5A patent/EP3551158B1/en active Active
- 2017-12-08 CN CN201780069164.1A patent/CN109923360B/zh active Active
- 2017-12-08 IL IL266694A patent/IL266694B2/en unknown
- 2017-12-08 RU RU2019113369A patent/RU2765074C2/ru active
- 2017-12-08 EP EP17877660.5A patent/EP3551950B1/en active Active
- 2017-12-08 MX MX2019005930A patent/MX2019005930A/es unknown
- 2017-12-08 CA CA3041560A patent/CA3041560A1/en active Pending
- 2017-12-08 US US16/467,408 patent/US12161605B2/en active Active
- 2017-12-08 BR BR112019010069A patent/BR112019010069A2/pt not_active Application Discontinuation
- 2017-12-08 KR KR1020197014547A patent/KR102475555B1/ko active Active
- 2017-12-08 WO PCT/US2017/065398 patent/WO2018107080A1/en not_active Ceased
- 2017-12-08 MX MX2019005956A patent/MX2019005956A/es unknown
- 2017-12-08 IL IL266695A patent/IL266695B/en unknown
- 2017-12-08 KR KR1020197015395A patent/KR102328603B1/ko active Active
- 2017-12-08 JP JP2019530494A patent/JP7013465B2/ja active Active
- 2017-12-08 RU RU2019112049A patent/RU2745334C9/ru active
- 2017-12-08 CN CN201780070689.7A patent/CN110167510B/zh not_active Expired - Fee Related
- 2017-12-08 AU AU2017371180A patent/AU2017371180B2/en active Active
- 2017-12-08 ES ES17877660T patent/ES2927068T3/es active Active
-
2019
- 2019-05-17 CO CONC2019/0005095A patent/CO2019005095A2/es unknown
- 2019-05-22 CO CONC2019/0005238A patent/CO2019005238A2/es unknown
-
2024
- 2024-10-08 US US18/908,883 patent/US20250025377A1/en active Pending
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